Oxidative Stress and Neuroprotection (Paperback, 2006 ed.)

This book deals with basic and clinical aspects of monoamine oxidase (MAO) subtypes A and B highlighting its importance in neurological and psychiatric diseases. Consequently the therapeutic actions of MAO-A and -B inhibitors in Parkinson's disease (PK) and depression are the focus of several chapters. As MAO is the basis of the development of the "oxidative stress hypothesis" of PD, several chapters are devoted to iron and iron-induced oxidative stress in various experimental studies and clinical conditions. Based on these findings, new compounds have been developed which not only block MAO, but are in addition, either inhibitors of acetylcholine esterase or have iron chelating properties. The aspect of "preclinical" and "clinical" neuro protection as well as MAO neuroprotection are additional topics covered in this book. MAO, iron and neuroprotection are seen in the framework of general anti Parkinson's therapy with chapters on levodopa, dopaminergic receptor agonists and clinical issues.

General

Imprint:	Springer-Verlag
Country of origin:	Austria
Series:	Journal of Neural Transmission. Supplementa, 71
Release date:	November 2014
First published:	2006
Editors:	S.H. Parvez • Peter Riederer
Dimensions:	279 x 210 x 15mm (L x W x T)
Format:	Paperback
Pages:	264
Edition:	2006 ed.
ISBN-13:	978-3-7091-1736-1
Categories:	Books > Medicine > Clinical & internal medicine > Neurology & clinical neurophysiology
LSN:	3-7091-1736-4
Barcode:	9783709117361

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