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Hepatitis C Virus: The Next Epidemic, An issue of Gastroenterology Clinics of North America, Volume 44-4 (Hardcover)
Loot Price: R1,742
Discovery Miles 17 420
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Hepatitis C Virus: The Next Epidemic, An issue of Gastroenterology Clinics of North America, Volume 44-4 (Hardcover)
Series: The Clinics: Internal Medicine
Expected to ship within 12 - 17 working days
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There are over 180 million people with chronic HCV infection
worldwide with between 2.7 and 3.9 million in the United States.
Hepatitis C most significantly affects Asia and Africa, with rates
up to 15% in countries such as Egypt and up to 30% in certain
regions such as Punjab, Pakistan. Hepatitis C places a significant
burden on the public health infrastructure, as it remains the
leading cause of chronic liver disease, accounting for 50-75% of
primary liver cancers and is responsible for 30% of all liver
transplantations. It is estimated to have cost the United States
$5.5 billion in 1997, comparable to the national cost of asthma,
$5.8 billion in 1994.This number is only expected to grow as the
current HCV population ages, increasing overall rates of
compensated cirrhosis/end-stage liver disease. The evolution of
directly acting anti-virals has ushered in a new era for chronic
hepatitis C. Ongoing drug development strategy has involved
targeting several replication steps of the virus and the hope is to
see all oral therapies by late 2014 or early 2015. Thus we are at
an exciting cross roads with regard to new information and
challenges with HCV: rising disease burden with associated high
costs, the challenges globally and in multiple patient populations,
and the impending availability of effective and well tolerated
treatments. Therefore there is a need to commission an exclusive
issue of GCNA for HCV.
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