Major advances in genetics, immunology, and endocrinology have necessitated a new edition of this best-selling text. However, despite the advances, recurrent pregnancy loss presents a frustrating clinical problem. There is still disagreement about the number of pregnancy losses which warrant investigation and treatment and about which investigations should be performed. This third edition provides an authoritative and comprehensive update on advances in the understanding and management of this troubling phenomenon, covering both basic scientific topics such as genetics and cytokines, and profiles major advances in immunology, endocrinology, and thrombotic mechanism. Clinical research is discussed, as is assessment of results when applying an evidence-based approach or a more personalised approach, which is now becoming possible due to advances in the diagnosis of cause. There are lively debates on the role of progestogens and immunotherapy, which remain controversial. Designed for specialists working in reproductive medicine clinics and those involved with maternal-fetal care, the book is also ideal for generalists and gynecologists seeking a comprehensive view of developments in the field.

This book is a hands-on guide for facilitating treatment of anxiety and depression during pregnancy and the postpartum period. Readers will learn about why anxiety and related difficulties can increase during pregnancy and the postpartum period, the critical roles that thoughts and behaviors play in maintaining symptoms, and how to apply practical cognitive and behavioral strategies to reduce distress and increase coping skills. Chapters are integrated with the latest research, and clinicians and individuals alike are presented with customizable cognitive behavioral therapy-based handouts, exercises, and worksheets proven to meet the unique needs of the perinatal population.

In this issue of Surgical Pathology Clinics, guest editor Dr. Carlos Parra-Herran brings his considerable expertise to the topic of Gynecologic and Obstetric Pathology. Top experts cover emerging topics in gynecologic pathology that are relevant to clinical practice, including information on classification, terminology, diagnostic criteria, and ancillary testing. This issues also includes a review of the pathologic findings in specimens from patients undergoing gender-affirming surgery. Contains 14 practice-oriented topics including placental pathology: integrating consensus recommendations into practice; gestational trophoblastic neoplasia: contemporary diagnostic approach; homologous recombination deficiency and BRCA testing in pelvic high-grade serous carcinoma; ovarian sex cord stromal tumors and their mimickers; and more. Provides in-depth clinical reviews on gynecologic and obstetric pathology, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

Why is it that women suffer far more than men from insomnia? What is the connection between the hormonal changes that a woman undergoes during her lifetime, and difficulty in falling asleep? What is the effect of cell phones on sleep? Should women engage in sports before going to sleep? What do women primarily dream about? In which country do people sleep the most? How do depression and anxiety affect sleep? And why is it inadvisable to resort to a "little pill" to provide unworried sleep? This clear and readable book, illustrated with short quotations of poetry and prose about sleep and dreams, provides a glimpse into the wonderful mechanism of sleep, explains how correct treatment of sleep disturbances results from understanding their causes, and shows the right path to a pleasant and satisfying night's sleep; it will be of great interest for all women and clinicians dealing with female patients. In particular, because of the connection between sleep and hormones, problems with sleep have repercussions for women's reproductive life cycle. This pioneering text will therefore be of particular interest to gynecologists working in Reproductive Medicine.

This book presents the latest and most essential techniques in Aesthetic Mastoplasty, an important field in plastic surgery that allows us to reshape breasts in harmony with the body's contours and with the patients' sense of beauty. Moreover, there have been major advances in this area in recent years, leading to improved and more tailored surgical outcomes. Breast surgeons should familiar with the most recent techniques in breast surgery, in order to provide a high standard of quality and patient-tailored surgical service. With these goals in mind, the book discusses the most important issues in the field, divided into four different sections: General Information for Breast Surgery, Surgical Principles of Breast Surgery, Breast Augmentation, and Liposuction and Lipoinjection. Written by a respected breast surgeon to honor the remarkable contributions of Prof. Ivo Pitanguy and featuring contributions from 39 Brazilian plastic surgeons, Breast Surgery - Aesthetic Approaches highlights the essentials and the latest advances developed by Brazilian plastic surgeons over the past 37 years. As such, it offers an invaluable practical surgical manual for all readers interested or working in breast surgery, including plastic and breast surgeons and plastic surgery residents.

Fibroids are benign growths of the uterus. They are the most common tumours found in women (20-30% of women), usually in later reproductive years. This book covers evidence-based indications for treatment of uterine fibroids in gynecology, the management of fibroids in pregnancy, surgical treatments and outcomes, rare fibroid syndromes, and more.

Offering a one-stop guide to recognition and therapeutic decision making, Diagnosis and Treatment of Rare Gynecologic Cancers fills a gap in the medical literature on uncommon ovarian, uterine, cervical, and vulvovaginal cancers and trophoblastic diseases. This authoritative text, edited by Drs. Michael Frumovitz, Mario Leitao, and Preetha Ramalingam, has been authored by internationally recognized experts from top institutions such as MD Anderson Cancer Center and Memorial Sloan Kettering Cancer Center. Each chapter covers different cancer subtypes and has been reviewed by an oncologist and a pathologist. Provides up-to-date clinical guidance on assessment and therapeutic options for patients with rare gynecologic malignancies. Presents information in a templated, easy-to-read format. Each chapter includes an introductory clinical case followed by epidemiology of disease, pathologic assessment, basic science/molecular/translational research, work-up of newly diagnosed disease, staging, treatment of newly diagnosed disease, treatment of recurrent disease, potential therapeutic targets, and a case resolution. Includes diagnostic and treatment algorithms for each form of cancer. Contains numerous anatomical figures, radiographs, photographs, and tables for quick visual reference. Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.

Cut It Out examines the exponential increase in the United States of the most technological form of birth that exists: the cesarean section. While c-section births pose a higher risk of maternal death and medical complications, can have negative future reproductive consequences for the mother, increase the recovery time for mothers after birth, and cost almost twice as much as vaginal deliveries, the 2011 cesarean section rate of 33 percent is one of the highest recorded rates in U.S. history, and an increase of 50 percent over the past decade. Further, once a woman gives birth by c-section, her chances of having a vaginal delivery for future births drops dramatically. This decrease in vaginal births after cesarean sections (VBAC) is even more alarming: one third of hospitals and one half of physicians do not even allow a woman a trial of labor after a c-section, and 90 percent of women will go on to have the c-section surgery again for subsequent pregnancies. Of comparative developed countries, only Brazil and Italy have higher c-section rates; c-sections occur in only 19% of births in France, 17% of births in Japan, and 16% of births in Finland. How did this happen? Theresa Morris challenges most existing explanations of the unprecedented rise in c-section rates, which locate the cause of this trend in physicians practicing defensive medicine, women choosing c-sections for scheduling reasons, or women's poor health and older ages. Morris's explanation of the c-section epidemic is more complicated, taking into account the power and structure of legal, political, medical, and professional organizations; gendered ideas that devalue women; hospital organizational structures and protocols; and professional standards in the medical and insurance communities. She argues that there is a new culture within medicine that avoids risk or unpredictable outcomes and instead embraces planning and conservative choices, all in an effort to have perfect births. Based on 130 in-depth interviews with women who had just given birth, obstetricians, midwives, and labor and delivery nurses, as well as a careful examination of local and national level c-section rates, Cut It Out provides a comprehensive, riveting look at a little-known epidemic that greatly affects the lives, health, and families of each and every woman in America.

A critical analysis of white, working class North Americans' motivations and experiences when traveling to Central Europe for donor egg IVF Each year, more and more Americans travel out of the country seeking low cost medical treatments abroad, including fertility treatments such as in vitro fertilization (IVF). As the lower middle classes of the United States have been priced out of an expensive privatized "baby business," the Czech Republic has emerged as a central hub of fertility tourism, offering a plentitude of blonde-haired, blue-eyed egg donors at a fraction of the price. Fertility Holidays presents a critical analysis of white, working class North Americans' motivations and experiences when traveling to Central Europe for donor egg IVF. Within this diaspora, patients become consumers, urged on by the representation of a white Europe and an empathetic health care system, which seems nonexistent at home. As the volume traces these American fertility journeys halfway around the world, it uncovers layers of contradiction embedded in global reproductive medicine. Speier reveals the extent to which reproductive travel heightens the hope ingrained in reproductive technologies, especially when the procedures are framed as "holidays." The pitch of combining a vacation with their treatment promises couples a stress-free IVF cycle; yet, in truth, they may become tangled in fraught situations as they endure an emotionally wrought cycle of IVF in a strange place. Offering an intimate, first-hand account of North Americans' journeys to the Czech Republic for IVF, Fertility Holidays exposes reproductive travel as a form of consumption which is motivated by complex layers of desire for white babies, a European vacation, better health care, and technological success.

Identifying Perinatal Depression and Anxiety brings together the very latest research and clinical practice on this topic from around the world in one valuable resource. * Examines current screening and management models, particularly those in Australia, England and Wales, Scotland, and the United States * Discusses the evidence, accuracy, and limitations of screening methods in the context of challenges, policy issues, and questions that require further research * Up to date practical guidance of how to screen, assess, diagnose and manage is provided. * Considers the importance of screening processes that involve infants and fathers, additional training for health professionals, pathways to care following screening, and the economics of screening * Offers forward-thinking synthesis and analysis of the current state of the field by leading international experts, with the goal of sketching out areas in need of future research

Now in its 3rd edition, Lecture Notes: Obstetrics and Gynaecology has been extensively revised and updated to provide a concise and practical introduction to obstetrics and gynaecology for medical students and junior doctors. Starting with a section on basic science, the text is divided into six sections that explain female health needs and their management from the early years to old age. The self-assessment section is now a separate chapter, and includes Extended Matching Questions (EMQs), scenarios for practical history taking for the Objective Structured Clinical Examination (OSCE) and Multiple Choice Questions (MCQs). Part 1 looks at female reproductive anatomy and physiology. Part 2 covers the puberty and menstrual problems of young women, sub-fertility, pregnancy prevention, and sexual problems. Part 3 examines the reproductive years including pregnancy and childbirth. Part 4 covers the mature woman including menstrual problems of the older woman and pelvic pain. Part 5 discusses the older woman including the menopause, incontinence and malignancy including breast cancer. Part 6 demonstrates the importance of public health statistics on the provision of services in obstetrics and gynaecology. Now in two-colour throughout, with a new colour plate section, Lecture Notes: Obstetrics and Gynaecology covers the core material needed for O&G courses, written specifically for medical students, nursing students, junior doctors on the Foundation Programme and the first two years of specialist training, midwives, and GPs.

Rare gynecological cancers kill all too commonly Gynecological cancer is a frightening prospect for women. It is terrifying also for physicians who need, but often can t find, guidance on how to investigate and appropriately treat the tumors. Rare cancers provide greater challenges as information can be harder to find and more difficult to verify. Rare Gynecologic Cancers: Diagnosis and Management brings together all you need to know on these life-threatening diseases. Straightforward summaries of pathophysiologic processes lead to the investigations that will improve your diagnostic accuracy. This provides the basis for you to identify effective treatment strategies for your patients. Written by a world-leading team of Editors and Authors and covering cancers of the Ovaries Uterus Vulva Vagina Cervix Rare Gynecologic Cancers: Diagnosis and Management will guide you to the best life-saving treatment for your patients.

This book is a comprehensive and easy-to-read guide to obstetrics and gynecology in developing countries. Although significant progress has been made towards the reduction of maternal mortality and morbidity globally, they are still unacceptably high in developing countries. This can be directly or indirectly tied to poor quality maternal health care and lack of access to cost-effective, comprehensive healthcare. Health practitioners in developing countries also contend with trying to keep abreast of recent developments in obstetrics and gynecology while dealing with lack of time, resources, and access to relevant information. This textbook was thus created by experts in obstetrics and gynecology with extensive experience in African clinical settings and consultants in developed countries to teach proper and accurate diagnosis, treatment and management of gynecologic and obstetric health issues within the context of developing countries. This second edition has been fully updated throughout with an added 25+ chapters that cover topics such as reproductive health, gynecological cancers and research methods. The book is divided into six sections: Women's Reproductive Health; Obstetrics; Medical and Surgical Disorders in Pregnancy; General Gynecology; Gynecological Malignancies; Health Systems Organization, Research Methodology and Biostatistics. These section topics have been carefully covered by expert authors with the use of valid scientific data, policy instruments, and adapted to the cultural and social context of developing countries, with particular in depth coverage of conditions that have greater prevalence and incidence in developing countries. Each chapter also focuses on filling gaps in knowledge with a distinct pedagogical approach, starting with a set of learning objectives and ending with key takeaways for the chapter. This is an ideal guide for residents, medical students, practitioners of obstetrics and gynecology, midwives, general practitioners, and pediatricians, particularly those working in developing companies.

This book examines the role of psychopharmacological treatment in a range of disorders that may be encountered during pregnancy, including major depressive disorders, anxiety disorders, bipolar affective disorder, schizophrenia, eating disorders and substance abuse. The natural history of each condition pre and post-partum is analyzed and the evidence for the efficacy of drug treatments, evaluated. Special attention is paid to the potential dangers of different treatment options for both mother and fetus, covering risks of malformation, pregnancy and obstetric risks, neonatal risks and possible long-term consequences. The risks of not treating a particular condition are also analyzed. On the basis of the available evidence, management guidelines are provided that additionally take into account non-pharmacological options. Closing chapters consider the value of complementary and alternative medicine and ECT and explore future research directions.

This expert guide will help readers learn about the role of hysteroscopy in the management of a range of common and less common gynaecological problems. In particular, the book covers the diagnosis and treatment of endometrial and uterine anatomical abnormalities that are associated with abnormal uterine bleeding and impairment of reproduction. Contemporary hysteroscopic techniques are described allowing the reader to understand how to perform both inpatient and outpatient procedures. Based on the annual RCOG/BSGE Diagnostic and Operative Hysteroscopy training course, this comprehensive guide covers fundamental topics such as equipment, energy modalities and operative set up. The book also explores innovative ambulatory surgery and hysteroscopic interventions in an operating theatre environment. Written by international experts in hysteroscopy and including sections on training in, and monitoring of clinical practice, this guide proves an ideal companion for health care professionals looking to provide best clinical practice and optimal patient experience.

Engage with practical and active solutions to day-to-day issues of reproductive medicine and the use of artificial reproductive techniques (ART), occurring in clinical and laboratory environments. Authored by leading experts in the field, this user-friendly guide is invaluable for any IVF practitioner and embryologist, facing everyday hands-on issues, through to high-pressure laboratory problems, efficiency ratings and ensuring cost-effective delivery of care. With the strict governance of regulatory bodies worldwide, the success of any fertility centre depends on successful problem solving, all day every day. Based on a wealth of experience, identify commonly occurring problems, and fresh perspectives of problem-solving, with 'must-have' protocols, patient information sheets and suggested equipment. This go-to companion tackles operational, organisational, clinical and laboratory issues to financial and clinical governance, with a focus on quick and effective solutions for the busy practitioner.

Consulting Editor, Dr. William Rayburn, is serving as Guest Editor for this special issue of Obstetrics and Gynecology Clinics devoted to Interprofessional Collaboration for Select Women's Health Issues. Articles deal with the spectrum of disciplines in response to failures of interprofessional collaboration that resulted in compromises to patient quality and safety. Systematic reviews have shown that this type of learning has led to positive outcomes in relation to participant's reactions, attitudes, knowledge/skill, behaviors, and practice, as well as patient benefits. Articles in this issue are specifically devoted to the following topics: Reproductive Rights and Women's Mental Health: Essential Information for the Ob/Gyn; Goals for Collaborative Management of Obstetric Hemorrhage; Role of Lipid Management in women's Health Preventative Care; Stroke in Pregnancy: An Update; Treatment of Viral Infections During Pregnancy; Benign Uterine Disease: The Added Role of Imaging; Racial Differences in Pregnancy-Related Morbidity and Mortality; Psychiatric Medication Use in Pregnancy and Breastfeeding; Neuroimaging During Pregnancy and the Postpartum Period; The Midlife Transition, Depression and Its Clinical Management; and Burnout in Obstetricians-Gynecologists: Its Prevalence, Identification, Prevention, and Reversal. Readers will come away with the information needed to improve patient outcomes while aiming toward goals like interprofessional faculty development that result in reducing feelings of isolation, developing a more collaborative approach, and providing opportunities to share knowledge, experiences, and ideas.

This book comprehensively addresses female and male fertility preservation. It discusses in detail all major aspects of fertility preservation in both sexes, explains the basis of fertility preservation, and highlights the currently available techniques; further chapters are dedicated to specific diseases. The book offers an essential reference guide for all physicians, specialists or not, seeking to improve their grasp of female and male fertility preservation.

Overcoming Drug Resistance in Gynecologic Cancers provides up-to-date information related to important gynecologic cancers and focuses on mechanisms of drug resistance, genetics, signaling, immunology, health disparities, nanotechnology, economic considerations and financial impacts. The book covers not only drug resistance but also important means to reverse resistance both in the laboratory and clinic. The book discusses topics such as lifestyle, nutrition and risk of gynecologic cancers, the financial impact of drug resistance, chemosensitizing agents and targeted therapies in cervical, endometrial and ovarian cancer, immunotherapy to overcome drug resistance, and genetic polymorphisms in gynecologic cancers. Additionally, it discusses ethnic and racial health disparity perspectives and future developments in chemosensitizing activities to reverse drug resistance in gynecologic cancers. It is a valuable resource for cancer researchers, oncologists, clinicians and other biomedical field members who are interested in new approaches to improve chemotherapy outcome in patients with gynecologic cancers.

A 35-year-old woman arrives on the labour ward complaining of abdominal pain and vaginal bleeding at 36 weeks 2 days' gestation. The pain started 2 hours earlier while she was in a cafe and is not relieved by lying still or walking around. The bleeding is bright red. You are the medic on duty... 100 Cases in Obstetrics and Gynaecology presents 100 obstetric- or gynaecology-related scenarios commonly seen by medical students and junior doctors in the emergency department, outpatient clinic, or on the ward. A succinct summary of the patient's history, examination, and initial investigations-including photographs where relevant-is followed by questions on the diagnosis and management of each case. The answer includes a detailed discussion on each topic, with further illustration where appropriate, providing an essential revision aid as well as a practical guide for students and junior doctors. Making speedy and appropriate clinical decisions, and choosing the best course of action to take as a result, is one of the most important and challenging parts of training to become a doctor. These true-to-life cases will teach students and junior doctors to recognize important obstetric and gynaecological conditions, and to develop their diagnostic and management skills.

Uterine fibroids are very common in women of reproductive age and are mostly benign. However, they are often a cause of abnormal bleeding and, in severe cases, can cause infertility. This comprehensive guide reviews the clinical management of uterine fibroids, with a particular focus on practical surgical techniques. Engage with topics such as the anatomy of the pelvis, key theatre equipment and surgical treatments including hysteroscopic and laparoscopic techniques. Features also include debates around morcellation, and less invasive treatments such as uterine artery embolisation are also covered. An online video library of surgical procedures reinforces the practical techniques taught in the book and detailed colour images supplement the book's thorough coverage of fibroid management. This makes Modern Management of Uterine Fibroids an essential resource for practicing gynaecologists and IVF specialists, as well as students.

This book aims to provide updated facts and treatments for practicing gynecologists and postgraduate doctors to enhance their understanding of pathogenesis, pathology, symptoms and diagnostic imaging technology of adenomyosis, such as to select appropriate treatments, to improve the symptoms, fertility and the quality of life of women with adenomyosis. This book also particularly introduces the new treatment for adenomyosis using the non-invasive High Intensity Focused Ultrasound ablation treatment. Hopefully, it will provide a better understanding of its operation, effectiveness, and pregnancy outcome, to formulate a more successful treatment strategy for this disease.

This book is a practical guide for medical practitioners as they navigate through breastfeeding problems that occur in day-to-day practice. If mothers have a breastfeeding complication they are often directed to their GP. In complex situations, medical staff will be making decisions around what treatment plan to follow and whether a mother can keep breastfeeding. In recent years there has been growing evidence that medical professionals often advise mothers to stop breastfeeding while undergoing treatment, when in reality this was not a necessary step. In a time when breastfeeding rates are decreasing, it is important that medical professionals give accurate advice and support a mother's choice to breastfeed if the situation allows it. A Guide to Supporting Breastfeeding for the Medical Profession includes contributions from a wide range of medical professionals and each chapter is written with the practitioner in mind. Contributors include GPs, paediatricians, neonatologists, lactation specialists and midwives. Doctors have a vital role to play in supporting and facilitating breastfeeding, and without the appropriate knowledge they can often inadvertently sabotage it. This book will be of interest to GPs and paediatricians as well as nurse prescribers, midwives and health visitors.

Heart disease is currently the leading cause of maternal mortality in developed countries and is expected to increase further due to advanced maternal age and conditions such as type 2 diabetes. Maternal Cardiac Care: A Guide to Managing Pregnant Women with Heart Disease is an up-to-date, multidisciplinary resource for physicians and advanced practice nurses caring for pregnant patients with a variety of preexisting and emerging cardiac issues. Offers comprehensive information on caring for women with heart disease, in an easy-to-follow, quick-access format. Shares knowledge from a multidisciplinary group of experts who are well versed in the team approach needed to treat this high-risk patient population. Includes extensive references for readers who want to delve more deeply into specific subjects. Ideal for obstetricians, internists, cardiologists, critical care specialists, and advanced practice nurses involved in caring for pregnant patients, as well as institutions and departments that need detailed guidance on establishing a maternal cardiac care program. Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.

Although there are far more opportunities for LGBTQ people to become parents than there were before the 1990s, attention to the reproductive challenges LGBTQ families face has not kept pace. Reproductive Losses considers LGBTQ people's experiences with miscarriage, stillbirth, failed adoptions, infertility, and sterility. Drawing on Craven's training as a feminist anthropologist and her experiences as a queer parent who has experienced loss, Reproductive Losses includes detailed stories drawn from over fifty interviews with LGBTQ people (including those who carried pregnancies, non-gestational and adoptive parents, and families from a broad range of racial/ethnic, socio-economic, and religious backgrounds) to consider how they experience loss, grief, and mourning. The book includes productive suggestions and personal narratives of resiliency, commemorative strategies, and communal support, while also acknowledging the adversity many LGBTQ people face as they attempt to form families and the heteronormativity of support resources for those who have experienced reproductive loss. This is essential reading for scholars and professionals interested in LGBTQ health and family, and for individuals in LGBTQ communities who have experienced loss and those who support them. See additional material on the companion website: www.lgbtqreproductiveloss.org/