A combination of population growth, public health failures, environmental degradation and rapid global transportation has resulted in a world that is at increasing risk to vectorborne and other infectious diseases. A large percentage of emerging diseases are vectorborne and over one-third of the agents on the list of greatest concern from bioterrorism are vectorborne. Many of these diseases are viral that have no effective drug or vaccine treatments. Drug and insecticide resistance is now common and has greatly compromised our ability to provide effective and affordable control. Parasitic diseases, including malaria, leishmmaniasis and African trypanosomiasis are likewise increasing in many parts of the world. Control programs for onchocerciasis and to some extent filariasis are reducing the impact of these diseases, largely due to the availability of filaricides such as ivermectin. Chagas disease has also declined significantly through home improvements and indoor insecticide application against the domicilary kissing bug vectors.
Despite these gains, this tend has not been sustainable. Instead, infectious disease is now responsible for greater than 25% of all deaths and nearly 50% of premature deaths among those under 45 years of age, and 63% for children less than 4 years of age. A significant proportion of these deaths is attributed to vectorborne diseases, particularly from malaria ( 11%). Indeed, more that 1 million people are killed annually by malaria, about 3000 per day. It is estimated that 700,000 children under the age of 5 die of malaria and at least 300 million are ill due to malaria each year. In response, the American Institute of Medicine (2003) has called for a renewed effort to rebuild public health infrastructures needed to conduct disease surveillance and vector control programs and to increase research to provide improved pesticides and their use, new repellents, new biopestcides and biocontrol agents to augment pesticidal control, as well as novel strategies to interrupt pathogen transmission.
With these goals in mind, we convened the first vector control symposium as part of the scientific program of the 3rd Pan-Pacific Conference of Pesticide Science in 2003. Five years after (2008), we re-convened this expanded topic at the 4th Pan-Pacific Conference on Pesticide Science and the scientific presentations made over two days comprise this current volume, Advances in Human Vector Control. The book covers two major areas: 1) Current Status and Control Practices, covering malaria, dengue, Chagas, human lice, cockroach and house dust mite issues; and 2) Novel Approaches and Resistance Management of these diseases. Chapters are provided by internationally-recognized experts who are actively involved in vector control and management, providing an up to date summary of this critically important area of public health. The effective use of novel control strategies is stressed and the status of recently acquired genomic approaches is critically reviewed.

This volume examines recent developments in the use of intelligent materials and systems for drug delivery. Controlled release technology is moving from being a simple carrier of active agents to becoming a powerful and flexible method that permits subtle modulation of the delivery profile based on the needs of the biological host. The chapters collected here cover recent advances in materials with responsive properties, novel concepts in controlled release technology, new applications, and microanalytical techniques for rapid and accurate measurements of small samples.

This book brings together current thought on several aspects of the use of pesticides in and around homes, schools and workplaces. The book addresses several parts of the process, from the discovery and development of new active ingredients, their formulation, use, longevity, environmental fate and human exposure.

Urban planning is deeply implicated in both the planetary crisis of climate change and the personal crises of unhealthy lifestyles. Worldwide health issues such as obesity, mental illness, growing health inequalities and climate vulnerability cannot be solved solely by medicines but also by tackling the social, economic and environmental determinants. In a time when unhealthy and unsustainable conditions are being built into the physical fabric of cities, a new awareness and strategy is urgently needed to putting health and well-being at the heart of planning. The Routledge Handbook of Planning for Health and Well-being authoritatively and comprehensively integrates health into planning, strengthening the hands of those who argue and plan for healthy environments. With contributions from international leaders in the field, the Handbook of Planning for Health and Well-being provides context, philosophy, research, processes, and tools of experienced practitioners through case studies from four continents.

This book focuses on broadly defined areas of chemical information science- with special emphasis on chemical informatics- and computer-aided molecular design. The computational and cheminformatics methods discussed, and their application to drug discovery, are essential for sustaining a viable drug development pipeline. It is increasingly challenging to identify new chemical entities and the amount of money and time invested in research to develop a new drug has greatly increased over the past 50 years. The average time to take a drug from clinical testing to approval is currently 7.2 years. Therefore, the need to develop predictive computational techniques to drive research more efficiently to identify compounds and molecules, which have the greatest likelihood of being developed into successful drugs for a target, is of great significance. New methods such as high throughput screening (HTS) and techniques for the computational analysis of hits have contributed to improvements in drug discovery efficiency. The SARMs developed by Jurgen and colleagues have enabled display of SAR data in a more transparent scaffold/functional SAR table. There are many tools and databases available for use in applied drug discovery techniques based on polypharmacology. The cheminformatics approaches and methodologies presented in this volume and at the Skolnik Award Symposium will pave the way for improved efficiency in drug discovery. The lectures and the chapters also reflect the various aspects of scientific enquiry and research interests of the 2015 Herman Skolnik award recipient.

The Oregon State Insane Asylum was opened in Salem on October 23, 1883, and is one of the oldest continuously operated mental hospitals on the West Coast. In 1913, the name was changed to the Oregon State Hospital (OSH). The history of OSH parallels the development and growth in psychiatric knowledge throughout the United States. Oregon was active in the field of electroshock treatments, lobotomies, and eugenics. At one point, in 1959, there were more than 3,600 patients living on the campus. The Oscar-winning movie One Flew Over the Cuckoo's Nest was filmed inside the hospital in 1972. In 2008, the entire campus was added to the National Register of Historic Places, and the state began a $360-million restoration project to bring the hospital to modern standards. The story of OSH is one of intrigue, scandal, recovery, and hope.

THE MILLION-COPY BESTSELLER Do you ever feel worried, miserable or unfulfilled - yet put on a happy face and pretend everything's fine? You are not alone. Stress, anxiety, depression and low self-esteem are all around. Research suggests that many of us get caught in a psychological trap, a vicious circle in which the more we strive for happiness, the more it eludes us. Fortunately, there is a way to escape from the 'Happiness Trap' in this updated and expanded second edition which unlocks the secrets to a truly fulfilling life. This empowering book presents the insights and techniques of Acceptance and Commitment Therapy (ACT), covering more topics and providing more practical tools than ever before. Learn how to clarify your values, develop self-compassion and find true satisfaction with this bigger and better guide to: * Reducing stress and worry * Handling painful thoughts and feelings more effectively * Breaking self-defeating habits * Overcoming insecurity and self-doubt * Building better relationships * Improving performance and finding fulfilment at work The Happiness Trap is for everyone. Whether you're lacking confidence, facing illness, coping with loss, working in a high-stress job, or suffering from anxiety or depression, this book will show you how to build authentic happiness, from the inside out.

First published in 1935, this book provides a valuable contribution to the history of Public Health and Preventive Medicine. Written as a recollection of the experiences and knowledge of Sir Arthur Newsholme, the book covers a period in which phenomenal progress was made.

Occupational Health: Management and practice for health professionals explains the relationship between health and work as a two-way process.

This book is aimed at those completing the occupational health component of a basic healthcare programme or pursuing a career in occupational health practice. An update is needed as the research and legislation is dated and there are new developments in the field of environmental health.

The previous edition was published in 2016.

Originally published in 1995, the first edition of Managing Your Mind established a unique place in the self-help book market. A blend of tried-and-true psychological counseling and no-nonsense management advice grounded in the principles of CBTand other psychological treatments, the book straddled two types of self-help literature, arguing that in one's personal and professional life, the way to success is the same. By adopting the practical strategies that mental health experts Butler and Hope have developed over years of clinical research and practice, one can develop the "mental fitness" necessary to resolve one's personal and interpersonal challenges at home and work and to live a productive, satisfying life.
The first edition addressed how to develop key skills to mental fitness (e.g., managing one's time better, facing and solving problems better, keeping things in perspective, learning to relax, etc.), how to improve one's relationships, how to beat anxiety and depression, and how to establish a good mind-body balance. For this new edition, Butler and Hope have updated all preexisting material and have added five new chapters-on sexuality and intimate relationships; anger in relationships; recent traumatic events and their aftermath; loss and bereavement; and dealing with the past.

Health Promotion in Midwifery explores the principles of health promotion within the practical context of midwifery. It clearly outlines and discusses the midwife's role in health promotion, making it essential reading for all student and practising midwives, as well as clinical practitioners. Emphasizing the link between theory and practice, the second edition incorporates chapters on domestic violence, sexual health, breastfeeding, and mental health promotion. Text boxes make the text accessible and user-friendly and case studies and summaries put the material in practical context. Additional readings encourage readers to further research and reflection on their own practice. Throughout the book, the importance of the role of the midwife in health promotion is emphasized. This second edition brings together contributions from a variety of experienced practitioners.

‘How can there be only one dedicated hospital in the country for our children?’

When Madiba asked this question, he sowed the seeds of a challenge that would grow into a legacy.

A seed may be small but its size is disproportionate to what it can become over time. The Nelson Mandela Children’s Hospital was a project that seemed impossible when it was just an idea that started with ten people seated around a dinner table. As they discussed the state of healthcare in the country and shared their experiences, they realised that it was the children of Southern Africa who were the most disadvantaged by the lack of dedicated paediatric facilities. At the end of the evening a statement by the late Dr Nthato Motlana took hold and became the catalyst for a remarkable journey: ‘I will speak to Nelson,’ he said.

With South Africa’s first democratically elected president Nelson Mandela’s backing, the board of the Children’s Fund was inspired to take up the challenge to address this vital need. After years of global research and advice from experts in numerous different fields a Trust was formed to oversee the project and, critically, to set about raising the one billion rand it would take to build, equip and staff a state-of-the-art children’s hospital.

The stories behind the planning for, fundraising and building of the Nelson Mandela Children’s Hospital are inspiring, personal, and sometimes heart-breaking. It was a long and arduous journey, beset with difficulties, but the dedicated team’s commitment and courage prevailed to create a living legacy that will truly impact the lives of children for generations to come.

Today, the Nelson Mandela Children’s Hospital in Johannesburg is a proud testimony to a uniquely African story which honours the memory of a great statesman and celebrates the children for whom he cared so deeply.

Essential medical codes of the Diagnostic and Statistical Manual of Mental Health Disorders 5-TR at your fingertips in 6 laminated pages. Succinctly written by author Rona Bernstein, PsyD to cover the most used codes and core of the DSM. The previous version of this quick reference guide (before this TR version) was a best seller on Amazon and was highly praised. Customers say it is invaluable for those in medical coding and billing for mental health. The value at this price is unbeatable so add this tool to your library to make finding common codes easy until you are seasoned and have them memorized. 6-page laminated guide includes medical codes for common disorders including: Neurodevelopmental Disorders Schizophrenia Spectrum & Other Psychotic Disorders Bipolar & Related Disorders Depressive Disorders Anxiety Disorders Obsessive-Compulsive & Related Disorders Trauma- & Stressor-Related Disorders Dissociative Disorders Somatic Symptom & Related Disorders Sleep-Wake Disorders Feeding & Eating Disorders Sexual Dysfunctions Elimination Disorders Disruptive, Impulse-Control & Conduct Disorders Gender Dysphoria Substance-Related & Addictive Disorders Neurocognitive Disorders Personality Disorders Paraphilic Disorders Other Mental Disorders & Additional Codes Medication-Induced Movement Disorders & Other Adverse Effects of Medication Other Conditions That May Be a Focus of Clinical Attention

Big ideas that just might save the world. the Guardian A serious book on an important subject. Without imagination, where are we? Sir Quentin Blake What if we took play seriously? What if we considered imagination vital to our health? What if we followed nature’s lead? What if school nurtured young imaginations? What if things turned out okay? Rob Hopkins asks the most important question that society has somehow forgotten – What If? Hopkins explores what we must do to revive and replenish our collective imagination. If we can rekindle that precious creative spark, whole societies and cultures can change – rapidly, dramatically and unexpectedly – for the better. There really is no end to what we might accomplish. From What Is to What If is the most inspiring, courageous and necessary book you will read this year; a call to action to reclaim and unleash the power of our imaginations and to solve the problems of our time. Meet the individuals and communities around the world who are doing it now – and creating brighter futures for us all.  At last, we have a design for our dreams. I believe we have a debt of honour to take action. Please read this book and defy the herd. Are we golden or are we debris? Mark Stewart, musician, The Pop Group and Mark Stewart & The Maffia