This issue will focus on the most common reproductive endocrine conditions encountered by healthcare providers. This series is timely and will be of interest to readers as there are many recent updates to the recommendations for appropriate evaluation and treatment of several reproductive conditions. Each chapter will address specific anatomic and hormonal conditions and will examine reproductive function from puberty to menopause. A thorough summary of abnormal uterine bleeding including recent 2012 updates for evaluation and management will be emphasized. Individual chapters on anatomic causes of bleeding, such as uterine fibroids and endometriosis, will be included with a focus on new treatment options. Polycystic ovarian syndrome (PCOS), a common hormonal cause of irregular bleeding and infertility, will also be reviewed. Recent studies provide insight into new fertility treatments for patients with PCOS including the use of aromatase inhibitors for ovulation induction. Other fertility related chapters include the evaluation of the infertile woman, ovulation induction, recurrent pregnancy loss, and age-related infertility. Finally, a transition to premature ovarian insufficiency and menopause will be provided. The Women's Health Initiative publication in 2002 reported an association between hormone replacement therapy and breast cancer. There are several updates since this controversial publication and recent literature will be summarized. Attention will focus on appropriate evaluation and management of these common reproductive endocrine topics reviewing recent recommendations on best practices for clinicians.

Lung disease affects more than 600 million people worldwide. While some of these lung diseases have an obvious developmental component, there is growing appreciation that processes and pathways critical for normal lung development are also important for postnatal tissue homeostasis and are dysregulated in lung disease. This book provides an authoritative review of fetal and neonatal lung development and is designed to provide a diverse group of scientists, spanning the basic to clinical research spectrum, with the latest developments on the cellular and molecular mechanisms of normal lung development and injury-repair processes, and how they are dysregulated in disease. The book covers genetics, omics, and systems biology as well as new imaging techniques that are transforming studies of lung development. The reader will learn where the field of lung development has been, where it is presently, and where it is going in order to improve outcomes for patients with common and rare lung diseases.

Healthy Babies Are Worth the Wait (R): A Collaborative Partnership to Reduce Preterm Births in Kentucky through Community-based Interventions 2007 - 2009 provides readers with an overview of the problem of preterm birth in the US, also describing in detail the design, implementation, evaluation, and outcomes of the Healthy Babies Are Worth the Wait initiative conducted in Kentucky between 2007 and 2009. The reader will learn about a unique research approach employing a mixed ecologic design that compared outcomes between intervention sites and comparison sites and the use of qualitative surveys and quantitative methods using state vital records data to evaluate outcomes. Consumer messaging and educational materials are discussed, along with the challenges of implementation and key lessons learned.

The Guests Editors have assembled expert authors to present clinical reviews on the current knowledge and best practices for high-risk pregnancies. Authors are writing on Genetics: update on prenatal screening and diagnosis; Screening for congenital heart disease; What you need to know when managing twins; Short cervix dilemma; preterm labor: approach to decreasing complications of prematurity; Optimizing outcomes for the growth-restricted fetus; Preeclampsia: short- and long-term implications; pregnancy risk associated with obesity; prevention of first cesarean delivery, and diagnosis and management of placenta accreta.

This issue of Medical Clinics of North America, Guest Edited by Joyce E. Wipf , MD is devoted to Women's Health. Dr. Wipf has assembled a group of expert authors to review the following topics: Breast Cancer Screening; Cervical Cancer and HPV; Oral Contraception; IUD and Other Contraception; Menopause; Cardiovascular Risk Factors and Disease in Women; Vulvar-vaginal Disorders; Hepatitis C in Women; Osteoporosis Screening, Prevention, and Management; Sexual Dysfunction in Women; Domestic Violence and Trauma; Care of Women Veterans; and Medical Conditions During Pregnancy.

This issue of Obstetrics and Gynecology Clinics of North America provides a summary of several more common maternal-fetal-infant infectious diseases. Several experts in the field of maternal and perinatal infection have contributed to this issue to provide an overview of the up-to-date preventive strategies, screening and diagnostic methods, and treatment guidelines. While guidelines such as universal vaccination to prevent influenza during pregnancy are fairly well justified by supporting data, there is much uncertainty about the appropriate screening guidelines for conditions such as cytomegalovirus, where the lack of a proven effective treatment diminishes the value of screening. Moreover, increasing issues of antibiotic resistance and the lack of significant advancement in developing newer effective agents imply that both providers and health care facilities must follow guidelines of antimicrobial stewardship (ie, coordinated efforts to improve and measure the appropriate use of antimicrobials). It is our hope that this issue will aid providers in navigating these complex issues while also understanding the current state-of-the-science

Despite the wide prevalence of urogynaecological problems, in clinical practice, there is a paucity of specialists that are skilled in the management of these conditions. The recognition of the need for a specialist to deal with these specific problems has led to the recent evolution of urogynaecology as a subspecialty. This book, Principles and Practice of Urogynaecology aims to equip the practicing professionals - Gynaecologists, Urogynaecologists and Urologists, with up-to-date information on the principles that guide the evaluation and management of pelvic organ prolapse and other common urogynaecological problems. With an emphasis on evidence based medicine, the book aims to deliver guidance on management of common urogynaecological problems and provides information on the latest cutting-edge surgical techniques. Written by global experts in the field of urogynaecology, the book focuses initially on pelvic floor anatomy and function, moving seamlessly to the evaluation and management of clinically relevant pelvic floor problems. A detailed discussion on management of mesh related complications is a highlight.

Breast Disease: Comprehensive Management provides a clear, concise source of information in order to make real-life, evidence-based decisions for all aspects of breast disease, both benign and malignant. The volume provides the latest breakthroughs in breast cancer research, ranging from paradigm shifts in the surgical management of the axilla, the changing role of adjuvant and neoadjuvant chemotherapy, the impact of molecular medicine in decision-making and the controversial role of prophylactic mastectomy in our era. Within select chapters, "How I do it" clinical scenarios are supplied and described in very practical terms. Also included at the end of each chapter are synoptic questions with detailed answers, akin to the self-assessment (SESAP) format questions and answers. These questions provide a basis for continuous medical education (CME) for the practicing physician and surgeon, further in surgical oncology and breast surgery, medical oncologists, radiation oncologists, and breast radiologists enhancing a focused approach to the management of breast disease in preparation for the American Board of Surgery certification and re-certification for the general surgeon. Breast Disease: Comprehensive Management is of great value to general surgeons, breast surgeons, surgical oncologists, general surgery residents, and fellows.

This issue of Obstetrics and Gynecology Clinics of North America attempts to provide an overview of the more common causes of chronic pelvic pain in women. It brings together experts in various fields of gynecology, gastroenterology, physical therapy, and urogynecology in an attempt to discuss the wide variety of common clinical conditions that can manifest as pain. The intent is to enable the physician to consider not only the common gynecologic causes but also the common nongynecologic causes based on certain symptom profiles and targeted clinical examination. Should the physician not feel comfortable in treating the nongynecologic causes, it would enable them to target their referral to a more appropriate physician rather than the patient being referred back to a general primary care physician. It is our hope that it will enable the reader to see the pelvis not as an ovary or a uterus but as a whole system of interacting organs, muscles, and nerves. In addtiion, there is very little in the Obstetrics and Gynecology literature about the treatment of the pain component with opioid and nonopioid medications. As one of my colleagues frequently states, we can treat the pain but not necessarily alleviate the suffering. The overview of complementary and alternative medications and opioid use will hopefully be useful to the practicing physician as it provides an evidence-based approach to the use of these therapies specifically for chronic pelvic pain.

This issue of Obstetrics and Gynecology Clinics of North America deals with the timely subject of substance use during pregnancy. Alcohol, tobacco, and illicit drug use is prevalent among reproductive-age women. Even though a reduction in use often occurs during pregnancy, many women continue to use substances until a pregnancy is either actually diagnosed or well underway.This issue consists of a well-qualified team of obstetricians-gynecologists, psychiatrists, and family physicians, focusing on various issues related directly to pregnancies complicated by substance use. Topics of interest include epidemiology and screening for hazardous and harmful substance use, teratogenic risks, psychiatric comorbidities, comprehensive treatment approaches before and after delivery, fetal surveillance, and team-based perinatal management. Particularly new information relates to prescribing buprenorphine, neonatal abstinence syndrome, and adolescent substance use.

This issue of the Obstetrics and Gynecology Clinics in North America will focus on the advances in the evaluation and management of Recurrent Pregnancy Loss (RPL) that have emerged within the last few years. Although spontaneous pregnancy loss occurs in approximately 15% to 20% of clinically recognized pregnancies in reproductive-aged women, RPL occurs in 2% to 5% of the same population. Recent reports on large populations of women with RPL have helped to characterize the incidence and diversity of this heterogeneous disorder, and a definite cause of pregnancy loss can be established on over 50% of all couples after a thorough evaluation. New diagnostic strategies, which include 23-chromosome microarray genetic testing of the products of conception in failed pregnancies, offer the promise of understanding the cause of most pregnancy losses. These recent advances, combined with the contributions from the authors in this issue of Clinics and many others interested in this field, lead to the publication of the long-awaited publication on evaluation and treatment of RPL from the Practice Committee of the American Society for Reproductive Medicine. A complete evaluation will include investigations into genetic, anatomic, immunologic, endocrinologic, and iatrogenic factors. "Generally the book is well written by internationally recognized and dedicated specialists, informative, updated and well-illustrated. I can recommend this book for physicians, scientists and also interested medical students who want to understand more about high risk early pregnancy." Reviewed by: Acta Obstetricia et Gynecologica Scandinavica, January 2015

Guest edited by Christopher Comstock of Memorial Sloan-Kettering, this issue of Radiologic Clinics will provide all of the latest guidelines and techniques for breast imaging. Modalities include MRI, MR-CAD, digital tomosynthesis, and ultrasound.

One out of every three women age 18-45 has experienced a reproductive loss. Women experiencing miscarriage often receive no explanation for the cause of their miscarriage. The lack of advice regarding the future and what can be done to avoid another miscarriage is too often the case.

"Miscarriage and the Successful Pregnancy" will provide insights and answers regarding miscarriage. William P. Hummel, M.D., a nationally recognized Fertility Specialist, states "A significant number of miscarriages can be prevented. A thorough fertility evaluation should give all couples options to maximize a full term pregnancy."

"Miscarriage and the Successful Pregnancy" provides the psychological support of this devastating condition and offers constructive steps to take with your physician. It is the authoritative guide to miscarriage treatment and success of your next pregnancy.

Gynecology is a procedure-related field that, like other specialties, has moved toward minimally invasive procedures that can be performed in the office setting. This issue of the Obstetrics and Gynecology Clinics covers the most commonly performed gynecologic procedures performed in the office setting. Colposcopy, Cryosurgery, LEEP, sterilization, D and C, and Urogynecologic procedures are all covered, along with articles on surgically implanted contraceptives and surgical abortion.

The Year Book of Obstetrics, Gynecology, and Women's Health brings you abstracts of the articles that reported the year's breakthrough developments in obstetrics, gynecology and women's health, carefully selected from more than 500 journals worldwide. Expert commentaries evaluate the clinical importance of each article and discuss its application to your practice. There's no faster or easier way to stay informed! Topics in this annual edition include obstetrics, reproductive endocrinology and infertility, and cancer/neoplasia.

This issue of Anesthesiology Clinics covers the latest updates in obstetric and gynecologic anesthesia written by the world-leading experts on the topic. Procedurally-focused articles cover best practices in chronic pain management, the role of magnesium in labor and delivery, advanced airway procedures, epidural analgesia, amniotic fluid embolism and more. Achieve the best outcomes and keep current on this area of anesthesia practice.

This issue of Ultrasound Clinics addresses obstetric? applications. Articles include U/S for Cervical length; Fetal ventriculomegaly; C/S scar ectopics; Skeletal dysplasias; Effects of obesity on obstetrical u/s imaging; Fetal lung; Abdominal wall defects; Fetal hydronephrosis; U/S for evaluation of fetal anemia; Training for Ultrasound Guided Procedures.

Guest edited by Bonnie Joe, this issue of MRI Clinics covers breast screening protocols, imaging the newly diagnosed cancer patient, imaging to monitor response to therapy, breast MR spectroscopy, and more.