This is the fifth and last Volume in the Atlas of Human Central
Nervous System Development Series. It deals with human brain
development during the early first trimester from the third through
the seventh gestational weeks. Serial sections from 14 specimens
are illustrated and annotated in detail, together with 3?D
reconstructions of the brains of eight specimens. The Human Brain
During the Early First Trimester focuses on these major themes:
-Growth of the stockbuilding neural progenitor cells along the
expanding shorelines of the superventricles -Identification of the
mosaic compartments of the neuroepithelium that generate neurons
and neuroglia for different brain structures -Onset of neurogenesis
and expansion of a newly identified meningeal tissue, the
superarachnoid reticulum, which provides space for the growing
brain parenchyma -Migratory paths of neurons in the early-maturing
regions of the brain and the formation of the earliest fiber tracts
Finally, a concluding essay with illustrations and graphs
summarizes the major events of human CNS development. It also
provides a theoretical account of the morphogenetic processes
involved in human CNS development and relates them to current
genetic and molecular research in animal models. This atlas is also
available as part of a five volume set.
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