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The B7-CD28 family molecules are probably the most intensively
studied receptor-ligand systems in the field of immunology. This is
evident from the explosive accumulation of literature, particularly
in the last ten years. Recent years have witnessed rapid
discoveries and characterization of new receptors and ligands in
the family. These new pathways, although still in their infancy,
have already brought much excitement to the field. However, until
now, there has been no single volume to cover this entire area.
This book was created to bring together state-of-the-art
information and critical thinking from the leading investigators.
This book covers significant territory of this rapidly moving field
from structural biology and biochemical signalling to immunological
functions and their potential applications in the treatment of
human diseases. This is an excellent handbook and reference for
immunologists, health professionals as well as medical students and
graduate students in life science field.
The most practical and clinical reasons for attempting to
understand the immunology of infections and disease revolves around
the CD137 and CD137/41BB receptor and ligand molecules. This book
covers all aspects of CD137/4-1BB pathway research from
microbiology, infectious disease, molecular biology, biochemistry,
and genetics to immune responses and potential applications in the
diagnosis and treatment of human diseases. This pathway is emerging
as one of the most important targets for manipulation of immune
responses for disease diagnosis and treatment. This book is written
by the man who discovered the CD-137 and B7H1 molecules in
1999.
The most practical and clinical reasons for attempting to
understand the immunology of infections and disease revolves around
the CD137 and CD137/41BB receptor and ligand molecules. This book
covers all aspects of CD137/4-1BB pathway research from
microbiology, infectious disease, molecular biology, biochemistry,
and genetics to immune responses and potential applications in the
diagnosis and treatment of human diseases. This pathway is emerging
as one of the most important targets for manipulation of immune
responses for disease diagnosis and treatment. This book is written
by the man who discovered the CD-137 and B7H1 molecules in 1999.
The B7-CD28 family molecules are probably the most intensively
studied receptor-ligand systems in the field of immunology. This is
evident from the explosive accumulation of literature, particularly
in the last ten years. Recent years have witnessed rapid
discoveries and characterization of new receptors and ligands in
the family. These new pathways, although still in their infancy,
have already brought much excitement to the field. However, until
now, there has been no single volume to cover this entire area.
This book was created to bring together state-of-the-art
information and critical thinking from the leading investigators.
This book covers significant territory of this rapidly moving field
from structural biology and biochemical signalling to immunological
functions and their potential applications in the treatment of
human diseases. This is an excellent handbook and reference for
immunologists, health professionals as well as medical students and
graduate students in life science field.
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