The most practical and clinical reasons for attempting to
understand the immunology of infections and disease revolves around
the CD137 and CD137/41BB receptor and ligand molecules. This book
covers all aspects of CD137/4-1BB pathway research from
microbiology, infectious disease, molecular biology, biochemistry,
and genetics to immune responses and potential applications in the
diagnosis and treatment of human diseases. This pathway is emerging
as one of the most important targets for manipulation of immune
responses for disease diagnosis and treatment. This book is written
by the man who discovered the CD-137 and B7H1 molecules in
1999.
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