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Books > Professional & Technical > Industrial chemistry & manufacturing technologies > Industrial chemistry > Pharmaceutical technology
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Peptide and Protein Drug Analysis (Hardcover)
Loot Price: R6,828
Discovery Miles 68 280
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Peptide and Protein Drug Analysis (Hardcover)
Expected to ship within 12 - 19 working days
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Furthering efforts to simulate the potency and specificity
exhibited by peptides and proteins in healthy cells, this
remarkable reference supplies pharmaceutical scientists with a
wealth of techniques for tapping the enormous therapeutic potential
of these molecules-providing a solid basis of knowledge for new
drug design.
Provides a broad, comprehensive overview of peptides and proteins
as mediators of cell movement, proliferation, differentiation, and
communication.
Written by more than 50 leading international authorities, Peptides
and Protein Drug Analysis
discusses strategies for dealing with the complexity of peptides
and proteins in conformational flexibility and amino acid sequence
variability
analyzes drug formulations facilitated by solid-phase peptide
synthesis and recombinant DNA technology
examines chemical purity analysis by high-pressure chromatographic,
capillary electrophoretic, gel electrophoretic, and isoelectric
focusing methods
highlights drug design elements derived from protein folding,
bioinformatics, and computational chemistry
demonstrates uses of unnatural mutagenesis and combinatorial
chemistry
explores mass spectrometry, protein sequence, and carbohydrate
analysis
illustrates bioassays and other new functional analysis methods
surveys spectroscopic techniques such as ultraviolet, fluorescence,
Fourier transform infrared, and nuclear magnetic resonance (NMR)
addresses ways of distinguishing between levels of therapeutic and
endogenous agents in cells
reviews structural analysis tools such as ultracentrifugation and
light, X-ray, and neutron scattering
and more
Featuring over 3400 bibliographic citations and more than 500
tables, equations, and illustrations, Peptide and Protein Drug
Analysis is a must-read resource for pharmacists; pharmacologists;
analytical, organic, and pharmaceutical chemists; cell and
molecular biologists; biochemists; and upper-level undergraduate
and graduate students in these disciplines.
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