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The Motoneurone and its Muscle Fibres (Hardcover)
Loot Price: R4,415
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The Motoneurone and its Muscle Fibres (Hardcover)
Series: Monographs of the Physiological Society
Expected to ship within 12 - 17 working days
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The Motoneurone and its Muscle Fibres presents a state-of-the-art
summary of knowledge concerning the motoneurones, vital for
innervating and commanding skeletal muscles. No muscle action would
be possible without motoneurones. These cells are therefore
absolutely essential for the execution of normal behaviour and for
life support. It is their degeneration that leads to various kinds
of motoneurone disease (e.g. ALS) that are often ultimately lethal.
However, the study of motoneurones is also important for general
insights as to how neurones work, because the motoneurone is
probably the best understood kind of nerve cell so far in
neuroscience. Motoneurones of the spinal cord were the first type
of central nerve cell to be subjected to detailed physiological
measurements, and much is known about how their activity is
regulated by synapses from other central neurones. For most of the
individual neurones within the central nervous system, the precise
functional tasks are difficult to define. However, for motoneurones
much is now known about their short- and long-term interactions
with their main targets, the skeletal muscle fibres. Functions of
neurones must be analyzed in relation to the response properties of
their target cells. Therefore, this book deals with both,
summarizing classical as well as recent knowledge concerning the
motoneurone and its muscle fibres. This is the first time that so
many aspects of this broad subject matter are treated in one
comprehensive monograph.
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