New Gold-Catalyzed Reactions and Applications for the Synthesis of Alkaloids (Paperback, Softcover reprint of the original 1st ed. 2013)

Ana Escribano Cuesta's thesis presents a detailed study of the inter- and intramolecular reactions of carbonyl compounds with 1,6-enynes using gold (I) complexes. An important part of the work involved streamlining the variables that allow the selective synthesis of different products such as tricyclic compounds, dihydropyrans, 1,3-dienes or cyclobutenes. The second chapter highlights the importance and difficulties in synthesising a cyclobutene subunit and the author includes a detailed description of how the products were prepared. The final chapter outlines the synthesis of lundurines using methodology developed by the author's research group for intramolecular gold-catalyzed cyclization of indoles with alkynes. The lundurine products developed in this work show significant in vitro cytoxicity toward B16 melanoma cells. The work in this thesis has led to a number of publications in high-profile chemistry journals.

General

Imprint:	Springer International Publishing AG
Country of origin:	Switzerland
Series:	Springer Theses
Release date:	August 2015
Authors:	Ana Escribano Cuesta
Dimensions:	235 x 155 x 11mm (L x W x T)
Format:	Paperback
Pages:	195
Edition:	Softcover reprint of the original 1st ed. 2013
ISBN-13:	978-3-319-03385-3
Categories:	Books > Science & Mathematics > Chemistry > Organic chemistry > Organometallic chemistry Books > Science & Mathematics > Chemistry > Physical chemistry > Catalysis Promotions
LSN:	3-319-03385-9
Barcode:	9783319033853

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