Tending Adam's Garden describes and explains the way in which our immune system works from a novel perspective. The book uses metaphors and examples to bring the immune system to life and explores the fundamental miracle of nature. Written in plain language for a broad audience, this book encompasses much more than just immunology, exploring more fundamental matters such as causality, information, energy, evolution, cognition and individuality, as well as the strategy of the immune system and its role in health and disease.
* Provides a unique perspective on the immune system from one of the keenest scientific and philosophical brains in the world
* Uses metaphors and case histories to explore themes in an accessible manner
* Written in plain language requiring no specialized vocabulary or specific scientific background in the subject

All those involved in maternity care need to be aware of the issues women face when considering HIV and pregnancy. Since the first reported cases of AIDS two decades ago there has been much research into the HIV virus, and attitudes have changed as knowledge has increased. Today, a much better understanding of HIV and related AIDS conditions has enabled the midwife to apply evidence-based guidelines to everyday practice. It is essential that midwives are aware of the most up-to-date research findings so that they can ensure they offer their clients the best possible care during pregnancy and childbirth. HIV in Pregnancy and Childbirth takes a comprehensive look at the subject in a practical manner, covering epidemiology, transmission, the disease progress and the provision of holistic pregnancy care. Fully referenced with useful appendices and website addresses, this is an essential purchase for all healthcare professionals.An exploration of the latest research into the HIV virus focussing on issues specifically relevant to pregnant women and the newborn Written by a midwife who specialises in counselling HIV-positive women, this book deals with the issues midwives are most likely to encounter in practice Discusses the latest findings on breastfeeding and routes of transmission of the virus Includes guidelines and recommendations for the management of infected healthcare workers

This book provides a detailed overview of cancer theranostics applications of magnetic iron oxide nanoparticles. Their synthesis, characterization, multifunctionality, disease targeting, biodistribution, pharmacokinetics and toxicity are highlighted, along with current examples of clinical trials of magnetic nanoparticles in cancer theranostics, and their future scopes and challenges.

Advances in Cancer Research provides invaluable information on the exciting and fast-moving field of cancer research. Here, once again, outstanding and original reviews are presented on a variety of topics, including platelet-derived growth factor in disease, genetic predisposition in tumor development, primary effusion lymphoma, and many more.
Cancer is not one disease, but a group of diseases in which malignant cells grow out of control and spread to other parts of the body. Eventually these cells form a visible mass or tumor. Appropriate treatment for cancer depends on what kind of cancer a person has. The type of cancer is determined by the organ the cancer starts in, the kind of cell from which it is derived, and the appearance of the cancer cells.

Advances in Immunology presents current developments as well as comprehensive reviews in immunology. Articles address the wide range of topics that constitue immunology, including molecular and cellular activation mechanisms, phylogeny and molecular evolution, and clinical modalities. Edited and authored by the foremost scientists in the field, each volume provides up-to-date information and directions for future research.
Immunology is vital to the understanding of infection and disease. Application of this information may lead to resistance and cures for higher animals and humans.

This is the most comprehensive review of the idiotypic network available. All the current knowledge of idiotypes of the various antibodies is incorporated in this volume. The pathogenic role of idiotypes in autoimmunity and cancer is reviewed in depth. The therapeutic part focusses on harnessing anti-idiotypes for treating autoimmunological disorders, and on the employment of idiotypes for vaccines in cancer and infectious diseases, as well as explaining the manipulation of the idiotypic network in autoimmunity and cancer idiotypes and vaccines.

In the late 1980s, a promising new treatment for breast cancer emerged: high-dose chemotherapy with autologous bone marrow transplantation or HDC/ABMT. By the 1990s, it had burst upon the oncology scene and disseminated rapidly before having been carefully evaluated. By the time published studies showed that the procedure was ineffective, more than 30,000 women had received the treatment, shortening their lives and adding to their suffering. This book tells of the rise and demise of HDC/ABMT for metastatic and early stage breast cancer, and fully explores the story's implications, which go well beyond the immediate procedure, and beyond breast cancer, to how we in the United States evaluate other medical procedures, especially life-saving ones.
It details how the factors that drove clinical use--patient demand, physician enthusiasm, media reporting, litigation, economic exploitation, and legislative and administrative mandates--converged to propel the procedure forward despite a lack of proven clinical effectiveness. It also analyzes the limited effect of technology assessments before randomized clinical trials evaluated decisively the procedure and the ramifications of this system on healthcare today.
Sections of the book consider the initial conditions surrounding the emergence of the new breast cancer treatment, the drivers of clinical use, and the struggle for evidence-based medicine. A concluding section considers the significance of the story for our healthcare system.

After her diagnosis of triple negative breast cancer (TNBC), health journalist Patricia Prijatel did what any reporter would do: start investigating the disease, how it occurs, and how it's treated. While she learned that important research was emerging, she found a noticeable lack of resources on the disease, which affects 70,000 women a year and differs from hormone-positive breast cancer in important ways, including prognosis and treatment options. Hormone negative breast cancer disproportionately affects younger women and African-American women - and it can be more dangerous than other types of breast cancer. But there are many reasons to be hopeful, as Prijatel learned. Through her blog, Positives About Negative, she has met hundreds of women who have told her their stories and shared their fears, confusion, and frustration. After her recovery, she began writing this book to provide the first dedicated resource for women diagnosed with TNBC. Surviving Triple Negative Breast Cancer delivers research-based information on the biology of TNBC; the role of genetics, family history, and race; how to navigate treatment options; and a plethora of strategies to reduce the risk of recurrence, including diet and lifestyle changes. In clear, approachable language, Prijatel provides an accessible guide to understanding a pathology report and a vast array of scientific studies. Woven throughout the book are stories of women who have faced TNBC. These are mothers, wives, daughters, and sisters who went through a variety of medical treatments and then got on with life - one competes in triathlons, two had babies after being treated with chemo, one got remarried in her 50s, and one just celebrated the 30th birthday of the son she was nursing when she was diagnosed. With honesty and humor, Prijatel's inspiring story shows the heart of a survivor. Her message is that TNBC is a disease to take seriously, with proper and occasionally aggressive treatment, but it is not automatically a killer. Most women diagnosed with the disease do survive. Surviving Triple Negative Breast Cancer is a roadmap for women who want to be empowered through their treatment and recovery.

Navigating motherhood from the age of 18, Kim Stephens shelved her inner journo and embraced a life of media sales and sports marketing, working with some of the biggest sports brands globally, and locally, whilst pursuing her own ultra-running ambitions.

Arguing vehemently against the possibility that she was running from her own truth, Covid-19 wiped out Kim’s possibilities for continued escape. After three children, two divorces and a gradual sexual awakening, Kim found herself at 40-something virtually unemployed, with all the time in the world to write, sip gin and study a general response to one of the world’s most draconian lockdowns. Her humorous observations of middle-class South African behaviour through the various levels of lockdown earned her a certain notoriety and a degree of viral success, and with that the courage to put it all into a book.

Hold the Line tells the story of teenage pregnancy, the situational blindness of white South Africa, the disappointment of divorce and the deep joy found through true awakening. Stitched together with the lockdown writing that Kim penned for a growing base of followers, she shares a more in-depth life story with her usual candid self-deprecation.

Written to rattle a few truths from within its readers, Hold the Line ends ironically as the world begins to follow a potential third World War via TikTok.

Juta’s Communicable Diseases offers students and health practitioners an up-to-date and concise guide on communicable diseases, including COVID-19, monkey pox and the zika virus. The content includes legal and ethical obligations; myths and misunderstandings about communicable diseases; immunisation and vaccination, reporting of communicable diseases; epidemiology; response to outbreaks, and prevention and management of communicable diseases. The diseases are systematically grouped by their main means of transmission.

The Culture of AIDS in Africa enters into the many worlds of expression brought forth across this vast continent by the ravaging presence of HIV/AIDS. Africans and non-Africans, physicians and social scientists, journalists and documentarians share here a common and essential interest in understanding creative expression in crushing and uncertain times. They investigate and engage the social networks, power relationships, and cultural structures that enable the arts to convey messages of hope and healing, and of knowledge and good counsel to the wider community. And from Africa to the wider world, they bring intimate, inspiring portraits of the performers, artists, communities, and organizations that have shared with them their insights and the sense they have made of their lives and actions from deep within this devastating epidemic.
Covering the wide expanse of the African continent, the 30 chapters include explorations of, for example, the use of music to cope with AIDS; the relationship between music, HIV/AIDS, and social change; visual approaches to HIV literacy; radio and television as tools for "edutainment;" several individual artists' confrontations with HIV/AIDS; various performance groups' response to the epidemic; combating HIV/AIDS with local cultural performance; and more. Source material, such as song lyrics and interviews, weaves throughout the collection, and contributions by editors Gregory Baz and Judah M. Cohen bookend the whole, to bring together a vast array of perspectives and sources into a nuanced and profoundly affective portrayal of the intricate relationship between HIV/AIDS and the arts in Africa.

When the first edition of this book published in 1994, the psychoimmunology of cancer was still emerging as a topic for serious scientific study. Now, less than ten years later, there is a huge quantity of academic literature about the relationships between psychological variables, the immune system and cancer growth, accompanied by a lively popular interest.

In this new edition leading specialists have provided broad critical reviews of the different aspects. Part I, which presents the biological background, will be of particular interest to those with technical knowledge of the relevant laboratory based disciplines. It covers mechanisms mediating the effects of psychological status in the immune system, and anti-cancer mechanisms involving the immune system. Part II is clinically orientated, and accessible to a wide audience. Whether psychotherapeutic interventions can help patients live longer, as well as coping better, is obviously the key question and several contributors consider the clinical evidence for this. A new, speculative chapter on the spiritual context of immunity and cancer has also been added.

The psychoimmunology of cancer involves many complex issues, understanding of which remains far from complete. However, the contributors, besides reviewing the current state of knowledge and the implications for cancer patients, offer predictions for the future and ideas about further research.

From reviews of the first edition:

'The chief quality of this book is its presentation of an excellent but critical overview of the entire range of what is today called 'psychoimmunology', and it is to be recommended to all who are interested in the subject.' Annals of Oncology

The role of parasites and pathogens in the evolution of life history traits is of increasing interest to both ecologists and evolutionary biologists. Immunology, which was once studied almost exclusively by immunologists, has become an important area of proximate investigation to animal physiologists as a means for understanding changes in disease susceptibility and the neural and neuroendocrine mechanisms that mediate these changes. The coalescence of these different perspectives has given rise to the field of ecological immunology, an interdisciplinary research field that examines interactions among host physiology and disease ecology in a wide range of environmentally relevant contexts. The goal of ecological immunology is to understand immune function in the context of life-history traits across a wide range of organisms. Research within the field combines diverse approaches from a wide range of scientific disciplines including evolution, ecology, and life history theory to endocrinology, neuroscience, molecular biology, and behavior. This book critically reviews recent advances in the discipline of ecoimmunology. Chapters are written by experts in their respective fields and cover diverse topics including how environmental factors can affect host immune function, the complex dynamics among host immunity, pathogen prevalence and disease susceptibility, and the physiological mechanisms that lead to adaptive changes in immune responses. By integrating analyses of immune system function within animal biology, investigators will gain will gain a more comprehensive and satisfying understanding of organism-environment interactions at both ultimate and proximate levels of analysis.

THE SUNDAY TIMES BESTSELLER The inspirational memoir from the founder of the You, Me and the Big C podcast, Rachael Bland. Courageous and life-affirming, this is a mother’s final gift to her son. My beautiful son, I so wish that I didn’t have to leave you now. But believe me, I tried EVERYTHING I could to stay around for you, and for every moment I could eke out of this life. From the outset, it was not a fair fight. My cancer was too big, and too aggressive, and we didn’t start on a level playing field. You were fourteen months old and at the beginning I was so full of fierce intention that we could get past this. I would lay you in your cot each night and silently communicate from my mind to yours, ‘I will do this Freddie, I will gladly take whatever they throw at me if it means we can stay together’. In 2016, beloved broadcaster and journalist Rachael Bland was diagnosed with cancer. Shortly afterwards she made the brave decision to share her story, and she spoke with beautiful poignancy through her blog and podcast, You, Me and the Big C. Having been told that she only had a matter of months left to live and writing this in what were sadly her final days, Rachael brings her warmth, courage and humour to the page in this heart-warming and heart-breaking story. Part memoir, part advice, For Freddie beautifully encapsulates the grace and fearlessness in which Rachael lived her life. This is her legacy and an incredible final gift to her son. Includes moving contributions from Richard Bacon, Tony Livesey, Emma Barnett, Shelagh Fogarty, Mark Pougatch, Chris Stark and many more.

The onset of the quadruple burden of disease in South Africa, the challenges faced by the medical establishment to curtail the rapid growth of multiple epidemics, the inadequate response by the state to various inequities in the health system, and the public debates associated with it, have all combined to draw attention to the sociological aspects of health and disease. Sociology as a resource of knowledge and a unique analytical and conceptual perspective can be used to understand, explain and positively influence the course of health and disease in South African society and our responses to it. As a health practitioner or scholar you must be equipped with the skills to critically evaluate research and debates in your profession, be able to adapt to changes and contribute to the development of knowledge and best practice. This reader will familiarise you with relevant content and assist you to develop the analytical capacity and conceptual skills you will need. Society, Health and Disease in South Africa is authored by experienced educators and researchers in the fi elds of sociology, social work, anthropology, healthcare policy and practice.

Ook in Engels beskikbaar: Knowledge Beats Cancer
JY HET KANKER! 'n Ystervuis beklem jou hart wanneer jy die diagnose hoor. Ná die skok en ontkenning kom die vrae: Wat gaan nou met my gebeur? Wat is my oorlewingskans?
In Kennis Klop Kanker word die pasiënt, en enigeen wat meer van kanker wil weet, ingelig oor alle fasette van kanker:
Wat kanker presies is en hoe kanker ontstaan
Die omvangsyfer en suksesse van kankerterapieë
Belangrikheid van dieet, noodsaaklike gereelde ondersoeke en selfondersoeke
Die vele vertakkinge en benaderinge van moderne terapieë
Moderne behandelingsmetodes en prognose van algemene kankers (29 tipes)
Deurbrake in molekulêre biologie met minder newe-effekte
Beenmurgstamseloorplanting
Mediane oorlewingstatistiek
Alternatiewe, komplementerende en integrerende terapieë
Pasiëntondersteuning, herstel ná mastektomie, kanker by jongmense en kinders, goeie pynkontrole, versorging van pasiënte met gevorderde kanker
Ondersteuning deur gemeenskapsorganisasies
Skrywer se persoonlike perspektief oor lyding en geloofsgenesing
DIE OUTEUR: Albert Stegmann Alberts is 'n onkoloog wat 33 jaar lank met kankerpasiënte gewerk het. Hy het gespesialiseer in al die vertakkings van kankerterapie. Hy is die outeur van verskeie internasionale publikasies.