A look at important new tools and algorithms for future product modeling systems, based on a seminar at the International Conference and Research Center for Computer Science, Schloss Dagstuhl, Germany, presented by internationally recognised experts in CAD technology.

Michael J. Droller, MD and a panel of experienced clinicians bring their strong background in clinical research to bear on the assessment and management of bladder cancer. Their comprehensive discussion summarizes the state-of-the-art in diagnosis and treatment, based on the latest understanding of bladder cancer's epidemiology, carcinogenesis, and tumor markers. Topics of particular interest include the role of genetics and molecular biology in evaluating bladder cancer clinically, the evaluation of the results of systemic treatment in advanced disease, the current status of tumor markers in bladder cancer, and the means for further study in their applicability. Insightful and evidenced-based, Bladder Cancer: Current Diagnosis and Treatment provides active clinicians and clinical investigators with not only a critical survey of the rapidly expanding research in the area, but also a state-of-the-art tutorial on today's optimal assessment and treatment of bladder cancer.

Systems to support the continuously shrinking product development cycles and the increasing quality requirements need significant enhancements and new approaches.
In this book important new tools and algorithms for future product modeling systems are presented. It is based on a seminar at the International Conference and Research Center for Computer Science, Schloss Dagstuhl, Germany, presented by internationally recognised experts in CAD technology."

Michael J. Droller, MD and a panel of experienced clinicians bring their strong background in clinical research to bear on the assessment and management of bladder cancer. Their comprehensive discussion summarizes the state-of-the-art in diagnosis and treatment, based on the latest understanding of bladder cancer's epidemiology, carcinogenesis, and tumor markers. Topics of particular interest include the role of genetics and molecular biology in evaluating bladder cancer clinically, the evaluation of the results of systemic treatment in advanced disease, the current status of tumor markers in bladder cancer, and the means for further study in their applicability. Insightful and evidenced-based, Bladder Cancer: Current Diagnosis and Treatment provides active clinicians and clinical investigators with not only a critical survey of the rapidly expanding research in the area, but also a state-of-the-art tutorial on today's optimal assessment and treatment of bladder cancer.

This issue of the Medical Clinics of North America is a comprehensive monograph on urology for the internist.? Topics covered include bladder pain syndrome; prostatitis and chronic pelvic pain syndrome; prostatism and lower urinary tract obstruction; neurologic/obstructive voiding dysfunction; neurologic/obstructive voiding dysfunction; irritative voiding symptoms; HIV/AIDS and STDs of the urinary tract; hematuria; renal mass; decreasing renal function; urologic stone disease; PSA in prostate cancer; erectile dysfunction; male factor assessment in infertility; testicular mass; urologic trauma; and urinary frequency and incontinence.? Unique urologic issues for women, men, and children are discussed.

Geometric constraint programming increases flexibility in CAD design specifications and leads to new conceptual design paradigms.
This volume features a collection of work by leading researchers developing the various aspects of constraint-based product modeling.
In an introductory chapter the role of constraints in CAD systems of the future and their implications for the STEP data exchange format are discussed. The main part of the book deals with the application of constraints to conceptual and collaborative design, as well as state-of-the-art mathematical and algorithmic methods for constraint solving.