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Books > Medicine > Clinical & internal medicine > Diseases & disorders > Immunology > General

Structure, Function and Regulation of TOR complexes from Yeasts to Mammals, Volume 27 - Part A (Hardcover, 27th edition):... Structure, Function and Regulation of TOR complexes from Yeasts to Mammals, Volume 27 - Part A (Hardcover, 27th edition)
Michael N. Hall, Fuyuhiko Tamanoi
R3,412 Discovery Miles 34 120 Ships in 12 - 17 working days

Cell growth is highly regulated and is controlled by the TOR signaling network. Dysfunction of signaling pathways controlling cell growth results in cells of altered sizes and in turn causes developmental errors and a wide range of pathological conditions. An understanding of the TOR signaling network may lead to novel drugs for the treatment of, for example, cancer, diabetes, inflammation, muscle atrophy, learning disabilities, depression, obesity and aging.

There has been an explosion of knowledge in this area in recent years and this volume provides an in-depth review of our current knowledge of TOR complexes by the leaders in the field.
* Contributions from leading authorities
* Informs and updates on all the latest developments in the field

Novartis Foundation Symposium 238 - Gastroenteritis Viruses (Hardcover): Novartis Novartis Foundation Symposium 238 - Gastroenteritis Viruses (Hardcover)
Novartis
R2,807 Discovery Miles 28 070 Ships in 12 - 17 working days

Gastroenteritis viruses are a major cause of morbidity and mortality in humans. Many hundreds of thousands of children die annually from rotavirus diarrhoea in the developing world, and although in industrialized countries rotavieus infection is rarely fatal, the economic burden of the disease is substantial. Human caliciviruses have emerged as a significant cause of viral gastroenteritis globally. This book contains presentations and discussions by internationally recognized experts on virus structure, replication, pathogenesis, immune response and correlates of protection, molecular-epidemiological surveillance, advances in treatment, and efforts to develop vaccines, particularly against rotavirus disease. The spectrum of viruses covered comprises rotaviruses, human caliciviruses, astroviruses, coronaviruses and viruses causing gut disease in the immunocompromized host. The book not only conveys facts but also gives ample room to lively discussions on many issues at the forefront of research and development.

Advances in Immunology, Volume 102 (Hardcover, 102nd edition): Frederick W. Alt Advances in Immunology, Volume 102 (Hardcover, 102nd edition)
Frederick W. Alt
R4,354 Discovery Miles 43 540 Ships in 12 - 17 working days

"Advances in Immunology, " a long-established and highly respected publication, presents current developments as well as comprehensive reviews in immunology. Articles address the wide range of topics that comprise immunology, including molecular and cellular activation mechanisms, phylogeny and molecular evolution, and clinical modalities. Edited and authored by the foremost scientists in the field, each volume provides up-to-date information and directions for future.
* Contributions from leading authorities and industry experts
* Informs and updates on all the latest developments in the field

Chemokines, Part B, Volume 461 (Hardcover, 462nd edition): Tracy Handel, Damon Hamel Chemokines, Part B, Volume 461 (Hardcover, 462nd edition)
Tracy Handel, Damon Hamel
R5,032 Discovery Miles 50 320 Ships in 12 - 17 working days

The understanding of chemokines, the proteins that control the migration of cells, and their receptors, is critical to the study of causes and therapies for a wide range of human diseases and infections, including certain types of cancer, inflammatory diseases, HIV, and malaria. This volume, focusing on chemokine structure and function, as well as signaling, and its companion volume ("Methods in Enzymology" volume 461, focusing on chemokines as potential targets for disease intervention) provide a comprehensive overview and time-tested protocols in this field, making it an essential reference for researchers in the area.
Along with its companion volume, provides a comprehensive overview of chemokine methods, specifically as related to potential disease therapy
Gathers tried, tested, and trusted methods and techniques from top players in chemokine research
Provides an essential reference for researchers in the field

Chemokines, Part A, Volume 460 (Hardcover, 461st edition): Tracy Handel, Damon Hamel Chemokines, Part A, Volume 460 (Hardcover, 461st edition)
Tracy Handel, Damon Hamel
R5,036 Discovery Miles 50 360 Ships in 12 - 17 working days

The understanding of chemokines, the proteins that control the migration of cells, and their receptors, is critical to the study of causes and therapies for a wide range of human diseases and infections, including certain types of cancer, inflammatory diseases, HIV, and malaria. This volume, focusing on chemokines as potential targets for disease intervention, and its companion volume ("Methods in Enzymology" volume 462, focusing on chemokine structure and function, as well as signaling) provide a comprehensive overview and time-tested protocols in this field, making it an essential reference for researchers in the area.
Along with its companion volume, provides a comprehensive overview of chemokine methods, specifically as related to potential disease therapy
Gathers tried, tested, and trusted methods and techniques from top players in chemokine research
Provides an essential reference for researchers in the field

Mims' Medical Microbiology and Immunology (Paperback, 6th edition): Richard Goering, Hazel Dockrell, Mark Zuckerman, Peter... Mims' Medical Microbiology and Immunology (Paperback, 6th edition)
Richard Goering, Hazel Dockrell, Mark Zuckerman, Peter L Chiodini
R2,013 Discovery Miles 20 130 Ships in 12 - 17 working days

Learn all the microbiology and basic immunology concepts you need to know for your courses and exams. Now fully revised and updated, Mims' clinically relevant, systems-based approach and abundant colour illustrations make this complex subject easy to understand and remember. Learn about infections in the context of major body systems and understand why these are environments in which microbes can establish themselves, flourish, and give rise to pathologic changes. This systems-based approach to microbiology employs integrated and case-based teaching that places the 'bug parade' into a clinical context. Effectively review for problem-based courses with the help of chapter introductions and 'Lessons in Microbiology' text boxes that highlight the clinical relevance of the material, offer easy access to key concepts, and provide valuable review tools. Approach microbiology by body system or by pathogen through the accompanying electronic 'Pathogen Parade' - a quickly searchable, cross-referenced glossary of viruses, bacteria and fungi A new electronic 'Vaccine Parade' offers quick-reference coverage of the most commonly used vaccines in current clinical practice Deepen your understanding of epidemiology and the important role it plays in providing evidence-based identification of key risk factors for disease and targets for preventative medicine. Grasp and retain vital concepts easily, with a user-friendly colour coded format, succinct text, key concept boxes, and dynamic illustrations. New and enhanced information reflects the growing importance of the human microbiota and latest molecular approaches Access the complete contents on the go via the accompanying interactive eBook, with a range of bonus materials to enhance learning and retention - includes self-assessment materials and clinical cases to check your understanding and aid exam preparation.

Advances in Immunology, Volume 101 (Hardcover, 101st edition): Frederick W. Alt Advances in Immunology, Volume 101 (Hardcover, 101st edition)
Frederick W. Alt
R4,348 Discovery Miles 43 480 Ships in 12 - 17 working days

"Advances in Immunology, " a long-established and highly respected publication, presents current developments as well as comprehensive reviews in immunology. Articles address the wide range of topics that comprise immunology, including molecular and cellular activation mechanisms, phylogeny and molecular evolution, and clinical modalities. Edited and authored by the foremost scientists in the field, each volume provides up-to-date information and directions for future research.
* Contributions from leading authorities and industry experts
* Informs and updates on all the latest developments in the field

Advances in Immunology, Volume 98 (Hardcover): Frederick W. Alt Advances in Immunology, Volume 98 (Hardcover)
Frederick W. Alt
R4,347 Discovery Miles 43 470 Ships in 12 - 17 working days

Advances in Immunology, a long-established and highly respected publication, presents current developments as well as comprehensive reviews in immunology. Articles address the wide range of topics that comprise immunology, including molecular and cellular activation mechanisms, phylogeny and molecular evolution, and clinical modalities. Edited and authored by the foremost scientists in the field, each volume provides up-to-date information and directions for future research.
* Contributions from leading authorities and industry experts
* Informs and updates on all the latest developments in the field
* Reference and guide for scientists and specialists involved in advancements in immunology

Dynamics of Immune Activation in Viral Diseases (Hardcover, 1st ed. 2020): Pallaval Veera Bramhachari Dynamics of Immune Activation in Viral Diseases (Hardcover, 1st ed. 2020)
Pallaval Veera Bramhachari
R5,184 Discovery Miles 51 840 Ships in 10 - 15 working days

This book discusses various components of the innate and adaptive immune response in combating viral infections, presenting the recent advances in our understanding of innate immunity recognition of viruses and highlighting the important role of inflammation, cytokines such as interferon, toll-like receptors and leukocytes in the initial detection of invading viruses and subsequent activation of adaptive immunity. It also summarizes the role of the adaptive immunity against viral infections through clearance of virus and establishment of memory response that protects against the recurrent infections. In addition, the book examines the role of DNA and RNA sensors in viral recognition and in controlling viral infection. Lastly, it reviews the latest developments in the development of the rational viral vaccines. As such it is a useful resource book for postgraduate and early researchers wanting to gain insights into the immune response to viral infections.

Advances in Immunology, Volume 97 (Hardcover): Frederick W. Alt Advances in Immunology, Volume 97 (Hardcover)
Frederick W. Alt
R4,350 Discovery Miles 43 500 Ships in 12 - 17 working days

"Advances in Immunology," a long-established and highly respected publication, presents current developments as well as comprehensive reviews in immunology. Articles address the wide range of topics that comprise immunology, including molecular and cellular activation mechanisms, phylogeny and molecular evolution, and clinical modalities. Edited and authored by the foremost scientists in the field, each volume provides up-to-date information and directions for future research.

Stromal Signaling in Cancer, Volume 154 (Hardcover): Peggi Angel, Michael Ostrowski Stromal Signaling in Cancer, Volume 154 (Hardcover)
Peggi Angel, Michael Ostrowski
R3,834 Discovery Miles 38 340 Ships in 12 - 17 working days

Stromal Signaling in Cancer, Volume 154 in the Advances in Cancer Research series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics surrounding cancer research. Each chapter is written by an international board of authors.

Advances in Immunology, Volume 153 (Hardcover): Frederick W. Alt, Kenneth M. Murphy Advances in Immunology, Volume 153 (Hardcover)
Frederick W. Alt, Kenneth M. Murphy
R4,328 Discovery Miles 43 280 Ships in 12 - 17 working days

Advances in Immunology, Volume 153, the latest release in a long-established and highly respected publication, presents current developments and comprehensive reviews in immunology, with this volume covering Regulatory T Cells in Infection and Factor H and Properdin and their regulation.

Pediatrics in Systemic Autoimmune Diseases, Volume 11 (Hardcover, 6th edition): Rolando Cimaz, Thomas J. A Lehman Pediatrics in Systemic Autoimmune Diseases, Volume 11 (Hardcover, 6th edition)
Rolando Cimaz, Thomas J. A Lehman; Series edited by Ronald A. Asherson
R4,013 Discovery Miles 40 130 Ships in 12 - 17 working days

Many of the systemic autoimmune diseases seen in children are different from those seen in adults making them a special problem for physicians and scientists who care for the affected children and study their diseases. Benefiting both pediatric and adult rheumatologists, as well as physicians from other specialties, this volume covers the latest advances in pathogenesis and clinical management of common conditions seen in pediatric rheumatology practices.

Advances in Immunology, Volume 96 (Hardcover, 96th edition): Frederick W. Alt Advances in Immunology, Volume 96 (Hardcover, 96th edition)
Frederick W. Alt
R4,344 Discovery Miles 43 440 Ships in 12 - 17 working days

Advances in Immunology, a long-established and highly respected publication, presents current developments as well as comprehensive reviews in immunology. Articles address the wide range of topics that comprise immunology, including molecular and cellular activation mechanisms, phylogeny and molecular evolution, and clinical modalities. Edited and authored by the foremost scientists in the field, each volume provides up-to-date information and directions for future research.

Advances in Immunology, Volume 95 (Hardcover, 95th edition): Frederick W. Alt Advances in Immunology, Volume 95 (Hardcover, 95th edition)
Frederick W. Alt
R4,353 Discovery Miles 43 530 Ships in 12 - 17 working days

Advances in Immunology, a long established and highly respected publication, presents current developments as well as comprehensive reviews in immunology. Articles address the wide range of topics that comprise immunology, including molecular and cellular activation mechanisms, phylogeny and molecular evolution, and clinical modalities. Edited and authored by the foremost scientists in the field, each volume provides up-to-date information and directions for future research.

Cell Reprogramming for Immunotherapy - Methods and Protocols (Hardcover, 1st ed. 2020): Samuel G. Katz, Peter M. Rabinovich Cell Reprogramming for Immunotherapy - Methods and Protocols (Hardcover, 1st ed. 2020)
Samuel G. Katz, Peter M. Rabinovich
R5,710 Discovery Miles 57 100 Ships in 10 - 15 working days

This volume details key protocols for developing strategies in immunotherapy. Chapters guide the readers through protocols related to various DNA, RNA and protein methods to reprogram the immune system, immune cells, analyzing the effect of the reprogrammed cells, and key methods to consider and analyze patients enrolled in clinical trials with novel immunotherapy regimens. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Cell Reprogramming for Immunotherapy: Methods and Protocols aims to ensure successful results in the further study of this vital field.

AID for Immunoglobulin Diversity, Volume 94 (Hardcover, 94th edition): Frederick W. Alt AID for Immunoglobulin Diversity, Volume 94 (Hardcover, 94th edition)
Frederick W. Alt; Edited by (ghost editors) Tasuku Honjo
R4,360 Discovery Miles 43 600 Ships in 12 - 17 working days

Advances in Immunology, a long established and highly respected serial, presents current developments as well as comprehensive reviews in immunology. Articles address the wide range of topics that comprise immunology, including molecular and cellular activation mechanisms, phylogeny and molecular evolution, and clinical modalities. Edited and authored by the foremost scientists in the field, each volume provides up-to-date information and directions for future research.

Advances in Immunology, Volume 93 (Hardcover, 93rd edition): Frederick W. Alt Advances in Immunology, Volume 93 (Hardcover, 93rd edition)
Frederick W. Alt
R4,354 Discovery Miles 43 540 Ships in 12 - 17 working days

Advances in Immunology, a long established and highly respected serial, presents current developments as well as comprehensive reviews in immunology. Articles address the wide range of topics that comprise immunology, including molecular and cellular activation mechanisms, phylogeny and molecular evolution, and clinical modalities. Edited and authored by the foremost scientists in the field, each volume provides up-to-date information and directions for future research.

The Mouse in Biomedical Research, Volume 4 - Immunology (Hardcover, 2nd edition): James G. Fox, Stephen Barthold, Muriel... The Mouse in Biomedical Research, Volume 4 - Immunology (Hardcover, 2nd edition)
James G. Fox, Stephen Barthold, Muriel Davisson, Christian E. Newcomer, Fred W Quimby, …
R2,896 Discovery Miles 28 960 Ships in 12 - 17 working days

Immunology, the third volume in the four volume set, The Mouse in Biomedical Research, is a completely new addition to this series, dedicated to mouse immunology. It is based on the vast body of knowledge which has made the mouse the model of choice when studying immunity in man. Arguably more is known about the immune system in mice than any other species except man. In large part this is due to the power of genetic engineering to delineate molecular mechanisms. In this volume we present an Overview to mouse immunology, including both the innate and adaptive immune systems, followed by 15 chapters, each dealing with a specific area of immunology in the mouse. These chapters illustrate the power of genetic engineering in dissecting each component of the immune response from the development of lymphoid tissues to signal transduction pathways in activated cells.

Advances in Immunology, Volume 92 (Hardcover, 92nd edition): Frederick W. Alt Advances in Immunology, Volume 92 (Hardcover, 92nd edition)
Frederick W. Alt
R4,362 Discovery Miles 43 620 Ships in 12 - 17 working days

Advances in Immunology, a long established and highly respected publication, presents current developments as well as comprehensive reviews in immunology. Articles address the wide range of topics that comprise immunology, including molecular and cellular activation mechanisms, phylogeny and molecular evolution, and clinical modalities. Edited and authored by the foremost scientists in the field, each volume provides up-to-date information and directions for future research.

Advances in Immunology, Volume 151 (Hardcover): Frederick W. Alt Advances in Immunology, Volume 151 (Hardcover)
Frederick W. Alt
R4,839 Discovery Miles 48 390 Ships in 12 - 17 working days

Advances in Immunology, Volume 151, the latest release in a long-established and highly respected publication, presents current developments and comprehensive reviews in immunology.

Immunotherapy - Activation, Suppression & Treatments (Hardcover): Blake C. Facinelli Immunotherapy - Activation, Suppression & Treatments (Hardcover)
Blake C. Facinelli
R4,538 Discovery Miles 45 380 Ships in 12 - 17 working days

Immunotherapy is a medical term defined as 'treatment of disease by inducing, enhancing, or suppressing an immune response'. Immunotherapies are designed to elicit or amplify an immune response and are classified as activation immunotherapies. Immunotherapies designed to reduce, suppress or more appropriately to direct an existing immune response, as in cases of autoimmunity or allergy, are classified as suppression immunotherapies. This book presents topical data on immunotherapies including antifungal immunotherapy, active and specific immunotherapeutical strategies for the prevention and treatment of cancer, allergen immunotherapy, dendritic cell/tumour fusion cell vaccine in cancer therapy, CRLA-4 inhibition in malignant melanoma, and, others.

Your Best Immunity - Build Resistance the Ace Way (Paperback): Dr John Tickell Your Best Immunity - Build Resistance the Ace Way (Paperback)
Dr John Tickell
R413 Discovery Miles 4 130 Ships in 12 - 17 working days
Exercise Immunology (Paperback, New): Michael Gleeson, Nicolette Bishop, Neil Walsh Exercise Immunology (Paperback, New)
Michael Gleeson, Nicolette Bishop, Neil Walsh
R2,235 Discovery Miles 22 350 Ships in 12 - 17 working days

Exercise immunology is an important, emerging sub-discipline within exercise physiology, concerned with the relationship between exercise, immune function and infection risk. This book offers a comprehensive, up-to-date and evidence-based introduction to exercise immunology, including the physiological and molecular mechanisms that determine immune function and the implications for health and performance in sport and everyday life. Written by a team of leading exercise physiologists, the book describes the characteristics of the immune system and how its components are organised to form an immune response. It explains the physiological basis of the relationship between stress, physical activity, immune function and infection risk, and identifies the ways in which exercise and nutrition interact with immune function in athletes and non-athletes. The book shows students how to evaluate the strengths and limitations of the evidence linking physical activity, immune system integrity and health, and explains why exercise is associated with anti-inflammatory effects that are potentially beneficial to long-term health. Every chapter includes useful features, such as clear summaries, definitions of key terms, discussions of seminal research studies and practical guidelines for athletes on ways to minimise infection risk, with additional learning resources available on a companion website. This is an essential textbook for any course on exercise immunology or advanced exercise physiology.

Microglia - Methods and Protocols (Hardcover, 1st ed. 2019): Olga Garaschuk, Alexei Verkhratsky Microglia - Methods and Protocols (Hardcover, 1st ed. 2019)
Olga Garaschuk, Alexei Verkhratsky
R5,211 Discovery Miles 52 110 Ships in 10 - 15 working days

This book presents a comprehensive toolkit of versatile techniques for studying microglia under different experimental settings along with a brief summary of knowledge, accumulated in microglial research over the last decades. Beginning with recently discovered roles of microglia in health and disease, the volume continues by covering in vitro analyses of microglia, in vivo studies, and "omics" analyses. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Microglia: Methods and Protocols serves as a vital guide to these important cells and an inspiration for scientists interested in expanding our knowledge of their role in the nervous system.

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