'A mine of treasures, a source of visions, a microcosm of human experience and suffering, the philosopher's stone: Migraine is a remarkable achievement' - Sunday Telegraph. Migraine is an age-old - the first recorded instances date back over two thousand years - and often debilitating condition, affecting a 'substantial minority' of the population across the globe. In Migraine, Oliver Sacks offers at once a medical account of its occurrence and management; an exploration of its physical, physiological, and psychological underpinnings and consequences; and a meditation on the nature and experience of health and illness.

THE RICHARD AND JUDY BOOK CLUB PICK

THE SUNDAY TIMES BESTSELLER

A BBC RADIO 4 BOOK OF THE WEEK

SELECTED AS A BOOK OF THE YEAR BY THE TIMES

SELECTED AS A SUMMER READ BY THE SUNDAY TIMES, FINANCIAL TIMES, DAILY TELEGRAPH, THE TIMES AND THE MAIL ON SUNDAY

'Revelatory' Guardian

'A miracle' Telegraph

'Remarkable' Daily Mail

'A landmark book' Financial Times

How do you build a life when all that you know is changing?

How do you conceive of love when you can no longer recognise those who mean the most to you?

A phenomenal memoir - the first of its kind - Somebody I Used to Know is both a heart-rending tribute to the woman Wendy Mitchell once was, and a brave affirmation of the woman dementia has seen her become.

Afterword by Alzheimer's Research UK. 'Shobna Gulati is the Northern heroine of a nation' - Lemn Sissay 'Lucid and probing' - Guardian 'Wonderful and emotional, a masterpiece of resilience.' - Emma Kennedy Remember Me? is a memoir about caring for a parent with dementia and the memories that resurface in the process. In her first book, Shobna Gulati sets out to reclaim her mother's past after her death, and in turn, discovers a huge amount about herself and their relationship. Remember Me? captures the powerful emotions that these memories hold to both Shobna and her mother; secrets they had collectively buried and also the concealment of her mother's condition. What ensues is a story of cultural assimilation, identity and familial shame. 'A raw, honest, moving and wry account of the complexity of a mother daughter relationship convoluted by the torment of dementia.' - Sanjeev Bhaskar 'Gulati's book not only describes the complexities of caring (we must not forget its joys, she says, alongside its difficulties) and her mother's dementia, it is also an exploration of identity.' - Guardian 'You'll find yourself not wanting to leave her trusted embrace.' - Desiree Burch 'Beautifully written. Heartfelt.' - Kate Robbins 'I laughed, I cried ... a relationship like no other.' - Ferne Mccann

What is dementia? Is it the same as Alzheimer's? What symptoms should you look out for? Where can you go to find help? What treatments are available? In this short but comprehensive introduction, Dr Simon Atkins clears away the myths, and sets out the facts about this increasingly common condition. Whether you are concerned for yourself or someone else, First Steps to living with Dementia will advise you about how it is diagnosed, conventional medical treatments and alternative remedies, the social and financial support available, and the lifestyle changes that can help prevent it.

A provocative and fascinating look at new discoveries about the brain that challenge our ethics

The rapid advance of scientific knowledge has raised ethical dilemmas that humankind has never before had to address. Questions about the moment when life technically begins and ends or about the morality of genetically designing babies are now relevant and timely. Our ever-increasing knowledge of the workings of the human brain can guide us in the formation of new moral principles in the twenty-first century. In The Ethical Brain, preeminent neuroscientist Michael S. Gazzaniga presents the emerging social and ethical issues arising out of modern-day brain science and challenges the way we look at them. Courageous and thought-provoking -- a work of enormous intelligence, insight, and importance -- this book explores the hitherto uncharted landscape where science and society intersect.

One 'alone, but not lonely' boy's triumph over adversity, motivated by his dream of becoming a professional footballer and a longing for truth and connection. Street's childhood memoir is a sensitive and honest portrayal, through a poetic autistic lens, of growing up with learning differences and epilepsy in an unconventional family during the 1950s and 60s. A unique and vivid social document of the period, highlighting much of the discrimination still faced by minority and disabled communities today.

This set includes Volumes 1-7 of 15 short atlases reimagining the classic 5 volume Atlas of Human Central Nervous System Development. A handy paperback edition completes the coverage of the first trimester of human brain development. Serial sections from specimens between 4mm and 60mm are illustrated and annotated in great detail, together with 3D reconstructions. An introduction and glossary summarize these earliest stages of human Central Nervous System development. Key Features 1) Classic anatomical atlases 2) Detailed labeling of the earliest phases of prenatal neurological development 3) Appeals to neuroanatomists, developmental biologists and clinical practitioners. 4) Persistent relevance - brain development is not going to change.

Keeping children bodies, minds and emotions on task just got easier with this new book from self-regulation expert Teresa Garland. Featuring more than 200 practical and proven interventions, strategies and adaptation for helping children gain more control over their lives. Each chapter provides rich background and theoretical material to help the reader better understand the issues our children face.

Topics include:

* Basic and advanced methods to calm a child and to preventing outbursts and melt-downs

* Interventions to help with attention problems, impulse control, distractibility and the ability to sit still

* Stories and video-modeling for autism, along with techniques to quell repetitive behaviors

* Sensory strategies for sensitivity and craving

* Behavioral and sensory approaches to picky eating

* Ways to increase organization skills using technology and apps

* Strategies for managing strong emotions as well as techniques for releasing them

Readers' Choice Awards Honorable Mention Distinguished Honorable Mention, from Byron Borger, Hearts and Minds Bookstore "No matter how old you are or how many degrees you have or don't have-when grace takes you to school, you start in kindergarten." This was the experience of Reverend Glandion Carney when he was given the life-altering news that he has Parkinson's disease. He was plunged into denial and despair. This was not supposed to be his journey. How could he face it? With poignant vulnerability, The Way of Grace describes one man's journey into a new land of God's amazing grace. Both his honesty and his resilience will inspire and inform your own times of difficulty. In each chapter we are introduced to a spiritual practice that can carry us through difficult days: acceptance, relinquishment, community, simplicity and more. And a guide at the end of each chapter carries us into a brief and refreshing experience with each of the practices. God's unmerited grace saves us, strengthens us and sanctifies us. We too can experience lives full of grace and truth, courageously searching out God's wonders every day.

'The story of a disease that plunged its victims into a prison of viscous time, and the drug that catapulted them out of it' – Guardian Hailed as a medical classic, and the subject of a major feature film as well as radio and stage plays and various TV documentaries, Awakenings by Oliver Sacks is the extraordinary account of a group of twenty patients. Rendered catatonic by the sleeping-sickness epidemic that swept the world just after the First World War, all twenty had spent forty years in hospital: motionless and speechless; aware of the world around them, but exhibiting no interest in it – until Dr Sacks administered the then-new drug, L-DOPA, which caused them, temporarily, to awake from their decades-long slumber . . .

Though millions of depressed Americans take Prozac safely and successully, many others suffer uncomfortable or even dangerous side effects. But they needn't despair: In this comprehensive guide to relieving depression without pharmaceuticals, Michael Murray, N.D., explains the disorder itself and various exacerbating factors, including tobacco, alcohol, and caffeine; lists a range of new treatments known to produce the theraputic effects of Prozac, from St. John's Wort and Ginkgo Biloba extract to exercise programs and guided imagery, as well as the pros and cons of the much-touted "miracle drug" melatonin. Filled with detailed, practical information, this is a useful resource for anyone seeking an alternative to Prozac.

The most trusted book on multiple sclerosis, updated and revised with the latest research in combating the disease

Once known as the "crippler of young adults," now more than 75 percent of MS patients will never need a wheelchair. In "Multiple Sclerosis, " Dr. Louis J. Rosner and Shelley Ross explain that there genuinely is new hope, more than ever before, both for controlling the disease today and curing it tomorrow.

Updated with the latest research and terminology, this revised edition gets to the bottom of every treatment option from the tried-and-true to today's cutting-edge and experimental therapies. Its trusted advice covers every step of living with MS, what you need to know, and what you need to ask. Dr. Louis Rosner and Shelley Ross explain what the disease is, who gets it and why, and what people with MS can do to continue living happy and healthy lives. Whether you or your loved one has just been diagnosed with MS or has lived with it for a while, "Multiple Sclerosis" gives you the information you need to live well with the disease, including:

- The diagnosis: how to understand and identify MS as early as possible

- The varying symptoms and courses of the disease: how to recognize and treat them

- The emotional struggles that come with MS: where to turn for support

- The most current medical research and therapies available to MS patients: how to know if they are right for you

For decades, this trusted handbook has helped those with MS and their families and friends to treat and understand their disease. Research brings us closer to a cure every day, but until that day comes, patients have, in this book, the very best tool for beating MS -- the facts.

A quest is never what you expect it to be.

Elizabeth Madeline Martin spends her days in a retirement home in Cape Town, watching the pigeons and squirrels on the branch of a tree outside her window. Bedridden, her memory fading, she can recall her early childhood spent in a small wood-and-iron house in Blackridge on the outskirts of Pietermaritzburg. Though she remembers the place in detail – dogs, a mango tree, a stream – she has no idea of where exactly it is. ‘My memory is full of blotches,’ she tells her daughter Julia, ‘like ink left about and knocked over.’

Julia resolves to find the Blackridge house: with her mother lonely and confused, would this, perhaps, bring some measure of closure? A journey begins that traverses family history, forgotten documents, old photographs, and the maps that stake out a country’s troubled past – maps whose boundaries nature remains determined to resist. Kind strangers, willing to assist in the search, lead to unexpected discoveries of ancestors and wars and lullabies. Folded into this quest are the tender conversations between a daughter and a mother who does not have long to live.

Taken as one, The Blackridge House is a meditation on belonging, of the stories we tell of home and family, of the precarious footprint of life.

A Brief History of Brains bridges the gap between AI and neuroscience by telling the evolutionary story of how the brain came to be. The entirety of the human brain’s 4-billion-year story can be summarised as the culmination of five evolutionary breakthroughs, starting from the very first brains, all the way to the modern human brains. Each breakthrough emerged from new sets of brain modifications, and equipped animals with a new suite of intellectual faculties. These five breakthroughs are the organising map to this book, and they make up our itinerary for our adventure back in time. Each breakthrough also has fascinating corollaries to breakthroughs in AI. Indeed, there will be plenty of such surprises along the way. For instance: the innovation that enabled AI to beat humans in the game of Go – temporal difference reinforcement learning – was an innovation discovered by our fish ancestors over 500 million years ago. The solutions to many of the current mysteries in AI – such as ‘common sense’ – can be found in the tiny brain of a mouse. Where do emotions come from? Research suggests that they may have arisen simply as a solution to navigation in ancient worm brains. Unravelling this evolutionary story will reveal the hidden features of human intelligence and with them, just how your mind came to be.

The American Society of Addiction Medicine Handbook of Addiction Medicine, Second Edition is a practical, evidence-based guide to caring for individuals with substance use disorder. Produced by the largest medical society dedicated to the improvement of addiction care, this new edition adopts non-stigmatizing language related to addiction and includes new material on LGBTQ care, vaping, and harm reduction. The second edition also carefully presents a compassionate, patient-centered approach to care. To learn more about the American Society of Addiction Medicine, and its commitment to providing the best resources for addiction clinicians, please visit http://www.asam.org.

From an award-winning endocrinology pioneer and metabolism expert comes a revolutionary, sustainable and scientific approach to help you lose weight, regain energy, clear your mind, and prevent disease.

Like our fingerprints, each of us has a unique metabolism. Your metabolism will change as you move through life, shaping your mental and physical capabilities. However, one in four of us will experience trouble with our metabolism. Dr. Noel Maclaren, an award-winning endocrinologist and Sunita Singh Maclaren, a medical anthropology expert, share their revolutionary new approach to mastering your metabolism that combines medical and behavioral insights in order to help balance your weight, boost your energy and improve your cognitive abilities.

Imagine the metabolism as a beguiling jigsaw. We all fit into one of four ‘metabolic personality’ types, based on our bodies' levels of sensitivity to insulin. Maximize Your Metabolism offers a comprehensive self-assessment quiz to uncover yours. Drawing on pioneering data from a person’s genetic legacies, appetite signals and mental resilience, this book will enable you to create a unique plan specific to your needs, and will help you achieve robust brain and body health, including:

• Enhancing your cognitive abilities by limiting grains and fruits as the brain’s ability to absorb glucose declines from your late 40’s onwards
• Optimizing your weight by identifying the simple vs. complex carbohydrates that work for your metabolic type
• Overcoming insulin-related persistent fatigue and increasing your muscle’s energy efficiency through resistance and aerobic exercise
• Protecting yourself from disease-causing internal inflammation by opting for prebiotics found in artichokes, leeks and onions and avoiding certain “health” foods

Dr. Noel Maclaren and Sunita Singh Maclaren have helped thousands of patients in their clinic for over fifteen years, by reversing these metabolic imbalances. Filled with specific time-tested guidance and over 30 healthy and delicious recipes, Maximize Your Metabolism is perfect for anyone who wants to be a champion of their own health, gain an overall sense of wellbeing in as little as six months, and to sustain it for a lifetime.

Award winning, quirky cli-fi fantasy adventure for readers 10 years and up. If Nema can't uncover a lost boy's true identity in time they may never escape the sticky world he designed... When Nema and her friends discover a hidden sugar-hooked society holding lost kids, they find their perfect world in danger. The strange, sticky place hides the truth about Nema's missing brother, and a plot to destroy the free life she knows. But only they can reverse a code to prevent a rock candy robot invasion and rescue the captives. Fail and they might never make it back home...

A "beautiful and astonishing" (Walter Isaacson, # 1 New York Times bestselling author of The Code Breaker) narrative that examines the many ways to be fully human, told by the first young adult with autism to attend Oxford University as a Rhodes Scholar. As a child, Jory Fleming was wracked by uncontrollable tantrums, had no tolerance for people, and couldn't manage the outside world. Slightly more than a decade later, he was bound for England, selected to attend one of the world's premier universities. How to Be Human is a "profound, thought-provoking" (Barry M. Pizant, PhD, author of Uniquely Human) exploration of life amid a world constructed for neurotypical brains when yours is not. But the miracle of this book is that instead of dwelling on Jory's limitations, those who inhabit the neurotypical world will begin to better understand their own: they will contemplate what language cannot say, how linear thinking leads to dead ends, and how nefarious emotions can be, particularly when, in Jory's words, they are "weaponized." Through a series of deep, personal conversations with writer Lyric Winik, Jory makes a compelling case for logical empathy based on rational thought, asks why we tolerate friends who see us as a means to an end, and explains why he believes personality is a choice. Most movingly, he discusses how, after many hardships, he maintains a deep, abiding faith: "With people, I don't understand what goes in and what comes out, and how to relate," he says. "But I can always reconnect with my relationship with my Creator." Join Jory and Lyric as they examine what it means to be human and ultimately how each of us might become a better one. Jory asks us to consider: Who has value? What is a disability? And how do we correct the imbalances we see in the world? How to Be Human shows us the ways a beautifully different mind can express the very best of our shared humanity.