Samantha is stamped with a 'bipolar' label that becomes the trajectory for her tortured existence. For the next three decades she will wind through a maze of anguished suffering, accompanied by memory-effacing medical interventions in the form of electroconvulsive therapies, heaps of pills and repellent hallucinations. As her helpless family and loved ones watch, often in terror, Samantha yo-yos between acceptance and denial of her diagnosis. Time and again believing she is well, she plummets into the devastating chasm of her illness.

Life Interrupted is a deeply compelling memoir that brilliantly humanises the sufferer beyond the label. It is groundbreaking in the way the author shares the horrors of psychosis and unbounded mania, the fears of depression and the emergence of recovery.

This book will not only appeal to the over four million people diagnosed with bipolar in South Africa, but to the millions of people who are affected by loved ones with bipolar, as well as to everyone who reads it.

Die oorlewingstog van 'n dapper vrou.

“ ʼn Kale vlakte waar my regterbors eens was. Ek maak my oë toe en laat my brein toe om te proe aan hierdie monumentale ding. Kanker schmanker, besluit ek. Ek is nog net soveel vrou soos voor die operasie. My vroulikheid het toe al die tyd nie in my bors gesit nie. Dit sit in my kop, in my hart, in daardie onmeetbare, onaantasbare iets wat die gees genoem word.”

In hierdie aangrypende boek deel die bekende spanningsverhaalskrywer Madelein Rust die intiemste besonderhede van haar reis met borskanker. Dit is ʼn brutaal eerlike vertelling wat haar belewenis van die siekte met patos en humor uitbeeld. Lesers verkry ʼn eiesoortige blik op die fisieke ervarings van borskankerstryders sowel as die ewig veranderende binnewêreld van dié wat teen die siekte veg.

Kanker schmanker! rus borskankerstryders toe met inligting wat nie altyd geredelik beskikbaar is nie en help hul geliefdes om die reis met kanker beter te verstaan. Dit is ʼn boek van hoop en triomf wat die leser hardop laat huil en laat lag. Dis 'n verhaal vir elkeen van ons wat ʼn stryd van enige aard stry.

Since the first edition of HIV and AIDS Education, Care and Counselling was published almost 20 years ago, it has become the standard handbook in Africa for thousands of HIV and AIDS practitioners. However, ongoing HIV and AIDS research requires regular revisions to the handbook for it to remain current with developments in prevention and treatment. Consequently, this new edition has been updated with input from two new specialist co-authors. This has strengthened the multicultural and multidisciplinary approach of this edition to Africa's unique challenges.

Handbook of HIV Medicine represents the knowledge, skill and experience of more than sixty experts in HIV medicine, making it the definitive reference book for southern Africa.

This third edition remains invaluable for doctors, medical students, and primary health care workers, presenting an updated approach to critical issues. It is ideal for quick reference in urban and rural clinics and hospital wards.

The handbook is targeted specifically at the needs of the developing world and contains guidelines on antiretroviral therapy, HIV emergencies, and adult and paediatric HIV medicine.

Navigating motherhood from the age of 18, Kim Stephens shelved her inner journo and embraced a life of media sales and sports marketing, working with some of the biggest sports brands globally, and locally, whilst pursuing her own ultra-running ambitions.

Arguing vehemently against the possibility that she was running from her own truth, Covid-19 wiped out Kim’s possibilities for continued escape. After three children, two divorces and a gradual sexual awakening, Kim found herself at 40-something virtually unemployed, with all the time in the world to write, sip gin and study a general response to one of the world’s most draconian lockdowns. Her humorous observations of middle-class South African behaviour through the various levels of lockdown earned her a certain notoriety and a degree of viral success, and with that the courage to put it all into a book.

Hold the Line tells the story of teenage pregnancy, the situational blindness of white South Africa, the disappointment of divorce and the deep joy found through true awakening. Stitched together with the lockdown writing that Kim penned for a growing base of followers, she shares a more in-depth life story with her usual candid self-deprecation.

Written to rattle a few truths from within its readers, Hold the Line ends ironically as the world begins to follow a potential third World War via TikTok.

Walkley Award-winning journalist, Sharri Markson is the Investigations Editor at The Australian and host of prime-time show Sharri on Sky News Australia.

The origins of Covid-19 are shrouded in mystery. Scientists and government officials insisted, for a year and a half, that the virus had a natural origin, ridiculing anyone who dared contradict this view. Tech giants swept the internet, censoring and silencing debate in the most extreme fashion. Yet it is undeniable that a secretive facility in Wuhan was immersed in genetically manipulating bat-coronaviruses in perilous experiments. And as soon as the news of an outbreak in Wuhan leaked, the Chinese military took control and gagged all laboratory insiders.

Part-thriller, part-expose, What Really Happened in Wuhan is a ground-breaking investigation from leading journalist Sharri Markson into the origins of Covid-19, the cover-ups, the conspiracies and the classified research. It features never-before-seen primary documents exposing China's concealment of the virus, fresh interviews with whistleblower doctors in Wuhan and crucial eyewitness accounts that dismantle what we thought we knew about when the outbreak hit.

With unprecedented access to Washington insiders, Markson takes you inside the White House, with senior Trump lieutenants revealing first-hand accounts of fiery Oval Office clashes and new stories of compromised government advisors and censored scientists.

Bravely reported and chillingly laid out, Markson brings to light the stories of the pandemic from the people on the ground: the scientists and national security officials who raised uncomfortable truths and were labelled conspiracy theorists, until government agencies began to suspect they might have been right all along. These brave individuals persisted through bruising battles and played a crucial role in investigating the origins of Covid-19 to finally, in this book, bring us closer to the truth of what really happened in Wuhan.

For those who could read between the lines, the censored news out of China was terrifying. But the president insisted there was nothing to worry about. Fortunately, we are still a nation of skeptics. Fortunately, there are those among us who study pandemics and are willing to look unflinchingly at worst-case scenarios.

Michael Lewis’s taut and brilliant nonfiction thriller pits a band of medical visionaries against the wall of ignorance that was the official response of the Trump administration to the outbreak of COVID-19. The characters you will meet in these pages are as fascinating as they are unexpected.

A thirteen-year-old girl’s science project on transmission of an airborne pathogen develops into a very grown-up model of disease control. A local public-health officer uses her worm’s-eye view to see what the CDC misses, and reveals great truths about American society. A secret team of dissenting doctors, nicknamed the Wolverines, has everything necessary to fight the pandemic: brilliant backgrounds, world-class labs, prior experience with the pandemic scares of bird flu and swine flu…everything, that is, except official permission to implement their work.

Michael Lewis is not shy about calling these people heroes for their refusal to follow directives that they know to be based on misinformation and bad science. Even the internet, as crucial as it is to their exchange of ideas, poses a risk to them. They never know for sure who else might be listening in.

Where is South Africa going now? And where will South Africa be in five years’ time? Much has been written about the country’s past, but is enough thought being given to its future? Is South Africa in danger of again losing its way, given its pressing socio-economic challenges?

Prominent economist Raymond Parsons has drawn together a powerful collection of expert thinkers, economists and analysts who tackle these issues head on as well as offering timely solutions to several of South Africa’s most pressing problems, drawing key lessons from the past in crystallising what South Africa needs to do to create a better future.

After the so-called ‘lost decade’ under the Zuma administration, South Africans had high hopes that President Ramaphosa would deliver on his promise of a ‘new dawn’. Yet despite high expectations that the country would finally turn the corner and settle onto a path of stronger inclusive growth and better governance, socioeconomic conditions have deterioriated. Growth remains negligible, unemployment has worsened and the fiscus is under considerable strain. Will SA be able to break out of its present ‘growth trap’ without falling into a ‘debt trap’?

The country is also facing global headwinds in the form of volatile market conditions, shifting geopolitics, and a fast-changing and disruptive technological landscape which threatens to leave all but the most well-prepared behind. So how must the different strands of policy – ranging from purely economic issues to broader questions around education and the rule of law – now knit together to create a bigger, stronger and better SA economy in future?

If the vision of a well-functioning society is to be realised, policy uncertainty about the road ahead must be generally tackled at the highest level to facilitate job-rich growth. And business and civil society, in its turn, must take a long-term view of South Africa’s future and commit energy and resources to bringing about change which is both productive and transformational.

Recession, Recovery & Reform will offer compelling new insights into how South Africa can unlock its potential in the years ahead. The publication of this title a month ahead of the ANC policy conference in June 2020, at which President Ramaphosa’s political and economic ‘track record’ will be widely assessed, ensures it will be a must-read for all who are concerned about South Africa’s well-being and who are willing to believe that a ‘new dawn’ is indeed possible.

When Lauren Segal receives a call from her husband one wintry morning in 2014, the furthest thing from her mind is her biopsy results. For two years she’s been living a cancer-free existence after a double mastectomy that has put her in the clear. The call shatters the foundation of her world – the lump she thought was scar tissue is malignant. Her cancer is back.

Cancer: A Love Story is the intimately searing memoir of a four-time cancer survivor. The book magnificently tracks Lauren’s journey to come to terms with the untold challenges of facing the dreaded disease. Forced to face her needle phobia, the author leads the reader into her crumbling world as she confronts the terrors of treatment – from debilitating chemo to nuking radiation. Death is her uninvited companion.

But in the midst of her lonely horror, in a quest for deeper meaning, Lauren discovers the unexpected gift of awareness of unanticipated opportunities that cancer presents – to confront her unmasked humanity – her fears, strengths and weaknesses.

“Throughout my arduous journey into the world of cancer, I have discovered that proximity to death brings with it a new proximity to life. I have learned that luck and unluck, happiness and distress, hope and despair are tightly coiled into a life well lived.” Lauren’s story removes the enormous stigma that still surrounds breast cancer; it tackles the deep fear surrounding diagnoses and treatment and it encourages us to take control of our health. It ultimately triumphs by showing the reader how a person in any unwanted life situation can come out on the other side. The book also provides vital insights for professionals involved in the care of cancer patients and a hugely informative section on chemo tips for those undergoing treatment.

As late as the 1980s, breast cancer was a stigmatized disease, so much so that local reporters avoided using the word "breast" in their stories and early breast cancer organizations steered clear of it in their names. But activists with business backgrounds began to partner with corporations for sponsored runs and cause-marketing products, from which a portion of the proceeds would benefit breast cancer research. Branding breast cancer as "pink"-hopeful, positive, uncontroversial-on the products Americans see every day, these activists and corporations generated a pervasive understanding of breast cancer that is widely shared by the public and embraced by policymakers. Clearly, they have been successful: today, more Americans know that the pink ribbon is the symbol of breast cancer than know the name of the vice president. Hiding Politics in Plain Sight examines the costs of employing market mechanisms-especially cause marketing-as a strategy for change. Patricia Strach suggests that market mechanisms do more than raise awareness of issues or money to support charities: they also affect politics. She shows that market mechanisms, like corporate-sponsored walks or cause-marketing, shift issue definition away from the contentious processes in the political sphere to the market, where advertising campaigns portray complex issues along a single dimension with a simple solution: breast cancer research will find a cure and Americans can participate easily by purchasing specially-marked products. This market competition privileges even more specialized actors with connections to business. As well, cooperative market activism fundamentally alters the public sphere by importing processes, values, and biases of market-based action into politics. Market activism does not just bring social concerns into market transactions, it also brings market biases into public policymaking, which is inherently undemocratic. As a result, industry and key activists work cooperatively rather than contentiously, and they define issues as consensual rather than controversial, essentially hiding politics in plain sight.

Ook in Engels beskikbaar: Knowledge Beats Cancer
JY HET KANKER! 'n Ystervuis beklem jou hart wanneer jy die diagnose hoor. Ná die skok en ontkenning kom die vrae: Wat gaan nou met my gebeur? Wat is my oorlewingskans?
In Kennis Klop Kanker word die pasiënt, en enigeen wat meer van kanker wil weet, ingelig oor alle fasette van kanker:
Wat kanker presies is en hoe kanker ontstaan
Die omvangsyfer en suksesse van kankerterapieë
Belangrikheid van dieet, noodsaaklike gereelde ondersoeke en selfondersoeke
Die vele vertakkinge en benaderinge van moderne terapieë
Moderne behandelingsmetodes en prognose van algemene kankers (29 tipes)
Deurbrake in molekulêre biologie met minder newe-effekte
Beenmurgstamseloorplanting
Mediane oorlewingstatistiek
Alternatiewe, komplementerende en integrerende terapieë
Pasiëntondersteuning, herstel ná mastektomie, kanker by jongmense en kinders, goeie pynkontrole, versorging van pasiënte met gevorderde kanker
Ondersteuning deur gemeenskapsorganisasies
Skrywer se persoonlike perspektief oor lyding en geloofsgenesing
DIE OUTEUR: Albert Stegmann Alberts is 'n onkoloog wat 33 jaar lank met kankerpasiënte gewerk het. Hy het gespesialiseer in al die vertakkings van kankerterapie. Hy is die outeur van verskeie internasionale publikasies.

Remarkable advances have occurred since the Series 3 Fascicle published in 1995 with paradigm shifts in every dimension of our understanding of lung tumors including clinical, radiologic, histopathologic, cytopathologic, immunohistochemical, molecular and therapeutic aspects. The molecular revolution leading to effective targeted therapies and breakthroughs in immunotherapy for lung cancer have led to novel approaches incorporating the concept of personalized medicine for patients who historically had little hope. These advances have strengthened the place of pathologists to play a central role in the multidisciplinary team that is now needed to properly diagnose and manage lung cancer patients.

The onset of the quadruple burden of disease in South Africa, the challenges faced by the medical establishment to curtail the rapid growth of multiple epidemics, the inadequate response by the state to various inequities in the health system, and the public debates associated with it, have all combined to draw attention to the sociological aspects of health and disease. Sociology as a resource of knowledge and a unique analytical and conceptual perspective can be used to understand, explain and positively influence the course of health and disease in South African society and our responses to it. As a health practitioner or scholar you must be equipped with the skills to critically evaluate research and debates in your profession, be able to adapt to changes and contribute to the development of knowledge and best practice. This reader will familiarise you with relevant content and assist you to develop the analytical capacity and conceptual skills you will need. Society, Health and Disease in South Africa is authored by experienced educators and researchers in the fi elds of sociology, social work, anthropology, healthcare policy and practice.

After her diagnosis of triple negative breast cancer (TNBC), health journalist Patricia Prijatel did what any reporter would do: start investigating the disease, how it occurs, and how it's treated. While she learned that important research was emerging, she found a noticeable lack of resources on the disease, which affects 70,000 women a year and differs from hormone-positive breast cancer in important ways, including prognosis and treatment options. Hormone negative breast cancer disproportionately affects younger women and African-American women - and it can be more dangerous than other types of breast cancer. But there are many reasons to be hopeful, as Prijatel learned. Through her blog, Positives About Negative, she has met hundreds of women who have told her their stories and shared their fears, confusion, and frustration. After her recovery, she began writing this book to provide the first dedicated resource for women diagnosed with TNBC. Surviving Triple Negative Breast Cancer delivers research-based information on the biology of TNBC; the role of genetics, family history, and race; how to navigate treatment options; and a plethora of strategies to reduce the risk of recurrence, including diet and lifestyle changes. In clear, approachable language, Prijatel provides an accessible guide to understanding a pathology report and a vast array of scientific studies. Woven throughout the book are stories of women who have faced TNBC. These are mothers, wives, daughters, and sisters who went through a variety of medical treatments and then got on with life - one competes in triathlons, two had babies after being treated with chemo, one got remarried in her 50s, and one just celebrated the 30th birthday of the son she was nursing when she was diagnosed. With honesty and humor, Prijatel's inspiring story shows the heart of a survivor. Her message is that TNBC is a disease to take seriously, with proper and occasionally aggressive treatment, but it is not automatically a killer. Most women diagnosed with the disease do survive. Surviving Triple Negative Breast Cancer is a roadmap for women who want to be empowered through their treatment and recovery.

Cancer is diagnosed in about 140 per million children in Britain each year. There is a 1 in 500 chance that a child will be affected in the first 15 years of life, the most frequently occurring types of cancer being leukaemia and brain tumours. This book covers the descriptive epidemiology of childhood cancer in Britain, based on the unique work of the National Registry of Childhood Tumours, the largest population-based specialist childhood cancer registry in the world. The book provides a detailed account of national incidence and survival rates for childhood cancer in Britain during 1991-2000, and trends during 1966-2000. There is also an account of childhood mortality for the period 1965-2004. The diagnoses are classified throughout according to the International Classification of Childhood Cancer, the first time the third edition of this standard classification has been used for prevalence of incidence, survival and mortality data. The chapter on incidence rates is relevant to planning of health service provision and design of research studies on aetiology, whilst the chapter on trends in incidence is relevant to the possible effects of changes in environmental and other risk factors. In addition to comprehensive tables of rates, age-incidence graphs are provided for all the major types of childhood cancer, and possible artefacts are also discussed. The survival data demonstrates how clinical progress over the past 40 years has led to a major increase in the number of cancer survivors. The role of the Registry, covering history, methodology, current and future uses, is also discussed. This definitive work is the culmination of decades of epidemiological research and is essential reading for anyone involved in paediatric oncology or cancer epidemiology.

The Culture of AIDS in Africa enters into the many worlds of expression brought forth across this vast continent by the ravaging presence of HIV/AIDS. Africans and non-Africans, physicians and social scientists, journalists and documentarians share here a common and essential interest in understanding creative expression in crushing and uncertain times. They investigate and engage the social networks, power relationships, and cultural structures that enable the arts to convey messages of hope and healing, and of knowledge and good counsel to the wider community. And from Africa to the wider world, they bring intimate, inspiring portraits of the performers, artists, communities, and organizations that have shared with them their insights and the sense they have made of their lives and actions from deep within this devastating epidemic.
Covering the wide expanse of the African continent, the 30 chapters include explorations of, for example, the use of music to cope with AIDS; the relationship between music, HIV/AIDS, and social change; visual approaches to HIV literacy; radio and television as tools for "edutainment;" several individual artists' confrontations with HIV/AIDS; various performance groups' response to the epidemic; combating HIV/AIDS with local cultural performance; and more. Source material, such as song lyrics and interviews, weaves throughout the collection, and contributions by editors Gregory Baz and Judah M. Cohen bookend the whole, to bring together a vast array of perspectives and sources into a nuanced and profoundly affective portrayal of the intricate relationship between HIV/AIDS and the arts in Africa.

The Motoneurone and its Muscle Fibres presents a state-of-the-art summary of knowledge concerning the motoneurones, vital for innervating and commanding skeletal muscles. No muscle action would be possible without motoneurones. These cells are therefore absolutely essential for the execution of normal behaviour and for life support. It is their degeneration that leads to various kinds of motoneurone disease (e.g. ALS) that are often ultimately lethal. However, the study of motoneurones is also important for general insights as to how neurones work, because the motoneurone is probably the best understood kind of nerve cell so far in neuroscience. Motoneurones of the spinal cord were the first type of central nerve cell to be subjected to detailed physiological measurements, and much is known about how their activity is regulated by synapses from other central neurones. For most of the individual neurones within the central nervous system, the precise functional tasks are difficult to define. However, for motoneurones much is now known about their short- and long-term interactions with their main targets, the skeletal muscle fibres. Functions of neurones must be analyzed in relation to the response properties of their target cells. Therefore, this book deals with both, summarizing classical as well as recent knowledge concerning the motoneurone and its muscle fibres. This is the first time that so many aspects of this broad subject matter are treated in one comprehensive monograph.

The role of parasites and pathogens in the evolution of life history traits is of increasing interest to both ecologists and evolutionary biologists. Immunology, which was once studied almost exclusively by immunologists, has become an important area of proximate investigation to animal physiologists as a means for understanding changes in disease susceptibility and the neural and neuroendocrine mechanisms that mediate these changes. The coalescence of these different perspectives has given rise to the field of ecological immunology, an interdisciplinary research field that examines interactions among host physiology and disease ecology in a wide range of environmentally relevant contexts. The goal of ecological immunology is to understand immune function in the context of life-history traits across a wide range of organisms. Research within the field combines diverse approaches from a wide range of scientific disciplines including evolution, ecology, and life history theory to endocrinology, neuroscience, molecular biology, and behavior. This book critically reviews recent advances in the discipline of ecoimmunology. Chapters are written by experts in their respective fields and cover diverse topics including how environmental factors can affect host immune function, the complex dynamics among host immunity, pathogen prevalence and disease susceptibility, and the physiological mechanisms that lead to adaptive changes in immune responses. By integrating analyses of immune system function within animal biology, investigators will gain will gain a more comprehensive and satisfying understanding of organism-environment interactions at both ultimate and proximate levels of analysis.

How does a pathologist become interested and develop expertise in testicular and paratesticular neoplasms, which are relatively uncommon? The truth is simple-the opportunity to see many cases. The authors of this 5th Series Fascicle have such expertise and share a remarkable range of cases from their institutions as well as from many pathologists throughout the world who have sent them cases in consultation over the years. This fascicle is rich source of material that will be a great resource for practicing pathologists and pathologists in training.

As the coronavirus pandemic swept across the globe in recent months, many countries have had to implement strategies to fight the virus and keep its people safe. These strategies, particularly in the West, have not been as effective at keeping the numbers of infected people as low as the governments would have hoped.

Charles R Stith predicted the trajectory the virus would take as its spread progressed and developed a critical analysis of the western countries’ responses to the pandemic. He specifically focuses on South Africa’s response to the virus as it spearheads the surge of cases on the African continent.

The crisis has far reaching consequences that impacts the most vulnerable people in the country. A recent OXFAM report draws connections between the lockdown, to hunger, to deaths which confirms the statement Stith made at the beginning of the outbreak about how people would die of hunger as they lose their jobs, their ability to provide for their families and access to fresh foods.

Stith wrote this book in real time in response to the growth and spread of the coronavirus and analyses the results of South Africa’s response to it. He gives answers to the questions politicians should have been asking and gives his view of what Africa will require to recover