Design of Nanostructures for Theranostics Applications focuses on the theranostics applications of nanostructures. In particular, multifunctional nanoparticles for diagnostics and treatment of different diseases, including those relating to the blood-brain barrier, are discussed in detail. Chapters explore different type of nanostructures, covering design, fabrication, functionalization and optimization, helping readers obtain the desired properties. Written by a diverse range of international academics, this book is a valuable reference resource for those working in both nanoscience and the pharmaceutical industry.

Innovative and fusion technologies have shown an incredible ability to improve various aspects of society, such as healthcare systems. Nanobiotechnology is one such technology that is being applied to medical equipment and treatment approaches. Many pharmaceutical and medical companies have begun to count on medical nanotechnology due to its abundant applications and practical uses. Innovative Approaches for Nanobiotechnology in Healthcare Systems is a pivotal reference source that provides insights into a comprehensive collection of novel techniques used for the development of safe drugs using the available resources for diverse deadly diseases. This book discusses the various platforms of nanobiotechnology that are utilized in various fields. It is expected that bionanosytems will play a crucial role in the treatment of human diseases and the improvement of existing healthcare systems. This book is ideal for scientists, biotechnologists, microbiologists, medical professionals, entrepreneurs, policymakers, researchers, academicians, and students.

Advances in Nanomedicine for the Delivery of Therapeutic Nucleic Acids addresses several issues related to safe and effective delivery of nucleic acids (NAs) using nanoparticles. A further emphasis would be laid on the mechanism of delivery of NAs, the barriers encountered and the strategies adapted to combat them. An exhaustive account of the advantages as well shortcomings of all the delivery vectors being employed in delivery of various NAs will be provided. On final note the regulatory aspects of nanoparticles mediated NA would be discussed, with focus on their clinical relevance. The design and development of nucleic acid-based therapeutics for the treatment of diseases arising from genetic abnormalities has made significant progress over the past few years. NAs have been widely explored for the treatment of cancer and infectious diseases or to block cell proliferation and thereby caused diseases. Advances in synthetic oligonucleotide chemistry resulted in synthesis of NAs that are relatively stable in in vivo environments. However, cellular targeting and intracellular delivery of NAs still remains a challenge. Further development of NA-based therapeutics depends on the progress of safe and effective carriers for systemic administration. Nanomedicine has facilitated availability of vectors with diminished cytotoxicity and enhanced efficacy which are rapidly emerging as systems of choice. These vectors protect NAs from enzymatic degradation by forming condensed complexes along with targeted tissue and cellular delivery. During the past few years, a myriad reports have appeared reporting delivery of NAs mediated by nanoparticles. This book will provide an overview of nanoparticles being employed in the in vitro and in vivo delivery of therapeutically relevant NAs like DNA, siRNA, LNA, PNA, etc.

Advances in Semiconductor Nanostructures: Growth, Characterization, Properties and Applications focuses on the physical aspects of semiconductor nanostructures, including growth and processing of semiconductor nanostructures by molecular-beam epitaxy, ion-beam implantation/synthesis, pulsed laser action on all types of III-V, IV, and II-VI semiconductors, nanofabrication by bottom-up and top-down approaches, real-time observations using in situ UHV-REM and high-resolution TEM of atomic structure of quantum well, nanowires, quantum dots, and heterostructures and their electrical, optical, magnetic, and spin phenomena. The very comprehensive nature of the book makes it an indispensable source of information for researchers, scientists, and post-graduate students in the field of semiconductor physics, condensed matter physics, and physics of nanostructures, helping them in their daily research.

Emerging Nanotechnologies in Food Science presents the current knowledge and latest developments in food nanotechnology, taking a multidisciplinary approach to provide a broad and comprehensive understanding of the field. Food nanotechnology is a newly emergent discipline that is fast-growing and evolving. The discipline continues to benefit from advances in materials and food sciences and has enormous scientific and economic potential. The book presents nano-ingredients and engineered nanoparticles developed to produce technologically improved food from both food science and engineering perspectives. In addition, subsequent chapters offer a review of recent outstanding inventions in food nanotechnology and legal considerations for the protection of intellectual property in this area. With its multidisciplinary team of contributors, this book serves as a reference book for the ever-growing food nanotechnology science.

Adverse Effects of Engineered Nanomaterials: Exposure, Toxicology, and Impact on Human Health, Second Edition, provides a systematic evaluation of representative engineered nanomaterials (ENM) of high volume production and their high economic importance. Each class of nanomaterials discussed includes information on what scientists, industry, regulatory agencies, and the general public need to know about nanosafety. Written by leading international experts in nanotoxicology and nanomedicine, this book gives a comprehensive view of the health impact of ENM, focusing on their potential adverse effects in exposed workers, consumers, and patients. All chapters have been updated with new sections on the endocrine system and other organ systems. In addition, other newly added sections include introductory chapters on the physio-chemical characterization of nanomaterials and interactions between nanomaterials and biological systems, as well as a new chapter that explores risk assessment and management of nanomaterials. This book fills an important need in terms of bridging the gap between experimental findings and human exposure to ENM, also detailing the clinical and pathological consequences of such exposure in the human population.

Water Purification, a volume in the Nanotechnology in the Food Industry series, provides an in-depth review of the current technologies and emerging application of nanotechnology in drinking water purification, also presenting an overview of the common drinking water contaminants, such as heavy metals, organics, microorganisms, pharmaceuticals, and their occurrences in drinking water sources. As the global water crisis has motivated the industry to look for alternative water supplies, nanotechnology presents significant potential for utilizing previously unacceptable water sources. This books explores the practical methodologies for transforming water using nanotechnologies, and is a comprehensive reference to a wide audience of food science research professionals, professors, and students who are doing research in this field.

Functionalized Nanomaterials for the Management of Microbial Infection: A Strategy to Address Microbial Drug Resistance introduces the reader to the newly developing use of nanotechnology to combat microbial drug resistance. Excessive use of antibiotics and antimicrobial agents has produced an inexorable rise in antibiotic resistance in bacterial pathogens. The use of nanotechnology is currently the most promising strategy to overcome microbial drug resistance. This book shows how, due to their small size, nanoparticles can surmount existing drug resistance mechanisms, including decreased uptake and increased efflux of the drug from the microbial cell, biofilm formation, and intracellular bacteria. In particular, chapters cover the use of nanoparticles to raise intracellular antimicrobial levels, thus directly targeting sites of infection and packaging multiple antimicrobial agents onto a single nanoparticle.

Defect Structure and Properties of Nanomaterials: Second and Extended Edition covers a wide range of nanomaterials including metals, alloys, ceramics, diamond, carbon nanotubes, and their composites. This new edition is fully revised and updated, covering important advances that have taken place in recent years. Nanostructured materials exhibit unique mechanical and physical properties compared with their coarse-grained counterparts, therefore these materials are currently a major focus in materials science. The production methods of nanomaterials affect the lattice defect structure (vacancies, dislocations, disclinations, stacking faults, twins, and grain boundaries) that has a major influence on their mechanical and physical properties. In this book, the production routes of nanomaterials are described in detail, and the relationships between the processing conditions and the resultant defect structure, as well as the defect-related properties (e.g. mechanical behavior, electrical resistance, diffusion, corrosion resistance, thermal stability, hydrogen storage capability, etc.) are reviewed. In particular, new processing methods of nanomaterials are described in the chapter dealing with the manufacturing procedures of nanostructured materials. New chapters on (i) the experimental methods for the study of lattice defects, (ii) the defect structure in nanodisperse particles, and (iii) the influence of lattice defects on electrical, corrosion, and diffusion properties are included, to further enhance what has become a leading reference for engineering, physics, and materials science audiences.

Nanotechnology Applications in Food: Flavor, Stability, Nutrition, and Safety is an up-to-date, practical, applications-based reference that discusses the advantages and disadvantages of each application to help researchers, scientists, and bioengineers know what and what not to do to improve and facilitate the production of food ingredients and monitor food safety. The book offers a broad spectrum of topics trending in the food industry, such as pharmaceutical, biomedical, and antimicrobial approaches in food, highlighting current concerns regarding safety, regulations, and the restricted use of nanomaterials.

The world of nanomaterials is complex; there is dubiety as well as unrealistic optimism about costs, practicality, timing for the availability of, and the true capabilities of products featured in the news. The progress of the industry is being affected from the incertitude generated by the multitudinous names used, coupled with lack of clarity and standardization in the definitions for carbonaceous nanomaterials, such as graphene, graphene oxide, nanographene, nanographene flakes, nanographite flakes, graphene nanoribbons, single-layer graphene, few-layer graphene, nanographite, nanotubes, nanofibers. In this perspicuous book about the carbonaceous nanomaterial domain, the author concisely covers nomenclature, characteristics, applications, costs, and manufacturing; all with the cardinal goal to offer the reader a reality check by delineating the steps to commercialization. Along the way, he also examines the cost impact of the touted applications and the boundaries of market adoption. Through references and personal experience, the author makes a compelling case for the market readiness of a mostly neglected class of nanomaterials known as Graphitic Nanofibers. Includes varied levels of technical focus and financial analyses to appeal to a range of skills and interests.

Nanomaterials exhibit unique mechanical and physical properties compared to their coarse-grained counterparts, and are consequently a major focus of current scientific research. Defect structure in nanomaterials provides a detailed overview of the processing methods, defect structure and defect-related mechanical and physical properties of a wide range of nanomaterials. The book begins with a review of the production methods of nanomaterials, including severe plastic deformation, powder metallurgy and electrodeposition. The lattice defect structures formed during the synthesis of nanomaterials are characterised in detail. Special attention is paid to the lattice defects in low stacking fault energy nanomaterials and metal - carbon nanotube composites. Topics covered in the second part of the book include a discussion of the thermal stability of defect structure in nanomaterials and a study of the influence of lattice defects on mechanical and hydrogen storage properties.

This book is an overview of the strategies to generate high-quality films of one-dimensional semiconductor nanostructures on flexible substrates (e.g., plastics) and the use of them as building blocks to fabricating flexible devices (including electronics, optoelectronics, sensors, power systems). In addition to engineering aspects, the physics and chemistry behind the fabrication and device operation will also be discussed as well. Internationally recognized scientists from academia, national laboratories, and industries, who are the leading researchers in the emerging areas, are contributing exceptional chapters according to their cutting-edge research results and expertise. This book will be an on-time addition to the literature in nanoscience and engineering. It will be suitable for graduate students and researchers as a useful reference to stimulate their research interest as well as facilitate their research in nanoscience and engineering.

Progress in Rubber Nanocomposites provides an up-to-date review on the latest advances and developments in the field of rubber nanocomposites. It is intended to serve as a one-stop reference resource to showcase important research accomplishments in the area of rubber nanocomposites, with particular emphasis on the use of nanofillers. Chapters discuss major progress in the field and provide scope for further developments that will have an impact in the industrial research area. Global leaders and researchers from industry, academia, government, and private research institutions contribute valuable information.

Industrial Applications of Carbon Nanotubes covers the current applications of carbon nanotubes in various industry sectors, from the military to visual display products, and energy harvesting and storage. It also assesses the opportunities and challenges for increased commercialization and manufacturing of carbon nanotubes in the years ahead. Real-life case studies illustrate how carbon nanotubes are used in each industry sector covered, providing a valuable resource for scientists and engineers who are involved and/or interested in carbon nanotubes in both academia and industry. The book serves as a comprehensive guide to the varied uses of carbon nanotubes for specialists in many related fields, including chemistry, physics, biology, and textiles.

Supra-materials Nanoarchitectonics provides the latest information on design at the nanoscale, presenting a range of the new challenges that arise as the manipulation techniques that work at the macro- and micro-scale do not work at the nanoscale. The term nanoarchitectonics, coined by Japan's National Institute for Materials Science (NIMS), describes the organized interactions required at the nanoscale, replacing the traditional structure-building approach used in materials design. Nanoarchitectonics approaches material design via a profound understanding of the interactions between individual nanostructures and their organization. As the nanoarchitectonics paradigm fits well with the discipline of supramolecular chemistry, this book brings together these two approaches to demonstrate the potential of supramolecular nanoarchitectonics in the development of new materials, both at the nano- and macro-scale.

Nanobiosensors: Nanotechnology in the Agri-Food Industry, Volume 8, provides the latest information on the increasing demand for robust, rapid, inexpensive, and safe alternative technologies that monitor, test, and detect harmful or potentially dangerous foods. Due to their high sensitivity and selectivity, nanobiosensors have attracted attention for their use in monitoring not only biological contaminants in food, but also potential chemical and physical hazards. This book offers a broad overview regarding the current progress made in the field of nanosensors, including cutting-edge technological progress and the impact of these devices on the food industry. Special attention is given to the detection of microbial contaminants and harmful metabolotes, such as toxins and hormones, which have a great impact on both humans and animal health and feed.

Nanofiber Composite Materials for Biomedical Applications presents new developments and recent advances in nanofiber-reinforced composite materials and their use in biomedical applications, including biomaterial developments, drug delivery, tissue engineering, and regenerative medicine. Unlike more conventional titles on composite materials, this book covers the most innovative new developments in nanofiber-based composites, including polymers, ceramics, and metals, with particular emphasis on their preparation and characterization methodology. Selected case studies illustrate new developments in clinical and preclinical use, making the information critical for the development of new medical materials and systems for use in human health care, and for the exploration of new design spaces based on these nanofibers. This book is essential reading for those working in biomedical science and engineering, materials science, nanoscience, biomedical nanotechnology, and biotechnology.

The book will take a systematic look at nanoparticle risks within the paradigm of risk assessment, consider the limitations of this paradigm in dealing with the extreme uncertainties regarding many aspects of nanoparticle exposure and toxicity, and suggest new methods for assessing and managing risks in this context. It will consider the occupational environment where the potential for human exposure is the greatest as well as the issues relevant to occupational exposure assessment (e.g., the exposure metric) and the evidence from toxicological and epidemiological studies. A chapter will be devoted to how conventional risk assessment can be carried out for a candidate nanoparticle (e.g., carbon nanotubes), and the limitations that arise from this approach. We will propose several alternate methods in another chapter including screening assessments and adapting the rich methodological literature on the use of experts for risk assessment. Another chapter will deal with non-occupational populations, their susceptibilities, and life-cycle risk assessments. There will be a chapter on current risk management and regulatory oversight frameworks and their adequacy. This chapter will also include a discussion of U.S. and E.U. approaches to risk assessment, as well as corporate approaches.

The MEMS (Micro Electro-Mechanical Systems) market returned to growth in 2010. The total MEMS market is worth about $6.5 billion, up more than 11 percent from last year and nearly as high as its historic peak in 2007. MEMS devices are used across sectors as diverse as automotive, aerospace, medical, industrial process control, instrumentation and telecommunications - forming the nerve center of products including airbag crash sensors, pressure sensors, biosensors and ink jet printer heads. Part of the MEMS cluster within the Micro & Nano Technologies Series, this book covers the fabrication techniques and applications of thick film piezoelectric micro electromechanical systems (MEMS). It includes examples of applications where the piezoelectric thick films have been used, illustrating how the fabrication process relates to the properties and performance of the resulting device. Other topics include: top-down and bottom-up fabrication of thick film MEMS, integration of thick films with other materials, effect of microstructure on properties, device performance, etc.