Food or calorie restriction has been shown in many short-lived
animals and the rhesus monkey to prolong life-span. Life-long
nutrition studies are not possible in humans because of their long
survival. Studies over two to six years in healthy adult humans
have, however, shown that a 20% reduction in food or calorie intake
slows many indices of normal and disease-related aging. Thus, it is
widely believed that long-term reduction in calorie or food intake
will delay the onset of age-related diseases such as heart disease,
diabetes and cancer, and so prolong life.
Over the last 20 or more years there has been a progressive rise
in food intake in many countries of the world, accompanied by a
rising incidence of obesity. Thus our increasing food and calorie
intake has been linked to the rising incidence of cardiovascular
disease and diabetes in early adult life. It is accepted that
overeating, accompanied by reduced physical exercise, will lead to
more age-related diseases and shortening of life-span. The answer
is to reduce our calorie intake, improve our diet, and exercise
more. But calorie restriction is extremely difficult to maintain
for long periods. How then can we solve this problem?
Edited by a team of highly distinguished academics, this book
provides the latest information on the beneficial effects of
calorie restriction on health and life-span. This book brings us
closer to an understanding at the molecular, cellular and whole
organism level of the way forward.
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