Applications of Nanotechnology in Cancer Chemotherapy offers a complete and concise summary of nanotechnological interventions for cancer management. It highlights the basics of oncology, the cancer microenvironment, targets for active drug delivery, the underlying mechanisms and molecular pathways to enhance the drug delivery to the cancer site. The book discusses the principles of basic and innovative nanocarrier-based therapeutic approaches to modulate the progression of the disease. In addition, this book also explores the evolving targeting approaches specific to the cancer site and type. The scope of the book is not limited to targeted drug delivery for various cancers, but also explores the advancements in cancer imaging and diagnostics employing the nanotechnological tools. Emphasis has been given on the important evaluation techniques like in-vitro cell culture and in-vivo animal models to assess the performance of cancer nanomedicines. The book includes clinical study reports of various drug moieties explored using variety of nanoconstructs in myriad cancer conditions with the input of global market and pharmacoeconomics.

Neurophotonics and Biomedical Spectroscopy addresses the novel state-of-the-art work in non-invasive optical spectroscopic methods that detect the onset and progression of diseases and other conditions, including pre-malignancy, cancer, Alzheimer's disease, tissue and cell response to therapeutic intervention, unintended injury and laser energy deposition. The book then highlights research in neurophotonics that investigates single and multi-photon excitation optical signatures of normal/diseased nerve tissues and in the brain, providing a better understanding of the underlying biochemical and structural changes of tissues and cells that are responsible for the observed spectroscopic signatures. Topics cover a wide array of well-established UV, visible, NIR and IR optical and spectroscopic techniques and novel approaches to diagnose tissue changes, including: label free in vivo and ex vivo fluorescence spectroscopy, Stoke shift spectroscopy, spectral imaging, Resonance Raman spectroscopy, multiphoton two Photon excitation, and more.

Electrospinning: Nanofabrication and Applications presents an overview of the electrospinning technique, nanofabrication strategies and potential applications. The book begins with an introduction to the fundamentals of electrospinning, discussing fundamental principles of the electrospinning process, controlling parameters, materials and structures. Nanofabrication strategies, including coaxial electrospinning, multi-needle electrospinning, needleless electrospinning, electro-netting, near-field electrospinning, and three-dimensional macrostructure assembling are also covered. Final sections explore the applications of electrospun nanofibers in different fields and future prospects. This is a valuable reference for engineers and materials scientist working with fibrous materials and textiles, as well as researchers in the areas of nanotechnology, electrospinning, nanofibers and textiles.

Nano-sized Multifunctional Materials: Synthesis, Properties and Applications explores how materials can be down-scaled to nanometer-size in order to tailor and control properties. These advanced, low-dimensional materials, ranging from quantum dots and nanoparticles, to ultra-thin films develop multifunctional properties. As well as demonstrating how down-scaling to nano-size can make materials multifunctional, chapters also show how this technology can be applied in electronics, medicine, energy and in the environment. This fresh approach in materials research will provide a valuable resource for materials scientists, materials engineers, chemists, physicists and bioengineers who want to learn more on the special properties of nano-sized materials.

Drug Delivery Nanosystems for Biomedical Application reviews some of the most challenging nanosystems with different routes of delivery that are useful for specific drugs, from both efficacy and bioavailability points-of-view. The chapters explore how this area is developing, the present state of the field, and future developments, in particular, inorganic, metallic, polymeric, composite and lipid nanosystems and their possible evolution to clinical applications. The book is a valuable research reference for both researchers and industrial partners who are not only interested in learning about this area, but also want to gain insights on how to move towards translational research.

Emerging Nanotechnologies in Immunology aims to deliver a systematic and comprehensive review of data concerning the nature of interaction and nano-related risks between the nanophamaceuticals currently in the pipeline of S&T development for skin, ocular, and nasal drug delivery, including absorption, toxicity, and the ability to distribute after systemic exposure. The scientific development of manufactured nanomaterials for drug delivery is increasing rapidly. One of the most prominent applications is topical drug delivery, where cutaneous, ocular, and nasal exposure becomes even more relevant. These targets are the first barrier that nanoparticles encounter when in contact with the human body. The contributors addresses a representative set of the broad spectrum of nanopharmaceuticals currently being used, including cationic lipid nanoparticles, polymeric PLGA, PLA nanoparticles, biomacromolecules-based nanoparticles, and other scaffolds tissue engineered skin substitutes. Regulation and risk is also covered, since the safety of these nanophamaceuticals still represents a barrier to their wide innovative use.

Thermohydrodynamic Programming and Constructal Design in Microsystems explains the direction of a morphing system configuration that is illustrated by life evolution in nature. This is sometimes referred to as the fourth law of thermodynamics, and was first applied in thermofluidic engineering, with more recent applications in physics and biology. The book specifically focuses on synthetic modeling and constructal optimization in the design of microsystemic devices, which are of particular interest to researchers and practitioners in the sphere of micro- and nanoscale physics, a mechanistically deviation from conventional theory. The book is an important reference resource for researchers working in the area of micro- and nanosystems technology and those who want to learn more about how thermodynamics can be effectively applied at the micro level.

Nanotechnologies and Nanomaterials for Diagnostic, Conservation and Restoration of Cultural Heritage explores how advanced nanoscale techniques can help preserve artworks. The book covers lab-scale available techniques as well as advanced methods from neutron sources and X-ray spectroscopy. Other sections highlight a variety of nanomaterials with potential uses in treatments for restoration and conservation, with conservation, consolidation and long-term protection protocols analyzed in each case. The final chapter presents case studies, demonstrates how nanoscale techniques are used to conserve art, and shows what happens when misinterpretation of data sources leads to misdiagnosis. The book is intended for scientists from academic and professional conservators, restorers who are involved in the conservation of artistic and historical artifacts, and those who want to learn how nanotechnology can increase the efficiency of conservation and protection techniques.

Experimental Characterization, Predictive Mechanical and Thermal Modeling of Nanostructures and Their Polymer Composite focuses on the recent observations and predictions regarding the size-dependent mechanical properties, material properties and processing issues of carbon nanotubes (CNTs) and other nanostructured materials. The book takes various approaches, including dedicated characterization methods, theoretical approaches and computer simulations, providing a detailed examination of the fundamental mechanisms governing the deviations of the properties of CNTs and other nanostructured materials. The book explores their applications in materials science, mechanics, engineering, chemistry and physics due to their unique and appealing properties. The use of such materials is, however, still largely limited due to the difficulty in tuning their properties and morphological and structural features.

Design of Nanostructures for Versatile Therapeutic Applications focuses on antimicrobial, antioxidant and nutraceutical applications of nanostructured materials. Many books discuss these subjects, but not from a pharmaceutical point-of-view. This book covers novel approaches related to the modulation of microbial biofilms, antimicrobial therapy and encapsulate polyphenols as antioxidants. Written by an internationally diverse group of academics, this book is an important reference resource for researchers, both in biomaterials science and the pharmaceutical industry.

Nanoparticle Technology Handbook, Third Edition, is an updated and expanded authoritative reference providing both the theory behind nanoparticles and the practical applications of nanotechnology. This third edition features twenty new chapters, providing a reference much broader in scope than the previous edition. Over 140 experts in nanotechnology and/or particle technology contributed to this new edition. The book not only includes the theory behind nanoparticles, but also the practical applications of nanotechnology. It examines future possibilities and new innovations and contains important knowledge on nanoparticle characterization and the effect of nanoparticles on the environment and humans. Nanoparticle technology is a new and revolutionary technology, which is increasingly used in electronic devices and nanomaterials. It handles the preparation, processing, application and characterization of nanoparticles and has become the core of nanotechnology as an extension of conventional fine particle/powder technology. Nanoparticle technology plays an important role in the implementation of nanotechnology in many engineering and industrial fields, including electronic devices, advanced ceramics, new batteries, engineered catalysts, functional paint and ink, drug delivery system, biotechnology, etc., making use of the unique properties of nanoparticles, which are completely different from those of bulk materials.

Microbiorobotics: Biologically Inspired Microscale Robotic Systems, Second Edition presents information on a new engineering discipline that takes a multidisciplinary approach to accomplish precise manipulation of microscale spaces. Microorganisms have evolved various mechanisms to thrive in microscale environments and are therefore a useful tool for use in many applications, ranging from micromanufacturing techniques, to cellular manipulation. In the context of microrobotics, biological microrobots can directly harness the microorganisms for propulsive and sensing power and synthetic microrobots can mimic the microorganisms' motions for effective locomotion. This second edition covers new advances and insights that have emerged in recent years. Several new chapters have been added on important new research areas, with existing chapters thoroughly revised. In particular, increased coverage is given to fluid dynamics of microswimmers in nature.

Nanoengineering: Global Approaches to Health and Safety Issues provides a global vision on the impact of engineered nanomaterials both for the consumer/general public and in occupational settings. The book also presents a hint on what can be expected for the future from nanomaterials and their effects on our lives, both at home and at work. In addition, users will find valuable information on nanomaterials' irreplaceable value and their risks for health, safety, and environmental issues. Case studies illustrate key points and provide information on important processes.

Integrated circuits, and devices fabricated using the techniques developed for integrated circuits, have steadily gotten smaller, more complex, and more powerful. The rate of shrinking is astonishing - some components are now just a few dozen atoms wide. This book attempts to answer the questions, What comes next? and How do we get there?
Nanolithography outlines the present state of the art in lithographic techniques, including optical projection in both deep and extreme ultraviolet, electron and ion beams, and imprinting. Special attention is paid to related issues, such as the resists used in lithography, the masks (or lack thereof), the metrology needed for nano-features, modeling, and the limitations caused by feature edge roughness. In addition emerging technologies are described, including the directed assembly of wafer features, nanostructures and devices, nano-photonics, and nano-fluidics.
This book is intended as a guide to the researcher new to this field, reading related journals or facing the complexities of a technical conference. Its goal is to give enough background information to enable such a researcher to understand, and appreciate, new developments in nanolithography, and to go on to make advances of his/her own.
Outlines the current state of the art in alternative nanolithography technologies in order to cope with the future reduction in size of semiconductor chips to nanoscale dimensionsCovers lithographic techniques, including optical projection, extreme ultraviolet (EUV), nanoimprint, electron beam and ion beam lithographyDescribes the emerging applications of nanolithography in nanoelectronics, nanophotonics and microfluidics"

This book provides an introduction to the physics of nanoelectronics, with a focus on the theoretical aspects of nanoscale devices. The book begins with an overview of the mathematics and quantum mechanics pertaining to nanoscale electronics, to facilitate the understanding of subsequent chapters. It goes on to encompass quantum electronics, spintronics, Hall effects, carbon and graphene electronics, and topological physics in nanoscale devices.
Theoretical methodology is developed using quantum mechanical and non-equilibrium Green s function (NEGF) techniques to calculate electronic currents and elucidate their transport properties at the atomic scale. The spin Hall effect is explained and its application to the emerging field of spintronics - where an electron s spin as well as its charge is utilised - is discussed. Topological dynamics and gauge potential are introduced with the relevant mathematics, and their application in nanoelectronic systems is explained. Graphene, one of the most promising carbon-based nanostructures for nanoelectronics, is also explored.
Begins with an overview of the mathematics and quantum mechanics pertaining to nanoscale electronicsEncompasses quantum electronics, spintronics, Hall effects, carbon and graphene electronics, and topological physics in nanoscale devicesComprehensively introduces topological dynamics and gauge potential with the relevant mathematics, and extensively discusses their application in nanoelectronic systems"

This volume in the "Methods in Enzymology" series comprehensively covers Cancer, Cardiovascular and the central nervous system of Nanomedicine. With an international board of authors, this volume is split into sections that cover subjects such as Diabetes and nanotechnology as potential therapy, Nanomedicines for inflammatory diseases, and Development and use of ceramide nanoliposomes in cancer.
Comprehensively covers cancer and the cardiovascular and central nervous systems of nanomedicineAn international board of authorsSplit into sections that cover subjects such as diabetes and nanotechnology as potential therapy, nanomedicines for inflammatory diseases, and the development and use of ceramide nanoliposomes in cancer

Coatings are used for a wide range of applications, from anti-fogging coatings for glass through to corrosion control in the aerospace and automotive industries. Nanocoatings and ultra-thin films provides an up-to-date review of the fundamentals, processes of deposition, characterisation and applications of nanocoatings.
Part one covers technologies used in the creation and analysis of thin films, including chapters on current and advanced coating technologies in industry, nanostructured thin films from amphiphilic molecules, chemical and physical vapour deposition methods and methods for analysing nanocoatings and ultra-thin films. Part two focuses on the applications of nanocoatings and ultra-thin films, with chapters covering topics such as nanocoatings for architectural glass, packaging applications, conventional and smart nanocoatings for corrosion protection in aerospace engineering and ultra-thin membranes for sensor applications.
With its distinguished editors and international team of contributors, Nanocoatings and ultra-thin films is an essential reference for professional engineers in the glazing, consctruction, electronics and transport industries, as well as all those with an academic research interest in the field.
Provides an up-to-date review of the fundamentals, processes of deposition, characterisation and applications of nanocoatingsFocuses on the applications of nanocoatings and ultra-thin films, covering topics such as nanocoatings for architectural glass, packaging applications and ultra-thin membranes for sensor applicationsIncludes chapters on current and advanced coating technologies in industry, nanostructured thin films from amphiphilic molecules, chemical and physical vapour deposition methods and methods for analysing nanocoatings and ultra-thin films

This book makes a serious effort at bringing forth and synergistically combining the concepts of green chemistry, sustainability and nanotechnology and should motivate scientistsat all levels to think clearly and seriously about creating and optimizing novel and sustainable green approaches to nanotechnology. The chapters in this book can be divided into three broad categories: 1) Advancement in research on pollution control through the green chemistry principles of nanotechnology; 2) Emergence of nanomaterials in widespread applications in various scientific fields, including but not limited to sensors and catalysts; 3) Extension of research into nanotechnology and green nanotechnology at a rapid pace. Review articles on the individual aspects of these diverse and complementary topics have become important resources for researchers, industry leaders, and regulators, both nationally and internationally. This book contains a few chapters associated with these particular themes, and provides glimpses of the many difficulties and challenges faced by those who seek to not only understand but also regulate the new nanomaterials. Nanotechnology represents a unique field of science, and necessitates new and novel sustainable approaches to create usable end products for the market place with the primary goal of yielding less adverse effects upon both human health and the environment.

This book provides an introduction to topological matter, with a focus on insulating bulk systems. A number of prerequisite concepts and tools are first laid out, including the notion of symmetry transformations, the band theory of semiconductors and aspects of electronic transport. The main part of the book discusses realistic models for both time-reversal-preserving and -violating topological insulators, as well as their characteristic responses to external perturbations. Special emphasis is given to the study of the anomalous electric, thermal and thermoelectric transport properties, the theory of orbital magnetisation, and the polar Kerr effect. The topological models studied throughout this book become unified and generalised by means of the tenfold topological-classification framework and the respective systematic construction of topological invariants. This approach is further extended to topological superconductors and topological semimetals. This book covers a wide range of topics and aims for a transparent presentation of the technical aspects involved. For this purpose, homework problems are also provided in dedicated hands-on sections. Given its structure, and the required background level of the reader, this book is particularly recommended for graduate students or researchers who are new to the field.