The Atlas of X-Linked Intellectual Disability Syndromes is a comprehensive and up-to-date summary of the clinically distinctive disorders caused by genes on the X chromosome. Clinical and laboratory data on 150 syndromes are presented in a concise and consistent manner. Each syndrome is defined and information is provided on somatic features, growth and development, neurological signs, cognitive performance, imaging and other laboratory findings, and when possible, the nature and localization of the responsible gene. Craniofacial and other somatic findings are extensively illustrated. A differential matrix accompanies each syndrome description to assist the reader in identifying other X-linked syndromes with overlapping features. Individual syndrome entries are supplemented with nineteen appendices that identify syndromes with common features and provide the location or mapping limits and function of the responsible genes. The authors have extensive experience in the clinical and laboratory delineation of X-linked intellectual disability. They have described new syndromes, regionally mapped disease loci on the X chromosome, and identified the genes responsible for X-linked syndromes.

Each volume in the Cornell Wordsworth is complete in itself, but no volume supplied tools useful to anyone studying two or more volumes. In this supplementary volume the reader will find a unified index to titles and first lines for the entire series, a guide to the hundreds of manuscripts treated in the twenty-one volumes, and a comprehensive list of the contents of Wordsworth's many lifetime editions. The chance to provide such tools in a volume supplementary to the series made it possible as well to include information that had been omitted from previous volumes and a list of errata for several volumes in the series.

IN PLAIN SIGHT - SEARCHING FOR A MORE EXCELLENT WAY, addresses the ongoing exodus from western churches. Census records remind us there are two to three times more Christians than go to church. Interestingly, the increase of Christianity in third world countries is remarkable. Western churches are suffering a massive dislocation from both society and from Christianity in general. What is suggested in this book is exactly the sort of process God enables/allows while preparing the next stage of a grand plan in the drama of human redemption. We must search for a more excellent way. "Tolerant Spirit" is paramount in hearing the voice of the Spirit along the spiritual journey. IN PLAIN SIGHT extends the sacred conversation to all fellow travelers aspiring to discover or regain their spiritual compasses in being faithful to a true and living God who rules and reigns beyond our many fallible conceptions of divine governance in the world, and the interaction of divine initiative and human responsibility. The problem of forging a new paradigm in the churches for a new age is a sacred conversation about rethinking divine activity and personal and corporate faithfulness. We must become much more intentional about developing a theology of grace which thoroughly encompasses serious crises and problems of all spiritual pilgrims, travelers, and persons of sincere faith.

Between 2021 and 2031, the UK government is set to spend over £230 billion on its military. Who decides how to use these funds, and how can we be sure that the UK’s armed forces can meet the threats of tomorrow? This book provides the answers to these crucial questions. Concentrating on decisions taken below the political level, it uncovers the factors that underpin the translation of strategic direction into military capability. In a series of interviews, over 30 top admirals, generals and air marshals give their own views on the procurement and maintenance of the nation’s current and future military capability. Their unrivalled professional knowledge and experience affords a fascinating insight into the higher management of national defence.

Based on large database of films depicting epidemics Long-term of cinematic history Demonstrates Societal responses to epidemics "from below" Focuses on epidemic responses down important lines (trust, heroism, gender, inequality)

Originally published in 1982, this book provides rich evidence of the relevance of the temporal aspects of behavior. The generalized areas of learning, memory, operant scheduled behavior, task performance, vigilance, mood and motivation and their rhythmic components are explored in varying detail. The particularized measures range from on-the-job errors, through reading efficiency to milliseconds of change in reaction time in the laboratory. The subjects range from ants to older persons. Across this range of settings, subjects, and behaviors, the message is clear: there is an interaction between time and behavior.

Based on large database of films depicting epidemics Long-term of cinematic history Demonstrates Societal responses to epidemics "from below" Focuses on epidemic responses down important lines (trust, heroism, gender, inequality)

Between 2021 and 2031, the UK government is set to spend over GBP230 billion on its military. Who decides how to use these funds, and how can we be sure that the UK's armed forces can meet the threats of tomorrow? This book provides the answers to these crucial questions. Concentrating on decisions taken below the political level, it uncovers the factors that underpin the translation of strategic direction into military capability. In a series of interviews, over 30 top admirals, generals and air marshals give their own views on the procurement and maintenance of the nation's current and future military capability. Their unrivalled professional knowledge and experience affords a fascinating insight into the higher management of national defence.

Commercial development of cultured-derived food ingredients has attracted interna tional interest. As consumers have become more health conscious in recent years, the de mand for natural food ingredients and disease-preventative phytochemicals has increased tremendously. Plant Cell and Tissue Culture provides an alternative method for controlled production of these products. A wide range of food ingredients has been shown to be pro duced in culture. Much progress has been made in advancing this technology to the point that large-scale production has become possible. This book is developed from the Symposium "Plant Cell and Tissue Culture for Food Ingredient Production" which was held on April 13-17, 1997 at the American Chemical So ciety National Meeting in San Francisco, CA. In this book, international experts in acade mia, government, and industry discuss current advances in the field of plant cell and tissue culture with special emphasis on its application for food ingredient production. Topics re lated to various aspects of plant cell and tissue culture technology are discussed, including overviews of recent advances in plant metabolic pathway studies, process development for improving yields, and bioreactor design and operation for large-scale production. Economic considerations and issues related to the commercial development of culture-derived food in gredients are discussed. Also included are the safety assessment schemes and regulatory frameworks set up by regulatory agencies around the world."

Why in the pre-industrial period were some settlements resilient and stable over the long term while other settlements were vulnerable to crisis? Indeed, what made certain human habitations more prone to decline or even total collapse, than others? All pre-industrial societies had to face certain challenges: exogenous environmental hazards such as earthquakes or plagues, economic or political hazards from 'outside' such as warfare or expropriation of property, or hazards of their own-making such as soil erosion or subsistence crises. How then can we explain why some societies were able to overcome or negate these problems, while other societies proved susceptible to failure, as settlements contracted, stagnated, were abandoned, or even disappeared entirely? This book has been stimulated by the questions and hypotheses put forward by a recent 'disaster studies' literature - in particular, by placing the intrinsic arrangement of societies at the forefront of the explanatory framework. Essentially it is suggested that the resilience or vulnerability of habitation has less to do with exogenous crises themselves, but on endogenous societal responses which dictate: (a) the extent of destruction caused by crises and the capacity for society to protect itself; and (b) the capacity to create a sufficient recovery. By empirically testing the explanatory framework on a number of societies between the Middle Ages and the nineteenth century in England, the Low Countries, and Italy, it is ultimately argued in this book that rather than the protective functions of the state or the market, or the implementation of technological innovation or capital investment, the most resilient human habitations in the pre-industrial period were those than displayed an equitable distribution of property and a well-balanced distribution of power between social interest groups. Equitable distributions of power and property were the underlying conditions in pre-industrial societies that all

Originally published in 1982, this book provides rich evidence of the relevance of the temporal aspects of behavior. The generalized areas of learning, memory, operant scheduled behavior, task performance, vigilance, mood and motivation and their rhythmic components are explored in varying detail. The particularized measures range from on-the-job errors, through reading efficiency to milliseconds of change in reaction time in the laboratory. The subjects range from ants to older persons. Across this range of settings, subjects, and behaviors, the message is clear: there is an interaction between time and behavior.

This book presents the first comparative study of the works of Charlotte Delbo, Noor Inayat Khan, and Germaine Tillion in relation to their vigorous struggles against Nazi aggression during World War II and the Holocaust. It illuminates ways in which their early lives conditioned both their political engagements during wartime and their extraordinary literary creations empowered by what Lara R. Curtis refers to as modes of 'writing resistance.' With skillful recourse to a remarkable variety of genres, they offer compelling autobiographical reflections, vivid chronicles of wartime atrocities, eyewitness accounts of victims, and acute perspectives on the political implications of major events. Their sensitive reflections of gendered subjectivity authenticate the myriad voices and visions they capture. In sum, this book highlights the lives and works of three courageous women who were ceaselessly committed to a noble cause during the Holocaust and World War II.

This introductory textbook provides students with a system-level perspective and the tools they need to understand, analyze and design digital systems. Going beyond the design of simple combinational and sequential modules, it shows how such modules are used to build complete systems, reflecting real-world digital design. All the essential topics are covered, including design and analysis of combinational and sequential modules, as well as system timing and synchronization. It also teaches how to write VHDL-2008 HDL in a productive and maintainable style that enables CAD tools to do much of the tedious work. A complete introduction to digital design is given through clear explanations, extensive examples and online VHDL files. The teaching package is completed with lecture slides, labs and a solutions manual for instructors. Assuming no previous digital knowledge, this textbook is ideal for undergraduate digital design courses that will prepare students for modern digital practice.

Fisheries buybacks are an important strategy being implemented globally in the efforts to produce a more sustainable and profitable fisheries industry. "Fisheries Buybacks "provides the reader with an overview of buybacks and the issues surrounding them as well as a synthesis of the literature on this subject of growing importance. Alongside this material are eleven case studies from around the world that look at real life applications of buybacks and its successes and failures. Edited by two leading fisheries economists with chapters contributed by international experts in the field, "Fisheries Buybacks" will be a valuable resource for fisheries managers, economists, researchers, and policy makers for years to come.

Commercial development of cultured-derived food ingredients has attracted interna tional interest. As consumers have become more health conscious in recent years, the de mand for natural food ingredients and disease-preventative phytochemicals has increased tremendously. Plant Cell and Tissue Culture provides an alternative method for controlled production of these products. A wide range of food ingredients has been shown to be pro duced in culture. Much progress has been made in advancing this technology to the point that large-scale production has become possible. This book is developed from the Symposium "Plant Cell and Tissue Culture for Food Ingredient Production" which was held on April 13-17, 1997 at the American Chemical So ciety National Meeting in San Francisco, CA. In this book, international experts in acade mia, government, and industry discuss current advances in the field of plant cell and tissue culture with special emphasis on its application for food ingredient production. Topics re lated to various aspects of plant cell and tissue culture technology are discussed, including overviews of recent advances in plant metabolic pathway studies, process development for improving yields, and bioreactor design and operation for large-scale production. Economic considerations and issues related to the commercial development of culture-derived food in gredients are discussed. Also included are the safety assessment schemes and regulatory frameworks set up by regulatory agencies around the world.

This collection of papers is presented to Sir JOHN ECCLES by his former and present collaborators to commemorate the award of the 1963 Nobel Prize in Medicine, which was shared with A. L. HODGKIN and A. F. HUXLEY. Sir JOHN'S interest in, and influence on, the study of physiology, particularly that of the nervous system, is reflected by the range of topics discussed, and by the distri bution of the various authors in laboratories throughout the world. Those who have been privileged to work with him in Oxford, Sydney, Dunedin or Canberra have enjoyed a good discipline in scientific thought, as well as in the use of neurophysiological techniques. Basic knowledge is always transferable, and the inspiration which comes from association with a great scientist is not confined to anyone field of physiology. The contributors to this volume were requested to review briefly that aspect of physiology of current interest to them, and it is hoped that the resulting papers will serve as an up to date review of many physiological problems. The editors are greatly indebted to the publishers, Springer-Verlag, particu larly to Dr. H. GOTZE for his advice and interest. It is also a pleasure to thank Mrs. H. WALSH for her unfailing assistance during the preparation of this book. Canberra Melbourne 1965. III CONTENTS Rhythmic thalamic activity. P. Andersen."

Destinations rely on regional strategies to support and enhance the tourism product through regional partnerships and integration. Integrated tourism is defined as tourism that is explicitly linked to the economic, social, cultural, natural and human structures of the region in which it occurs. Integrated tourism has evolved to include numerous meanings and definitions, but generally includes a vertical business or industry approach. The first of its kind, this book applies a more inclusive approach to integration by providing insight into inclusive regional development strategies that support both the needs of urban and rural areas whilst enhancing the tourist experience, supporting the positive impacts of tourism and mitigating the negative. Regional studies tend to portray either an urban or rural focus without acknowledging that often these spaces constitute joint governance structures, similar historical and cultural roots, and economic dependencies. Sustainable tourism promotes sourcing locally, such as using rural agricultural products in urban tourism experiences. Furthermore, innovative rural marketing strategies linking tourism heritage, attractions, food and drink trails, and artisans with urban visitors are emerging. Including theoretical and applied research and international case studies, this will be a valuable resource to academics, students and practitioners working in tourism development and regional policy.

This book presents the first comparative study of the works of Charlotte Delbo, Noor Inayat Khan, and Germaine Tillion in relation to their vigorous struggles against Nazi aggression during World War II and the Holocaust. It illuminates ways in which their early lives conditioned both their political engagements during wartime and their extraordinary literary creations empowered by what Lara R. Curtis refers to as modes of 'writing resistance.' With skillful recourse to a remarkable variety of genres, they offer compelling autobiographical reflections, vivid chronicles of wartime atrocities, eyewitness accounts of victims, and acute perspectives on the political implications of major events. Their sensitive reflections of gendered subjectivity authenticate the myriad voices and visions they capture. In sum, this book highlights the lives and works of three courageous women who were ceaselessly committed to a noble cause during the Holocaust and World War II.

Disasters and History offers the first comprehensive historical overview of hazards and disasters. Drawing on a range of case studies, including the Black Death, the Lisbon earthquake of 1755 and the Fukushima disaster, the authors examine how societies dealt with shocks and hazards and their potentially disastrous outcomes. They reveal the ways in which the consequences and outcomes of these disasters varied widely not only between societies but also within the same societies according to social groups, ethnicity and gender. They also demonstrate how studying past disasters, including earthquakes, droughts, floods and epidemics, can provide a lens through which to understand the social, economic and political functioning of past societies and reveal features of a society which may otherwise remain hidden from view. This title is also available as Open Access on Cambridge Core.

Disasters and History offers the first comprehensive historical overview of hazards and disasters. Drawing on a range of case studies, including the Black Death, the Lisbon earthquake of 1755 and the Fukushima disaster, the authors examine how societies dealt with shocks and hazards and their potentially disastrous outcomes. They reveal the ways in which the consequences and outcomes of these disasters varied widely not only between societies but also within the same societies according to social groups, ethnicity and gender. They also demonstrate how studying past disasters, including earthquakes, droughts, floods and epidemics, can provide a lens through which to understand the social, economic and political functioning of past societies and reveal features of a society which may otherwise remain hidden from view. This title is also available as Open Access on Cambridge Core.

This introductory textbook provides students with a system-level perspective and the tools they need to understand, analyze and design digital systems. Going beyond the design of simple combinational and sequential modules, it shows how such modules are used to build complete systems, reflecting real-world digital design. All the essential topics are covered, including design and analysis of combinational and sequential modules, as well as system timing and synchronization. It also teaches how to write Verilog HDL in a productive and maintainable style that enables CAD tools to do much of the tedious work. A complete introduction to digital design is given through clear explanations, extensive examples and online Verilog files. The teaching package is completed with lecture slides, labs and a solutions manual for instructors. Assuming no previous digital knowledge, this textbook is ideal for undergraduate digital design courses that will prepare students for modern digital practice.