Liver, Biliary Tract and Pancreas, 2nd Edition, part 3 in the 3-book Digestive System volume, provides a concise and highly visual approach to the basic sciences and clinical pathology of the hepatobiliary system and pancreas. This book in The Netter Collection of Medical Illustrations (the CIBA "Green Books") has been expanded and revised to capture current perspectives in hepatology, pancreatology, and gastroenterology - from normal anatomy and physiology through pathophysiology, diagnostics and treatment of the liver, pancreas, and biliary tract. It also features radiologic and pathologic images to supplement the classic Netter illustrations, as well as new illustrations. This this updated classic is ideal for students and health professionals seeking an easily accessible guide to the digestive system. Put concepts into practice. An exquisite art program that focuses on clarity of presentation with an emphasis on anatomy, pathology, patient presentation, and clinical context. Gain a rich, comprehensive overview of the liver, pancreas and biliary tract by seeing classic Netter illustrations side by side with cutting-edge radiologic and laparoscopic images. Explore key topics, including tumors of cirrhosis, portal hypertension, pancreatitis, liver lobectomy and transplantation, and cholescystectomy. See modern issues in digestive health and disease captured in the visually rich Netter artistic tradition via contributions from artists working in the Netter style. Get complete, integrated visual guidance on the hepatobiliary system and pancreas in a single source, from basic sciences and normal anatomy and function through pathologic conditions. Benefit from the knowledge of a team of renowned clinicians and scientists.

Hepatology at a Glance is an accessible, illustrated introduction to this increasingly important specialty. This brand new title helps the reader to develop a solid understanding of liver disease, and to recognise, diagnose and treat all types of routinely encountered liver and biliary disorders. It covers key areas such as the development, structure and function of the liver, transplantation, surgery and nutrition. Common cases of liver disorders and scenario, and the management of rarer diseases and disorders in special patient groups such as the pregnant are included. Hepatology at a Glance: Is a unique and concise resource on hepatology created for junior medical staff Maintains a practical emphasis, with advice on history, examination and clinical testing Includes clinical scenarios, with self-assessment questions and full explanations to answers Follows the curriculum set by and with the support of the British Society of Gastroenterology Includes a companion website at www.ataglanceseries.com/hepatology featuring 30 MCQs Providing guidance on all vital aspects of the specialty, Hepatology at a Glance is a succinct and accessible summative resource to enable a thorough understanding of the field.

Cardio-Hepatology: Connections Between Hepatic and Cardiovascular Disease provides a direct relationship between the cardiac and hepatic pathologies providing the link between the heart and liver and showing how liver diseases predispose to impairment in heart functioning and vice versa. Considering the growing number of patients living (and living longer) with heart failure and/or congenital heart disease, it is important to know when and how to test for liver disease in this population, how to interpret abnormal test results, and what management is appropriate. Coverage includes what should be done for patients to limit, avoid, or postpone the impairment in the liver functioning induced by heart diseases and the impairment in the heart functioning induced by liver diseases, on the basis of scientific-exposed evidence and pathophysiology knowledge. This comprehensive, extended review of the medical literature is perfect for researchers interested in the connection between cardiology and hepatology as well as clinicians making therapeutic decisions for patients suffering from heart or liver chronic diseases.

The recently published article "The Burden of Liver Disease in Europe: A Review of Available Epidemiological Data" provides a few figures on the enormous problem that liver disease poses for Europeans. Liver disease is estimated to cause 170,000 deaths annually in Europe, 47,000 of which are attributed to liver cancer; 0.5%-0.7% of the European population is affected by chronic hepatitis B; and prevalence rates of hepatitis C virus (HCV) infection in the last decade in the European population ranged from 0.13 to 3.26%. These HCV-infected populations will develop complications in the years to come. It is of great concern that about 90% of people in Europe infected by viral hepatitis are unaware of their status. Alcoholic and non-alcoholic fatty liver disease (NAFLD) must also be added to the picture. NAFLD is becoming a major concern with the increasing incidence of obesity and type 2 diabetes in Europe. The burden of liver disease is not less pessimistic in North America, Asia and the rest of the world.

Containing a selection of teaching tools for general anatomy and pathology, this work, with flip charts, offers an overview and understanding of the subject matter. It is useful for student or patient education. It is suitable for the home, the school library, or the physicians office and can be written on by a dry marker.

This book comprehensibly describes the clinical details of anatomic hepatic resection using the Glissonean pedicle approach for hepatocellular carcinoma. It includes all aspects of the surgical anatomy of the liver, preoperative management of patients, surgical techniques, and intraoperative key points to prevent postoperative complications. The first three chapters provide a general introduction to the clinical anatomy of the liver, preoperative management of patients with hepatocellular carcinoma, basic techniques for hepatic resection using the Glissonean approach, and the application of dye staining in anatomic hepatic resection. Subsequent chapters present the technical details of anatomical segmentectomy (Couinaud's classification), sectionectomy and hemi-hepatectomy for hepatocellular carcinoma using the modified suprahilar Glissonean approach. All of these hepatectomies can be performed using simple and easily available surgical instruments. In addition, it discusses precise transection of the deepest hepatic parenchyma guided by methylene blue staining. It is a useful and timely reference for hepatobiliary surgeons, clinical staff, and medical students.

This book will be an affordable, highly practical handbook on hepatology, aimed at residents/trainees in gastroenterology, GI nurses, and recently qualified consultants to use as a quick reference when managing patients presenting with possible or overt liver disease.

It will be of particular use for those GI internists/residents who have an interest specifically in hepatology. It does not aim to be a specialist textbook, but a shorter, 250pp guide that provides key clinical information on each area of hepatology in an accessible form. Extracting relevant material from large reference textbooks can be very time consuming and for this reason, information in this handbook will be presented succinctly in a style suitable for quick reference and easy understanding.

The chief emphasis will be on the clinical assessment and management of these patients, and all the major areas of liver disease will be covered, from liver cirrhosis to viral hepatitis, to autoimmune liver failure.

Chapters will use a variety of structural features and colour coded boxes to increase the accessibility for residents. These include: key points/take-home points, case history, practice points and management algorithm/flow-charts. Each chapter will also contain sample multiple choice questions that the reader will be able to test themselves on.

This field has shown tremendous growth in recent years, primarily due to the recognition that drug-induced liver disease is the most common cause of liver failure and one of the major contributors to the withdrawal of drugs developed by the pharmaceutical industry. Drug-Induced Liver Disease, 3rd edition is a comprehensive reference that covers mechanisms of injury, diagnosis and management, major hepatotoxins, regulatory perspectives and much more. Written by highly respected authorities, this new edition is an updated and definitive reference for clinicians and scientists in academia, the pharmaceutical industry and government settings. This book contains 4 new chapters on key topics in the area and provides a current and extensive review of the latest developments concerning the toxicology, pharmacology, genetics and immunology of drug-induced liver disease.

A multi-authored reference work written by leading clinical, academic and industry experts in drug-induced liver disease.

Contains four new chapters on key areas in the field, including one on worldwide drug-induced liver injury networks.

Each chapter has been updated to address the latest research and findings in the field and 16 new chapter authors have been added to this new edition.

Includes coverage of the basic, clinical and practical aspects of drug-induced liver disease to provide the single most comprehensive reference on the subject. "

Gastroenterology and Hepatology Lecture Notes is a comprehensive yet easy-to-read overview of luminal gastroenterology and hepatology. Covering the epidemiology, causes, clinical features, investigation, treatment and prognosis of all the main gut and liver conditions, it is ideal for both exam preparation and fact finding. Key features include: A full range of new illustrations, including clinical photographs and scans, that clearly demonstrate signs and symptoms Sections on anatomy, physiology, pharmacology, and epidemiology written to enhance understanding of clinical features Essential information highlighted throughout the text Case-based self-assessment for each chapter helps retention of knowledge and puts it in its clinical context A new section of best answer MCQs New chapters on inflammatory bowel disease and different diagnosis of the upper GI tract Includes a companion website at www.lecturenoteseries.com/gastroenterology featuring 16 in-depth case studies Whether learning the basics of the gastrointestinal system, starting a general medical or gastroenterological placement, or looking for a quick-reference overview to revise key concepts, Gastroenterology and Hepatology Lecture Notes is an ideal resource for medical students, MRCP or FRACP candidates, and junior doctors.

Hepatology is an important specialty with diseases and complications related to viral hepatitis and alcohol being the main reason for seeking specialist advice. On most general medical rotations and on most surgical wards there are patients with hepatological problems. "Hepatology: Clinical Cases Uncovered" contains clinical presentations with real-life patient cases and outcomes as seen on the wards and in exams, and leads students through a practical approach to diagnosis and management of hepatological disease.

Following a question and answer approach, including self-assessment material and a 'refresher' section on the basic science, "Hepatology: Clinical Cases Uncovered" features investigations and the treatment options available for patients presenting with hepatological problems. Difficult concepts are clarified and relevant links are made between pathology and clinical presentation.

"Hepatology: Clinical Cases Uncovered" is ideal for medical students, junior doctors on the Foundation Programme, GP trainees, residents, specialist nurses and nurse practitioners. The book is also an ideal refresher for hepatology or gastroenterology trainees at the beginning of their specialist training programme

Signaling Pathways in Liver Diseases, Third Edition again provides hepatologists and hepatology researchers with an expert overview of the complex and novel cellular/extracellular signaling pathways in the liver, and their role in liver diseases. The last few years have seen a great number of developments in this field, which in turn have led to new opportunities for innovative treatments; however, the intricacy of these pathways and their interactions continue to provide a real challenge for clinicians. This outstanding book compiles the emerging knowledge into a single expert resource, cataloguing and organizing it into an accessible and understandable format. With increased focus on the comprehension of cellular mechanisms involved in steatohepatitis, cirrhosis, and liver tumors, which has led to changes in the management of these diseases, this new edition also sees the introduction of exciting new chapters on key emerging areas such as: * Autophagy * Notch Pathway * P13K/PTEN Signaling in Liver Diseases * Sirtuins * Hepcidin and Iron * Epigenetic Regulation of Hepatic Stellate Cells and Liver Fibrosis * Oxidative Stress and Signaling in the Liver. Professors Dufour and Clavien have assembled an all-star cast of chapter authors, each of whom has provided clear and appropriate illustrations to reinforce the text, with a key points box offering a concise and handy summary. Self-assessment questions and answers allow the reader to test their own knowledge. Signaling Pathways in Liver Disease, Third Edition is the perfect educational and reference tool to bridge the information exchange between the laboratory, the clinical ward, and the operating room, and an essential tool for the modern-day hepatologist.

This book comprehensively covers the latest developments in the diagnosis and treatment of liver cirrhosis, including molecular mechanisms and therapeutic strategies. It elaborates on and explores the relation between chronic liver disease (CLD) and its causes, including viral hepatitis, steatohepatitis, autoimmune liver diseases and/or inherited liver diseases, and sustained liver injury. Furthermore, it discusses various complications such as hepatic encephalopathy, ascites, sarcopenia, esophagogastric varices, muscle cramps and pruritus, and the fact that it frequently leads to the development of hepatocellular carcinoma. CLD is becoming a growing issue with substantial effects on public health, and Evolving Landscape in Management of Liver Cirrhosis provides scholars in gastroenterology and hepatology with invaluable insights. At the same time, it is a valuable resource for clinicians specializing in gastroenterology and hepatology as well as for researchers who are curious about new research on liver disease.

The Understanding Hepatitis chart is a comprehensive overview of the different types of hepatitis, including symptoms, causes and treatments. External views of healthy and cirrhotic livers are shown, including a view of the liver lobules. Heavy cover stock with protective varnish for durability.

Hepatic hydatidosis is a worldwide disease with a high socio-economic cost in endemic areas. Until recently, only professionals working in these areas treated hydatidosis patients, but now, due to migration and increasing intercontinental travel, any medical doctor may have to attend to patients with hydatid disease. Therefore, proper training in the diagnosis and treatment of these patients is necessary, not just in endemic areas which already have extensive experience in managing the disease, but also in institutions in countries like the United States where hydatidosis is still rare. In this book, we update all the epidemiological, radiological, clinical and therapeutic topics in liver hydatidosis. The chapters are written by a multidisciplinary group of physicians involved in treatment of the disease: microbiologists, gastroenterologists, internists, radiologists and surgeons. We conduct a complete review of all the treatment options in hydatidosis, including antiparasitic drugs, PAIR and surgery.

Chronic Hepatitis C virus (HCV) infection is a serious condition affecting over 180 million people world-wide. The virus infects the liver and while it is estimated that 20% of those infected clear the virus spontaneously, the virus persists in the majority of individuals leading to liver fibrosis, cirrhosis, and hepatocellular carcinoma. This book presents topical research in the study of the epidemiology, pathogenesis and treatment of Hepatitic C Virus including: genome-wide association studies regarding HCV infection; hepatic and blood dendritic cell subsets in patients with chronic HCV; bone metabolism disorders in HCV infection; Socs1 involvement in liver damage during HCV infection; asymptomatic low-level HCV persistence; and HCV infection as the leading cause of liver disease in renal transplant recipients.

This book provides a comprehensive, state-of-the art review of current and new therapies in treating pancreatic cancer. In addition to discussing the current landscape for treating various stages of pancreatic cancer, the text highlights several standard and emerging approaches, with a particular emphasis on novel endoscopic, surgical, chemotherapeutic, radiotherapeutic, targeted, and immunotherapeutic strategies. The volume also features concepts on the potential economic effects associated with the development and implementation of new treatments in pancreatic cancer. Written by experts from a variety of integrative disciplines, Current and Emerging Therapies in Pancreatic Cancer is a valuable resource for oncologists, gastroenterologists, surgeons, and other professionals who treat and manage patients with pancreatic cancer.

This title includes proceedings of the International Congress held in Chamrousse (France), 1-2 February 1991.

This volume provides the reader with a detailed overview of the current state-of-the art approach of Hepatitis C management. It reviews the course of action in handling of chronic Hepatitis C patients with various HCV genotypes and treats special cases such as acute hepatitis, transplant and renal patients as well as people who inject drugs. The two volume work on Hepatitis C introduces to the topic by reviewing virology, diagnosis, epidemiology, prevention, management and elimination of HCV. The book provides a valuable source at full length for researchers and clinicians working on Hepatitis C.

The treatment of bile duct benign pathology demands a multidisciplinary approach, involving a team of both specialised physicians and solid infrastructure. Radiologists, endoscopists, and surgeons are all involved in the treatment of these kinds of patients. This statement is also true for the diagnosis and treatment of the catastrophic results of bile duct injury. Cholecystectomy is one of the most common surgical procedures done either openly or through laparoscopy. The presence of bile duct injury is one of its most severe complications. The solution for this unfortunate event poses a technically demanding approach that involves an array of alternatives comprising surgical and radio-interventional procedures. This book focuses on benign bile duct diseases, mainly related to iatrogenic bile duct injury. The reader will find a complete and profound review of bile duct anatomy and function, a thorough explanation about the type of bile duct injuries and how to approach them, beautiful descriptions of both the surgical and radiological techniques used in the management of bile duct injuries, a compilation of the experience of a high-yield centre of this kind of diseases, and logical techniques to lower the incidence of these injuries. This text is aimed at an audience composed of health care professionals involved in the integrative treatment of iatrogenic bile duct injuries. In a world where the best medical evidence defines the most effective therapeutic alternative, this book focuses on giving a solid and broad enough basis upon which medical teams can approach this disease.

The Understanding Hepatitis chart is a comprehensive overview of the different types of hepatitis, including symptoms, causes and treatments. External views of healthy and cirrhotic livers are shown, including a view of the liver lobules. Heavy gauge 3ml lamination with sealed edges and two metal eyelets for hanging makes chart highly durable. Write-on/wipe-off with dry erase marker (not included).

This volume provides the most updated knowledge on the advancement of molecular pathogenesis, molecular diagnosis, and therapy development for hepatocellular carcinoma (HCC). Topics covered include the etiology and pathogenesis of HCC, recent advances in HCC genomics, biomarker discovery and validation in HCC diagnosis, the role of liver biopsy in HCC early diagnosis, and the future prospects of surgical approaches and targeted therapy for HCC. In addition to reviewing the current available knowledge, the book also discusses the future development of a precision and personalized medicine approach for HCC. Written by experts in the field, Precision Molecular Pathology of Liver Cancer is a concise yet comprehensive resource for practitioners who treat patients with hepatocellular carcinoma.

The second edition of this book is intended as a definitive text on biliary tract and gallbladder cancers. Specifically, it will serve as a single-source reference on the current knowledge base for the multidisciplinary management of such cancers and thus covers epidemiological, surgical, radiotherapy, and chemotherapy approaches. A key feature is the demonstration of the impact of cutting-edge technical knowledge on treatment; for example, interventional radiology techniques, novel surgical approaches, and image-guided radiation therapy are all extensively discussed. Diagnosis is also considered in detail, with coverage of novel serum biomarkers, pathologic staging, molecular profiling, and the full range of current and emerging imaging strategies. Further chapters are devoted to epidemiology, the role of growth factor pathways and signal transduction, and histopathology and molecular pathogenesis. Experienced practitioners in a range of specialties will find this amply illustrated book to be an invaluable source of information on the newest diagnostic and treatment techniques in biliary tract and gallbladder cancer, yet it is also sufficiently concise to offer an introduction to the field for students and community practitioners.

This is the second edition of a very well received book devoted specifically to the treatment of liver tumors by radioembolization with 90Y microspheres. The success of the first edition was based on the provision of all the fundamental information required for successful use of this therapeutic modality in clinical practice. The new edition has been fully updated to cover the most recent advances and includes additional chapters on regulations and emerging trends. Detailed information is provided on the full range of relevant topics, including hepatic vascular anatomy (including variants), dosimetry, assessment of tumor response, and the results achieved using radioembolization alone and in combination with other treatments in patients with primary or metastatic disease. Complications and side-effects are also fully discussed. This book will prove immensely valuable for both beginners and practitioners.

Bleeding from the liver surface during hepatic transection is one of the main factors affecting mortality and morbidity of liver resection. For this reason, numerous devices have been developed that employ a variety of techniques to minimize parenchymal damage and so improve the safety of resection. This book describes all the devices that are currently available for hepatic transection via open, laparoscopic, and robotic approaches. Procedures are explained and illustrated step by step using informative color figures and photographs. This landmark reference in the field will be an ideal guide for liver surgeons as well as a valuable tool for students, residents, and general surgeons.

Highly illustrated and conveniently templated for quick reference, Atlas of Liver Pathology, 4th Edition, is a useful Atlas and text for every practicing pathologist or trainee who assesses liver biopsy specimens. From cover to cover, it contains all the information needed to identify histologic features and correlate them with clinical findings, offering a clearer understanding of the clinical implications of the disease as it relates to treatment. More than 1,200 high-quality, full-color images and illustrations provide you with a complete visual guide to the vast majority of liver diseases and assist in the diagnoses of biopsy and resected liver specimens. Provides clear, templated information for each disease: Major Morphologic Features; Special Stains; Differential Diagnoses; Clinical and Biologic Behavior; and Treatment and Prognosis.  Incorporates relevant data from ancillary techniques (immunohistochemistry, cytology, cytogenetics and molecular genetics), giving you the necessary tools required to master the latest breakthroughs in diagnostic technology.  Incorporates the latest diagnostic biomarkers and their utility in differential diagnoses, newly described variants, and new histologic entities.  Contains two new chapters on liver biopsy interpretation and autoimmune hepatitis.  Features concise, bulleted text and abundant tables that cover common as well as rare diseases, differential diagnoses, and more.  An eBook version is included with purchase. The eBook allows you to access all of the text, tables, figures and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud.