The 'epi-(Greek for 'over', 'above')genome', with its rich cache of
highly regulated, structural modifications-including DNA
methylation, histone modifications and histone variants-defines the
moldings and three-dimensional structures of the genomic material
inside the cell nucleus and serves, literally, as a molecular
bridge linking the environment to the genetic materials in our
brain cells. Due to technological and scientific advances in the
field, the field of neuroepigenetics is currently one of the
hottest topics in the basic and clinical neurosciences. The volume
captures some of this vibrant and exciting new research, and
conveys to the reader an up-to-date discussion on the role of
epigenetics across the lifespan of the human brain in health and
disease.
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