Parkinson's disease (PD) is characterised by an insidious onset
with slowing of emotional and voluntary movement, muscular
rigidity, postural abnormality and tremor. Parkinson's disease was
first described in 1817 by James Parkinson. It is a progressive,
neurological disease mainly affecting people over the age of 50,
although at least 10% of cases occur at an earlier age. It affects
people of either sex or all ethnic groups. In the normal brain,
some nerve cells produce the chemical dopamine, which transmits
signals within the brain to produce smooth movement of muscles. In
Parkinson's patients, 80 percent or more of these
dopamine-producing cells are damaged, dead, or otherwise
degenerated. This causes the nerve cells to fire wildly, leaving
patients unable to control their movements. This book examines new
research results from around the world.
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