Within the last two decades endocrinological research has taken a
definite tum toward biochemistry and molecular biology. This has
resulted in a new discipline called' 'molecular endocrinology. "
Studies on the mechanism of hormone action have continued to make
headlines with fundamental discov eries in receptor action and gene
regulation. Recently the insect endocrino logists have also begun
to explore the molecular mechanism of steroid hor mone action
taking advantage of the vast number of Drosophila mutants, the
library of Drosophila gene, and several well-characterized
cell-lines. The availability ofthe recombinant DNA technology has
provided a truly revolu tionary tool in the hands of the molecular
endocrinologists. "Gene Regula tion by Steroid Hormones" is
compiled and presented in this frontier spirit, and we hope that
this volume will serve not only the active investigators in the
field but will also be very useful to students and researchers with
a gen eral interest in regulatory biology. The book is an offshoot
of the Conference on Molecular Mechanism of Steroid Hormone Action
held at the Meadow Brook Mansion of Oakland University in the fall
of 1978. We wish to acknowledge the financial assist ance from the
National Science Foundation and Oakland University. The conferees
will never forget the warmest hospitality of Dr. LOWELL EKLUND and
his staff at the Meadow Brook center and we also wish to express
per sonal gratitude to many of our students and colleagues for
helping us to make the conference a great success.
General
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