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Books > Medicine > Clinical & internal medicine > Diseases & disorders > Immunology > General

Cytokines (Hardcover): Payam Behzadi Cytokines (Hardcover)
Payam Behzadi
R3,335 Discovery Miles 33 350 Ships in 10 - 15 working days
Tumor Immunology, Volume 130 (Hardcover): Robert Schreiber Tumor Immunology, Volume 130 (Hardcover)
Robert Schreiber
R5,539 R4,638 Discovery Miles 46 380 Save R901 (16%) Ships in 12 - 19 working days

Advances in Immunology, a long-established and highly respected publication, presents current developments as well as comprehensive reviews in immunology. Articles address the wide range of topics that comprise immunology, including molecular and cellular activation mechanisms, phylogeny and molecular evolution, and clinical modalities. Edited and authored by the foremost scientists in the field, each volume provides up-to-date information and directions for the future. This volume focuses on tumor immunology.

Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging - Volume 8Human Diseases (Hardcover): M. A.... Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging - Volume 8Human Diseases (Hardcover)
M. A. Hayat
R4,446 R4,133 Discovery Miles 41 330 Save R313 (7%) Ships in 12 - 19 working days

Understanding the importance and necessity of the role of autophagy in health and disease is vital for the studies of cancer, aging, neurodegeneration, immunology, and infectious diseases. Comprehensive and forward-thinking, these books offer a valuable guide to both cellular processes while inciting researchers to explore their potentially important connections. Volume 8 Autophagy and Human Diseases, concentrates on the role of Autophagy in human diseases, including tumorigenesis. The diseases discussed include melanoma, liver cancer, pancreatic cancer, and neurodegenerative disorders. Loss of autophagy in the central nervous system causes neurodegeneration (Alzheimers disease, Huntington's disease, Parkin's disease, and Amyotrophic Lateral Sclerosis). Melanoma is one of the most serious diseases in humans. Autophagy plays a key role in the anticancer response to Chemotherapy. However, autophagy can increase or decrease the effectiveness of chemotherapy. The reasons for these contradictory effects are explained. Autophagy also plays a role in idiopathic inflammatory diseases, infection, and immunity. An explanation is given how autophagy is closely linked to control of innate and adaptive immune responses in host defense in part by regulating cytokine production. The role of autophagy in cutaneous malignant melanoma is discussed in detail and expression of Beclin 1 and LC3 autophagic genes in melanoma is included to explain the molecular mechanisms underlying this very serious disease, which tends to metastasize to the brain. The effect of the treatment of this disease using Terfenadine through the induction of autophagy and apoptosis is also included. Autophagy and apoptosis are two main mechanisms involved in programmed cell death. Considering that autophagy is associated with numerous biological processes including cellular development and differentiation, cancer (both antitumor and protumor functions), immunity, infectious diseases, inflammation, maintenance of homeostasis, response to cellular stress, and degenerative diseases such as Alzheimer's, Parkinson's, Huntington's, amyotrophic lateral sclerosis, and prion diseases, there is a great need to understanding its role. Cell homeostasis is achieved by balancing biosynthesis and cellular turnover. In spite of the increasing importance of autophagy in various pathophysiological situations (conditions) mentioned above, this process remains underestimated and overlooked. As a consequence, its role in the initiation, stability, maintenance, and progression of these and other diseases (e.g., autoimmune disease) remains poorly understood. Volumes in the Series Volume 1: Molecular Mechanisms. Elucidates autophagy's association with numerous biological processes, including cellular development and differentiation, cancer, immunity, infectious diseases, inflammation, maintenance of homeostasis, response to cellular stress, and degenerative diseases such as Alzheimer's, Parkinson's, Huntington's, amyotrophic lateral sclerosis, and prion diseases. Volume 2: Role in General Diseases. Describes the various aspects of the complex process of autophagy in a myriad of devastating human diseases, expanding from a discussion of essential autophagic functions into the role of autophagy in proteins, pathogens, immunity, and general diseases. Volume 3: Role in Specific Diseases. Explores the role of autophagy in specific diseases and developments, including: Crohn's Disease, Gaucher Disease, Huntington's Disease, HCV infection, osteoarthritis, and liver injury, with a full section devoted to in-depth exploration of autophagy in tumor development and cancer, as well as the relationship between autophagy and apoptosis. Volume 4: Mitophagy. Presents detailed information on the role of mitophagy, the selective autophagy of mitochondria, in health and disease, by delivering an in-depth treatment of the molecular mechanisms involved in mitophagy initiation and execution, as well as the role of mitophagy in Parkinson Disease, cardiac aging, and skeletal muscle atrophy. Volume 5: Role in Human Diseases. Comprehensively describes the role of autophagy in human diseases, delivering coverage of the antitumor and protumor roles of autophagy; the therapeutic inhibition of autophagy in cancer; and the duality of autophagy's effects in various cardiovascular, metabolic, and neurodegenerative disorders. Volume 6: Regulation of Autophagy and Selective Autophagy. Provides coverage of the mechanisms of regulation of autophagy; intracellular pathogen use of the autophagy mechanism; the role of autophagy in host immunity; and selective autophagy. Volume 7: Role of Autophagy in Therapeutic Applications. Provides coverage of the latest developments in autophagosome biogenesis and regulation; the role of autophagy in protein quality control; the role of autophagy in apoptosis; autophagy in the cardiovascular system; and the relationships between autophagy and lifestyle. Volume 8: Autophagy and Human Diseases. Reviews recent advancements in the molecular mechanisms underlying a large number of genetic and epigenetic diseases and abnormalities, and introduces new, more effective therapeutic strategies, in the development of targeted drugs and programmed cell death, providing information that will aid on preventing detrimental inflammation. Volume 9: Human Diseases and Autophagosome. Emphasizes the role of Autophagy in necrosis and inflammation, explaining in detail the molecular mechanism(s) underlying the formation of autophagosomes, including the progression of Omegasomes to autophagosomes.

Drug Hypersensitivity, An Issue of Immunology and Allergy Clinics of North America, Volume 42-2 (Hardcover): Elizabeth Phillips Drug Hypersensitivity, An Issue of Immunology and Allergy Clinics of North America, Volume 42-2 (Hardcover)
Elizabeth Phillips
R2,170 Discovery Miles 21 700 Ships in 12 - 19 working days

In this issue of Immunology & Allergy Clinics, guest editor Dr. Elizabeth J. Phillips brings her considerable expertise to the topic of Drug Hypersensitivity. Top experts in the field cover key topics such as perioperative anaphylaxis; telemedicine in drug hypersensitivity; aspirin-exacerbated respiratory disease; pediatric drug allergy; and more. Contains 15 relevant, practice-oriented topics including excipient allergy; recognizing drug hypersensitivity in skin of color; allergy to radiocontrast dye; MRGRPX2 and its role in non-IgE-mediated mast cell activation; and more. Provides in-depth clinical reviews on drug hypersensitivity, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

Advances in Immunology, Volume 129 (Hardcover): Frederick Alt Advances in Immunology, Volume 129 (Hardcover)
Frederick Alt
R5,546 R4,645 Discovery Miles 46 450 Save R901 (16%) Ships in 12 - 19 working days

Advances in Immunology, a long-established and highly respected publication, presents current developments as well as comprehensive reviews in immunology. Articles address the wide range of topics that comprise immunology, including molecular and cellular activation mechanisms, phylogeny and molecular evolution, and clinical modalities. Edited and authored by the foremost scientists in the field, each volume provides up-to-date information and directions for the future.

Immunoinformatics of Cancers - Practical Machine Learning Approaches Using R (Paperback): Nima Rezaei, Parnian Jabbari Immunoinformatics of Cancers - Practical Machine Learning Approaches Using R (Paperback)
Nima Rezaei, Parnian Jabbari
R3,698 Discovery Miles 36 980 Ships in 12 - 19 working days

Immunoinformatics of Cancers: Practical Machine Learning Approaches Using R takes a bioinformatics approach to understanding and researching the immunological aspects of malignancies. It details biological and computational principles and the current applications of bioinformatic approaches in the study of human malignancies. Three sections cover the role of immunology in cancers and bioinformatics, including databases and tools, R programming and useful packages, and present the foundations of machine learning. The book then gives practical examples to illuminate the application of immunoinformatics to cancer, along with practical details on how computational and biological approaches can best be integrated. This book provides readers with practical computational knowledge and techniques, including programming, and machine learning, enabling them to understand and pursue the immunological aspects of malignancies.

Osteogenesis and Bone Regeneration (Hardcover): Haisheng Yang Osteogenesis and Bone Regeneration (Hardcover)
Haisheng Yang
R3,320 Discovery Miles 33 200 Ships in 10 - 15 working days
Managing Treatment-Resistant Depression - Road to Novel Therapeutics (Paperback): Joao Luciano de Quevedo, Patricio Riva Posse,... Managing Treatment-Resistant Depression - Road to Novel Therapeutics (Paperback)
Joao Luciano de Quevedo, Patricio Riva Posse, William V. Bobo
R5,217 Discovery Miles 52 170 Ships in 12 - 19 working days

Managing Treatment-Resistant Depression: Road to Novel Therapeutics defines TRD for readers, discussing the clinical and epidemiological predictors, economic burden and neurobiological factors. In addition, staging methods for treatment resistance are fully covered in this book, including serotonin specific reuptake inhibitors, serotonin norepinephrine reuptake inhibitors, other classes of antidepressants, including tricyclic antidepressants and monoamine oxidase inhibitors, augmentation strategies, and newer antidepressant treatments like ketamine and esketamine. In addition, evidence supporting the use of psychotherapies and neuromodulation strategies are also reviewed. Written by top experts in the field, this book is the first of its kind to review all methods of treatment for TRD.

Translational Autoimmunity, Volume 3 - Autoimmune Disease Associated with Different Clinical Features (Paperback): Nima Rezaei Translational Autoimmunity, Volume 3 - Autoimmune Disease Associated with Different Clinical Features (Paperback)
Nima Rezaei
R3,678 Discovery Miles 36 780 Ships in 12 - 19 working days

Translational Autoimmunity: Autoimmune Diseases in Different Clinical Settings addresses autoimmunity and associated conditions, such as aging, infectious diseases, cancer, neurodegeneration, psychological disorders, fertility, inflammatory vascular diseases, and interstitial lung diseases. The book addresses sufficiently basic questions on how the immune system is designed to distinguish self from no self and behave such that it's able to maintain self-tolerance, how does it work in infections, and how it elicits an auto-reactive state and develops self-antigens seen in autoimmune conditions. This is followed by an overview on the genetic and clinical aspects of the spectrum of autoimmune diseases which are broadly categorized into two types of organ specific autoimmune diseases and non-organ specific autoimmune diseases (also known as systemic autoimmune diseases).

Molecular Mechanisms that Orchestrate the Assembly of Antigen Receptor Loci, Volume 128 (Hardcover): Cornelis Murre Molecular Mechanisms that Orchestrate the Assembly of Antigen Receptor Loci, Volume 128 (Hardcover)
Cornelis Murre
R5,317 R4,455 Discovery Miles 44 550 Save R862 (16%) Ships in 12 - 19 working days

Molecular Mechanisms That Orchestrate the Assembly of Antigen Receptor Loci, the latest volume in the Advances in Immunology series focuses on the generation of an effective immune response to invading pathogens As B and T lymphocytes are characterized by the expression of antigen receptors that specifically recognize determinants expressed on pathogens, this volume discusses how antigen receptors are synthesized in B and T lymphocytes.

Immunogenetics: A Molecular and Clinical Overview - Clinical Applications of Immunogenetics (Paperback): Muneeb U Rehman, Azher... Immunogenetics: A Molecular and Clinical Overview - Clinical Applications of Immunogenetics (Paperback)
Muneeb U Rehman, Azher Arafah, Md. Niamat Ali, Shafat Ali
R3,718 Discovery Miles 37 180 Ships in 12 - 19 working days

Clinical Applications of Immunogenetics: Immunogenetics: A Molecular and Clinical Overview, Volume II provides readers with an exclusive, updated overview of scientific knowledge, achievements and findings in the field of immunogenetics. In thirteen chapters, the book gives insights in new advancements and approaches in viral and autoimmune diseases. Specific chapters are dedicated to immunogenetic mechanisms in the treatment of immune disorders, cancer, neurological and neurodegenerative disorders. In addition, other chapters cover immunogenomics in precision medicine, clinical medicine and transplantation. Finally, a special chapter, COVID-19: A novel challenge to human immune-genetic machinery, updates on thoughts surrounding the pandemic.

Recent Advancements in Microbial Diversity - Macrophages and their Role in Inflammation (Paperback): Jae Youl Cho Recent Advancements in Microbial Diversity - Macrophages and their Role in Inflammation (Paperback)
Jae Youl Cho
R4,269 Discovery Miles 42 690 Ships in 12 - 19 working days

In recent years, researchers around the globe have deep dived into the fascination world of the Macrophage and its diverse role in tissue development, angiogenesis, and wound healing, and above all the untapped mystery of the wondering immune system within our body. Macrophages and their role in inflammation includes all the latest information of macrophages and inflammation as well as it provides an in-depth understanding of this complex and rapidly progressing field of study.

Immunotherapy of Cancer, Volume 128 (Hardcover): Xiang-Yang Wang, Paul B. Fisher Immunotherapy of Cancer, Volume 128 (Hardcover)
Xiang-Yang Wang, Paul B. Fisher
R4,695 R3,936 Discovery Miles 39 360 Save R759 (16%) Ships in 12 - 19 working days

Immunotherapy of Cancer provides information on cancer research related to inflammation and immunity, containing outstanding reviews by experts in the field. It is suitable for researchers and students who have an interest in cancer immunobiology.

Advances in Immunology, Volume 127 (Hardcover): Frederick W. Alt Advances in Immunology, Volume 127 (Hardcover)
Frederick W. Alt
R5,307 R4,445 Discovery Miles 44 450 Save R862 (16%) Ships in 12 - 19 working days

Advances in Immunology, a long-established and highly respected publication, presents current developments as well as comprehensive reviews in immunology. Articles address the wide range of topics that comprise immunology, including molecular and cellular activation mechanisms, phylogeny and molecular evolution, and clinical modalities. Edited and authored by the foremost scientists in the field, each volume provides up-to-date information and directions for the future.

The Lung in Autoimmune Diseases, Volume 17 (Paperback): Fabiola Atzeni, Jose Gomez-Puerta, Jacobo Sellares The Lung in Autoimmune Diseases, Volume 17 (Paperback)
Fabiola Atzeni, Jose Gomez-Puerta, Jacobo Sellares
R3,167 Discovery Miles 31 670 Ships in 12 - 19 working days

The Lung in Autoimmune Diseases, Volume Seventeen identifies and describes the role of the lung in the most common systemic autoimmune diseases. From disease patterns, prognosis and risks to treatment, this book provides a comprehensive approach for the role of the lung in autoimmune diseases and the influence of autoimmune disease on the lung's functionality. In recent years, there is increasing knowledge in the field, including lung infection in early disease stages, mechanisms involved in lung damage, and new treatments. Recognition of lung involvement and implementation of some specific therapies is an important issue for clinicians dealing with systemic autoimmune diseases.

Advances in Immunology, Volume 126 (Hardcover): Frederick W. Alt Advances in Immunology, Volume 126 (Hardcover)
Frederick W. Alt
R5,298 R4,436 Discovery Miles 44 360 Save R862 (16%) Ships in 12 - 19 working days

Advances in Immunology, a long-established and highly respected publication, presents current developments as well as comprehensive reviews in immunology. Articles address the wide range of topics that comprise immunology, including molecular and cellular activation mechanisms, phylogeny and molecular evolution, and clinical modalities. Edited and authored by the foremost scientists in the field, each volume provides up-to-date information and directions for the future.

The Regulation of Expression of Terminal Deoxynucleotidyl Transferase in an Inducible Murine Pre-B Cell Line (Hardcover): Randy... The Regulation of Expression of Terminal Deoxynucleotidyl Transferase in an Inducible Murine Pre-B Cell Line (Hardcover)
Randy Horwitz
R2,273 Discovery Miles 22 730 Ships in 10 - 15 working days
Translational Autoimmunity, Volume 2 - Treatment of Autoimmune Diseases (Paperback): Nima Rezaei Translational Autoimmunity, Volume 2 - Treatment of Autoimmune Diseases (Paperback)
Nima Rezaei
R3,647 Discovery Miles 36 470 Ships in 12 - 19 working days

Translational Autoimmunity: Treatment of Autoimmune Diseases, Volume Two in the Translational Immunology series, focuses on advances in therapeutic modalities in autoimmune diseases. Efficacy and safety of not only the current biologic therapies, but also novel drug targets are discussed. Therapeutic targeting of B regulatory cells, T regulatory cells, as well as the immunomodulation effects of nanoparticles and organisms are also covered, along with our understanding and future challenges of prognostic significance of treatments in autoimmune diseases.

Advances in Immunology, Volume 125 (Hardcover): Frederick W. Alt Advances in Immunology, Volume 125 (Hardcover)
Frederick W. Alt
R5,292 R4,430 Discovery Miles 44 300 Save R862 (16%) Ships in 12 - 19 working days

Advances in Immunology, a long-established and highly respected publication, presents current developments as well as comprehensive reviews in immunology. Articles address the wide range of topics that comprise immunology, including molecular and cellular activation mechanisms, phylogeny and molecular evolution, and clinical modalities. Edited and authored by the foremost scientists in the field, each volume provides up-to-date information and directions for the future.

Immunology - At a Glance (Hardcover): S. Nandi Immunology - At a Glance (Hardcover)
S. Nandi
R1,559 Discovery Miles 15 590 Ships in 12 - 19 working days

The book is written in a very simple and lucid manner so that everybody can read and understand the Immunology subject very easily. The book is useful for scientist, teachers, students, officers, diagnosticians and researchers as Immunology has become an essential and indispensable subject now a days not only to understand the different arms of the immune system playing a role in the pathogenesis of the diseases but also to diagnose and treat the diseases in a efficient and effective manner. This book will provide information on all the aspects of the Immunology such as Elements of innate and acquired immunity, Antigens and antigenicity, Antibody structure and functions, Complement, Serological tests, origin, morphology and functions of T and B lymphocytes, Cytokines, Defects in immune system, AIDS, Autoimmunity and tolerance, Tumour immunology, Vaccines and vaccinations besides a large number of questions of miscellaneous nature. A list of tests recommended for infectious diseases in international trade has also been included for ready reference of researchers, teachers and students as well. Lastly it will be helpful for all to understand the Immunology subject easily and to face various competitive examinations with a greater degree of confidence.

Immunogenetics: A Molecular and Clinical Overview - A Molecular Approach to Immunogenetics (Paperback): Muneeb U Rehman, Azher... Immunogenetics: A Molecular and Clinical Overview - A Molecular Approach to Immunogenetics (Paperback)
Muneeb U Rehman, Azher Arafah, Md. Niamat Ali, Shafat Ali
R3,716 Discovery Miles 37 160 Ships in 12 - 19 working days

A Molecular Approach to Immunogenetics, Immunogenetics: A Molecular and Clinical Overview, Volume One provides readers with an exclusive, updated overview on the scientific knowledge, achievements and findings in the field of immunogenetics. The book presents readily available, updated information on the molecular and clinical aspects of immunogenetics, from origin and development to clinical applications and future prospects. The breadth of information goes from basics to developments, clinical applications and future prospects. The book's most attractive attribute is its academic and clinical amalgamation that covers both the theoretical and practical aspects of immunogenetics. An additional feature of the book is a special chapter on viral genetics that covers COVID-19. Above all, the book contains chapters that discuss immunogenetics in relation to pharmaco-genomics and immune-toxicology.

Translational Studies on Inflammation (Hardcover): Ane C.F. Nunes Translational Studies on Inflammation (Hardcover)
Ane C.F. Nunes
R3,360 Discovery Miles 33 600 Ships in 10 - 15 working days
Introductory Immunology - Basic Concepts for Interdisciplinary Applications (Paperback): Jeffrey Actor Introductory Immunology - Basic Concepts for Interdisciplinary Applications (Paperback)
Jeffrey Actor
R1,182 Discovery Miles 11 820 Ships in 12 - 19 working days

"Introductory Immunology" quickly acquaints readers with natural immune responses manifesting in diseases and disorders. The book presents a complete picture of natural defenses to infectious agents, as well as the mechanisms that lead to autoimmune dysfunction. In addition, it examines immunologically based diseases, giving the reader sufficient knowledge to make sound clinical decisions leading to better treatment outcomes.

"Introductory Immunology" is aimed at researchers, postgraduates, or any scientifically inclined reader interested in immunology. No prior expertise in medical, biochemical, or cellular science is needed to benefit from the clear presentation of immunology concepts in this book.
Quick, concise introduction to immunological conceptsBreaks down all of immunology into manageable, logically digestible building blocksGeared toward readers without medical, biochemical, or cellular expertise

Translational Autoimmunity, Volume 1 - Etiology of Autoimmune Diseases (Paperback): Nima Rezaei Translational Autoimmunity, Volume 1 - Etiology of Autoimmune Diseases (Paperback)
Nima Rezaei; Contributions by Niloufar Yazdanpanah
R3,650 Discovery Miles 36 500 Ships in 12 - 19 working days

Translational Autoimmunity: Etiology of Autoimmune Diseases is the first volume of the Translational Immunology book series. To attain its purpose as a detailed translational step to tackle autoimmunity, this volume sufficiently addresses basic questions on how the immune system is designed to distinguish self from nonself. It discusses the known mechanisms that lead to the maintenance of self-tolerance, presents potential triggers and malfunctions that impede normal immune processes, and demonstrates how the immune system induces an autoreactive state that results in the recognition of self-antigens seen in autoimmune conditions.

Pediatric Immunology and Allergy, An Issue of Immunology and Allergy Clinics of North America, Volume 41-4 (Hardcover):... Pediatric Immunology and Allergy, An Issue of Immunology and Allergy Clinics of North America, Volume 41-4 (Hardcover)
Elizabeth Secord
R2,153 Discovery Miles 21 530 Ships in 12 - 19 working days

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