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This book offers an image-based, comprehensive quick reference guide that will assist in the interpretation of contrast-enhanced ultrasound (CEUS) examinations of the liver in daily practice. It describes and depicts typical and atypical behavior of both common and less frequently observed focal liver lesions. For each type of lesion, the findings on pre- and post-contrast images are presented and key characteristics are highlighted. Individual chapters also focus on the assessment of response to locoregional and systemic treatment and the impact of European guidelines on CEUS. The Atlas of Contrast-Enhanced Sonography of Focal Liver Lesions will serve as an invaluable hands-on tool for practitioners who need to diagnose liver lesions using CEUS in the major clinical settings: oncology patients, cirrhotic patients, and patients with incidental focal liver lesions.
This book provides a comprehensive guide to the use of laparoscopic resection in the treatment of surgical liver lesions. As it introduces the steps and key techniques of laparoscopic anatomical liver resection, it will be of great interest to surgeons and physicians working in this area. Though each chapter covers a different technique, all chapters are written in a uniform style, including indications and contraindications, surgical steps, key techniques, complications and notes. This book provides readers with an overview of the current state of the art and deeper understanding of laparoscopic liver resections.
What if you could focus on one aspect of your well-being to transform all the others - and at the same time prevent health problems you didn't even know were lurking beneath the surface? In today's world, we have no idea how many symptoms, conditions, and diseases are rooted in an overloaded liver. It's not only about liver cancer, cirrhosis, and hepatitis. Nearly every challenge - from pesky general health complaints to digestive issues to emotional struggles to weight gain to high blood pressure to heart problems to brain fog to skin conditions to autoimmune and other chronic illnesses - has an origin in an overloaded liver and can improve and heal when you harness the force of this humble organ. Medical Medium Liver Rescue offers the answers you should have had all along. With his signature compassion, Anthony William, the Medical Medium, shares unparalleled insights into undiscovered functions of our lifesaving livers, explains what's behind dozens of health issues that hold us back, and offers detailed guidance on how to move forward so we can live our best lives. Find out for yourself what liver rescue is all about: being clearer-headed, more peaceful, happier, and better able to adapt to our fast-changing times. Learn how to sleep well, balance blood sugar, lower blood pressure, lose weight, and look and feel younger. A healthy liver is the ultimate de-stressor, anti-aging ally, and safeguard against a threatening world - if we give it the right support. "Anthony's understanding of foods, their vibrations, and how they interact with the body never ceases to amaze. Effortlessly he explains the potential harmony or disharmony in our choices in a way anyone can understand. He has a gift. Do your body a favor and treat yourself." - Pharrell Williams, 11-time Grammy-winning artist and producer
This book comprehensibly describes the clinical details of anatomic hepatic resection using the Glissonean pedicle approach for hepatocellular carcinoma. It includes all aspects of the surgical anatomy of the liver, preoperative management of patients, surgical techniques, and intraoperative key points to prevent postoperative complications. The first three chapters provide a general introduction to the clinical anatomy of the liver, preoperative management of patients with hepatocellular carcinoma, basic techniques for hepatic resection using the Glissonean approach, and the application of dye staining in anatomic hepatic resection. Subsequent chapters present the technical details of anatomical segmentectomy (Couinaud's classification), sectionectomy and hemi-hepatectomy for hepatocellular carcinoma using the modified suprahilar Glissonean approach. All of these hepatectomies can be performed using simple and easily available surgical instruments. In addition, it discusses precise transection of the deepest hepatic parenchyma guided by methylene blue staining. It is a useful and timely reference for hepatobiliary surgeons, clinical staff, and medical students.
Hepatobiliary and Pancreatic Surgery meets the needs of surgeons in higher training and practising consultants for a contemporary and evidence-based account of this sub-specialty that is relevant to their general surgical practice. It is a practical reference source incorporating the most current information on recent developments, management issues and operative procedures. The text is thoroughly referenced and supported by evidence-based recommendations wherever possible, distinguishing between strong evidence to support a conclusion, and evidence suggesting that a recommendation can be reached on the balance of probabilities. For this Sixth Edition the authorship team across the series has been expanded to include additional European and World experts, with an increased emphasis on global practice. Throughout all six volumes the contents have been extensively revised in line with recently published evidence. Detailed supportive key references are provided and are also included within the comprehensive list of references in the accompanying ebook. Links to recommended online videos have been added where appropriate. The Companion to Specialist Surgical Practice series provides a current and concise summary of the key topics within the major sub-specialties of general surgery. Each volume highlights evidence-based practice both in the text and within the extensive list of references at the end of every chapter. This edition of Hepatobiliary and Pancreatic Surgery includes new chapters on pancreas, islet and liver transplantation. The text includes new treatment options such as radioembolization, antiangiogenics and ALPPS, the latest guidelines on HCC and colorectal liver metastases management with recent evidence on treatment of biliary tract cancer, pancreatic cystic lesions and complicated acute pancreatitis. Over half of the chapters have been re-written by new authors thus ensuring that this edition is fresh, relevant and incorporates the latest developments and most up-to-date evidence base.
In daily medical practice, physicians often use scores, classifications and schematic diagnostic paths to make clear and comprehensive decisions. Treatment algorithms have also proven to be effective. However, it has become increasingly difficult or even impossible to have all scores, schemata and algorithms at hand, and a search on the internet can be very time consuming. Gastrix solves this problem: unlike classic gastroenterology and hepatology textbooks, it summarizes all necessary information in the form of a pocket-sized book. Gastroenterologists will thus have all relevant information easily available at all times.
Based on the results of studies on autoimmunity, the endocrine system, nutrients, metal metabolism and intestinal bacterial flora, this volume thoroughly covers studies on functional correlation of the liver with the spleen, visceral fat, intestinal tract, and central nervous system. Including associations with dysbiosis, nonalcoholic steatohepatitis (NASH) and hepatocellular carcinoma, it offers comprehensive data on correlations of organs with the liver from basic and clinical viewpoints. The Liver in Systemic Diseases will especially be of interest to researchers, clinical residents and medical students with an interest in hepatology and gastroenterology. Furthermore, the book has interdisciplinary appeal and provides a foundation that will help physicians to consider clinical conditions of diseases from a broader perspective.
This text covers all aspects of the current diagnosis and treatment of acute cholecystitis. Different diagnostic tests are discussed as well as the preoperative evaluation needed to initiate treatment. Other sections include the management of acute cholecystitis in the critically ill and elderly patients, recent advances in operative strategies that have further altered the treatment of acute cholecystitis, and the utilization of routine intraoperative cholangiography and its relative merits. Primarily intended for general surgeons and residents training in general surgery, Acute Cholecystitis will also serve as a comprehensive reference material for other health care providers, including primary care providers, mid-level nurse practitioners, emergency room physicians and medical students.
Pathology of Liver Diseases is a rapid reference consultation tool that uses both book and online material to present a whole range of liver disorders. The book emphasizes not only the pathology seen in biopsy and surgical material, but also the most pertinent clinical and laboratory findings including epidemiology, etiologic and pathophysiologic concepts, and the differential diagnoses. Key references appear at the end of each chapter. The book is also accompanied by a companion website: www.wiley.com/go/kanel/liverpathology It contains the following online material: * A complete Reference List. * A Library that contains over 860 images of the various liver diseases, which adds to over 540 images that are in the book itself * Additional Tables that address in detail the grading and staging of various liver diseases such as viral hepatitis and fatty liver diseases. *140 Case Examples, which include over 420 images that demonstrate the various ways many of these disease entities clinically present. * A PowerPoint presentation entitled "Liver Transplantation Surgical Procedure", which includes photographs from the operating table of the step-by-step process in liver transplantation. Pathology of Liver Diseases provides gastroenterologists and pathologists with a multi-media, well-illustrated, and concise guide to the pathology and clinical diagnoses of liver disorders.
Well-organized and vibrantly illustrated throughout, Handbook of Liver Disease is a comprehensive yet concise handbook providing authoritative guidance on key clinical issues in liver disease. The quick-reference outline format ensures that you'll find answers when you need them, and cover-to-cover updates keep you abreast of the recent rapid changes in the field. Written by leading international experts in hepatology, this reference is ideal for hepatologists, gastroenterologists, internists, family practitioners, trainees, and others who diagnose and manage patients with liver disorders. Uses a highly templated outline format, key points in each chapter, alert symbols, and highlighted review points to provide a "just the facts" approach to daily clinical questions on liver disease. Expert ConsultT eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, Q&As, and references from the book on a variety of devices. Features expanded hepatitis chapters, including completely updated coverage of new, safe, and effective oral regimens for the treatment of hepatitis C. Provides completely updated coverage of: alcoholic liver disease * autoimmune hepatitis * portal hypertension * primary biliary cholangitis * hepatic tumors * cirrhosis * nonalcoholic liver disease * liver transplantation * and more. Includes the latest information on adolescents with liver disease moving into adult care. Covers the revised criteria for prioritizing liver transplantation using the MELDNa score, new options for the treatment of hepatocellular carcinoma, and improved management of hepatorenal syndrome.
Algorithms provide a logical, concise and cost-effective approach to medical reasoning: utilizing a concise, step-by-step approach based upon clues from the history, physical examination and laboratory studies, algorithms help avoid excessive unnecessary procedures and testing. The 3rd, revised edition of Practical Algorithms in Pediatric Endocrinology deals with practical issues of child growth, puberty, diseases of the endocrine glands, sexual differentiation, as well as aberrations of water, electrolyte, mineral and carbohydrate metabolism. Fifty-six clinical issues are covered by an algorithmic approach, breaking down long lists and tables of differential diagnosis into smaller, more manageable ones. Common clinical symptoms, signs and laboratory abnormalities are classified as they present themselves at the patient's bedside. This book is aimed at general practitioners and pediatricians, in particular those who are not exposed to pediatric endocrine problems on a daily basis, and at trainees in endocrinology and pediatric endocrinology as they acquire familiarity with clinical problem solving to make rational choices when facing clinical dilemmas.
The liver is a complex organ due to its unique microscopic structure, intricate metabolic functions and susceptibility to a wide variety of insults, manifesting in countless histological patterns. "Atlas of Liver Pathology "considers both changes seen in medical liver biopsies as well as lesional biopsies when the specimen has been taken from a mass. The book starts by reviewing normal structure and its variants and the optimal approaches for the preparation of histological sections for diagnostic liver pathology. The following chapters are dedicated to developmental, metabolic, infectious, drug related, autoimmune, biliary, vascular and neoplastic disorders. Two sections on liver pathology in pregnancy and transplantation conclude the work. Macroscopic illustrations are included where appropriate. All photographs are complemented by legends describing the picture and providing relevant related information.
Authored by nationally and internationally recognized pathologists, "Atlas of Liver Pathology" is a valuable resource that serves as a quick reference guide for the diagnosis of usual and unusual diseases."
Stay up to date on today's most common GI and liver disorders and their management with GI/Liver Secrets Plus. This enhanced medical reference book is an excellent resource for understanding the physiology and therapy in hepatic and digestive disease. Whether preparing for an exam or quickly checking a clinical question, the user-friendly Secrets Series style makes this book a valuable addition to your library! Easily locate important information with bulleted lists, tables, boxes, short answers, and a highly detailed index to expedite reference. Access a broad range of topics that focus on all of today's most common GI and liver disorders and their management. Apply the latest knowledge and techniques with content thoroughly updated by leaders in the field. Quickly review key concepts with improved "Plus" formatting, which employs a Socratic Q&A approach designed to simulate the types of questions that may be used on patient rounds. Enhance your reference power through bulleted lists, mnemonics, "Key Points" summaries, lists of useful web sites, and practical tips from the authors. Improve content knowledge with a special chapter containing "Top 100 Secrets," providing an overview of essential material for last-minute study or self-assessment. Expert Consult eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, references, and videos from the book on a variety of devices.
This book thoroughly covers various diseases induced by portal hypertension, and introduces novel information for the treatment of patients. Individual chapters address the pathophysiology, diagnosis and treatment options available for the complications induced by portal hypertension. The book fosters practical understanding and provides more evidence-based treatment options in order to improve physicians' ability to select optimal treatment methods for their patients. Further, it offers readers the latest information concerning developments of the disease such as esophaogastric varices, ectopic varices, portal thrombosis, refractory ascites and hepatic encephalopathy. Clinical Science of Portal Hypertensions is an indispensible resource for both beginning and experienced gastroenterological physicians, endoscopists, liver physicians, radiologists, gastroenterological surgeons, liver surgeons, etc. who treat patients with portal hypertension on a clinical or research basis.
Whereas other textbooks mix a clinical approach with large amounts of the basic science of gastroenterology, this book concentrates on providing practicing gastroenterologists with 100% clinically focused, evidence-based chapters on how to correctly diagnosis and treat all disorders of the digestive tract. Once again, the book is divided into 4 clear parts: Symptoms, Syndromes and Scenarios; Diseases of the Gut and Liver; Primer of Diagnostic Methods; and Primer of Treatments. An accompanying website contains more than 85 high-definition surgical videos of diagnostic and therapeutic endoscopic procedures, 300 MCQs written to mirror the American College of Gastroenterology postgraduate course exams, more than 35 management protocol charts for different diseases, and 850+ illustrations for use in scientific presentations.
This book presents research outcomes, providing a big picture of rheumatic diseases as systemic conditions, and exploring the correlation between liver dysfunction and gastrointestinal lesions. Each chapter presents the association between major rheumatic diseases and hepato-gastrointestinal lesions, including liver and gastrointestinal involvement in lupus erythematosus, dermatomyositis, systemic sclerosis, Bechet's disease, and IgG4-related disease. The chapters on PBC-CREST syndrome and immunosuppressive agents broaden readers understanding and enable them to view the diseases from a systematic perspective. Although the disease is rare, it has attracted considerable attention as an intractable disease, and despite the severity of the symptoms, little has been written on the topic. Adopting a multidisciplinary approach, this comprehensive volume thoroughly prepares readers for research in the field of systemic diseases. Gastrointestinal and Hepatic Manifestations of Rheumatic Diseases is a valuable resource not only for hepatologists and rheumatologists, but also clinical residents and medical students.
The incidence of primary and metastatic liver tumors is rising and the therapeutic armamentarium for these tumors is expanding at a rapid pace. Surgery remains the primary treatment modality for these tumors. With improvements in our perioperative management and operative techniques a larger proportion of patients are able to undergo potentially curative liver surgery. In addition, indications and criteria for liver transplantation for both primary and metastatic liver tumors are constantly expanding. Unfortunately, many patients are not amendable to surgical resection or liver transplantation and therefore alternative liver-directed therapies are routinely being implemented as part of complex multidisciplinary treatment models. However, these models are continually evolving as these regional therapeutic options continue to expand. New embolization agents and techniques, as well as, improvements in radiation delivery, are all evolving in the background of improvement in systemic and targeted therapy options for these tumors. This book provides a comprehensive, state-of-the art review of the current state of liver-directed therapy for malignant liver tumors. The book will serve as a valuable resource for not only surgeons and clinicians but for researchers with an interest in malignant liver tumors. The book focuses on the therapeutic approach to primary and metastatic tumors providing an up-to-date review on surgical liver anatomy and new imaging techniques as well as patient selection and technical consideration for resection and transplantation. In addition, the book provides new insight into novel and evolving therapies in the areas of transarterial therapy such as: (i) bland embolization, (ii) chemoembolization, and (iii) radioembolization; as well as new radiation techniques including SBRT and proton therapy. Furthermore, the expanding role of hepatic artery infusion therapy in primary malignant tumors is highlighted. Finally, integration of all these regional therapy options with upcoming and evolving systemic and targeted therapy regimens are integrated and discussed. This book will serve as a very useful resource for clinicians and researchers managing and treating patients with these challenging malignancies. It provides a concise yet comprehensive summary of the current status of the field that will help guide patient management and stimulate investigative efforts. All chapters are written by experts in their fields and include the most up to date scientific and clinical information.
Radiology Illustrated: Hepatobiliary and Pancreatic Radiology is the first of two volumes that will serve as a clear, practical guide to the diagnostic imaging of abdominal diseases. This volume, devoted to diseases of the liver, biliary tree, gallbladder, pancreas, and spleen, covers congenital disorders, vascular diseases, benign and malignant tumors, and infectious conditions. Liver transplantation, evaluation of the therapeutic response of hepatocellular carcinoma, trauma, and post-treatment complications are also addressed. The book presents approximately 560 cases with more than 2100 carefully selected and categorized illustrations - along with key text messages and tables - that will allow the reader easily to recall the relevant images as an aid to differential diagnosis. At the end of each text message, key points are summarized to facilitate rapid review and learning. In addition, brief descriptions of each clinical problem are provided, followed by both common and uncommon case studies that illustrate the role of different imaging modalities, such as ultrasound, radiography, CT, and MRI.
Since its first publication more than 35 years ago, MacSween's Pathology of the Liver, by Drs. Alastair D. Burt, Linda D. Ferrell, and Stefan G. H bscher, has established itself as the definitive reference on liver pathology. The 7th Edition continues the tradition of excellence with more than 1,000 high-quality illustrations, coverage of the new and emerging diagnostic applications and techniques that pathologists must be familiar with, an up-to-date review of drug-induced injury, and much more. A must-have for every surgical pathologist, MacSween's remains the most authoritative and comprehensive book in its field. Provides comprehensive, state-of-the-art coverage of all malignant and benign hepatobiliary disorders from an international "who's who" in the field. Helps you quickly recognize the wide variety of liver appearances that result from infections, tumors, and tumor-like lesions, as well as organ damage caused by drugs and toxins. Features 1,000+ full-color illustrations that provide a complete visual guide to each tumor or tumor-like lesion and assist in the recognition and diagnosis of any tissue sample you're likely to encounter. Incorporates relevant data from ancillary techniques (immunohistochemistry, cytogenetics, and molecular genetics), giving you the tools required to master the latest breakthroughs in diagnostic technology. Includes an updated chapter on mechanisms of liver disease, including coverage of regression and remodeling of disease and new information on next generation sequencing; an up-to-date review of drug-induced injury, including the effects of herbal and alternative medicines. Expert ConsultT eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, Q&As, and references from the book on a variety of devices.
Clinical Dilemmas in Non-Alcoholic Fatty Liver Disease offers hepatologists practical, up-to-date and expert guidance on the most topical dilemmas, difficulties and areas of controversy/difficulty surrounding this ever-increasing area of liver disease they face in daily practice. Roger Williams and Simon Taylor-Robinson, two of Europe s leading hepatologists, have recruited leading figures from across the world to assist them, resulting in a truly international approach. Each chapter covers a specific area of difficulty, containing clear learning points and providing evidence-based expert guidance on the latest hot topics in clinical management such as: * Is NAFLD different in absence of Metabolic Syndrome? * Are the pros outweighed by the cons of obtaining a liver biopsy? * Is progression to cirrhosis more likely in children with NAFLD? * What are the dangers as well as the true benefits of bariatric surgery? * How is it best to use antifibrotic agents in clinical practice? Clinical Dilemmas in Non-Alcoholic Fatty Liver Disease provides the answers to the questions and challenges that clinicians face every day in this area. It is essential reading for hepatologists of all levels and researchers in hepatology, as well as all those involved in the care of patients with NAFLD, including gastroenterologists, pathologists and specialist hepatology nurses.
Autoimmune Liver Diseases summarizes the recent high-impact research and clinical findings obtained in Japan in the study and treatment of autoimmune liver diseases. Although these disorders are relatively rare, they are recognized as an important group of refractory liver diseases, the most common of which are autoimmune hepatitis (AIH) and primary biliary cirrhosis (PBC). The book therefore comprises two major sections, one dealing with AIH, the other with PBC. AIH in Japanese patients creates a unique disease population, as its clinical features are different from those of Western patients resulting from the different genetic background of the two patient populations. Also, mouse models of neonatal thymectomy-PD-1 knockout mice, clinical analyses of acute hepatitis-like manifestations, and research findings on IgG4-related autoimmune hepatitis have been reported in Japan and are included in this book. A disease-susceptibility gene specific to Japanese PBC patients has also recently been discovered. Because of the relatively homogeneous population of Japan, analyses conducted with Japanese PBC patients have yielded findings that are highly relevant to the pathogenesis of the disease. Furthermore, new pathological staging criteria, anti-gp210 antibodies and the basis they provide for improved accuracy of prognosis, treatment with bezafibrate, and the outcomes of living-donor liver transplantation are also presented here. This volume therefore serves as a useful resource not only for hepatologists, but also for researchers, clinical residents, and medical students both in Japan and in other countries.
Receiving a liver cancer diagnosis is a difficult experience, and leaves patients and their caregivers feeling anxious and overwhelmed. What is liver cancer? What are the treatment options? What are the sources of support? The only text to provide both the doctor's and patient's point of view, 100 Questions & Answers About Liver Cancer, Fourth Edition provides authoritative, practical answers to these questions, and many more. Written by a medical oncologist and a gastrointestinal surgeon, this updated fourth edition provides a comprehensive discussion of what you can expect post-diagnosis along with patient commentary to give you a real-life understanding of what these steps might mean for your day-to-day life. This book is an invaluable resource for anyone coping with the uncertainty of a liver cancer diagnosis.
Featuring 137 carefully selected cases, this atlas covers virtually every aspect of clinical cross-sectional imaging of the liver, gallbladder, biliary system and pancreas. For the vast majority of the cases, both CT and MR images are included to demonstrate the different features of each lesion. Furthermore, both typical and atypical pathologies are included to facilitate the differential diagnosis in daily clinical practice. Concise yet comprehensive,this atlas includes not only imaging features of the lesions but also the related pathologic and clinical data. It is therefore useful both as a quick guide for practicing radiologists and as a brief textbook for radiologists in training.
This clinical casebook provides a concise yet comprehensive state-of-the-art review of liver disease. Presented in a case-based format, each case features a scenario centered on a different variant of liver disease, with sections on case history, diagnosis/assessment, treatment, outcomes, alternative approaches, and clinical pearls. Diseases covered include drug-induced liver injury, acute hepatitis, chronic hepatitis, NAFLD, and cholangitis. Scenarios such as liver disease in pregnancy, elevated liver function tests, and liver transplants are also presented in the casebook. Written by experts in the field, Liver Disease: A Clinical Casebook is a valuable resource for clinicians and practitioners who treat patients with liver disease.
Hepatology is an important specialty with diseases and complications related to viral hepatitis and alcohol being the main reason for seeking specialist advice. On most general medical rotations and on most surgical wards there are patients with hepatological problems. "Hepatology: Clinical Cases Uncovered" contains clinical presentations with real-life patient cases and outcomes as seen on the wards and in exams, and leads students through a practical approach to diagnosis and management of hepatological disease.
Following a question and answer approach, including self-assessment material and a 'refresher' section on the basic science, "Hepatology: Clinical Cases Uncovered" features investigations and the treatment options available for patients presenting with hepatological problems. Difficult concepts are clarified and relevant links are made between pathology and clinical presentation.
"Hepatology: Clinical Cases Uncovered" is ideal for medical students, junior doctors on the Foundation Programme, GP trainees, residents, specialist nurses and nurse practitioners. The book is also an ideal refresher for hepatology or gastroenterology trainees at the beginning of their specialist training programme
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