|
Showing 1 - 12 of
12 matches in All Departments
Microbiome Therapeutics: Personalized Therapy Beyond Conventional
Approaches addresses the current knowledge and landscape of
microbiome therapeutics, providing an overview of existing
applications in health and disease as well as potential future
directions of microbiome modulations and subsequent translation to
the global industry and market. This important reference provides
the most current status of microbiome therapeutics as well as
possible future perspectives through coverage of topics including
the application of microbiome therapeutics; various additive,
subtractive and modulatory approaches; microbiome composition of
health and diseases, insights into live bio-therapeutics and the
clinical data supporting their efficacy. Case studies are provided
throughout the book to further define, describe and evaluate
microbiome therapeutics success and failure.
The book will provide a fundamental understanding of engineering
properties of agricultural produce and the knowledge of engineering
properties are combined with agriculture. Each chapter in the book
will be helpful for the students to understand the relationship
between engineering properties of raw, semi-finished and processed
food to obtain products with desired shelf-life and quality. This
book discusses basic definitions, principles of engineering
properties and their measurement methods with research findings. It
will be helpful to the students for their self-study and to gain
information how to analyze experimental data to generate practical
information. It will also be helpful for students who deal with
engineering properties in their research. Methods to measure these
properties are also explained in details. Note: T& F does not
sell or distribute the Hardback in India, Pakistan, Nepal, Bhutan,
Bangladesh and Sri Lanka. This title is co-published with New India
Publishing Agency.
Adopt an effortless approach to avoid the hassles of complex
concurrency and scaling patterns when building distributed
applications in .NET Key Features Explore the Orleans
cross-platform framework for building robust, scalable, and
distributed applications Handle concurrency, fault tolerance, and
resource management without complex programming patterns Work with
essential components such as grains and silos to write scalable
programs with ease Book DescriptionBuilding distributed
applications in this modern era can be a tedious task as customers
expect high availability, high performance, and improved
resilience. With the help of this book, you'll discover how you can
harness the power of Microsoft Orleans to build impressive
distributed applications. Distributed .NET with Microsoft Orleans
will demonstrate how to leverage Orleans to build highly scalable
distributed applications step by step in the least possible time
and with minimum effort. You'll explore some of the key concepts of
Microsoft Orleans, including the Orleans programming model,
runtime, virtual actors, hosting, and deployment. As you advance,
you'll become well-versed with important Orleans assets such as
grains, silos, timers, and persistence. Throughout the book, you'll
create a distributed application by adding key components to the
application as you progress through each chapter and explore them
in detail. By the end of this book, you'll have developed the
confidence and skills required to build distributed applications
using Microsoft Orleans and deploy them in Microsoft Azure. What
you will learn Get to grips with the different cloud architecture
patterns that can be leveraged for building distributed
applications Manage state and build a custom storage provider
Explore Orleans key design patterns and understand when to reuse
them Work with different classes that are created by code
generators in the Orleans framework Write unit tests for Orleans
grains and silos and create mocks for different parts of the system
Overcome traditional challenges of latency and scalability while
building distributed applications Who this book is forThis book is
for .NET developers and software architects looking for a
simplified guide for creating distributed applications, without
worrying about complex programming patterns. Intermediate web
developers who want to build highly scalable distributed
applications will also find this book useful. A basic understanding
of .NET Classic or .NET Core with C# and Azure will be helpful.
A comprehensive guide to every important component of C# and .NET 6
required to build robust enterprise web applications Key Features *
Explore the advanced features of C# and .NET 6 to enhance your code
and productivity * Follow clear and easy instructions for building
an end-to-end enterprise application * Learn how to build scalable
web applications and host them on the cloud Book Description
Building production-ready enterprise applications can be a
challenging task due to the overabundance of tools and their
different versions that make app development complex. This book
simplifies the process with an end-to-end road map for building
enterprise applications from scratch using the latest features of
.NET Core 6 and C# 10. Throughout the book, you'll work on creating
an enterprise app, adding a key component to the app with each
chapter, before ?nally getting it ready for testing and deployment.
You'll learn concepts relating to advanced data structures, the
Entity Framework Core, parallel programming, and dependency
injection. As you progress, you'll cover various authentication and
authorization schemes provided by .NET Core to make your apps and
APIs secure. The book then shows you how the latest Microsoft
Visual Studio and C# 10 help you simplify developer tasks and
shares tips and tricks in Visual Studio to improve your
productivity. You'll discover various testing techniques, such as
unit testing and performance testing, as well as di?erent methods
to deploy enterprise apps. By the end of this book, you'll be able
to create enterprise apps using the powerful features of .NET 6 and
deploy them to the cloud while working with various cloud
components using Azure. What you will learn * Design enterprise
apps by making the most of the latest features of .NET 6 * Discover
di?erent layers of an app, such as the data layer, API layer, and
web layer * Explore end-to-end architecture by implementing an
enterprise web app using .NET and C# 10 and deploying it on Azure *
Focus on the core concepts of web application development and
implement them in .NET 6 * Integrate the new .NET 6 health and
performance check APIs into your app * Explore MAUI and build an
application targeting multiple platforms - Android, iOS, and
Windows Who This Book Is For If you are a developer, architect, or
senior programmer, this book will show you how to leverage the
features of .NET 6 and the C# language, as well as help you grasp
essential techniques to build your skills.
Become a professional .NET developer by learning expert techniques
for building enterprise-grade applications Key Features Explore the
advanced features of C# and .NET 5 to enhance your code and
productivity Follow clear and easy instructions for building an
end-to-end enterprise application Learn how to build scalable web
applications and host them on the cloud Book Description.NET Core
is one of the most popular programming platforms in the world for
an increasingly large community of developers thanks to its
excellent cross-platform support. This book will show you how to
confidently use the features of .NET 5 with C# 9 to build robust
enterprise applications. Throughout the book, you'll work on
creating an enterprise app and adding a key component to the app
with each chapter, before ?nally getting it ready for testing and
deployment. You'll learn concepts relating to advanced data
structures, the Entity Framework Core, parallel programming, and
dependency injection. As you progress, you'll cover various
authentication and authorization schemes provided by .NET Core to
make your apps and APIs secure. Next, you'll build web apps using
ASP.NET Core 5 and deploy them on the cloud while working with
various cloud components using Azure. The book then shows you how
to use the latest Microsoft Visual Studio 2019 and C# 9 to simplify
developer tasks, and also explores tips and tricks in Visual Studio
2019 to improve your productivity. Later, you'll discover various
testing techniques such as unit testing and performance testing as
well as di?erent methods to deploy enterprise apps. By the end of
this book, you'll be able to create enterprise apps using the
powerful features of .NET 5 and deploy them on the cloud. What you
will learn Design enterprise apps by making the most of the latest
features of .NET 5 Discover di?erent layers of an app, such as the
data layer, API layer, and web layer Explore end-to-end
architecture, implement an enterprise web app using .NET and C# 9,
and deploy the app on Azure Focus on the core concepts of web
application development such as dependency injection, caching,
logging, con?guration, and authentication, and implement them in
.NET 5 Integrate the new .NET 5 health and performance check APIs
with your app Understand how .NET 5 works and contribute to the
.NET 5 platform Who this book is forIf you are a developer,
architect, or senior programmer who wants to leverage the features
of .NET 5 and the C# language, as well as grasp essential
techniques to build your skills, then this C# .NET 5 book is for
you. Beginner to intermediate-level knowledge of the .NET framework
and C# programming is required to understand the concepts covered
in this book more effectively.
Metformin matrix and gastro retentive tablets formulations were
prepared with different compositions. Finally, one optimized
formula for each, matrix and gastro retentive, were selected and
studied in detail. The effect of formulation variables namely,
process of manufacturing, different excipients, different polymers,
and concentration of polymer were studied. Metformin release was
inversely proportional to the polymer concentration. Drug release
from the developed formulations was independent of pH of the
release medium but dependent on the agitational intensity, hardness
of tablet, and surface area of tablet. Metformin release from both
developed matrix and gastro retentive formulations follows first
order. The manufacturing procedure was found to be reproducible and
formulations were stable after one month of accelerated stability
studies.
This study was to investigate the effect of formulation variables
like Microcrystalline cellulose (MCC), Lactose, Dicalcium phosphate
dihydrate (DCPD), Starch 1500, Pearlitol 200sd etc. which are
widely used tabeleting excipients. These diluents were used
individually and in combination with MCC. Binders like
Hydroxypropyl cellulose (HPC-sL), Polyvinylpyrrrolidone-K 30, were
used to study their effect on pellet properties. The pellets
prepared were analyzed for the properties like their shape (aspect
ratio), size distribution, smoothness, bulk density, tapped
density, car index, hausner ratio, Loss on drying and yield.
Amlodipine used as an anti-hypertensive and in the treatment of
angina. FDT of amlodipine besylate were prepared using different
superdisintegrants by direct compression method. Mannitol was used
as a diluent. Aspartame and Acesulfame Potassium were used for
unpleasant taste masked from the amlodipine by cosifting and serial
of blending with other excipients. The mixed final blend was then
compressed into tablets. The formulations were evaluated for weight
variation, hardness, friability, wetting time, disintegrating time,
dissolution, taste evaluation study and in vitro dispersion time.
The objective of this research work was to formulate and evaluate
the floating drug delivery system containing Albendazole, an
anthelmintic drug, using different polymers and to optimize the
best formulation. Different excipients were tested for their
compatibility with Albendazole by the FTIR studies. Present study
has demonstrated the successful utilization of technique of FT IR
to assesst he compatibility of Albendazole with the excipients used
in the development of floating drug delivery system of Albendazole.
Based on the results of FT-IR studies, majority of the excipients
were found to be compatible with Albendazole which were then used
in the preparation of Albendazole floating tablets. Albendazole
tablets were prepared by wet granulation technique using HPMC, HPMC
K4M and chitosan as polymers, stearic acid, citric acid, lactose
and gas generating agent such as sodium bicarbonate were taken as
independent variables. It was then evaluated by using USP-II
(Paddle) apparatus containing 0.1 N HCl as a dissolution media. The
release mechanisms of Albendazole from floating tablet were
evaluated by the n value of Krosmeyer Peppas model.
Fixed Point Theory is a beautiful mixture of analysis (pure and
applied), topology and geometry. Fixed point theorems give the
conditions under which mappings (single or multivalued) have
solutions. The fixed point theory in probabilistic metric spaces is
useful in the study of existence of solutions of operator equations
in probabilistic metric space and probabilistic functional
analysis, which is a very dynamic area of mathematical research.
The notion of a probabilistic metric space corresponds to the
situations when we do not know exactly the distance between two
points; we know only probabilities of possible values of this
distance. This book contains six chapters. New fixed point theorems
for contraction mappings, expansion mappings, probabilistic
densifying mappings are obtained in Menger spaces. Also related
fixed point theorems in Menger spaces and applications of fixed
point theorems are studied. This book will help the researchers
studying fixed point theory.
In this study, controlled release matrix tablets containing
cephelexin were prepared using HPMC15 cps and Eudragit L100 in
different concentration by Direct compression method. Tablets were
evaluated for physical properties, Hardness, friability, weight
variation and In vitro dissolution study was carried on USP II
apparetus (peddle type). The best formulations selected based on
above parameters were subjected for Extend release study with use
of different ratio of polymer as Eudragit and HPMC .The tablets
with Eudragit were found to release drug for longer duration of
time as compared to formulations containing HPMC. The drug release
from the tablets was sufficiently sustained.
In a majority-minority framework, study provides analysis of
various models and approaches adopted by the ruling elite aiming at
nation-building in post-colonial India. Author argues that Sikh
ethno-nationalism was a reaction to/ or the product of flawed and
erroneous approach at nation-forging that was pursued by the people
in power. Neighbouring state Pakistan having hostile relations with
India provided support to the Sikh ethnic uprisings for its own
strategic gains but had no territorial ambitions as are in case of
Kashmir. Moreover, Pakistan was not responsible for the origin of
Sikh ethnic uprisings. It only tried to exploit the situation when
it originated due to the domestic political milieu in India. Sikh
diaspora also participated in its kindred-community's movement
while internationalizing the issue of Khalistan, raising the
question of human rights abuses along with providing diverse types
of moral & material support. Thus, this book is useful for
academicians, statesmen, researchers, students and general readers
to understand the Indian ruling elite's approach at nation-building
in general and Sikh ethno-nationalism in particular.
|
You may like...
Finding Dory
Ellen DeGeneres, Albert Brooks, …
Blu-ray disc
(1)
R42
Discovery Miles 420
|