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The Immunology of Human Pregnancy (Hardcover, 1993 ed.)
Loot Price: R2,999
Discovery Miles 29 990
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The Immunology of Human Pregnancy (Hardcover, 1993 ed.)
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This book grew out ofmy interest in what is often called "the
immunological paradox ofpregnancy." How is it possible that the
fetus-halfofwhosegenetic apparatuscomesfrom thefather and is
foreign to the mother-can survive to term? This is a question that
intrigues all immunologists. For me, it has been of interest ever
since I heard a lecture on the subject in medical school, long
before I thought ofbecoming a "professional immunologist." Indeed,
the question ofthe immunological aspect of fetal survival (or
demise) should be of interest to any biologist or physician. The
question becomes broader ifone considers the immunologic relations
between motherand fetus, because they represent a unique symbiotic
union. Whatimmunologic problemsinthemothermayaffecttheoffspring,
and isitpossiblethatfetal immunology willaffectthe mother? Finally,
there is the question ofwhether immunology is important in recur-
rent spontaneous abortion. Every authorowes the reader a general
oversightofthe book in hand, indicating the terrain to be covered,
and, by inference, the territory that will not be explored. 1. This
is primarily a book for clinicians. I will only men- tion animal
experiments and data in passing, and as they may illuminate a
clinical problem or observation. 2. The interest here is the
immunology ofmaterno--fetal re- lations, once a pregnancy has
begun. Therefore, I will notcover immunological aspects
ofsterility, nor touch on the immunological approaches to
controlling fer- tility, i.e., "contraceptive vaccines." 3. This is
a book mainly concerned with pathogenesis.
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