Written by two urologists and a genitourinary physician, this impeccably researched text provides the reader with a comprehensive overview of sexual health, exploring a range of topics such as: sexually transmitted infections; contraception; urological conditions; genital dermatoses; sexual dysfunction; novel therapeutic options. With a clear, symptom-based format, this is an ideal quick reference guide for the consulting room and the ward.

The potential impact of work being conducted in genomics, proteomics, and metabolomics upon clinical practice for gynecologists is immense but not yet completely appreciated. This groundbreaking text from international experts examines the newest topics on the perinatal agenda and gives clinicians a real look into the future via the newest methodologies.

The life and work of Ignaz Semmelweis is among the most engaging and moving stories in the history of science. "Childbed Fever" makes the Semmelweis story available to a general audience, while placing his life, and his discovery, in the context of his times. In 1846 Vienna, as what would now be called a head resident of obstetrics, Semmelweis confronted the terrible reality of childbed fever, which killed prodigious numbers of women throughout Europe and America. In May 1847 Semmelweis was struck by the realization that, in his clinic, these women had probably been infected by the decaying remains of human tissue. He believed that infection occurred because medical personnel did not wash their hands thoroughly after conducting autopsies in the morgue. He immediately began requiring everyone working in his clinic to wash their hands in a chlorine solution. The mortality rate fell to about one percent. While everyone at the time rejected his account of the cause of the disease because his theory was fundamentally inconsistent with existing medical beliefs about how diseases were transmitted, in time Semmelweis was proven to be correct. His work led to the adoption of a new way of thinking about disease, thus helping to create an entirely new theory--the etiological standpoint--that still dominates medicine today.

Evidence-based clinical guidelines are designed to provide systematically developed recommendations to assist clinicians and their patients in making decisions about appropriate treatment for specific conditions. While these may often be widely available, nowhere are they collated into a single, practical text. This book will fill this need for those working in maternal-fetal medicine, comprehensively covering the conditions, diagnostic and therapeutic challenges faced by those working in fetal care. Presented in highly illustrated, algorithm format with fetograms and autopsy correlations included, this book will aid in the diagnosis, investigation, counselling and therapeutic options for the management of fetal abnormalities and disorders.

This beautifully illustrated book provides a practical step-by-step guide to all the laparoscopic and hysteroscopic procedures performed by gynecologists. Each procedure is described in detail and fully illustrated with color photographs. The potential complications are described, and the circumstances in which a procedure is contraindicated are examined. The Third Edition of the "Manual of Laparoscopic and Hysteroscopic Techniques" has been expanded and extensively updated with new chapters including: transvaginal hydrolaparoscopy, laparoscopy radical trachelectomy, laparoscopic abdominal cerclage, and hysteroscopy sterilization. "Manual of Laparoscopic and Hysteroscopic Techniques" is an invaluable resource for busy practicing gynecologists who want to learn step-by-step techniques of a surgical procedure.

The endocrine and neuroendocrine system in pregnancy involves highly complex maternal, fetal and placental mechanisms, which are critical for the maintenance of pregnancy, the timing of parturition, for fetal growth and protection from adverse fetal programming. This timely book summarizes the different endocrine aspects related to pregnant women, describing how hormones regulate physiological homeostasis and influence the pathogenesis of disease. The first section of the book covers the role of specific hormones in detail, including oxytocin, hCG and estrogen. The second section discusses gestational disorders such as diabetes, hypertensive disorders and preeclampsia and how the involvement of hormones has clinical implications for management. Best practice for management of endocrine disorders, which can negatively impact pregnancy, such as thyroid disease and obesity, is also reviewed. This book is essential for clinicians and scientists looking to gain knowledge of the role of hormones in pregnancy and how they can best support patients.

This is a new book on the integrated management of vulvovaginal disease. The authors come from a variety of backgrounds - gynaecology, dermatology, pathology and psychology - and describe a multidisciplinary approach to these conditions. The book has the most complete classification of vulvovaginal disease published, based on the etiology of 275 conditions; coverage includes benign, malignant, and functional (including psychosexual) diseases. Each disease has a descriptive summary, pathological features, and treatment guidelines. The book is illustrated in full color throughout.

Now in its second edition, this bestselling title has been extensively revised and expanded to include new topics on: obesity and breast cancer induction of anti-hormone and anti-growth factor resistance in breast cancer clinical implications of testosterone and breast cancer insulin-like growth factors discussions on the biological, genetic, and molecular pathways linked to the development and progression of breast cancer analyses on the latest therapeutic strategies, prognostic and predictive factors, and prevention strategies Examining new developments, Breast Cancer: Prognosis, Treatment, and Prevention, Second Edition also covers: the mechanism involved in carcinogenesis the relationship among a fetus, pregnancy, and breast cancer recent developments in endocrine treatment the relationship among hormone replacement therapy, cytotoxic therapy, and other non-hormonal approaches for the treatment of metastases management of locally advanced breast cancer, and the importance of BRCA-1 and BRCA-2 in hereditary breast cancer With new topics and updated chapters, this new edition keeps both oncologists and radiologists abreast of the current trends and advancements in the prognosis, treatment, and prevention of breast cancer.

The fourth volume in the Atlas of Human Central Nervous System Development series, The Human Brain During the Late First Trimester provides new information about features of the perinatal brain. It deals with brain development during the late first trimester (GW11-GW7.5). The major theme of this volume is the identification of stretches and patches (mosaics) of the NEP matrix along the hypertrophied telencephalic, diencephalic, mesencephalic, and rhombencephalic superventricles. Many putative migratory paths of young nerons on their way to their settling sites are also identified. In the younger specimens, the brain sections are presented as they are embedded in the skull and developing facial structures. The older specimens show the onset of development of some of the large fiber tracts. Like the rest of the series, it contains photographs of the entire brain arranged in companion plates that include two parts: a large, high resolution black and white photograph and a "ghost image" of the photograph with unabbreviated labels. It is a user-friendly survey of the complex structural processes that occur during human CNS development. This volume can be purchased as part of the complete five volume set.

Understanding immunology is increasingly important in obstetrics and gynecology. Written primarily to meet the needs of practicing obstetricians and gynecologists, this book explores the role of immunological processes in reproduction. It presents immunologic concepts and illustrates important points with examples familiar to the clinician. The book is organized into four sections that explore the fundamentals of the immune system, the immunological paradox of pregnancy, clinical applications of immunology in obstetric and gynecologic practice, and immunopathology in obstetric and gynecologic practice. Written mainly for practicing obstetricians and gynecologists, the research results cited in the book are based on human experimentation. Fully illustrated with clear schematic drawings that highlight important concepts and processes, The Immunology of Human Reproduction gives readers an essential overview of immunology as it relates to human reproduction.

Keeping up with the rapid growth in this field, A Practical Manual of Hysteroscopy and Endometrial Ablation: A Clinical Cookbook covers current and emerging endometrial ablation procedures. It provides practical, step-by-step illustrated descriptions of basic and advanced techniques and new methods. The editors, Resad Pasic and Ronald L. Levine, have brought together a group of experts renowned not only for their knowledge but also their ability to teach. The subtitle, A Clinical Cookbook, was purposely chosen to emphasize that you can literally follow the individual "recipes" of procedures to assure their safe and effective use. Containing the most up-to-date and thorough material available, the book addresses the present hysteroscopic therapies and provides in depth discussion of the current knowledge of hysteroscopy and ablation techniques. Each chapter has the main points highlighted in boxes separated from the text for easy review. The digital drawings were made by use of computer graphics by an outstanding graphic designer, Branko Modrakovic. The illustrations, whether line drawings or actual color photographs, clearly deliver the message. You can quickly grasp what to do, and just as importantly, what not to do.

Gestational Diabetes Mellitus is becoming an increasingly prevalent disease as obesity and other chronic diseases are on the rise. It requires careful and informed clinical management as the care received during pregnancy affects not only perinatal health but the risk of developing type 2 diabetes even decades into the future, in both the mother and the child.From epidemiology and pathophysiology to diagnosis and management, covering recent breakthroughs in research and up-to-date developments in clinical practice, Gestational Diabetes During and After Pregnancy offers the reader a comprehensive and current look at Gestational Diabetes. Anyone involved in the research, public health or clinical aspects of Gestational Diabetes will find this volume a valuable aid in consolidating all recent developments regarding this disease.

There are many possible causes of pelvic pain in a non-pregnant female patient, and it has been estimated to be responsible for nearly 40% of all visits by female patients to a family doctor and 10% of all referrals to specialist gynecologists. However, the topic of how to investigate and diagnose has been surprisingly neglected in print. This important and much-needed text from internationally respected experts shows how important ultrasound can be as a tool for physicians caring for women's health.

The discovery of ER by Dr. Elwood Jensen exactly 60 years ago has not only led to the birth of a whole new vital nuclear receptor research field but also made a rapid, direct and lasting impact on the treatment and prevention of breast cancer. Since that landmark discovery, tremendous progress has been made in our understanding of the molecular functions of ER and development of targeted therapies against ER pathways for breast cancer treatment. However, there is currently no book available addressing these discoveries and recent advancement in a historical and systematic fashion. This book is intended to provide comprehensive, most up-to-date information on the history and recent advancement of ER and breast cancer by world renowned leaders in the field. These chapters include the history of the discovery of ER; physiological and pathological roles of ER; recent discovery of ER cistrome, transcriptome and its regulation of noncoding RNAs such as microRNAs and enhancer RNAs in breast cancer; development and clinical practices of the first targeted therapy Tamoxifen and other antiestrogens for breast cancer treatment; structural basis of ER and antiestrogen actions; molecular insights into endocrine resistance; the role of ER mutants, ER-beta and environmental estrogens in breast cancer; and emerging state-of-the-art therapeutic approaches currently in development to overcome treatment resistance and future perspectives. The book will provide undergraduate and graduate students, basic scientists and clinical cancer researchers, residents, fellows, as well as clinicians, oncology educators and the general public a thorough and authoritative review of these exciting topics.

This easy-to-understand pocketbook in the highly respected Clark’s stable of imaging texts is an invaluable tool and training aid, providing essential information for mammographic positioning, technique and interpretation for mammography practitioners at all levels. Adopting a systematic and structured approach facilitating rapid reference in the clinical setting, the book covers general principles and all routine mammographic projections, including additional and adapted projections covered in a separate section, and is highly illustrated with clear explanatory line diagrams and imaging photographs. Clark’s Essential Guide to Mammography is ideal as an educational tool for trainee mammographers, trainee assistant and associate apprenticeship mammographers, mammography training teams and universities delivering mammography education and a convenient clinical guide for practising mammographers, including assistant and associate apprenticeship mammographers.

There are many possible causes of pelvic pain in a non-pregnant female patient, and it has been estimated to be responsible for nearly 40% of all visits by female patients to a family doctor and 10% of all referrals to specialist gynecologists. However, the topic of how to investigate and diagnose has been surprisingly neglected in print. This important and much-needed text from internationally respected experts shows how important ultrasound can be as a tool for physicians caring for women's health.

Get Through MRCOG Part 2: MCQs covers the breadth and depth of the MRCOG Part 2 examination syllabus and is an essential revision tool for candidates preparing for this examination. The comprehensive and wide collection of practice questions is designed to help the candidate test and assess their knowledge of the subject, aiding them in thorough preparation for the exam. The text contains 750 multiple choice stems, each with around four associated questions, providing the reader with a total of 3000 individual questions with which to test themselves. The material is divided up by subject area, allowing candidates to test their knowledge on a particular topic. The 13 'modules' are followed by two mock papers, each containing a selection of questions on different subject areas, which the reader can attempt under timed conditions. Answers are provided, with useful explanatory information for all questions to help the reader understand why their answer is right or wrong. The author, Paul Ayuk, was clinical lecturer in obstetrics and gynaecology at Oxford University for 6 years and has run an on-line MRCOG course for over 5 years, assisting over 8000 candidates worldwide.

For around half of the couples who have trouble conceiving the cause of infertility is sperm-related. Intracytoplasmic sperm injection (ICSI) is the most common and successful treatment for male infertility. Here, the pioneers for the technique, along with authorities in the field, describe the underlying science of ICSI and other micromanipulation techniques. Practical advice for performing the techniques is covered in depth, including sperm selection, laser-assisted ICSI, and the use of piezo in ICSI. Examining the safety of ICSI in animal models as well as the impact of ICSI on the health and well-being of the children conceived through the procedure is discussed. This manual is an essential resource for clinical embryologists and laboratory personnel wishing to refine or develop techniques and improve outcomes.

During the early 1990s, global health experts developed a new model of emergency obstetric care: post-abortion care or PAC. In developing countries with restrictive abortion laws and where NGOs relied on US family planning aid, PAC offered an apolitical approach to addressing the consequences of unsafe abortion. In Dying to Count, Siri Suh traces how national and global population politics collide in Senegal as health workers, health officials, and NGO workers strive to demonstrate PAC’s effectiveness in the absence of rigorous statistical evidence that the intervention reduces maternal mortality. Suh argues that pragmatically assembled PAC data convey commitments to maternal mortality reduction goals while obscuring the frequency of unsafe abortion and the inadequate care women with complications are likely to receive if they manage to reach a hospital. At a moment when African women face the highest risk worldwide of death from complications related to pregnancy, birth, or abortion, Suh’s ethnography of PAC in Senegal makes a critical contribution to studies of global health, population and development, African studies, and reproductive justice.  

The Diploma of the Royal College of Obstetricians and Gynaceologists (DRCOG) examination consists of 60 multiple choice questions (MCQs) and 22 six minute structured clinical examination stations (OSCEs), of which two are rest stations. This one day examination is designed for General Practice trainees, ideally with six months' experience in obstetrics and gynaecology at the senior house officer grade.This book presents three complete DRCOG MCQ and OSCE circuits and encompasses all the possible MCQ and OSCE topics that can and have been asked in the DRCOG examination. They are presented in an identical way to the exam itself.The author, Mrs Una Coales MD, FRCSEd, DRCOG, trained in medicine in the USA and moved to practise in the UK. She has taken and passed the DRCOG exam herself and has also published popular exam texts for PLAB Parts 1 and 2.

This title is designed to help the candidate in preparation for the short essay paper components of the written MRCOG Part II examination. By providing a section of model answers with bullet points indicating specific points where marks are allocated, this text provides the candidate with a firm grounding in examination principles and technique for the short essay question papers. A section of practice papers is provided, 10 in obstetrics and 10 in gynaecology with marking schemes by which the reader can test their knowledge under examination conditions. Also valuable as a revision aid, this book highlights the core information that is central to all the MRCOG Part II examination components.

This extensively illustrated book provides an accessible and up-to-date introduction to obstetric anaesthesia and analgesia. With only three principal authors, there is a consistency of style within a comprehensive textbook that presents the basic science, pharmacology and clinical practice relevant to obstetric anaesthesia. Chapters cover topics such as analgesia during labour, anaesthesia and postoperative analgesia for caesarean delivery, major obstetric and anaesthetic complications, evaluation of the foetus and resuscitation of the neonate, and common clinical scenarios such as management of pre-eclampsia, obesity, multiple gestation and co-existing disease.

This collection brings together the leading research in maternity care from the United States, Canada and Europe to discuss systems of care for pregnancy and childbirth. The essays focus on the practical side of "good" social science and "feminist-friendly" research. The text not only looks at maternity, but also the act of childbirth, with the goal of providing not just comparative perspectives of care, but also to integrate the differences in care within each essay for a truly international understanding of maternity care.

This book is a collection of original essays on the meaning of providing care. These essays address not only the work of caring for the elderly, but also the work of caring for children, the infirm and those with disabilities.
The essays approach the topic from an ethical standpoint and also from a more practical, feminist and sociological point of view. The main goal of this book is to re-conceive the notion of care work, beginning with steps as simple as replacing the phrase 'caregiver' with the phrase 'care worker'.