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Immunobiology of Natural Killer Cell Receptors (Hardcover, 2006 ed.) Loot Price: R4,459
Discovery Miles 44 590
You Save: R1,157 (21%)
Immunobiology of Natural Killer Cell Receptors (Hardcover, 2006 ed.): Eric Vivier, Marco Colonna

Immunobiology of Natural Killer Cell Receptors (Hardcover, 2006 ed.)

Eric Vivier, Marco Colonna

Series: Current Topics in Microbiology and Immunology, 298

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List price R5,616 Loot Price R4,459 Discovery Miles 44 590 | Repayment Terms: R418 pm x 12* You Save R1,157 (21%)

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Natural Killer (NK) cells are large granular lymphocytes of the innate immune system. They are widespread throughout the body, being present in both lymphoid organs and non-lymphoid peripheral tissues. NK cells are involved in direct innate immune reactions against viruses, bacteria, parasites and other triggers of pathology, such as malignant transformation, all of which cause stress in affected cells. Importantly, NK cells also link the innate and adaptive immune responses, contributing to the initiation of adaptive immune responses and executing adaptive responses using the CD16 FcgRIIIA immunoglobulin Fc receptor. Such responses are mediated through two major effector functions, the direct cytolysis of target cells and the production of cytokines and chemokines. The authors focus here on the nature of recognition events by NK cells and address how these events are integrated to trigger these distinct and graded effector functions.

General

Imprint: Springer-Verlag
Country of origin: Germany
Series: Current Topics in Microbiology and Immunology, 298
Release date: October 2005
First published: 2006
Editors: Eric Vivier • Marco Colonna
Dimensions: 235 x 155 x 17mm (L x W x T)
Format: Hardcover
Pages: 284
Edition: 2006 ed.
ISBN-13: 978-3-540-26083-7
Categories: Books > Medicine > Pre-clinical medicine: basic sciences > Physiology > Cellular physiology
Books > Medicine > Clinical & internal medicine > Diseases & disorders > Immunology > General
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LSN: 3-540-26083-8
Barcode: 9783540260837

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