'Maisie's knowledge of hormones changed my life... you need this book' Anna Jones 'Hill's advice is straightforward and no-nonsense' The Guardian 'An informative must-read for any woman - whatever their age' Vogue online During perimenopause three quarters of women will experience symptoms such as mood changes, insomnia, hot flushes, and night sweats, but there is little in the way of evidence-based information out there to help and guide us. Perimenopause Power is the essential handbook to understanding what the hell's going on and to empower us to improve our experience of the dreaded 'change'. Maisie Hill, the highly qualified women's health expert, best-selling author of Period Power and founder of The Flow Collective, takes us through the physiological changes of perimenopause and menopause, step by step, with calm positivity. In this invaluable guide she shares tips and advice to support women through the challenge of wildly fluctuating hormones. A must-read for anyone looking for a well-researched, evidenced-based book on perimenopause and menopause that gives women the information they need to address their hormonal needs. Perimenopause Power will help women to understand what's going on with their bodies and how to deal with troublesome symptoms, and share valuable insights into making it a positive and powerful experience. 'Maisie Hill helps you understand the changes in your body and psyche during the lead-up to menopause and how to handle symptoms.' Top Sante 'Maisie Hill gets rid of myths, sheds light and allows for an open, honest and much-needed conversation' Mind

approaches to the experimental problems that still face us in understanding this most fascinating of organs. Too many people contributed to the completion of this volume to allow acknowledg ment of all the individual efforts, but we particularly thank the reviewers whose input into the editorial process was invaluable and the authors of these chapters who revised their text, sometimes more than once, to bring it to the high standards set by the Editors. The Com mittee gratefully acknowledges the support ofVysis, Inc. , in the publication of a color figure in Chapter 19, by S. Weber-Hall and Trevor Dale. Finally, we wish to express our heartfelt appreciation to Margot Ip and Bonnie Asch, who worked long and hard to bring this volume to fruition. Margaret C. Neville for the Committee on Mammary Gland Biology Preface One of the most exciting and beneficial developments in research on mammary gland biology and breast cancer has been the influx of increased funding to support this work. This influx, which has been due primarily to the tireless efforts of breast cancer activists to gamer addi tional money from various federal and state sources, has led to a rapid expansion of research efforts by attracting numerous new investigators into the field. These new investigators include students, postdoctoral fellows, and scientists from other fields.

Many obstetricians do not have adequate skills to control hemorrhaging, transferring critically-ill mothers are suboptimal and infrastructural deficiencies have a profound impact on the outcome for the mother and the fetus. The chapters cover the technical, nontechnical and organizational skills and requirements needed to 'eliminate' morbidity and mortality related to obstetric hemorrhage. The authors are well-renowned for expertise in the area in which they have contributed the chapter. This book will help consultants, postgraduates and obstetric intensivists in updating their knowledge and skills. This book is a firm step forward to establish protocols and guidelines for developing countries. Contributors have been chosen carefully based on their work profile and experience. The chapters are crafted to elaborate on cost-effective newer technologies for management of obstetric hemorrahge. The book enhances skill and builds capacity for our fraternity in tackling matters of critical care in such patients.

Practical guide to diagnosis and management of infertility Step by step, algorithm-based approach Each topic presented on one page for easy reference Covers all aspects of infertility management, from basic to advanced procedures Highly illustrated with clinical photographs and flowcharts

Amenorrhea: A Case-Based Clinical Guide is a comprehensive review of the current knowledge regarding normal female reproductive physiology. Replete with interesting case vignettes and providing diagnostic algorithms and therapeutic strategies for amenorrhea, Amenorrhea: A Case-Based Clinical Guide is divided into three sections. The first section is composed of two chapters that provide a thorough review of basic science and clinical knowledge about the organ systems responsible for normal physiology of the menstrual cycle. The second section includes discussion about menstrual cycle disruption as it relates to hypothalamic-pituitary dysfunction, surgical and natural menopause, genetic defects, premature ovarian failure/insufficiency and the effects of caloric excess and restriction. The third section offers an update on the physiological effects of prolonged amenorrhea induced surgically or by hypothalamic dysfunction and also includes an original chapter that focuses solely on the impact of race and ethnicity on the prevalence and diagnosis of amenorrhea. Amenorrhea: A Case-Based Clinical Guide brings together chapters from renowned experts who offer state-of-the-art, clinically useful information in a case-based, reader-friendly fashion. This title will be a welcome addition to the bookshelves of all clinicians who practice in women's health settings.

A unique guide to operative decision-making techniques in female endoscopic pelvic surgery, this new edition is a landmark in the realm of gynecological endoscopy. It is divided into four sections: basics and anatomical aspects of endoscopic surgery, specific gynecological laparoscopic procedures, specific hysteroscopic procedures, and complications in laparoscopic and hysteroscopic surgery. After basic aspects in Section 1, the main chapters in Sections 2 and 3 deal with step-by-step laparoscopic and hysteroscopic surgery. The fourth section explains complication and is important for the management of the gynecologist whose surgical background may not include gastrointestinal or urinary tract surgery. Although the book has been written for gynecologic residents-in-training and practising gynecologists, it is also of use to general surgeons who perform gynecologic operations and to all physicians who perform ambulatory gynecologic procedures. Covers the entire gamut of gynecologic surgery. Provides practical advice on the correct implementation of the minimal invasive surgical procedures. Describes the anatomy, preoperative evaluation, surgical strategy, techniques and instruments, postoperative management, results, and complications. Interaction with urologists and general surgeons are detailed. Discusses injuries to the adjacent organs, such as bowel, urinary system, and pelvic vessels. Tips and Tricks have been provided for individual surgical procedures. Enriched with diagrams, tables and clinical photographs.

This is the ideal resource for keeping abreast new developments in the fast moving field. Written by expert authors and featuring topics such as hereditary cancer in gynaecology and caesarean scar ectopic pregnancy, each chapter highlights the latest developments of relevance to clinical practice. This book is an invaluable update and revision tool for trainees preparing for postgraduate examinations. Practical and clinically-relevant content enhanced by Key Points for Clinical Practice at the end of chapters. Chapters focus on important recent developments in the field of obstetrics and gynaecology. Effective revision tool for candidates sitting for postgraduate obstetrics and gynaecology examination.

This is an updated comprehensive guide about the latest developments in the field of ART. Eminent international experts have contributed their knowledge and practice protocols. Every chapter has been carefully written by respective authors who are paramount in the concerned subjects. This book endeavors to provide an in-depth insight into every aspect of reprodcutive technology. With a compilation of the most recent advances of infertility, the book stimulates its reader for future scientific research. The contributors involved are acknowledged pioneer in their respective fields. Includes experience-based treatment protocols. Take home messages provide the gist of the topics of each chapter. Ready resource for all practicing infertility experts, clinicians, embryologists and postdoctoral fellows, etc.

In the decade since the first edition of this work was published, an incredible array of reproductive technologies and associated issues has emerged. Obstetricians and gynecologists are hard-pressed to deal with the startling breadth and depth of these issues, which require mastery over a daunting combination of ever-increasing scientific knowledge, technical skills, long hours, legal liability, and exposure to clinical situations of overwhelming emotional intensity.

Psychiatrists have a vital role to play in helping obstetricians and gynecologists cope with a host of problems whose resolutions require not just technical skill, but also knowledge of biology, psychology, sociology, anthropology, ethics, and law. For example, to design and implement strategies to reduce the transmission of HIV, psychiatrists could work with public health workers to incorporate the psychology, sociology, and anthropology of female reproductive behavior. Psychiatrists could likewise improve the diagnosis and treatment of breast and pelvic malignancies by elucidating the factors that deter women from self-examination and regular medical screening and enhance treatment compliance.

Divided into three sections, this clinical and theoretical sourcebook addresses every major area of contemporary concern. - Pregnancy covers topics from the psychology of normal gestation to physical and psychiatric complications during and after pregnancy, including new prenatal diagnostic techniques and the dynamic issues that emerge when abnormalities are detected, and the use of psychotropic drugs and electroconvulsive therapy in pregnant and lactating patients.- Gynecology discusses not only common gynecologic problems but also more controversial issues such as induced abortion and the new reproductive technologies, including the role of the menstrual cycle in exacerbating and precipitating psychologic symptoms, the psychiatric aspects of menopause, the assessment and management of chronic pelvic pain, the psychosocial concomitants of gynecologic malignancies and the emotional demands on the oncology team, and the special implications of HIV/AIDS.- General Issues offers a broad, balanced view of topics rarely found in the literature, such as men's reactions to women's reproductive events, substance abuse and eating disorders, sexual and physical abuse (often part of the histories of patients with personality disorders and posttraumatic stress disorders), ethical and legal issues, and health care for lesbian patients. Of special significance is Dr. Stotland's chapter on how consultation-liaison services are provided to obstetrics and gynecology services.

This practical and scholarly volume is exceptionally useful as a teaching reference for medical and other health care students and residents in psychiatry and obstetrics and gynecology. It also provides a valuable resource for the clinician working to improve the psychological well-being of women patients.

The world's population is growing at an unsustainable rate. From a baseline ?gure of one billion in 1800, global population is predicted to exceed nine billion by 2050 and 87. 8% of this growth will be localized in less developed countries. Such uneven population growth will yield a harvest of poverty, malnutrition, disease and en- ronmental degradation that will affect us all. Amongst the complex mixture of political, social, cultural and technological changes needed to address this issue, the development of improved methods of fertility regulation will be critical. The inadequacy of current contraceptive technologies is indicated by recent data s- gesting that the contraceptive needs of over 120 million couples go unmet every year. As a direct consequence of this de?cit 38% of pregnancies are unplanned and more than 50% end in an abortion, generating a total of 46 million abortions per annum particularly among teenagers. If safe, effective contraceptives were ava- able to every couple experiencing an unmet family planning need, 1. 5 million lives would be saved each year (UNFPA 2003). Progress in contraceptive technology should not only generate more effective methods of regulating fertility, but should also provide a range of methods to meet the changing needs of the world's population. Contraceptive practice was revo- tionized in 1960 in the US and 1961 in Europe by the introduction of the oral contraceptive pill by Gregory Pincus, MC Chang and colleagues, based on fun- mental hormone research conducted in Germany.

For counselor Nancy Wainer Cohen, this book is the sibling to "Silent Knife: Cesarean Prevention and Vaginal Birth after Cesarean "(Bergin & Garvey, 1983) her critically-acclaimed expose on America's growing reliance on cesarean sections. "Open Season "provides fresh insights and new information on the subject, offering guidance to childbearing couples, educators, health professionals, and scholars who value the natural path of childbirth.

Readers will find this book timely, informative, shocking, irreverent, and extremely readable. Cohen's intimate writing style presents a compendium of knowledge on childbirth in the fashion of a personal letter. Her aim is to lower America's alarming reliance on cesarean section, which is currently at 25 percent of all births, and to return the responsibility for childbirth to women by encouraging them to choose the kind of birthing experience they wish to have. In addition to cesarean section, Cohen discusses many other generally unnecessary interventions performed on women during pregnancy and childbirth--such as fetal monitoring and routinized hospital procedures.

This book has been launched to commemorate the 24th Annual Conference of Indian Society for Assisted Reproduction. It is a unique effort to gather experiences from experts from all over the world - all of whom are authorities in their respective field, to provide concise and updated information and integrated management approach to deal with different situations.

This book is a simple guide to the diagnosis, investigation, and treatment of all gynaecological cancers. It discusses the management of patients with gynaecological malignancies; considers the principles of chemotherapy, radiotherapy, and surgery; explains when and why each modality is used in treatment; covers the pathology of gynaecological cancer; discusses treatment of the advanced disease; and includes a chapter on the role of palliative care. The multidisciplinary approach reflects the cooperative practice in combined clinics.

In recent years, the advancing science and increasing availability of assisted reproduction have given new hope to infertile couples. However, the use of IVF and ART has also led to marked increases in the number of multiple-infant live births. This poses a public health concern, as these neonates have a higher rate of pre-term delivery, compromising their survival chances and increasing their risk of lifelong disability. By optimizing the selection of gametes and embryos with high probabilities of implantation, it is possible to reduce the number of embryos transferred and, by extension, the number of high-risk multiple gestations, while maintaining or increasing pregnancy rates. Human Gametes and Preimplantation Embryos: Assessment and Diagnosis provides a broad yet concise overview of established and developing methodologies for assessment of gamete and embryo viability in assisted reproduction. This book elucidates the best practices for precisely selecting viable specimens based on morphology and cleavage rate and covers the spectrum of emerging adjunctive technologies for predicting reproductive potential. The authors present their extensive knowledge of "omics" approaches (genomics, transcriptomics, proteomics, and metabolomics), with unbiased delineation of the associated advantages and potential pitfalls. This valuable clinical resource is well suited to infertility specialists, Ob/Gyn physicians, IVF laboratory technicians, and researchers in the fields of embryology and reproductive medicine.

Aegean Conferences is an independent, nonprofit, educational organization directed and managed by the scientific community. The board is made up of nine researchers/scientists in various disciplines from Harvard, Brown, University of Pennsylvania, UCSD, Princeton, Biovista and the Foundation for Biomedical Research Academy of Athens. The board both invites and approves unsolicited proposals for Conferences in all fields of Science, Engineering, Arts, and Humanities. The purpose of the Conferences is to bring together individuals with common interests to examine the emerging and most advanced aspects of their particular field.

The Symposium on Ovarian Cancer: State of the Art and Future Directions intends to bring together international experts interested in the development of novel diagnostic, prognostic and therapeutic tools for ovarian cancer. The meeting will function as a think tank where clinicians, translational and basic scientists, and parties from the biotechnology and pharmaceutical industry will get together to review recent advances in clinical research and translational science in ovarian cancer and define areas of future research opportunities and priorities.

This book, part of the series Rare Diseases of the Immune System, offers comprehensive, up-to-date coverage of the pathophysiology and management of the antiphospholipid syndrome (APS). Immunologic and genetic aspects are discussed and the pathogenic mechanisms responsible for such phenomena as APS-mediated thrombosis and pregnancy loss/complications are explained. The main clinical manifestations, classification criteria and diagnostic tools are identified, and close attention is paid to the nature of the involvement of various organs or organ systems in APS. Specific chapters describe the treatment of the different symptoms, therapies of value in avoiding recurrences, and innovative treatment approaches. The authors are senior experts in the field who are aided by younger fellows, ensuring that the book is also educationally oriented. This handy volume will be a valuable tool for postgraduates in training and professionals wishing to extend their knowledge of this specific syndrome.

Peritoneoscopy and culdoscopy were first introduced in the second edition of TeLinde's Operative Gynecology in 1953. TeLinde noted, "In many instances we find peritoneoscopy to be a useful procedure. Nevertheless it often left something to be desired." During the subsequent four decades, enormous progress has allowed the expansion of the application of laparoscopy and hysteroscopy throughout gynecol- ogy. Thus, it is appropriate and quite useful to have a text devoted solely to this rapidly advancing specialty. In its second edition, the text Practical Manual of Operative Laparoscopy and Hys- teroscopy is a complete and honest overview of the field providing the reader with a critical appraisal of the current literature on technique, development, and long- term follow-up. Refreshingly, the authors include not only the American experi- ence but also advances from Europe and Asia. Ricardo Azziz and Ana Alvarez Murphy have carefully organized the text into general concepts and laparoscopic and hysteroscopic operative techniques. The editors have selected authors of national and international stature to prepare chap- ters in their areas of expertise. The edited text carefully analyzes the advantages and disadvantages of each operative technique so as to allow readers insight as to the proper place for a particular endoscopic technique in their surgical practices.

In this second volume, the Biennial Review of Infertility brings together the most up-to-date research and clinical information on male and female infertility, emerging assisted reproductive techniques, and controversial issues in reproductive medicine. This volume includes discussion of cutting-edge topics such as epigenetics, proteomics, and the role of the environment in fertility, as well as insightful evidence-based discussion of common clinical procedures. It is the cumulative effort of a preeminent panel of experts presenting each chapter in a clear and well-balanced manner. Created to provide an ongoing appraisal of current knowledge, the Biennial Review of Infertility stimulates communication amongst all those working to help couples resolve their infertility.

This is a book about the psychological journey women make when they become pregnant, give birth and adjust to life after childbirth. The focus of the book is on three main issues: The experience for women, their families and caregivers, the psychologicalneeds of women and their families at this time and the best way for caregivers to meet these psychological needs. The contributions in this book should provoke thought, discussion and debate about the psychological side of maternity care, and ultimately enhance the psychological care that is given to women and their families before, during and after childbirth.Multidisciplinary approach to subject Includes key points for caregivers in each chapter Includes new researdch findings fron qualitative and quantitative studies Includes comprehensive reviews of current literature

This compendium is an attempt to provide a precise and detailed outline of the many options available to young gynecologists (MD). It provides the latest information to today's trainees, including fellowship courses, short diplomas, international traveling courses, and superspecialty training and among others.

Ovarian cancer is the most lethal malignancy of the female reproductive system and is also the fifth leading cause of cancer death in women. Sharing common characteristics of cancer, ovarian malignancy possess several clinical and biological particularities In "Ovarian Cancer: Methods and Protocols," expert researchers in the field provide methods that have been created or adapted to study various aspects of ovarian cancer. These methods and techniques are applicable to study genetic alterations present in ovarian cancer, structural and metabolic features of ovarian cancer cells, include in vitro and in vivo models that recapitulate ovarian cancer development and progression, and describe ovarian cancer-oriented drug delivery approaches. Methodological chapters are grouped into seven thematic parts, any of them is introduced by short subject review. Written in the highly successful "Methods in Molecular Biology" series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls.

Authoritative and practical, " Ovarian Cancer: Methods and Protocols" seeks to aid scientist to optimize study designs, to correctly select the most applicable methods, and to produce interesting and novel results."

If there is one aspect of current cancer research that represents a major ch- lenge in both novice and experienced researchers, it is the rapid advance in our understanding of the disease. Researchers can be required to switch from analysis of gene expression to kinetics of protein activation, from genetic studies to the analysis of protein funtion. Cancers are highly complex disease systems and researchers aiming to understand the functioning of cancer systems require access to a wide range of laboratory techiques from a broad range of research disciplines. Increasingly, however, published methods are incomplete or refer back to a series of previous publications each containing only a small part of the complete pro- col. The aim of Ovarian Cancer: Methods and Protocols is to provide for ovarian cancer researchers in the first instance, a laboratory handbook that will facilitate research into cancer systems by providing a series of expert protocols, with proven efficacy, across a broad range of technical expertise. Thus, there are sections on tumor genetics and cellular signal transduction, as well as sections on apoptosis and RNA analysis. The value of Ovarian Cancer: Methods and Protocols to the ovarian cancer researcher will, I trust, be considerably enhanced by (1) the provision of a series of overviews relating to the biology, diagnosis, and treatment of this important neoplasm, and (2) the provision of a series of technical overviews introducing each part that provides an expert review of the applications and pitfalls of the various techniques included.