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Books > Medicine > Pre-clinical medicine: basic sciences > Physiology > Metabolism
Das Buch hebt auch in der 2. komplett uberarbeiteten und aktualisierten Auflage den interdisziplinaren Charakter der Behandlung des diabetischen Fusssyndroms hervor. Nur in einem ausgewogenen Zusammenspiel von operativ und nicht-operativ tatigen AErzten sowie den entsprechenden medizinischen Assistenzberufen ist eine umfassende und die Extremitat erhaltende Therapie moeglich. Die Umsetzung des Gelesenen in die Praxis erleichtern die therapeutischen Algorithmen und die vielen Handlungsempfehlungen, die die Autoren geben. Zahlreiche Abbildungen/Bildserien veranschaulichen daruber hinaus die Inhalte.
Dieser Ratgeber zum Abnehmen ist anders: Keine Diatvorschriften, dafur sind Genuss und Erfolg garantiert. Packen Sie Ihr Projekt Gewichtsabnahme an und lassen Sie sich von der erfahrenen Autorin und AErztin unterstutzen und informieren: - Medizinisches Fachwissen zur persoenlichen Gewichtsklasse, zum Kalorienbedarf und den gesundheitlichen Folgen von UEbergewicht. - Motivieren Sie sich mit einem Erfolgstagebuch- Essen Sie "anders", trinken Sie sich schlank, entscharfen Sie Kalorienbomben, entrumpeln Sie Ihre KuchePlus: Kosmetische Tipps, damit die Haut nicht schlaff hangt, wo vorher Fettpolster waren. Fur alle, die abnehmen wollen oder mussen: Ob Sie ein paar Kilos zu viel haben oder sich bei Ihnen starkes UEbergewicht angesammelt hat und Abnehmen dringend noetig ist. Die erfahrene Autorin und AErztin unterstutzt Sie mit Tipps und Tricks. So werden und bleiben Sie dauerhaft schlank, gesund und zufrieden mit Ihrem Koerper.
This issue of Endocrinology and Metabolism Clinics, edited by Dr. Guillermo E. Umpierrez, will focus on Cardiovascular Outcomes of Treatments available for Patients with Type 1 and 2 Diabetes. Topics include--but are not limited to--Diabetes and CAD and PVD; Prediabetes and CVD- DM prevention; Pathogenesis of atherosclerosis/CVD in diabetes Intensive Diabetes Treatment and CV Outcomes in T1D; Intensive blood glucose control and vascular outcomes in patients with type 2 diabetes, Diabetes and Stroke; Cardiovascular outcome trials of glucose-lowering drugs or strategies in type 2 diabetes; Heart Failure in Diabetes Mellitus; Individualizing Glucose Lowering Therapy in the Patient with Diabetes and Heart Disease; Managing Dyslipidemia in Type 2 Diabetes; Blood pressure control and cardiovascular and renal outcomes; Hyperglycemia in acute coronary syndromes; Hospital Glucose Control; Managing Diabetes and cardiovascular risk in chronic kidney disease; and more.
The Do's and Don'ts of Hypoglycemia: An Everyday Guide to Low Blood Sugar is a success because of its simplicity and easy-to-understand format. Its author, Roberta Ruggiero, is able to bring the do's and don'ts of treating and controlling hypoglycemia symptoms through simple diet and lifestyle changes. She takes the reader from understanding and recognizing hypoglycemia to the role diet, exercise and vitamin therapy play in the healing process. Roberta then shows the effects hypoglycemia has on our children, the correlation between hypoglycemia and alcoholism, an extensive chapter on Ask the Experts and the newly released results of a Hypoglycemia Questionnaire.
This issue of Endocrinology and Metabolism Clinics, guest edited by Drs. J. Chris Gallagher and Daniel Bikle, is devoted to Vitamin D. Articles in this issue include: The Molecular and Cellular Mechanisms of Action of Vitamin D, Worldwide Review of Serum 25OHD Status; RDA Update (7 Years Post IOM); The Use of Vitamin D Metabolites and Analogs in the Treatment of Chronic Kidney Disease; Effect of Vitamin D on Falls and Physical Performance; Vitamin D Effect on BMD and Fractures; Bariatric Surgery and Vitamin D Metabolism, Role of Vitamin D in the Prevention and Treatment of Cancer; Role of Vitamin D in Cardiovascular Disease; Regulation of Immune Function by Vitamin D and its Use in Diseases of Immunity; Genetic Diseases of Vitamin D Metabolizing Enzymes; Measurement of Vitamin D Metabolites: Clinical Issues; The Free 25OHD Hypothesis, and Ethnic/Racial Differences in Vitamin D Levels: Physiologic or Pathologic.
Ob Schwangerschaft, Wechseljahre, Verliebtsein oder Pubertat: Oft heisst es, die Hormone spielen verruckt. Doch weit gefehlt: Hormone, die Boten unseres Koerpers, beeinflussen unser Leben von der ersten Sekunde an. Nur wenn sie tun, was sie tun sollen, funktioniert unser Koerper, wie er soll. Zu wissen, wie das menschliche Hormonsystem arbeitet, ist nicht nur spannend, sondern hilft auch dabei, den eigenen Koerper und die eigenen Gefuhle und Handlungsweisen besser zu verstehen. Dieses Buch bietet gut verstandliches Fachwissen, ausfuhrlich erklart und kompakt zusammengefasst. Es liefert Informationen zu hormonellen Stoerungen und beantwortet Fragen, die sich viele von uns schon einmal gestellt haben: Warum bin ich zu dick? Warum bin ich zu dunn? Warum fallen mir hier die Haare aus und habe ich dort zu viele? Warum schwitze ich so viel? Warum bleibt meine Periode aus? Warum bin ich dauernd mude? Sind's vielleicht die Hormone? Ganz nebenbei erfahrt man auch, warum unser Hormonsystem aus der Steinzeit stammt und wieso das heute ein Problem sein kann, was Goliath mit einer Hormonstoerung zu tun hatte oder warum "Mann" nicht immer kann. Prof. Harald J. Schneider ist Facharzt fur Endokrinologie. Seit 2000 behandelt er tagtaglich Patienten, die mit diesen und vielen anderen Fragen in seine Praxis kommen. Nicola Jacobi ist ausgebildete Journalistin und freie Autorin fur verschiedene Medien. Sie ist aber auch Betroffene und beschaftigt sich deswegen seit vielen Jahren mit diesem Thema.
Trends indicate that the metabolic syndrome will become the leading risk factor for heart disease. Now more than ever you need an all-in-one reference that provides the tools and practical advice you need to: *Identify at-risk patients *Explain individual contributing factors *Aid in patient education and motivation *Direct comprehensive care and *Choose the most appropriate interventions Comprehensively revised to reflect leading-edge research and now organized to facilitate easy access to essential information and clinically-relevant guidance, Metabolic Syndrome and Cardiovascular Disease, 2e offers this and more. Not only will you receive a solid understanding of the pathophysiology underlying the metabolic syndrome and cardiovascular disease but also the rationale for today s most effective treatments. What s new? Filled with timely new content, this updated edition covers: * New discoveries that have changed our understanding of the pathogenesis and interrelationship of metabolic syndrome, cardiovascular disease (CHD), and type 2 diabetes mellitus (DM) * The relevance of mitochondria and telomeres * Sleep and its impact on cardiometabolic health * The pivotal interplay between insulin and forkhead transcriptionfactors * Calorie restriction research * Bariatric surgery experiences and outcomes In addition, each chapter includes essential information on comorbidities, interventions, and pharmacotherapeutic options an exclusive feature found only in the second edition!
Textbook of Nephro-Endocrinology, Second Edition, continues to be the definitive translational reference in the field of nephro-endocrinology, investigating both the endocrine functions of the kidneys and how the kidney acts as a target for hormones from other organ systems. It offers researchers and clinicians expert analyses of nephro-endocrine research and translation into the treatment of diseases such as anemia, chronic kidney disease (CKD), rickets, osteoporosis, and hypoparathyroidism. Changes to this edition include new chapters focused on hypercalcemia/hypocalcemia and the interaction of dialysis, chronic renal disease, and endocrine diseases. All chapters have been updated to include more preclinical data and more tables and schema that help translate this data into clinical recommendations. The section on hormones and renal insufficiency discusses insulin/diabetes, growth hormone, sex steroids, thyroid hormone, acid-base disturbances, and pregnancy.
This issue of Endocrinology and Metabolism Clinics, guest edited by Drs. Caroline M. Apovian and Nawfal Istfan, is devoted to Obesity. Articles in this comprehensive issue include: Guidelines for Obesity Management; Obesity is a Disease; Pharmacotherapy for Obesity; Bariatric Surgery Mechanisms; Diabetes Treatment in the Patient with Obesity; Adipose Tissue: Inflammation and the Endocrine Organ; Behavioral Treatment of the Patient with Obesity; The Role of Macronutrient Content in the Diet for Weight Loss and Weight Maintenance; Substrate Oxidation and Brown Adipose Tissue; Brown and Beige Adipose Tissue: Therapy for Obesity?; Ethnic Differences in Diabetes Lipids HTN and Obesity; Genetics of Bariatric Surgery Outcomes; Leptin and Hormones: Energy Homeostatis; Bariatric Surgery Clinical Outcomes; Medical Devices for Obesity; Adolescent Bariatric Surgery; Psychological Aspects of Obesity; and Nutrient Timing.
This book sheds new light on the management of patients with borderline cardiovascular risk factors in order to prevent their progression to end organ damage. The book stimulates discussion of this poorly understood condition and lays the groundwork for developing recommendations and guidelines. While the diagnostic and therapeutic approach to full-blown diabetes, hypertension, dyslipidemia and obesity is well defined, there is still a lack of clear understanding and guidelines as far as patients with borderline conditions - especially when multiple - are concerned. Moreover, end-organ damage depends on several factors, including genetic factors, making it difficult to predict its extent. As such, the gradual transition from a healthy subject to one with functional hemodynamic changes, and then one with structurally asymptomatic changes and lastly to overt disease needs further investigation. In order to address these knowledge gaps, the book covers a broad variety of topics, making it a valuable tool for identifying which asymptomatic subjects could profit from being appropriately screened and at what stage. Furthermore it offers insights into better treating these patients to prevent their progression to overt disease. The book appeals to cardiologists, primary care physicians and all those healthcare professional looking to optimize the management of these complex and often undiagnosed cases.
This issue of Endocrinology and Metabolism Clinics, edited by Dr. Alice Levine, is devoted to Adrenal Disease. This issue will be broken down into 3 sections: Overview of Adrenal Cortical Development, Steroidogenesis, Comparative Anatomy and Molecular Pathophysiology; Benign Adrenal Tumors; and Adrenal Cortical Carcinoma. Articles in this issue include: Adrenal Cortical Zonal Development; Adrenal Steroidogenesis and Congenital Adrenal Hyperplasia; Animal Models of Adrenocortical Tumorigenesis; Genetics of Adrenal Cortical Tumors; Adrenal Incidentalomas; Aldosteronomas - Challenges in Diagnosis and Management; Mild Hypercortisolism Due to Adrenal Adenomas - Definitions and Therapeutic Options; Management of Adrenal Tumors in Pregnancy; Pathology of ACC; Diagnosis and Medical Management of ACC; and Surgical Management of ACC.
Diabetes: Oxidative Stress and Dietary Antioxidants, Second Edition, builds on the success of the first edition, covering updated research on the science of oxidative stress in diabetes and the potentially therapeutic usage of natural antioxidants in the diet and food matrix. The processes within the science of oxidative stress are not described in isolation, but rather in concert with other processes, such as apoptosis, cell signaling and receptor mediated responses. This approach recognizes that diseases are often multifactorial and oxidative stress is a single component of this. Since the publication of the first edition, the science of oxidative stress and free radical biology continues to rapidly advance with thousands of the research articles on the topic. New sections in this update cover the role of dietary advanced glycation end products (AGEs) in causing OS in diabetes, oxidative stress and diabetes-induced bone metabolism, and oxidative stress and diabetic foot ulcer.
This textbook offers a concise, yet comprehensive account of human nutrition, food and nutrition-related health problems, based on the curricula of top universities around the globe. Nutrition is a multidisciplinary science, and as such, the book discusses various aspects of physiology, biochemistry, pathology, immunology, medicine, food science, and other fields related to nutrition, it focuses on the role of nutrition in the maintenance of health. The various chapters explore highly relevant issues, such as, addiction-related health problems, lifestyle-related disorders, social health problems and poor-maintenance of food hygiene and food safety. It also addresses the role of nutritional therapies for mental disorders, and includes an integrated perspective on cognition, oxidative stress and nutritional interventions in aging. Other topics include, the role of gut microbiota on human health, nutraceuticals as therapeutic agents and ketogenic diets. It also highlights malnutrition (protein energy malnutrition, starvation, malabsorption syndrome, eating disorders and overnutrition/obesity) and adipose tissue as an active endocrine organ. Moreover, it examines key concepts concerning the role of vitamins in the citric acid cycle (gluconeogenesis, ketogenesis, oxidative deamination and transamination) and precursors of coenzymes, as well as calorigenic hormones, appetite-stimulating/appetite-inhibiting hormones, anabolic and catabolic hormones affecting protein metabolism, and lipogenetic/lipolytic hormones.
Iron Metabolism, Volume 110, the latest release in the Vitamins and Hormones series first published in 1943, covers the field of hormone action, vitamin action, X-ray crystal structure, physiology and enzyme mechanisms, with this release focusing on topics relating to hepcidin, bacterial infection, and iron overload, the role of heparan sulfates in hepcidin regulation, hepcidin CDNA and human gene sex hormones, growth factors and hepcidin, HFE gene polymorphisms and hereditary hemochromatosis, hepcidin and il-1beta, hepcidin-ferroportin axis, cardiomyocyte hepcidin, adipocyte iron, leptin and hepcidin, regulators of hepcidin expression, and much more.
Wer kennt es nicht - man ist mitten im Medizinstudium, hat zwar schon einiges, aber langst noch nicht alles gelernt und fuhlt sich in Sachen Diagnosestellung alles andere als sattelfest. Und dann kommt sie, die unvermeidliche Frage auf der nachsten Familienfeier: "Du, sag mal, Du studierst doch Medizin, kannst Du mir sagen, was das hier ist?" - und ehe man sich versieht, wird man mit veranderten Hautstellen, geschwollenen Mandeln und weiteren Symptomen konfrontiert, die man gar nicht unbedingt von seiner naheren Bekannt- und Verwandtschaft sehen und wissen wollte. Einerseits schlagt da stolz das Herz in der Brust, andererseits aber nur so lange, wie man mit den Symptomen auch etwas anfangen kann. Was, wenn die Frage zur schuppenden Hautstelle vor dem Semester kommt, in dem die Dermatologie dran ist? Und wenn man auch nicht aus dem eigenen Erfahrungsfundus schoepfen kann? Was, wenn man zwar dunkel ahnt, was Besenreiser sind, aber keine Antwort auf die Frage parat hat, ob man etwas dagegen machen muss? Diese Buchreihe soll auf eine leicht verstandliche Art helfen, die meisten und gangigsten Alltagszipperlein zu erklaren und zu erkennen. Welche Fragen sollten Sie anderen oder sich stellen, um auf die richtige Fahrte zu kommen und Moegliches von Unwahrscheinlichem abzugrenzen?
FIVE STARS from Doody's Star Ratings (TM) This essential guide encompasses the core principles of Manual Lymph Drainage and Complete Decongestive Therapy for a wide range of pathologies across the age continuum. Key elements from the prior edition are incorporated, such as color-coded sections for anatomy, physiology, and pathophysiology. Advances in the field are reflected in expanded chapters and efficacy meta-analyses, updates on genetics, refinements in manual compression, and new insights on fat disorders and edema. Key highlights in fourth edition More than 140 new color images, over 30 new tables, and updated ICD-10 codes Expanded discussion of lipedema and related conditions such as Dercum's and Madelung's diseases Surgical approaches such as vascularized lymph node transfer, anastomosis and bypass techniques, suction assisted protein lipectomy, and combined and staged lymphedema operations Wound care options for edema and advanced venous disease Integration of conventional therapies and techniques in collaboration with surgeons who perform specialized lymphatic procedures Tips and guidance for growing numbers of home care focused practitioners who encounter lymphedema and related edemas in patients Management of garments including fit, functionality, and patient independence Rare pediatric syndromes and adaption of CDT for children Expanded discussion of sequential intermittent pneumatic compression including contraindications and usages in lymphedema management This is a must-have resource on the diagnosis, treatment, and management of lymphedema and lymphatic insufficiency. Its unique practicality will enable educators to teach techniques and clinicians to adeptly incorporate a wide range of treatment strategies into practice.
This issue of Endocrinology Clinics brings the reader up to date on the latest information about hormones and cancer of the breast and prostate.? The first section focuses on the breast, and topics covered include the following.? The role of sex steroids and their receptors in normal breast development; estrogen carcinogenesis in breast cancer; hormonal mechanisms underlying the relationship between obesity and breast cancer; postmenopausal hormone replacement therapy and the risk of breast cancer; aromatase inhibitors, anti-estrogen and SERMS in the treatment of breast cancer; and androgens in breast cancer in men and women.? The second section is devoted to the prostate, and topics covered include the following.? Overview of prostate anatomy, histology, and pathology; the critical role of sex steroids in normal prostate development; estrogens and androgens in prostate cancer development and the rationale for hormonal chemopreventive therapies; weighing the clinical evidence regarding the timing and extent of androgen ablative therapy for prostate cancer treatment; new hormonal therapies for castration-resistant prostate cancer; and the management of the side effects of castration therapy.
The prevalence of type 2 diabetes mellitus (T2DM) has been increasing worldwide, and it is becoming a public health concern. In this book, the pathophysiological risk factors of progression from normoglycemia to prediabetes and the lifestyle modifications and pharmacological interventions for preventing or delaying the development of glucose intolerance is examined. Furthermore, the insulin signaling pathway regulates the cellular uptake of glucose and wholebody metabolic homeostasis in mammalians. This book explores the improvement of estrogen signaling in preventing the comorbidities of insulin resistance. The next chapter focuses on nutritional management during the perioperative period, focusing on glucose metabolism and insulin sensitivity. There are three major problems for nutritional management during the perioperative period. These problems are addressed and suggestions are made on how to alleviate them. Finally, Cystic Fibrosis (CF) is the most common lethal inherited disorder in Caucasians, affecting 1 in 2,500 - 2,800 live births. The last chapter examines impaired glucose tolerance in cystic fibrosis.
This book provides a comprehensive overview of the development of metabolic syndrome, the underlying mechanisms and therapeutic strategies for drug development. The authors examine the context of underlying molecular pathways and integrated physiology, then expanding the discussion to diseases associated with metabolic syndrome. The development of drug therapies for these diseases and complications is extensively covered. The book offers a comprehensive and in-depth view of energy metabolism, metabolic tissues and pathways, molecular mechanism-based drug discovery and clinical implications.
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