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Handbook of Safety Assessment of Nanomaterials - From Toxicological Testing to Personalized Medicine (Hardcover)
Loot Price: R5,589
Discovery Miles 55 890
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Handbook of Safety Assessment of Nanomaterials - From Toxicological Testing to Personalized Medicine (Hardcover)
Series: Jenny Stanford Series on Biomedical Nanotechnology
Expected to ship within 12 - 17 working days
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The rapidly evolving field of nanomedicine refers to the clinical
application of nanotechnologies. However, as with all new
technologies, there are ethical, safety, and regulatory issues.
This handbook, written by leading international experts, provides a
meticulous overview of the state of the art of safety assessment of
nanomaterials (nanotoxicology) in the context of their application
in nanomedicine. The volume includes a historical perspective on
the development of nanomedicine and its regulation, and a personal
view of the future of (nano)medicine by Patrick Hunziker, president
of the European Society of Nanomedicine. Ethical considerations in
relation to nanomedicine are discussed. There are a series of
chapters on organ-specific toxicities of nanomaterials, including
pulmonary and cardiovascular toxicity, neurotoxicity,
dermatotoxicity, and reproductive toxicity, as well as a discussion
on immunotoxicity and genotoxicity. The importance of a thorough
characterization of physicochemical properties of nanomaterials is
emphasized. The handbook also contains a critical discussion on the
applicability of in vitro versus in vivo methods and models for
nanosafety assessment, along with an introduction to mathematical
modeling approaches with a view to a predictive toxicology of
nanomaterials. The overall aim is to provide a comprehensive,
science-based framework for safety assessment of current and future
nanomedicines.
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