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Regulation of the Contractile Cycle in Smooth Muscle (Hardcover)
Loot Price: R2,896
Discovery Miles 28 960
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Regulation of the Contractile Cycle in Smooth Muscle (Hardcover)
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At the Mie International Symposium held in Japan in April 1994,
leading scientists reviewed recent advances in the understanding of
the contractile mechanism in smooth muscle. The present volume
collects the papers presented at the symposium, summarizing the
latest advances in smooth muscle function and emphasizing important
components of the contraction-relaxation cycle. Topics include a
discussion of the smooth muscle cell membrane, with emphasis on its
ion channels; the regulation of cytosolic Ca2+ levels and the
relationship to force in smooth muscle; aspects of the two key
regulatory enzymes involved with myosin
phosphorylation-dephosphorylation; the molecular basis for
pharmacomechanical coupling in smooth muscle; developments in the
basic contractile mechanisms involving the crossbridge cycle of
tonic and phasic muscle; the role of myosin light chains; and many
others. The approach is broad and presents contemporary opinions in
pharmacology, physiology, and biochemistry as they relate to smooth
muscle function. The book will appeal not only to those working in
these disciplines, but to vascular clinicians,
obstetric-gynecological physicians, and gastroenterologists as
well.
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