Targeted Nanomedicine for Breast Cancer Therapy provides a compilation of treatment approaches for breast cancer, including conventional receptor targeting methods and novel strategies like stimuli responsive methods and tumor micro-environment responsive strategies. This book compiles the most important information on the state-of-the-art therapeutics, including breast cancer biomarkers and design principles of bio-responsive nanosystems. Presented in two parts, sections cover basic and receptor mediated targeting approaches and examine tumor microenvironment mediated approaches. This is a useful book for pharmaceutical scientists and basic and clinical scientists working in the research area of breast cancer and drug discovery both from academics and industry. Worldwide, breast cancer is the most common cancer in women, however, breast cancer therapy is always challenging. This book aims to help researchers remain updated on the most targeted nanomedicine research available.

Vulval diseases are managed by dermatologists and by ObGyns and while expert referral centres do exist, the majority of patients are treated by non-specialists. These conditions are relatively common (approximately 15% of a gynaecologist's caseload) and can be difficult to diagnose. Gynecologic Dermatology is a practical, highly illustrated guide written with the needs of the general dermatologist or gynaecologist in mind. The book begins with chapters on normal anatomy; history taking and examination of the vulva; biopsy taking and general management options. Next, symptom-based chapters describe presenting problems such as pruritus, broken skin and scarring, using flowcharts to help the physician work through to a diagnosis. Finally, chapters devoted to key conditions (lichen sclerosus, lichen planus, etc) describe the pathogenesis, clinical presentation, differential diagnosis and management of the disease in question. Abundantly illustrated and written in a practical, clinically oriented style, Gynecologic Dermatology is an indispensable reference for non-specialists that bridges the gap between dermatology and gynaecology. Symptom-based section reflects how patients present in real life and provides algorithms/flowcharts to help with diagnosis Includes second-line treatment options to help physician when standard treatment is unsuccessful Lavishly illustrated with over 500 photos, diagrams, tables and boxes

'Essential reading for everyone' - Marian Keyes It's time for us to start talking about the menopause. Cracking the Menopause, from straight-talking broadcaster Mariella Frostrup and health journalist Alice Smellie, has all the information you need, delivered with characteristic wry humour. It's high time we renovated and elevated this life change. Despite the centuries of speculation and propaganda, we are not overheating or inherently cold, we are not hysterics or boiling vats of toxic poisons, we are not dried up or washed up, we are simply menopausal. In this no-holds-barred guide, Mariella shares her own journey through the menopause, along with the latest science, advice from leading experts and humorous illustrations - to provide an informative source of wisdom and enlightenment. Featuring case studies from women in every walk of life and all stages of their menopause journey, Cracking the Menopause opens up the conversation about an urgent topic that half the population will experience, but barely anyone is talking about. Designed to equip you with the knowledge to manage your symptoms from perimenopause onwards, this essential book separates the myths from the reality and offers expertise, hope and advice. 'I inhaled this book, it's fantastic. Women of all ages need to read it.' - Claudia Winkleman 'Mariella and Alice have just written one of the most important books of the year, bravo.' - Gabby Logan

Obesity epidemic is a global problem of the 21th century for women in reproductive age and also the obstetricians and pediatricians. There are influences of mother's prepragnancy and antepartal obesity, at delivery, for fetal programming and for maternal and fetal lifelong metabolism. The epidemiological results are important, but for the health care providers the skills for prevention of mother's obesity with all consequences are essential. Evaluated programms in nutrition and physical activity will be discussed.

Recent years have seen important advances in the technology and techniques available to surgeons performing gynecologic surgery as well as reconstructive of clinical pelvic procedures. These developments took place in a wide variety settings from regional teaching centers to private clinical facilities. In 1996, the leading investigators from around the world gathered to discuss the present status of pelvic surgery and adhesion prevention with a look toward the future of patient care. This volume contains the proceedings of that meeting: the Third Interna tional Congress on Pelvic Surgery and Adhesion Prevention. Each chapter in cludes the material presented at the congress as well as a timely update of the authors' latest research and clinical thinking. Presentation integrating basic and clinical science provide the basis for con sidering peritoneal repair after surgery including the interaction of growth factors and other biochemical messengers. Research has increased the understanding of mesothelial reepithelialization and has led to new surgical technologies to reduce adhesion fonnation. A state-of-the-art review of emerging surgical adjuvants for adhesion prevention is provided, including discussion of barriers, gels, and poly mers as well as "designer" drugs effective at modifying the peritoneal response to injury. Assessment of clinical outcome in a wide variety of gynecologic surgical procedures brings into focus the benefits available as a result of these new tech nologies."

Oncofertility integrates the two previously distinct fields of cancer treatment and fertility research and aims to explore and expand the reproductive future of cancer survivors. In order to achieve the goal of fertility preservation, the Oncofertility community must focus on communication and the way data is provided and received. Concomitant with the rapidly changing technology of Oncofertility, there have been radical shifts and advances in the way health educators and clinicians can produce and share information.As success rates of reproductive techniques such as egg freezing and banking continue to rise, providing increasing opportunities for young cancer patients to preserve their fertility prior to the onset of cancer treatments, communication among professionals in oncology, reproductive medicine, and psychosocial work, among others, becomes crucial, and clinical demand for Oncofertility information is expected to rise considerably.

"Oncofertility Communication" describes and addresses the myriad channels through which the multiple audiences involved in Oncofertility can be served with appropriate and accurate information about cancer-related fertility issues. The text answers frequently asked questions and provides invaluable insights to scientific and health care professionals about communication among the diverse Oncofertility audiences. It incorporates timely discussions about traditional and emerging electronic communication tools and discusses the impact of health care policy changes on the Oncofertility field. "

Polycystic ovary syndrome (PCOS) is a classic female infertility condition affecting an estimated 6-10% of all women, many of whom are unaware of the problem. A disease that affects women from adolescence to menopause, PCOS is the single most common endrocrinologic abnormality affecting women. This book is an edited collection of writings that comprehensively covers the disease, from diagnosis and epidemiology of PCOS to clinical evaluation.

Key Clinical Topics in Obstetrics and Gynaecology offers an indispensable and practical guide for exam revision and clinical practice. Written and edited by specialists with a wealth of experience, this book provides rapid access to the core topics in obstetrics and gynaecology. Each topic is written in a concise and easy-to-digest format, making this book an essential resource for exam revision and quick reference at the point of care. Over 100 topics presented in alpha order, from abnormality of the genital tract, to venous thromboembolism Effective exam revision for MRCOG Part 2 candidates Succinct coverage of clinical features, diagnosis and patient management Includes clinical photos and diagrams to improve understanding of concepts Contributions from experienced specialists to ensure authoritative, accurate content

Pelvic Inflammatory Disease is an in-depth, thorough guide for the clinician on the most common complication of sexually transmitted pathogens. Edited and written by the preeminent experts in the field, this volume presents the etiology, treatment, and diagnosis of PID, as well as chapters on risk factors, epidemiology, and prevention. In addition, the myriad clinical complications and challenges are discussed in chapters on tuboovarian abscess, PID and HIV infection, sequelae of PID, PID in adolescence, and PID in pregnancy. This is a must-have resource for obstetrician-gynecologists, primary care physicians, and all clinicians who provide health care to women of all ages.

Breastfeeding and Human Lactation, Sixth Edition is the ultimate reference for the latest clinical techniques and research findings that direct evidence-based clinical practice and research for lactation consultants and specialists. It contains everything a nurse, lactation consultant, midwife, women's health nurse practitioner, physician assistant, or Ob/Gyn needs to know about lactation care and science. Topics include placing breastfeeding in its historical context, workplace-related issues, anatomical and biological imperatives of lactation, the prenatal and perinatal periods and concerns during the postpartum period, the mother's health, sociocultural issues, and more vital information. With contributions from the foremost experts in the field, this leading resource contains a clear clinical focus with more than 2,000 research studies supporting the clinical recommendations found in the text. Furthermore, the updated Sixth Edition features new and additional case studies, expanded cultural content, inclusion of new regulations and guidelines, information on alternative medicine, and gender inclusive language. Breastfeeding and Human Lactation, Sixth Edition is also an excellent resource to prepare for certification and practice as an International Board Certified Lactation Consultant (R) (IBCLC (R)). The Navigate 2 TestPrep access code included with every new print copy unlocks access to practice and simulated tests, detailed rationales, and powerful data dashboards. Standalone access to Navigate 2 TestPrep is also available (ISBN: 978-1-284-18994-0).

Advances in technology now offer promising solutions to deal with the chronological aging of the cell, tissue or organ to synchronize its existence and its use. This book covers the developments in and benefits of the latest vitrification technology and its extensive applications in reproductive medicine. Protocols of gametes (oocyte and sperm), embryos, blastocysts and ovarian tissue cryopreservation have been reviewed by leaders in the field. In order to address the escalation in cross-border reproductive tourism entailing the transfer of reproductive cells and tissues rather than the patient, the challenges, caution and emerging possibilities of nitrogen vapor shipment of vitrified cells have been discussed. Current perspectives on oocyte banking present the reader with options and solutions to effectively utilize these gametes despite the physiological deterrents.The versatile applications and potential of vitrification of human embryonic stem cells, discussed in the concluding chapter, is an exciting reality offered by vitrification to help overcome numerous stumbling blocks in the management of various disorders.

The editor of this volume takes on the challenging task of presenting an encompassing view of childbirth in America from an anthropological perspective. The book is indeed comprehensive. . . . Collectively the chapters in Childbirth in America lay out a representative sketch of research problems of interest to sociocultural anthropologists and other social scientists working in the area of reproductive health. A distinct accomplishment is the acknowledgement in some of the chapters that not all American women want the same kind of childbirth care or have the same values and attitudes about pregnancy, birth, and parenting, and that this variation needs addressing in both childbirth policy and practice. American Journal of Physical Anthropology A comprehensive and critical examination of the experience of childbirth in America today, from pregnancy to early postpartum. This book covers many controversial issues in the context of diverse cultural, social, and economic backgrounds, which have arisen as a result of the new technologies and ideologies surrounding pregnancy and birth. Most useful as a text for courses in childbirth education, anthropology of women's health, and anthropology of medicine.

The subject matter of volume 2 of the 2-volumes-handbook focusses especially on rare sarcomas of the whole female genitalia. These entities include angiosarcoma, the different lipo- and rhabdomyosarcoma as well as newer entities like the PEComa. Furthermore, mixed mullerian tumors like the benign adenofibroma and the malignant adenosarcoma and carcinosarcoma are described in detail. The book provides a description at length of the epidemiology, etiology, pathological anatomy, prognosis, diagnosis, differential diagnosis, imaging and comprehensive therapy of each primary, relapsed, and metastasized tumor including surgery, chemo-, hormone- and radio- and targeted therapy. An own chapter is devoted to the problems of fertility and pregnancy in connection with all sarcomas, variants of leiomyoma, atypical smooth muscle tumors, disseminated peritoneal leiomyomatosis, benign metastasizing leiomyoma, intravenous leiomyomatosis and endometrial stromal tumors - endometrial stromal nodules, endometrial stromal tumor with sex cord-like elements (ESTSCLE), uterine tumor resembling ovarian sex-cord tumor (UTROSCT) -and all mixed tumors - of the female genitalia. The book aims to identify and provide diagnostic and therapeutic guidance. The listed tumor entities also constitute a particular diagnostic challenge for pathologists that contains numerous pitfalls and difficulties. This book, therefore, addresses gynecologists and pathologists in both clinical and private practice, but also surgeons and hemato-oncologists.

As office technology has exploded and decision-making become increasingly complex, physicians are faced with an endless list of treatment options for commonly presenting gynecologic disorders. This new book reviews all state-of-the-art tools of diagnosis, investigation, and management to provide an invaluable guide for the office practitioner. From endocrine disorders to breast disease, from preventive measures for osteoporosis and cardiovascular disease to management of an abnormal pap smear, from the use of ultrasonography and minimally invasive diagnostic procedures to high-level endocrine manipulation, office-based physicians are expected to be knowledgeable in all areas. This book leads the way. For gynecologists and residents, here is a solid-foundation and ready reference source, enhanced by more than 60 detailed illustrations.

Das Buch ist ein Leitfaden fA1/4r die tAgliche Arbeit in GynAkologie, Geburtshilfe, Neonatologie und bei der genetischen Beratung.
Das Autorenteam geht auf alle sich im Rahmen der nichtinvasiven und invasiven PrAnataldiagnostik stellenden Fragen ein. Besondere BerA1/4cksichtigung findet die sonographische Fehlbildungsdiagnostik.
DarA1/4ber hinaus vermittelt der vorliegende Band fundiert und umfassend, aber dennoch A1/4bersichtlich den neuesten wissenschaftlichen Stand des fachA1/4bergreifenden Gebietes der Humangenetik. In dieser Funktion ist es fA1/4r alle in Klinik und Praxis mit der Diagnostik genetisch bedingter Erkrankungen und der genetischen Familienberatung BeschAftigten ein wertvolles kurzgefaAtes Nachlesewerk.

Since 2005 a dozen states and more than 15 specialties have reported a physician shortage or anticipate one in the next few years. This anticipated shortage and a worsening of physician distribution are compounded by a projected increased demand for women's healthcare services.

Women's healthcare is particularly vulnerable, because the obstetrician-gynecologist workforce is aging and is among the least satisfied medical specialists. Furthermore, fellowship training in women's healthcare in internal medicine and in maternal child health in family and community medicine involves only a small portion of general internists and family physicians.

In response to this challenge, the Association of American Medical Colleges called for an expansion of medical schools and graduate medical education enrollments. As we cope with significant and rapid changes in organizations and reimbursement, academic departments of obstetrics and gynecology, family and community medicine, and internal medicine have opportunities to create a unified women's health curriculum for undergraduate students, share preventive health and well-woman expertise in training programs, provide improved continuity of care, instill concepts of lifelong learning to our graduates, and better develop our research programs.

This volume's chapters focus on strategic planning on behalf of academic faculty who will train the anticipated additional load of students, residents, and fellows in women's healthcare.
-changing demographics of faculty
-expanding roles of clinician educators
-physician investigators and their future
-the hidden value of part-time faculty
-faculty salaries
-required skillsets of academic leaders
-the meaning of tenure and faculty satisfaction and retention.

Recommendations presented here from authors with distinguished leadership skills indicate a consensus, but not unanimity. In furthering these goals, we summarize in the final chapter our collective expertise and offer ways to implement recommendations to better prepare for tomorrow's needs in academic women's healthcare.