Human epilepsy is a major public health problem affecting
approximately 2 persons per 1000. It is particularly frequent in
ohildren where convul sions may lead to brain damage and subsequent
seizure activity in adulthood. Temporal lobe epilepsy (synonyms
include limbic epilepsy. psychomotor epilepsy and complex partial
epilepsy) is the most devastating form of epilepsy in the adult
population since: a) it is often extremely resistant to currently
available anticonvulsant drugs (i.e ** it is more resistant than
tonico-clonic or grand mal seizures) and b) it includes loss of
consciousness. thereby limiting performance of many normal
functions and leaving the individual susceptible to bodily injury.
It is also associated with nerve cell loss. in particular in the
hippocampus and other structures of the temporal lobes. In order to
promote an appropriate therapy it is essential to understand the
etiology of seizures and its relationship to brain damage. Basic
research on epilepsy also provides a very useful vehicle to learn
about the way the brain functions under normal conditions. For
instance. much of our present understanding of the mechanisms of
action of GABA and benzo diazepines. control of neuronal activity.
etc. has been derived from such stUdies.
General
Imprint: |
Springer-Verlag New York
|
Country of origin: |
United States |
Series: |
Advances in Experimental Medicine and Biology, 203 |
Release date: |
November 2012 |
First published: |
1986 |
Authors: |
Robert Schwarcz
• Yehezkel Ben-Ari
|
Dimensions: |
254 x 178 x 38mm (L x W x T) |
Format: |
Paperback
|
Pages: |
735 |
Edition: |
Softcover reprint of the original 1st ed. 1986 |
ISBN-13: |
978-1-4684-7973-7 |
Categories: |
Books >
Science & Mathematics >
Biology, life sciences >
Biochemistry >
General
|
LSN: |
1-4684-7973-3 |
Barcode: |
9781468479737 |
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