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Books > Medicine > Clinical & internal medicine > Diseases & disorders > Immunology > General

Janeway's Immunobiology (Paperback, 9th New edition): Kenneth Murphy, Casey Weaver Janeway's Immunobiology (Paperback, 9th New edition)
Kenneth Murphy, Casey Weaver
R1,611 R1,529 Discovery Miles 15 290 Save R82 (5%) Shipped within 7 - 12 working days

Janeway's Immunobiology is a textbook for students studying immunology at the undergraduate, graduate, and medical school levels. As an introductory text, students will appreciate the book's clear writing and informative illustrations, while advanced students and working immunologists will value its comprehensive scope and depth. Janeway's Immunobiology presents immunology from a consistent point of view throughout-that of the host's interaction with an environment full of microbes and pathogens. The Ninth Edition has been thoroughly revised bringing the content up-to-date with significant developments in the field, especially on the topic of innate immunity, and improving the presentation of topics across chapters for better continuity.

The Compatibility Gene (Paperback): Daniel M. Davis The Compatibility Gene (Paperback)
Daniel M. Davis 1
R230 R157 Discovery Miles 1 570 Save R73 (32%) Shipped within 7 - 12 working days

Short-listed for the Society of Biology Book Award 2014 Long-listed for the Royal Society Winton prize for science books 2014 In The Compatibility Gene, leading scientist Daniel M Davis tells the story of the crucial genes that define our relationships, our health and our individuality. We each possess a similar set of around 25,000 human genes. Yet a tiny, distinctive cluster of these genes plays a disproportionately large part in how our bodies work. These few genes, argues Davis, hold the key to who we are as individuals and our relationship to the world: how we combat disease, how our brains are wired, how attractive we are, even how likely we are to reproduce. The Compatibility Gene follows the remarkable history of these genes' discovery. From the British scientific pioneers who struggled to understand the mysteries of transplants to the Swiss zoologist who devised a new method of assessing potential couples' compatibility based on the smell of worn T-shirts, Davis traces a true scientific revolution in our understanding of the human body: a global adventure spanning some sixty years. 'Unusual results, astonishing implications and ethical dilemmas' The Times 'Packed with an insider's knowledge' New York Times 'He makes immunology as fascinating to popular science readers as cosmology, consciousness, and evolution' Steven Pinker 'An elegantly written, unexpectedly gripping account' Bill Bryson Guardian, Books of the Year Daniel M Davis is director of research at the University of Manchester's Collaborative Centre for Inflammation Research and a visiting professor at Imperial College, London. He has published over 100 academic articles, including papers in Nature and Science, and Scientific American. He has won the Oxford University Press Science Writing Prize and given numerous interviews for national and international media. He was elected a Fellow of the Academy of Medical Sciences in 2011.

The Immune System (Paperback, 4th New edition): Peter Parham The Immune System (Paperback, 4th New edition)
Peter Parham 1
R1,473 R1,393 Discovery Miles 13 930 Save R80 (5%) Shipped within 7 - 12 working days

The Immune System, Fourth Edition emphasizes the human immune system and presents immunological concepts in a coherent, concise, and contemporary account of how the immune system works. Written for undergraduate, medical, veterinary, dental, and pharmacy students, it makes generous use of medical examples to illustrate points. This classroom-proven textbook offers clear writing, full-color illustrations, and section and chapter summaries that make the book accessible and easily understandable to students. The Fourth Edition is a major revision that brings the content up-to-date and improves clarity. Based on user feedback, there is now increased continuity and connectivity between chapters. The Immune System is additionally supported by the Garland Science Learning System. This homework platform is designed to evaluate and improve student performance and allows instructors to select assignments on specific topics and review the performance of the entire class, as well as individual students, via the instructor dashboard. Students receive immediate feedback on their mastery of the topics, and will be better prepared for lectures and classroom discussions. The user-friendly system provides a convenient way to engage students while assessing progress. Performance data can be used to tailor classroom discussion, activities, and lectures to address students' needs precisely and efficiently. For more information and sample material, visit http://garlandscience.rocketmix.com/. A free trial for the Garland Science Learning System will be available to use during the Fall 2016 and Spring 2017 semesters. Please contact us directly at [email protected] to sign up!

Into the Forest - How Trees Can Help You Find Health and Happiness (Paperback): Dr Qing Li Into the Forest - How Trees Can Help You Find Health and Happiness (Paperback)
Dr Qing Li 1
R215 R169 Discovery Miles 1 690 Save R46 (21%) Shipped within 4 - 8 working days

Humans are increasingly becoming an indoor species. We spend 90 per cent of our life indoors. And, on average, we dedicate eight hours a day looking at screens. Our increasingly domestic lives are having huge consequences to our health. In Into the Forest, Immunologist and Forest Medicine expert, Dr Qing Li, examines the unprecedented benefits of the world's largest natural health resource: the great outdoors. Applying cutting-edge research and emerging science, Dr Li explores the inherent connection between nature and improved wellbeing. This practical guide will help you overcome some of life's most problematic health issues, including how to: * reduce blood pressure; * lower stress; * improve energy levels; * and boost the immune system. From mindful strolls in your local park to listening to the wind, from watching the sunset to walking barefoot in the grass, Dr Li reveals the life-improving advantages of spending time around trees, for a healthier and happier you.

The Beautiful Cure - Harnessing Your Body's Natural Defences (Paperback): Daniel M. Davis The Beautiful Cure - Harnessing Your Body's Natural Defences (Paperback)
Daniel M. Davis 1
R215 R169 Discovery Miles 1 690 Save R46 (21%) Shipped within 4 - 8 working days

`Thrilling... Reads like the best kind of adventure story' STEPHEN FRY `Wonderful... recounts in exceptionally clear and sympathetic prose how research into the immune system has resulted in a health revolution' HENRY MARSH SHORTLISTED FOR THE ROYAL SOCIETY SCIENCE BOOK PRIZE A Best Book of the Year 2018 in The Times, Telegraph, New Scientist & Daily Mail Our immune system is one of the great marvels of nature - and it holds the key to human health. Here, Professor Daniel Davis charts the groundbreaking scientific quest to understand how it fights disease and enables the body to heal itself. He explains how it is affected by stress, sleep, age and our state of mind, and reveals how all of this knowledge is now unlocking a revolutionary approach to medicine and well-being. The Beautiful Cure tells a dramatic story of detective work and discovery, of puzzles solved and of the mysteries that remain, and of lives sacrificed and saved. `Thoroughly absorbing... Davis is a wonderful storyteller' BILL BRYSON

Case Studies in Immunology - A Clinical Companion (Paperback, 7th New edition): Raif Geha, Luigi Notarangelo Case Studies in Immunology - A Clinical Companion (Paperback, 7th New edition)
Raif Geha, Luigi Notarangelo
R1,143 R953 Discovery Miles 9 530 Save R190 (17%) Shipped within 7 - 13 working days

Case Studies in Immunology, Seventh Edition is intended for medical students and undergraduate and graduate students in immunology. It presents major topics of immunology through a selection of clinical cases that reinforce and extend the basic science. Each case history is preceded by essential scientific facts about the immunological mechanisms of that specific disorder. The cases themselves demonstrate how immunological problems are deconstructed in the clinic and each one is followed by a concise summary of the clinical finding and questions which can serve as discussion points. The book includes a total of 55 cases and can be used as either a standalone text, review aid, or as a companion to Janeway's Immunobiology, Ninth Edition and The Immune System, Fourth Edition.

How the Immune System Works (Paperback, 6th Edition): Lauren M. Sompayrac How the Immune System Works (Paperback, 6th Edition)
Lauren M. Sompayrac
R693 R549 Discovery Miles 5 490 Save R144 (21%) Shipped within 7 - 13 working days

How the Immune System Works has helped thousands of students understand what's in their hefty immunology tomes and textbooks. In this book, Dr. Sompayrac cuts through the jargon and details to reveal, in simple language, the essence of this complex subject: how the immune system fits together, how it protects us from disease and, perhaps most importantly, why it works the way it does.

Elegant Defense, An - The Extraordinary New Science of the Immune System: A Tale in Four Lives (Hardcover): Matt Richtel Elegant Defense, An - The Extraordinary New Science of the Immune System: A Tale in Four Lives (Hardcover)
Matt Richtel
R475 R330 Discovery Miles 3 300 Save R145 (31%) Shipped within 7 - 12 working days

Magnificently reported and soulfully crafted, An Elegant Defense is an epic, first-of-its-kind exploration of the human immune system and the secrets of health, by the Pulitzer Prize-winning New York Times journalist "Vividly told. ... Explicates for the lay reader the intricate biology of our immune system." -JEROME GROOPMAN, New York Review of Books "One of those rare nonfiction books that transcends the genre. ... Extraordinary." -DOUGLAS PRESTON A National Indie Bestseller A terminal cancer patient rises from the grave. A medical marvel defies HIV. Two women with autoimmunity discover their own bodies have turned against them. Matt Richtel's An Elegant Defense uniquely entwines these intimate stories with science's centuries-long quest to unlock the mysteries of sickness and health, and illuminates the immune system as never before. The immune system is our body's essential defense network, a guardian vigilantly fighting illness, healing wounds, maintaining order and balance, and keeping us alive. Its legion of microscopic foot soldiers-from T cells to "natural killers"-patrols our body, linked by a nearly instantaneous communications grid. It has been honed by evolution over millennia to face an almost infinite array of threats. For all its astonishing complexity, however, the immune system can be easily compromised by fatigue, stress, toxins, advanced age, and poor nutrition-hallmarks of modern life-and even by excessive hygiene. Paradoxically, it is a fragile wonder weapon that can turn on our own bodies with startling results, leading today to epidemic levels of autoimmune disorders. Richtel effortlessly guides readers on a scientific detective tale winding from the Black Plague to twentieth-century breakthroughs in vaccination and antibiotics, to the cutting-edge laboratories that are revolutionizing immunology-perhaps the most extraordinary and consequential medical story of our time. The foundation that Richtel builds makes accessible revelations about cancer immunotherapy, the microbiome, and autoimmune treatments that are changing millions of lives. An Elegant Defense also captures in vivid detail how these powerful therapies, along with our behavior and environment, interact with the immune system, often for the good but always on a razor's edge that can throw this remarkable system out of balance. Drawing on his groundbreaking reporting for the New York Times and based on extensive new interviews with dozens of world-renowned scientists, Matt Richtel has produced a landmark book, equally an investigation into the deepest riddles of survival and a profoundly human tale that is movingly brought to life through the eyes of his four main characters, each of whom illuminates an essential facet of our "elegant defense."

The End of the Beginning - Cancer, Immunity, and the Future of a Cure (Hardcover): Michael Kinch The End of the Beginning - Cancer, Immunity, and the Future of a Cure (Hardcover)
Michael Kinch
R527 R426 Discovery Miles 4 260 Save R101 (19%) Shipped within 7 - 13 working days
Cancer Immunology - Cancer Immunotherapy for Organ-Specific Tumors (Hardcover): Nima Rezaei Cancer Immunology - Cancer Immunotherapy for Organ-Specific Tumors (Hardcover)
Nima Rezaei
R4,010 R3,140 Discovery Miles 31 400 Save R870 (22%) Shipped within 7 - 12 working days

Cancer Immunology is intended as an up-to-date, clinically relevant review of cancer immunology and immunotherapy. This volume focuses on the immunopathology and immunotherapy of organ cancers in detail. It clearly explains their immunology and describes novel immunotherapy for specific cancers, including pediatric solid tumors, hematologic malignancies, gastrointestinal tumors, skin cancers, bone and connective tissue tumors, central nervous system tumors, lung cancers, genitourinary tract tumors and breast cancers. In so doing, it builds on the previous two volumes in Cancer Immunology, placing basic knowledge on tumor immunology and immunotherapy into a clinical perspective with the aim of educating clinicians on advances in cancer immunology and the most recent approaches in the immunotherapy of various tumors. This translational, clinically oriented book will be of special value to clinical immunologists, hematologists and oncologists.

Biological Effects of Fibrous and Particulate Substances (Hardcover, 1st ed. 2016): Takemi Otsuki, Yasuo Yoshioka, Andrij Holian Biological Effects of Fibrous and Particulate Substances (Hardcover, 1st ed. 2016)
Takemi Otsuki, Yasuo Yoshioka, Andrij Holian; Volume editing by Takemi Otsuki
R2,708 R2,447 Discovery Miles 24 470 Save R261 (10%) Shipped within 7 - 12 working days

This volume examines our current understanding of the biological effects of fibrous and particulate substances, including discussions on nanoparticles. It offers comprehensive information on the latest insights into the immunological effects of various irritants on the human body. Readers will benefit from the contributing authors' diverse perspectives and extensive discussions of key issues, which include molecular alterations of the immune system and autoimmune diseases in connection with asbestos and silica, among others. The chapters also discuss recommendations, practical methods, and nanosafety science in situations involving exposure to nanotoxic substances. Edited in collaboration with the Japanese Society for Hygiene, this book provides up-to-date information on the immunological effects of nanotoxic substances to researchers interested in environmental and occupational health. Presenting a number of recent concepts and findings in the field, it enables readers to gain a comprehensive knowledge of health problems caused by environmental fibrous and particulate substances.

Skin Diseases in the Immunocompromised (Hardcover, 2014 ed.): John C Hall Skin Diseases in the Immunocompromised (Hardcover, 2014 ed.)
John C Hall
R3,096 R2,757 Discovery Miles 27 570 Save R339 (11%) Shipped within 7 - 12 working days

As the number of surviving immune suppressed patients continues to rise, skin manifestations of patients have become increasingly important. AIDS patients, and renal, heart, liver, bone marrow, and lung transplant patients are now living longer and immunosuppressive drugs are being used more frequently. Diabetes is rising in the US and around the world, offering its own unique brand of immune suppressed skin diseases. The skin may be the earliest sign of these conditions and be the organ showing the most profound, earliest, and treatment limiting side effects. Skin Diseases in the Immunocompromised is the most comprehensive book on the topic available. It elucidates the signs of immune suppressed skin diseases to afford early diagnosis and management of this ever-increasing diverse group of illnesses. Organized for easy access, this book will be an essential resource for residents and fellows in dermatology and infectious diseases medical professionals.

Cancer Immunotherapy Meets Oncology - In Honor of Christoph Huber (Hardcover, 2014 ed.): Cedrik Michael Britten, Sebastian... Cancer Immunotherapy Meets Oncology - In Honor of Christoph Huber (Hardcover, 2014 ed.)
Cedrik Michael Britten, Sebastian Kreiter, Mustafa Diken, Hans-Georg Rammensee
R2,885 R2,572 Discovery Miles 25 720 Save R313 (11%) Shipped within 7 - 12 working days

This book provides a comprehensive update on the state of the art in cancer immunology, which has rapidly evolved from a field of clinical research into an established discipline of oncology. The key recent developments in immuno-oncology are all covered, from the ever-changing immunological and regulatory frameworks to the most promising therapeutic concepts. Themes include combination therapies and personalized medicine, as well as identification of biomarkers to guide the clinical development of new approaches and to pinpoint the optimal treatment for each patient. The book acknowledges the continuing dynamic nature of the field as reflected in the development of next-generation immunotherapies that are already in clinical testing.

"Cancer Immunotherapy Meets Oncology" is dedicated to the lifetime achievements of Christoph Huber, founder and chair of the Association for Cancer Immunotherapy (CIMT). It is also a tribute to those researchers and clinicians who are striving to develop novel diagnostics and tailored immunotherapies for the benefit of cancer patients.

Prokaryotic Metabolism and Physiology (Paperback, 2nd Revised edition): Byung Hong Kim, Geoffrey Michael Gadd Prokaryotic Metabolism and Physiology (Paperback, 2nd Revised edition)
Byung Hong Kim, Geoffrey Michael Gadd
R1,158 R1,097 Discovery Miles 10 970 Save R61 (5%) Shipped within 7 - 12 working days

Vast numbers of different prokaryotic microorganisms shape the biosphere, with diverse metabolic capabilities. Determination of genome sequences for a wide range of bacteria and archaea now requires an in-depth knowledge of prokaryotic metabolic function to give biochemical, physiological and ecological meaning to the genomic information. This new edition describes up-to-date knowledge of the key metabolic processes that occur under different conditions, and the cellular processes that determine prokaryotic roles in the environment, biotechnology and human health. Essential for students of microbiology, applied microbiology, biotechnology, genomics and systems biology, this advanced textbook covers prokaryotic structure, composition, nutrient transport, biosynthesis and growth. Newly characterised metabolic pathways are included, as well as the latest understanding of metabolic regulation and stress responses. Additionally, the link between energetics, growth and survival is discussed as well as the maintenance of genetic integrity by the bacterial immune system.

Immunology - A Short Course (Paperback, 7th Edition): Richard Coico, Geoffrey Sunshine Immunology - A Short Course (Paperback, 7th Edition)
Richard Coico, Geoffrey Sunshine
R1,129 R884 Discovery Miles 8 840 Save R245 (22%) Shipped within 7 - 13 working days

Immunology: A Short Course, 7th Edition introduces all the critical topics of modern immunology in a clear and succinct yet comprehensive fashion. The authors offer uniquely-balanced coverage of classical and contemporary approaches and basic and clinical aspects. The strength of Immunology: A Short Course is in providing a complete review of modern immunology without the burden of excessive data or theoretical discussions. Each chapter is divided into short, self-contained units that address key topics, illustrated by uniformly drawn, full-color illustrations and photographs. This new edition of Immunology: A Short Course: Has been fully revised and updated, with a brand new art program to help reinforce learning Includes a new chapter on Innate Immunity to reflect the growth in knowledge in this area Highlights important therapeutic successes resulting from targeted antibody therapies Includes end of chapter summaries and review questions, a companion website at www.wileyimmunology.com/coico featuring interactive flashcards, USMLE-style interactive MCQs, figures as PowerPoint slides, and case-based material to help understand clinical applications

The Beautiful Cure - The Revolution in Immunology and What It Means for Your Health (Hardcover): Daniel M. Davis The Beautiful Cure - The Revolution in Immunology and What It Means for Your Health (Hardcover)
Daniel M. Davis
R488 R388 Discovery Miles 3 880 Save R100 (20%) Shipped within 7 - 11 working days

"Visceral."--Wall Street Journal "Illuminating."--Publishers Weekly "Heroic."--Science The immune system holds the key to human health. In The Beautiful Cure, leading immunologist Daniel M. Davis describes how the scientific quest to understand how the immune system works--and how it is affected by stress, sleep, age, and our state of mind--is now unlocking a revolutionary new approach to medicine and well-being. The body's ability to fight disease and heal itself is one of the great mysteries and marvels of nature. But in recent years, painstaking research has resulted in major advances in our grasp of this breathtakingly beautiful inner world: a vast and intricate network of specialist cells, regulatory proteins, and dedicated genes that are continually protecting our bodies. Far more powerful than any medicine ever invented, the immune system plays a crucial role in our daily lives. We have found ways to harness these natural defenses to create breakthrough drugs and so-called immunotherapies that help us fight cancer, diabetes, arthritis, and many age-related diseases, and we are starting to understand whether activities such as mindfulness might play a role in enhancing our physical resilience. Written by a researcher at the forefront of this adventure, The Beautiful Cure tells a dramatic story of scientific detective work and discovery, of puzzles solved and mysteries that linger, of lives sacrificed and saved. With expertise and eloquence, Davis introduces us to this revelatory new understanding of the human body and what it takes to be healthy.

Basic Immunology - Functions and Disorders of the Immune System (Paperback, 6th Revised edition): Abul K. Abbas, Andrew H H... Basic Immunology - Functions and Disorders of the Immune System (Paperback, 6th Revised edition)
Abul K. Abbas, Andrew H H Lichtman, Shiv Pillai
R1,251 R1,028 Discovery Miles 10 280 Save R223 (18%) Shipped within 7 - 12 working days

Meticulously reviewed and updated for today's medical students, Basic Immunology, 6th Edition, is a concise text expertly written by the same distinguished author team as the best-selling, comprehensive text, Cellular and Molecular Immunology. This focused, easy-to-understand volume uses full-color illustrations and clinical images, useful tables, and practical features such as Summary Point boxes, end-of-chapter review questions, glossary terms, and clinical cases-all designed to help students master this complex topic in the most efficient, effective manner possible. Emphasizes clinical aspects of immunology, including disease pathogenesis, the development of novel therapies based on basic science, and an appendix of clinical cases for real-world application. Provides top-notch instruction from experienced teachers, course directors, and lecturers led by well-known editor and author Dr. Abul Abbas. Features a highly readable writing style and practical organization, now with fully revised content and updated images to reflect recent important advances in today's understanding of the immune system. Provides additional online features such as answers to in-book chapter review questions, helpful animations, and self-assessment questions. Presents information in a format and style that maximizes usefulness to students and teachers studying medicine, allied health fields, and biology. Contains numerous features designed to help students understand key immunologic concepts: high-quality illustrations, practical tables, chapter outlines, bolded key points, and focus questions in every chapter for self-assessment and review. Includes an Enhanced eBook version with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.

Neuro-Immuno-Gastroenterology (Hardcover, 1st ed. 2016): Cris S Constantinescu, Razvan Arsenescu, Violeta Arsenescu Neuro-Immuno-Gastroenterology (Hardcover, 1st ed. 2016)
Cris S Constantinescu, Razvan Arsenescu, Violeta Arsenescu
R4,140 R3,330 Discovery Miles 33 300 Save R810 (20%) Shipped within 7 - 12 working days

This book addresses important issues regarding the interaction between the nervous system, the immune system, and the digestive system. Gut flora has a profound influence on the shaping of the immune response, not only in the gastrointestinal system but also in the nervous system. Fascinatingly, manipulation of intestinal immune responses can be used to modulate neurological disease. Conversely, the nervous system and the psyche have significant effects on the functioning of the gut and liver. After introductory chapters on the neurology, the immunology and microbiology of the gut, the effects of the gut immune system and gut flora and its manipulation on neurological disease are discussed, followed by molecular mimicry and immune tolerance in neuroimmune diseases. Additionally, several chapters deal with gastrointestinal manifestations of neurological diseases. Neuro-Immuno-Gastroenterology is aimed at neurologists, gastroenterologists, and immunologists.

Advances in Transplant Dermatology - Clinical and Practical Implications (Hardcover, 2015 ed.): Fiona Zwald, Marc D. Brown Advances in Transplant Dermatology - Clinical and Practical Implications (Hardcover, 2015 ed.)
Fiona Zwald, Marc D. Brown
R3,091 R2,170 Discovery Miles 21 700 Save R921 (30%) Shipped within 7 - 12 working days

This book provides an informative update on scientific advances relating to transplant dermatology that may be applicable to clinical practice. Commentary is provided on the emerging role of viruses in transplant dermatology, the management of skin disease secondary to transplant medication, sunscreen use in transplant recipients, the role of revision of immunosuppression, and advances in photodynamic therapy. The latest staging and management criteria for high-risk squamous cell carcinoma and the implications for clinical practice are then analyzed. Finally, the management of other cutaneous malignancies is discussed, covering malignant melanoma, Merkel cell carcinoma, and rarer tumors that also behave aggressively and require special consideration in solid organ transplant patients. Each particular advance is addressed in an individual chapter by leaders in the field. The book both expands current knowledge and complements previous textbooks on the subject.

Essential Clinical Immunology (Paperback): John B. Zabriskie Essential Clinical Immunology (Paperback)
John B. Zabriskie
R1,251 R1,084 Discovery Miles 10 840 Save R167 (13%) Shipped within 7 - 12 working days

The ways in which we can better understand cancer, HIV, and other autoimmune diseases through clinical immunology are of great interest to practitioners from the student level to the advanced PhD. Designed as an introduction for practitioners and residents, this book focuses on the clinical disease-state level of immunology. Essential Clinical Immunology" begins with the basic concepts and then details the immunological aspects of various disease states involving major organs of the body. The book explores how we can better understand disease and its treatment through clinical immunology. Looking forward, each chapter concludes with patterns for future research.

Molecular Immunotoxicology (Hardcover): Emanuela Corsini, Hendrik van Loveren Molecular Immunotoxicology (Hardcover)
Emanuela Corsini, Hendrik van Loveren
R2,993 R2,389 Discovery Miles 23 890 Save R604 (20%) Shipped within 7 - 12 working days

The human immune system is constantly exposed to chemical contaminants, whether from food, water or air. Some chemicals directly elicit an immune response, while others indirectly activate or deactivate components within the immune system. Thus when tracking or predicting the effect of a chemical on the immune system, many different pathways and modes of action need to be considered. Following an introduction to the various pathways and toxicity mechanisms from a systemic perspective, the main part of this comprehensive reference surveys individual molecular mechanisms of important immunotoxicants, from PAHs to biopharmaceuticals, and from receptor-mediated toxicity to nanoparticle toxicity, using analyses based on molecular effects rather than on animal models. Taken together, the knowledge presented here provides an up-to-date overview of this hot topic that can be directly applied to the prediction and characterization of immunotoxic effects in drugs, chemicals, and environmental contaminants.

Roitt's Essential Immunology (Paperback, 13th Edition): Peter J. Delves, Seamus J. Martin, Dennis R. Burton, Ivan M. Roitt Roitt's Essential Immunology (Paperback, 13th Edition)
Peter J. Delves, Seamus J. Martin, Dennis R. Burton, Ivan M. Roitt
R1,234 R967 Discovery Miles 9 670 Save R267 (22%) Shipped within 7 - 13 working days

Roitt's Essential Immunology - the textbook of choice for students and instructors of immunology worldwide Roitt s Essential Immunology clearly explains the key principles needed by medical and health sciences students, from the basis of immunity to clinical applications. A brand new introduction sets the scene to section 1, Fundamentals of Immunology, introducing the microbial world and the strategies the body employs to defend itself. Each chapter then guides the reader through a different part of the immune system, and explains the role of each cell or molecule individually, and then as a whole. Section 2, Applied Immunology, discusses what happens when things go wrong, and the role the immune system plays alongside the damaging effects of a disease, including cancer, immunodeficiency, allergies and transplantation and the beneficial effects of vaccines. The 13th edition continues to be a user-friendly and engaging introduction to the workings of the immune system, whilst supporting those who require a slightly more detailed understanding of the key developments in immunology. The content has been fully updated throughout and includes: * An expansion on key clinical topics, including: innate immunity, autoimmune conditions, asthma, primary immunodeficiency, and HIV/AIDS * Beautifully presented with improved artwork and new illustrations * A range of learning features, including introduction re-cap boxes, end of chapter and section summaries to aid revision, as well as further reading suggestions, and a glossary to explain the most important immunology terms. Roitt's Essential Immunology is also supported by a companion website at www.roitt.com including: * An additional online only chapter on immunological methods and applications * Further interactive multiple choice and single best answer questions for each chapter * Animations and videos showing key concepts * Fully downloadable figures and illustrations, further reading and useful links * Updated extracts from the Encyclopaedia of Life Sciences * Podcasts to reinforce the key principles explained in the text

Practical Algorithms in Pediatric Endocrinology - (Practical Algorithms in Pediatrics. Series Editor: Z. Hochberg) (Spiral... Practical Algorithms in Pediatric Endocrinology - (Practical Algorithms in Pediatrics. Series Editor: Z. Hochberg) (Spiral bound, 3rd Revised edition)
Z. Hochberg
R1,116 R917 Discovery Miles 9 170 Save R199 (18%) Shipped within 7 - 12 working days

Algorithms provide a logical, concise and cost-effective approach to medical reasoning: utilizing a concise, step-by-step approach based upon clues from the history, physical examination and laboratory studies, algorithms help avoid excessive unnecessary procedures and testing. The 3rd, revised edition of Practical Algorithms in Pediatric Endocrinology deals with practical issues of child growth, puberty, diseases of the endocrine glands, sexual differentiation, as well as aberrations of water, electrolyte, mineral and carbohydrate metabolism. Fifty-six clinical issues are covered by an algorithmic approach, breaking down long lists and tables of differential diagnosis into smaller, more manageable ones. Common clinical symptoms, signs and laboratory abnormalities are classified as they present themselves at the patient's bedside. This book is aimed at general practitioners and pediatricians, in particular those who are not exposed to pediatric endocrine problems on a daily basis, and at trainees in endocrinology and pediatric endocrinology as they acquire familiarity with clinical problem solving to make rational choices when facing clinical dilemmas.

Chemokine Receptors as Drug Targets (Hardcover): Martine J. Smit, Sergio A. Lira, Rob Leurs Chemokine Receptors as Drug Targets (Hardcover)
Martine J. Smit, Sergio A. Lira, Rob Leurs; Series edited by Raimund Mannhold, Hugo Kubinyi, …
R3,627 R2,869 Discovery Miles 28 690 Save R758 (21%) Shipped within 7 - 12 working days

Chemokines are hormone-like signaling molecules secreted by cells to signal infection and guide the immune response. Following a decade of basic chemokine research, the pharmaceutical industry has now begun to exploit this crucial signaling pathway for the development of innovative drugs against AIDS, cancer, neural and autoimmune diseases. Here is the first reference focusing on these novel drug development opportunities. Opening with a general introduction on chemokine function and chemokine receptor biology, the second part covers the known implications of these signaling molecules in human diseases, such as cancer, neural disorders, and viral infection, including AIDS. The third part systematically surveys current drug development efforts at targeting individual chemokine receptors, as well as other chemokine interaction partners, including up-to-date reports from the pharmaceutical industry.

Between Hope and Fear - A History of Vaccines and Human Immunity (Hardcover): Michael Kinch Between Hope and Fear - A History of Vaccines and Human Immunity (Hardcover)
Michael Kinch
R538 R423 Discovery Miles 4 230 Save R115 (21%) Shipped within 7 - 11 working days
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