0
Your cart

Your cart is empty

Browse All Departments
  • All Departments
Price
  • R250 - R500 (1)
  • R2,500 - R5,000 (2)
  • -
Status
Brand

Showing 1 - 3 of 3 matches in All Departments

Life-Span Extension - Single-Cell Organisms to Man (Hardcover, 2009 ed.): Christian Sell, Antonello Lorenzini, Holly M.... Life-Span Extension - Single-Cell Organisms to Man (Hardcover, 2009 ed.)
Christian Sell, Antonello Lorenzini, Holly M. Brown-Borg
R4,364 Discovery Miles 43 640 Ships in 10 - 15 working days

In recent years, remarkable discoveries have been made concerning the underlying mechanisms of aging. In Life-Span Extension: Single-Cell Organisms to Man, the editors bring together a range of illuminating perspectives from researchers investigating the aging process in a variety of species. This novel work addresses the aging process in species ranging from yeast to man and, among other subjects, features detailed discussions of the naked mole-rat, an exceptionally long-lived rodent; the relationship between dietary factors/food restriction and aging; and an evolutionary view of the human aging process.

Single mutations that extend life span have been identified in yeast, worms, flies, and mice, whereas studies in humans have identified potentially important markers for successful aging. At the same time, it has been discovered that the genes and pathways identified in these studies involve a surprisingly small set of conserved functions, most of which have been the focus of aging research for some time. For example, the mTOR pathway, a regulator of translation and protein synthesis, has been identified as a common longevity pathway in yeast and Caenorhabditis elegans. In mammals, this pathway intersects with neuroendocrine pathways and with the insulin/insulin-like growth factor pathways, which have been identified as major modulators of life span and aging in both invertebrates and mice.

Novel, emerging technologies and the increasingly wide variety of systems that are now used to study aging and the mechanisms of aging provide enormous opportunities for the identification of common pathways that modulate longevity. It is these common pathways that are the focus of this important volume.

Life-Span Extension - Single-Cell Organisms to Man (Paperback, 2009 ed.): Christian Sell, Antonello Lorenzini, Holly M.... Life-Span Extension - Single-Cell Organisms to Man (Paperback, 2009 ed.)
Christian Sell, Antonello Lorenzini, Holly M. Brown-Borg
R3,096 Discovery Miles 30 960 Ships in 10 - 15 working days

In recent years, remarkable discoveries have been made concerning the underlying mechanisms of aging. In Life-Span Extension: Single-Cell Organisms to Man, the editors bring together a range of illuminating perspectives from researchers investigating the aging process in a variety of species. This novel work addresses the aging process in species ranging from yeast to man and, among other subjects, features detailed discussions of the naked mole-rat, an exceptionally long-lived rodent; the relationship between dietary factors/food restriction and aging; and an evolutionary view of the human aging process.

Single mutations that extend life span have been identified in yeast, worms, flies, and mice, whereas studies in humans have identified potentially important markers for successful aging. At the same time, it has been discovered that the genes and pathways identified in these studies involve a surprisingly small set of conserved functions, most of which have been the focus of aging research for some time. For example, the mTOR pathway, a regulator of translation and protein synthesis, has been identified as a common longevity pathway in yeast and Caenorhabditis elegans. In mammals, this pathway intersects with neuroendocrine pathways and with the insulin/insulin-like growth factor pathways, which have been identified as major modulators of life span and aging in both invertebrates and mice.

Novel, emerging technologies and the increasingly wide variety of systems that are now used to study aging and the mechanisms of aging provide enormous opportunities for the identification of common pathways that modulate longevity. It is these common pathways that are the focus of this important volume.

Hellas (No linguistic content, Paperback): Percy Bysshe Shelley, William Christian Selle Hellas (No linguistic content, Paperback)
Percy Bysshe Shelley, William Christian Selle
R450 R416 Discovery Miles 4 160 Save R34 (8%) Ships in 10 - 15 working days
Free Delivery
Pinterest Twitter Facebook Google+
You may like...
Protein Structural Biology in Biomedical…
C Woodward Hardcover R3,142 Discovery Miles 31 420
Research Handbook on Climate Change…
Jonathan Verschuuren Hardcover R5,265 Discovery Miles 52 650
Reviews of Physiology, Biochemistry and…
Stine Helene Falsig Pedersen Hardcover R3,365 Discovery Miles 33 650
Winning Ugly
Brad Gilbert, Steve Jamison Paperback R334 R302 Discovery Miles 3 020
New Caribbean Junior Readers 2
Diane Brown Paperback R559 Discovery Miles 5 590
Ageless Painless Tennis - Free Yourself…
David Starbuck Smith Hardcover R611 Discovery Miles 6 110
Tyler the Fish and the Lake Erie Bully
Meaghan Fisher Hardcover R451 R423 Discovery Miles 4 230
Routledge Library Editions: Development…
Various Hardcover R12,323 Discovery Miles 123 230
Cloud Clippers - The High-Flying Life of…
Karen M Madigan, Marie R Hubert Hardcover R661 Discovery Miles 6 610
Routledge Handbook of Asian Cities
Richard Hu Hardcover R6,454 Discovery Miles 64 540

 

Partners