Early in the Covid-19 pandemic, Salim S. Abdool Karim was catapulted into a prominent position in the media and on television as the face of South African science in the country's response to the pandemic. Up to that point, his groundbreaking research on AIDS had garnered many awards, leading to his recognition as one of the world’s leading epidemiologists, making him ideally positioned to take the scientific lead in the Covid-19 response.

Standing Up for Science is Abdool Karim’s personal, behind-the-scenes account of the first three years of the Covid-19 pandemic. It is inspiring and informative, shedding light on the difficulties in providing scientific advice, on the international co-operation that was integral to responding to the pandemic, as well as giving insight to some of the controversies in the science-to-policy process, and drawing lessons from Covid-19 to prepare for future pandemics.

Beyond the recent events in which the story is grounded, the book is an ode to the value of science and its power to help us tackle some of the world's biggest problems.

This book presents a logical system of critical appraisal, to allow readers to evaluate studies and to carry out their own studies more effectively. This system emphasizes the central importance of cause and effect relationships. Its great strength is that it is applicable to a wide range of issues, and both to intervention trials and observational studies. This system unifies the often different approaches used in epidemiology, health services research, clinical trials, and evidence-based medicine, starting from a logical consideration of cause and effect. The author's approach to the issues of study design, selection of subjects, bias, confounding, and the place of statistical methods has been praised for its clarity and interest. Systematic reviews, meta-analysis, and the applications of this logic to evidence-based medicine, knowledge-based health care, and health practice and policy are discussed. Current and often controversial examples are used, including screening for prostate cancer, publication bias in psychiatry, public health issues in developing countries, and conflicts between observational studies and randomized trials. Statistical issues are explained clearly without complex mathematics, and the most useful methods are summarized in the appendix. The final chapters give six applications of the critical appraisal of major studies: randomized trials of medical treatment and prevention, a prospective and a retrospective cohort study, a small matched case-control study, and a large case-control study. In these chapters, sections of the original papers are reproduced and the original studies placed in context by a summary of current developments.

Stem cell therapy is ushering in a new era of medicine in which we will be able to repair human organs and tissue at their most fundamental level- that of the cell. The power of stem cells to regenerate cells of specific types, such as heart, liver, and muscle, is unique and extraordinary. In 1998 researchers learned how to isolate and culture embryonic stem cells, which are only obtainable through the destruction of human embryos. An ethical debate has raged since then about the ethics of this research, usually pitting pro-life advocates vs. those who see the great promise of curing some of humanity's most persistent diseases.
In this book Cynthia Cohen agrees that we need to work toward a consensus on the issue of how we treat the embryo. But more broadly she claims that we need to transform and expand the ethical and policy debates on stem cells (adult and embryonic). This important and much-needed book is both a primer and a means by which to understand the implications of this research. Cohen starts by introducing readers to the basic science of stem cell research, and the core ethical questions surrounding the embryo. She then expands the scope of the debate, looking at the moral questions that will crop up down the line, such as e.g. the use of therapeutic cloning to overcome the body's immune resistance to stem cells; the ethics of using animals to test stem cells; how to disentangle federal and state legal and regulatory policies in pursuit of a coherent national policy; and how to develop an ethics of stem cell research that will accommodate new techniques and controversies that we cannot even foresee now. Her final chapter develops a concrete plan for an oversight systemfor this research.
This is the first single-author book that addresses the many broad ethical and legal issues related to stem cells, and it should be of great interest to bioethicists, researchers, clinicians, philosophers, theologians, lawyers, policy makers, and general readers.

This book is about pleasure. It's also about pain. Most important, it's about how to find the delicate balance between the two, and why now more than ever finding balance is essential.

We're living in a time of unprecedented access to high-reward, high-dopamine stimuli: drugs, food, news, gambling, shopping, gaming, texting, sexting, Facebooking, Instagramming, YouTubing, tweeting... The increased numbers, variety, and potency is staggering. The smartphone is the modern-day hypodermic needle, delivering digital dopamine 24/7 for a wired generation. As such we've all become vulnerable to compulsive overconsumption.

In Dopamine Nation, Dr. Anna Lembke, psychiatrist and author, explores the exciting new scientific discoveries that explain why the relentless pursuit of pleasure leads to pain...and what to do about it. Condensing complex neuroscience into easy-to-understand metaphors, Lembke illustrates how finding contentment and connectedness means keeping dopamine in check. The lived experiences of her patients are the gripping fabric of her narrative. Their riveting stories of suffering and redemption give us all hope for managing our consumption and transforming our lives. In essence, Dopamine Nation shows that the secret to finding balance is combining the science of desire with the wisdom of recovery.

Includes a 30-Day fasting reset that uses the power of your cycle―even if you no longer have one!

A go-to fasting manual created specifically to address women's needs based on their hormones and menstrual cycle by Dr. Mindy Pelz, a well-known expert on women and fasting, whose fast-growing YouTube channel has become the destination for women who want to learn about fasting.

Are you among the many women who feel unheard and unseen by their doctors and health professionals? Have you become exhausted by the promise of quick-fix diets that only leave you disappointed? Well in Fast Like a Girl, Dr. Mindy helps you to take back control of your health by using the quickest path back to better health―fasting.

While most fasting advice has been a one-size-fits-all approach that leaves women with more questions than answers, in this book Dr. Mindy shares the proven strategies, specific protocols to use if you are trying to overcome a condition, fasting hacks, and tools that she has used to help hundreds of thousands of women thrive with their fasting lifestyles.

Ethical Issues in International Biomedical Research is the definitive book on the ethics of research involving human subjects in developing countries. Using 21 actual case studies, it covers the most controversial topics, including the ethics of placebo research in Africa, what benefits should be provided to the community after completion of a research trial, how to address conflicts between IRBs in developed and developing countries, and undue inducement of poor people in developing countries. Each case is accompanied by two expert commentaries, written by many of the worlds leading experts in bioethics as well as new voices with research experience in developing countries. No other volume has this scope. Students in bioethics, public and international health, and ethics will find this book particularly useful.

Dive into a world of new insights and self-discovery as you unlock the secrets of your subconscious with this collection of 1,000+ common dream symbols and their meanings.

Unlock the mysteries of your dreams with this comprehensive dream dictionary, featuring over 1,000 of the most common dreams and their interpretations. Whether you dream of being underwater, flying, or taking an exam, this handy guide offers insightful and straightforward explanations that illuminate the deeper meanings behind your dreams. Each concise entry will provide you with greater clarity and understanding of yourself and your subconscious thoughts, desires, and fears. Whether you’re a dream enthusiast or a newcomer to dream analysis, this book is your essential companion. Decode the secrets of your dreams and unravel your subconscious with the turn of every page.

GAIN NEW INSIGHTS: Uncover the layers of your subconscious and learn how your dreams reflect your desires, fears, and aspirations, providing you with valuable insights into your waking life.

1,000+ ENTRIES: Entries cover a wide range of the most common dreams, from falling to flying.

EASY TO REFERENCE: Perfect for those new to dream interpretation, with alphabetized entries and simple-to-understand explanations.

EYE-CATCHING DESIGN: In addition to being a practical and comprehensive resource for dream analysis, this dictionary is a high-quality, deluxe product with spot illustrations throughout.

COMPACT AND DURABLE: Durable materials and a portable 5.75" x 8.25" size make this dictionary ideal for taking on overnight trips and fitting on a nightstand.

‘How can there be only one dedicated hospital in the country for our children?’

When Madiba asked this question, he sowed the seeds of a challenge that would grow into a legacy.

A seed may be small but its size is disproportionate to what it can become over time. The Nelson Mandela Children’s Hospital was a project that seemed impossible when it was just an idea that started with ten people seated around a dinner table. As they discussed the state of healthcare in the country and shared their experiences, they realised that it was the children of Southern Africa who were the most disadvantaged by the lack of dedicated paediatric facilities. At the end of the evening a statement by the late Dr Nthato Motlana took hold and became the catalyst for a remarkable journey: ‘I will speak to Nelson,’ he said.

With South Africa’s first democratically elected president Nelson Mandela’s backing, the board of the Children’s Fund was inspired to take up the challenge to address this vital need. After years of global research and advice from experts in numerous different fields a Trust was formed to oversee the project and, critically, to set about raising the one billion rand it would take to build, equip and staff a state-of-the-art children’s hospital.

The stories behind the planning for, fundraising and building of the Nelson Mandela Children’s Hospital are inspiring, personal, and sometimes heart-breaking. It was a long and arduous journey, beset with difficulties, but the dedicated team’s commitment and courage prevailed to create a living legacy that will truly impact the lives of children for generations to come.

Today, the Nelson Mandela Children’s Hospital in Johannesburg is a proud testimony to a uniquely African story which honours the memory of a great statesman and celebrates the children for whom he cared so deeply.

In Death, Dying, and Organ Transplantation: Reconstructing Medical Ethics at the End of Life, Miller and Truog challenge fundamental doctrines of established medical ethics. They argue that the routine practice of stopping life support technology in hospitals causes the death of patients and that donors of vital organs (hearts, lungs, liver, and both kidneys) are not really dead at the time that their organs are removed for life-saving transplantation. These practices are ethically legitimate but are not compatible with traditional rules of medical ethics that doctors must not intentionally cause the death of their patients and that vital organs can be obtained for transplantation only from dead donors.
In this book Miller and Truog undertake an ethical examination that aims to honestly face the reality of medical practices at the end of life. They expose the misconception that stopping life support merely allows patients to die from their medical conditions, and they dispute the accuracy of determining death of hospitalized patients on the basis of a diagnosis of "brain death" prior to vital organ donation. After detailing the factual and conceptual errors surrounding current practices of determining death for the purpose of organ donation, the authors develop a novel ethical account of procuring vital organs. In the context of reasonable plans to withdraw life support, still-living patients are not harmed or wronged by organ donation prior to their death, provided that valid consent has been obtained for stopping treatment and for organ donation.
Recognizing practical difficulties in facing the truth regarding organ donation, the authors also develop a pragmatic alternative account based on the concept of transparent legal fictions. In sum, Miller and Truog argue that in order to preserve the legitimacy of end-of-life practices, we need to reconstruct medical ethics.

Ever since the discovery of blood types early in the last century, transfusion medicine has evolved at a breakneck pace. This second edition of Blood Banking and Transfusion Medicine is exactly what you need to keep up. It combines scientific foundations with today's most practical approaches to the specialty. From blood collection and storage to testing and transfusing blood components, and finally cellular engineering, you'll find coverage here that's second to none. New advances in molecular genetics and the scientific mechanisms underlying the field are also covered, with an emphasis on the clinical implications for treatment. Whether you're new to the field or an old pro, this book belongs in your reference library. Integrates scientific foundations with clinical relevance to more clearly explain the science and its application to clinical practice. Highlights advances in the use of blood products and new methods of disease treatment while providing the most up-to-date information on these fast-moving topics Discusses current clinical controversies, providing an arena for the discussion of sensitive topics. Covers the constantly changing approaches to stem cell transplantation and brings you the latest information on this controversial topic.

The first comprehensive examination of the relationship between war and public health, this book documents the public health consequences of war and describes what health professionals can do to minimise these consequences. It explores the effects of war on health, human rights, and the environment. The health and environmental impact of both conventional weapons and weapons of mass destruction (nuclear, chemical, and biological weapons) is described in chapters that cover the consequences of their production, testing, maintenance, use, and disposal. Separate chapters cover especially vulnerable populations, such as women, children, and refugees. In-depth descriptions of specific military conflicts, including the Vietnam War, the Persian Gulf War, and wars in Central America provide striking illustrations of the issues covered in other chapters. A series of chapters explores the roles of health professionals and of organisations during war, and in preventing war and its consequences. This revised second edition includes seven new chapters, including one on landmines by the Nobel Prize-winning founding director of the International Campaign to Ban Landmines.

Eugenic thought and practice swept the world from the late nineteenth to the mid-twentieth century in a remarkable transnational phenomenon that informed social and scientific policy across the political spectrum, from liberal welfare measures in emerging social-democratic states, to feminist ambitions for birth control, to public health campaigns, to totalitarian dreams of the "perfectibility of man." This book dispels for uninitiated readers the automatic and apparently exclusive link between eugenics and the Holocaust: the popularity of eugenics in Japan, for example, comes as a surprise. It is the first world history of eugenics and an indispensable core text for both teaching and research in what has become a sprawling but ever more important field. Eugenics has accumulated generations of interest as part of the question of how experts think about the connections between biology, human capacity and policy. In the past and the present, eugenics speaks to questions of race, class, gender and sex, evolution, governance, nationalism, disability, and the social implications of science. In the current climate, where the human genome project, stem cell research, and new reproductive technologies have proven so controversial, the history of eugenics has much to teach us about the relationship between scientific research, technology, and human ethical decision-making. This volume offers both a nineteenth-century context for understanding the emergence of eugenics and a consideration of contemporary manifestations of, and relationships to eugenics. It is the definitive text for students and researchers to consult for careful and up-to-date summaries, new substantive fields where very little work is currently available (e.g. eugenics in Iran, South Africa, and South East Asia); transnational thematic lines of inquiry; the integration of literature on colonialism; and connections to contemporary issues.

Proper nutrition is crucial for maintaining one s general health and well-being; with that in mind, you ll discover a wealth of nutritional information within this newly updated and expanded version of our best-selling Nutrition study guide. Each aspect of nutrition from carbohydrates to vitamins is comprehensively examined, with key definitions, examples, charts, and full-color illustrations provided for additional clarity.

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This book is an account of a study which provided unique information on trends in growth and respiratory health in British children over 25 years, with methodological discussion and other major findings including risk factors for impaired growth, obesity, respiratory disease and the distribution of coronary heart disease factors. The book provides information on trends in growth, height weight for height and subcutaneous arm tissue, and in respiratory health, asthma attacks and related symptoms, in children aged 5 to 11 years, from 1972 to 1994. It provides information on risk factors for impaired growth, obesity and respiratory disease, and on the distribution of risk factors for coronary heart disease in children. The contribution of the National Health and Growth Study extended to topics such as the effects of changes in welfare policy, under-diagnosis and under-treatment of asthma, nocturnal enuresis, disturbed sleep, the impact of passive smoking on the health of children, and the relation of lung function to the child's intra-uterine environment and to passive smoking. The methodological issues in relation to the conduct of the study and analysis of the data are discussed in non-technical language. Each contribution of the study is discussed in relation to current literature, which is fully referenced throughout.

"In Caring for Our Own, Sandra Levitsky has written a moving and perceptive account of the dilemma facing those who provide care for frail family members. Based on in-depth interviews and participant observation with family caregivers and the social workers that attempt to ameliorate their burden, this book uncovers the complex ideological and political factors that have made long term care the neglected stepchild of the welfare state in the United States."-Jill Quadagno, Mildred and Claude Pepper Eminent Scholar in Social Gerontology, Florida State University Aging populations and dramatic changes in health care provision, household structure, and women's labor force participation over the last half century have created what many observers have dubbed a "crisis in care": demand for care of the old and infirm is rapidly growing, while the supply of private care within the family is substantially contracting. And yet, despite the well-documented adverse effects of contemporary care dilemmas on the economic security of families, the physical and mental health of family care providers, the bottom line of businesses, and the financial health of existing social welfare programs, American families have demonstrated little inclination for translating their private care problems into political demands for social policy reform. Caring for Our Own inverts an enduring question of social welfare politics. Rather than asking why the American state hasn't responded to unmet social welfare needs by expanding social entitlements, this book asks: Why don't American families view unmet social welfare needs as the basis for demands for new state entitlements? How do traditional beliefs in family responsibility for social welfare persist even in the face of well-documented unmet need? The answer, this book argues, lies in a better understanding of how individuals imagine solutions to the social welfare problems they confront and what prevents new understandings of social welfare provision from developing into political demand for alternative social arrangements. Caring for Our Own considers the powerful ways in which existing social policies shape the political imagination, reinforcing longstanding values about family responsibility, subverting grievances grounded in notions of social responsibility, and in some rare cases, constructing new models of social provision that would transcend existing ideological divisions in American social politics.