This book presents the state-of-the-art advances and applications of nanozymes, the recently developing branch of enzymology that synthesizes and uses nanomaterials that mimic the function of traditional enzymes. During the past decade, the study of nanozymes has grown rapidly. Several new nanomaterials that exhibit enzymatic actions have been identified, along with new applications for their practical use. This book draws upon the work of experts from around the world and provides an in-depth analysis and cutting-edge overview of nanozymes, with an eye toward their present and future applications. Chapters are arranged in a logical order to provide physio-chemical characterization of nanozyme and basic mechanisms of their enzymatic actions. Focusing on current limitations of nanozymes and their reaction kinetics, the book presents a comprehensive discourse on nanozyme engineering that includes possible surface modifications to enhance nanozyme effectiveness. It also focuses on traditional and novel nanozyme applications, such as biosensing, drug delivery, and disease therapy, as well as their use as antibacterials. An important addition in this book is the summary of emerging literature on nanozyme toxicology. This book is intended as a ready reference for advanced undergraduate and graduate students doing research in nanotechnology; materials science; chemistry; and chemical, biological, biomedical, and food engineering. Research and development scientists, engineers, and technologists working in the chemical and biological/biomedical industries will gain much from the materials in this book for their industry practice. Presents a comprehensive discourse on nanozyme engineering that includes possible surface modifications to enhance nanozyme effectiveness. Discusses metal organic frameworks as nanozymes. Reviews on traditional and novel nanozyme applications, such as biosensing, drug delivery, disease therapy, and their use as antibacterials. Examines nanozyme toxicology. Dr. Sundaram Gunasekaran is a Professor in the Department of Biological Systems Engineering at the University of Wisconsin-Madison.

Nanomedicine, a scientific branch of nanotechnology that operates on the same scale as biology, offers the possibility of influencing the healing process from inside of the body by manipulating the matter at cellular or molecular levels. Throughout this book, current healing approaches based on this revolutionary new technology are summarized from a scientific assessment. The aim of the authors is to give, through select examples, a deep insight to nanotechnology status and the great progress that its rigorous application will bring to human health. The authors' commitment is to broaden the vision of health professionals who will eventually be the future users of this knowledge.

This book collects selected papers from the 17th and 18th Annual Conference of the Chinese Society of Micro/Nano Technology (CSMNT2015 and CSMNT2016).The papers cover various fields, like Micro/Nano Transducer/Robot, Microfluidic Devices and Systems, Micro/Nano Fabrication & Measurement Technologies, Microfluidics and Nano Fluids, Nano Material Research/Nanotube/Nanowire Devices, MEMS/NENS and Applications, Nanometer Biological/Nano Medicine, Packaging Technology. All the papers are written by Chinese researchers. From this book, you can have an overview of research of MEMS and nano technology in China. The reader can be researchers, graduate students, and engineers who are working in the field of MEMS and nano technology.

The book discusses in a detailed manner various nanomaterials used for biomedical applications, including clinical applications, diagnosis and tissue engineering. After the presentation of an overview of biomedical nanomaterials, including their classification and applications, the first part of the book is devoted to biomedical nanomaterials for therapy applications. For example, polymer micelles, dendrimers, polymer-drug conjugates as well as antibody-drug conjugates are discussed with respect to their cancer drug delivery properties. The next parts discuss biomedical nanomaterials that are used for imaging, diagnosis and sensors, as well as for tissue engineering. In the final section, the safety of biomedical nanomaterials is elaborated.

Conducting polymers are organic polymers which contain conjugation along the polymer backbone that conduct electricity. Conducting polymers are promising materials for energy storage applications because of their fast charge-discharge kinetics, high charge density, fast redox reaction, low-cost, ease of synthesis, tunable morphology, high power capability and excellent intrinsic conductivity compared with inorganic-based materials. Conducting Polymers-Based Energy Storage Materials surveys recent advances in conducting polymers and their composites addressing the execution of these materials as electrodes in electrochemical power sources. Key Features: Provides an overview on the conducting polymer material properties, fundamentals and their role in energy storage applications. Deliberates cutting-edge energy storage technology based on synthetic metals (conducting polymers) Covers current applications in next-generation energy storage devices. Explores the new aspects of conducting polymers with processing, tunable properties, nanostructures and engineering strategies of conducting polymers for energy storage. Presents up-to-date coverage of a large, rapidly growing and complex conducting polymer literature on all-types electrochemical power sources. This book is an invaluable guide for students, professors, scientists, and R&D industrial specialists working in the field of advanced science, nanodevices, flexible electronics, and energy science.

After the drug discovery and development process, designing suitable formulations to safely deliver the optimum dose, while avoiding side effects, has been a constant challenge, especially when drugs are very toxic and have poor solubility and undesirable clearance profiles. With recent advances in synthetic technologies, nanoparticles can be custom-made from a variety of advanced materials to mimic the bioenvironment and can be equipped with various targeting and imaging moieties for site-specific delivery and real-time imaging. Drug Delivery Using Nanomaterials covers advancements in the field of nanoparticle-based drug-delivery systems, along with all the aspects needed for a successful and marketable nanoformulation. FEATURES Offers a general overview of the entire process involved in the synthesis and characterization of pharmaceutical nanoparticles Covers a broad range of synthetic materials for developing nanoformulations customized for specific disease states, target organs, and drugs Every chapter sequentially builds, providing a progressive pathway from classical nanoparticles to the more advanced to be used as a full drug product by consumers Provides information in a bottom-up manner in that definitions and explanations of relevant background information serve as a framework for understanding advanced concepts This user-friendly reference is aimed at materials engineers, chemical engineers, biomedical engineers, pharmaceutical scientists, chemists, and others working on advanced drug delivery, from academia as well as industry.

Explores how antiviral nanomaterials can be used in developing targeted drug delivery practices and enable pharmaceutical industries to reformulate available drugs on market Covers immunization, imaging, and drug delivery and features various case studies on managing viral diseases Addresses synthesis protocols and recent developments by performing physicochemistry on virion substrate, hybrid viral networks, and multilayered arrays thus enabling R&D experts to study and successfully instigate cutting-edge technologies unique to viruses Discusses current and near future applications of antiviral nanomaterials and their activity in drug delivery systems Describes the role of nanotechnology in prevention, detection, and treatment of COVID-19 Investigates the role of antiviral nanodrugs play in human and animal body systems and in major viral disease types.

This book describes in a comprehensive manner latest studies conducted by various research groups worldwide focusing on carbon and related nanomaterials. Fourteen chapters of this book deal with a number of key research topics and applications of pure and functionalized carbon nanomaterials and their hybrid nanocomposites. Specifically, the authors have presented interdisciplinary investigations including: (i) carbon nanoparticles and layers synthesis, (ii) analytical aspects of carbon nanomaterials and their characterisation under different conditions as well as (iii) various applications of carbon nanoparticles. They have reported and summarised key applications of carbon particles or nanoobjects in pharmacy, biomedicine, agriculture and food industry, water treatment, physicochemical analysis, optoelectronics, electronic and magnetic materials for supercapacitors or radar adsorbing materials, tribology, chromatography, electrophoresis, bioanalysis, nanobiocatalysis, biofuels production as well as environmental remediation.

This book presents an overview of the current status of translating the RNAi cancer therapeutics in the clinic, a brief description of the biological barriers in drug delivery, and the roles of imaging in aspects of administration route, systemic circulation, and cellular barriers for the clinical translation of RNAi cancer therapeutics, and with partial content for discussing the safety concerns. It then focuses on imaging-guided delivery of RNAi therapeutics in preclinical development, including the basic principles of different imaging modalities, and their advantages and limitations for biological imaging. With growing number of RNAi therapeutics entering the clinic, various imaging methods will play an important role in facilitating the translation of RNAi cancer therapeutics from bench to bedside. RNAi technique has become a powerful tool for basic research to selectively knock down gene expression in vitro and in vivo. Our scientific and industrial communities have started to develop RNAi therapeutics as the next class of drugs for treating a variety of genetic disorders, such as cancer and other diseases that are particularly hard to address with current treatment strategies. Key Features Provides insight into the current advances and hurdles of RNAi therapeutics. Accelerates RNAi, miRNAs, and siRNA drug development for cancer therapy from bench to bedside. Addresses various modifications and novel delivery strategies for miRNAs, piRNAs and siRNA delivery in anticancer therapeutics. Explores the need for the interaction of hematologists,cell biologists, immunologists, and material scientists in the development of novel cancer therapies. Describes the current status of clinical trials related to miRNA and siRNA-based cancer therapy Presents remaining issues that need to be overcome to establish successful therapies.

Covers hydrothermal properties of a wide range of polymer composites Explains possible superior advantages and limitations of nano FRP composites in various simple and super critical applications Describes materials containing both nanoparticles and fibers and provides a different perspective than competitive titles

Black phosphorus (BP)-based two-dimensional (2D) nanomaterials are used as components in practical industrial applications in biomedicine, electronics, and photonics. There is a need to controllably shape engineered scalable structures of 2D BP building blocks, and their assembly/organization is desired for the formation of three-dimensional (3D) forms such as macro and hybrid architectures, as it is expected that these architectures will deliver even better materials performance in applications. Semiconducting Black Phosphorus: From 2D Nanomaterial to Emerging 3D Architecture provides an overview of the various synthetic strategies for 2D BP single-layer nanomaterials, their scalable synthesis, properties, and assemblies into 3D architecture. The book covers defect engineering and physical properties of black phosphorous; describes different strategies for the development of 2D nanostructures of BP with other species such as polymers, organic molecules, and other inorganic materials; offers a comparative study of 3D BP structures with other 3D architectures such as dichalcogenides (TMDs, graphene, and boron nitride); and discusses in detail applications of 3D macrostructures of BP in various fields such as energy, biomedical, and catalysis. This is an essential reference for researchers and advanced students in materials science and chemical, optoelectronic, and electrical engineering.

The cornerstone and principal feature of this book includes the urgency and necessity priority and nanometer scale (where size is measured in one billionth of a meter) are in possession of nanoscale practical application delivery, convergence and the transformation of both the North American Industry Classification System (NAICS), 2012, and the United Nations International Standard Industrial Classification of All Economic Activities, Rev.4, into sources of global competitive advantage worldwide economic growth. The challenge that has blocked this global nanotechnology priority strategy is the 2007-2008 to 2012-2013 financial, economic, monetary, banking and corporations crisis and collapse. Leading factors in the creation of this financial and economic crisis include the huge global over-the-counter (OTC) derivatives accumulation in excess of the demand for dollars. This challenge was orchestrated by mega aggregate concentration that consisted of voting rights in major corporations, structure of corporate concentration, institutional shareholders, and interlocking directorates. There were catastrophic and calamity consequences accompanied by U.S. Federal Reserve Asset Purchases.

Nanoscale electrochemistry has revolutionized electrochemical research and technologies and has made broad impacts in other fields, including nanotechnology and nanoscience, biology, and materials chemistry. Nanoelectrochemistry examines well-established concepts and principles and provides an updated overview of the field and its applications. This book covers three integral aspects of nanoelectrochemistry. The first two chapters contain theoretical background, which is essential for everyone working in the field-specifically, theories of electron transfer, transport, and double-layer processes at nanoscale electrochemical interfaces. The next chapters are dedicated to the electrochemical studies of nanomaterials and nanosystems, as well as the development and applications of nanoelectrochemical techniques. Each chapter is self-contained and can be read independently to provide readers with a compact, up-to-date critical review of the subfield of interest. At the same time, the presented collection of chapters serves as a serious introduction to nanoelectrochemistry for graduate students or scientists who wish to enter this emerging field. The applications discussed range from studies of biological systems to nanoparticles and from electrocatalysis to molecular electronics, nanopores, and membranes. The book demonstrates how electrochemistry has contributed to the advancement of nanotechnology and nanoscience. It also explores how electrochemistry has transformed itself by leading to the discovery of new phenomena, enabling unprecedented electrochemical measurements and creating novel electrochemical systems.

Among electrode materials, inorganic materials have received vast consideration owing to their redox chemistry, chemical stability, high electrochemical performance, and high-power applications. These exceptional properties enable inorganic-based materials to find application in high-performance energy conversion and storage. The current advances in nanotechnology have uncovered novel inorganic materials by various strategies and their different morphological features may serve as a rule for future supercapacitor electrode design for efficient supercapacitor performance. Inorganic Nanomaterials for Supercapacitor Design depicts the latest advances in inorganic nanomaterials for supercapacitor energy storage devices. Key Features: ? Provides an overview on the supercapacitor application of inorganic-based materials. ? Describes the fundamental aspects, key factors, advantages, and challenges of inorganic supercapacitors. ? Presents up-to-date coverage of the large, rapidly growing, and complex literature on inorganic supercapacitors. ? Surveys current applications in supercapacitor energy storage. ? Explores the new aspects of inorganic materials and next-generation supercapacitor systems.

With this handbook, the distinguished team of editors has combined the expertise of leading nanomaterials scientists to provide the latest overview of this field. They cover the whole spectrum of nanomaterials, ranging from theory, synthesis, properties, characterization to application, including such new developments as quantum dots, nanoparticles, nanoporous materials, nanowires, nanotubes, and nanostructured polymers.
The result is recommended reading for everybody working in nanoscience: Newcomers to the field can acquaint themselves with this exciting subject, while specialists will find answers to all their questions as well as helpful suggestions for further research.

Nanoelectronic Devices for Hardware and Software Security has comprehensive coverage of the principles, basic concepts, structure, modeling, practices, and circuit applications of nanoelectronics in hardware/software security. It also covers the future research directions in this domain. In this evolving era, nanotechnology is converting semiconductor devices dimensions from micron technology to nanotechnology. Nanoelectronics would be the key enabler for innovation in nanoscale devices, circuits, and systems. The motive for this research book is to provide relevant theoretical frameworks that include device physics, modeling, circuit design, and the latest developments in experimental fabrication in the field of nanotechnology for hardware/software security. There are numerous challenges in the development of models for nanoscale devices (e.g., FinFET, gate-all-around devices, TFET, etc.), short channel effects, fringing effects, high leakage current, and power dissipation, among others. This book will help to identify areas where there are challenges and apply nanodevice and circuit techniques to address hardware/software security issues.

Recent years have seen fast development in the field of self-cleaning coatings towards varied applications, such as solar cells, flat display panels, smart cellular phones, building windows, oil pipelines, vehicle coatings and optical devices. The field has been rapidly gaining attention, not only from research and teaching scientists, but also from a growing population of college and graduate students. Self-cleaning coatings describes this interesting field, providing details of natural counterparts with self-cleaning functions, theoretical aspects of self-cleaning phenomena, fabrication strategies and methods, applications and industrial impacts. Edited and written by world-renowned scientists in the field, this book will provide an excellent overview of this field and will be of interest to materials and polymer scientists working in industry and academia.

Explains the influence of InAs material in the performance of HEMTs and MOS-HEMTs Covers novel indium arsenide architectures for achieving terahertz frequencies Discusses impact of device parameters on frequency response Illustrates noise characterization of optimized indium arsenide HEMTs Introduces terahertz electronics including sources for terahertz applications

Diffractive Nanophotonics demonstrates the utility of the well-established methods of diffractive computer optics in solving nanophotonics tasks. It is concerned with peculiar properties of laser light diffraction by microoptics elements with nanoscale features and light confinement in subwavelength space regions. Written by recognized experts in this field, the book covers in detail a wide variety of advanced methods for the rigorous simulation of light diffraction. The authors apply their expertise to addressing cutting-edge problems in nanophotonics. Chapters consider the basic equations of diffractive nanophotonics and related transformations and numerical methods for solving diffraction problems under strict electromagnetic theory. They examine the diffraction of light on two-dimensional microscopic objects of arbitrary shape and present a numerical method for solving the problem of diffraction on periodic diffractive micro- and nanostructures. This method is used in modern trends in nanophotonics, such as plasmonics, metamaterials, and nanometrology. The book describes the simulation of electromagnetic waves in nanophotonic devices and discusses two methods of calculating the spatial modes of microstructured photonic crystal fibres-a relatively new class of optical fibres with the properties of photonic crystals. The book explains the theory of paraxial and non-paraxial laser beams with axial symmetry and an orbital angular momentum-called vortex beams-which are used for optical trapping and rotating micro- and nanoparticles in a ring in the cross-sectional plane of the beam. The final chapter discusses methods for calculating the force and torque exerted by the electromagnetic field focused onto the microparticle of arbitrary form, whose dimensions are comparable with the wavelength of light.

This book presents a systematic treatise on micromechanics and nanomechanics, which encompasses many important research and development areas such as composite materials and homogenizations, mechanics of quantum dots, multiscale analysis and mechanics, defect mechanics of solids including fracture and dislocation mechanics, etc.In this second edition, some previous chapters are revised, and some new chapters added - crystal plasticity, multiscale crystal defect dynamics, quantum force and stress, micromechanics of metamaterials, and micromorphic theory.The book serves primarily as a graduate textbook and intended as a reference book for the next generation of scientists and engineers. It also has a unique pedagogical style that is specially suitable for self-study and self-learning for many researchers and professionals who do not have time attending classes and lectures.

'The author has made this book accessible to many readers interested in learning about the fascinating world of nanotechnology by limiting the necessary background for understanding the book ... The book takes a very complex subject and makes very clear explanations, with many illustrations, that will give the reader an opportunity to understand these, oftentimes, counterintuitive concepts. Understanding these concepts allows one to more fully appreciate the sophistication of many of todayaEURO (TM)s electronic devices.'IEEE Electrical Insulation MagazineEveryone is familiar with the amazing performance of a modern smartphone, powered by a billion-plus nanotransistors, each having an active region that is barely a few hundred atoms long. The same amazing technology has also led to a deeper understanding of the nature of current flow and heat dissipation on an atomic scale which is of broad relevance to the general problems of non-equilibrium statistical mechanics that pervade many different fields.This book is based on a set of two online courses originally offered in 2012 on nanoHUB-U and more recently in 2015 on edX. In preparing the second edition the author decided to split it into parts A and B titled Basic Concepts and Quantum Transport respectively, along the lines of the two courses. A list of available video lectures corresponding to different sections of this volume is provided upfront.To make these lectures accessible to anyone in any branch of science or engineering, the author assume very little background beyond linear algebra and differential equations. However, the author will be discussing advanced concepts that should be of interest even to specialists, who are encouraged to look at his earlier books for additional technical details.

Systems displaying competing interactions of some kind are widespread - much more, in fact, as commonly anticipated (magnetic and Ising-type interactions or the dynamics of DNA molecules being only two popular examples).

Written for researchers in the field with different professional backgrounds, this volume classifies phenomena not by system but rather by the type of competing interactions involved. This allows for a straightforward presentation of the underlying principles and the universal laws governing the behaviour of different systems.

Starting with a historical overview, the author proceeds by describing self-competitions of various types of interactions (such as diploar or multipolar interactions), competitions between a short-range and a long-range interaction (as in Ising systems or DNA models) or between a long-range interaction and an anisotropy (as in ultrathin magnetic films or magnetic nanoparticles) and finally competitions between interactions of the same range (as in spin glasses).

Each chapter contains a few problems with solutions which provide suitable material for lecturers of mathematics and physics as well as biology courses.
A vast body of references to the original literature make the volume self-contained and ideally suited to master this interdisciplinary field.

Drying processes are among the most energy-consuming operations in industry. Flame spray drying (FSD) is a novel approach to reduce the energy supply needed for the spray drying process. Flame Spray Drying: Equipment, Mechanism, and Perspectives describes FSD technology and current developments in flame techniques and evaluates potential industrial implementation. Details advantages of FSD in terms of energy consumption and reduced drying time Promotes applications of biofuels for the drying process Analyzes the FSD method from CFD modelling to product quality Evaluates potential safety and product degradation risks Provides examples of potential applications of the FSD technique in drying of different materials This book describes an important new technique that is useful to chemical and process engineering researchers, professionals, and students working with drying technologies.

Covers the engineering of complex nanostructures designed for applications in the peculiar space environment Deeply illustrates several examples of innovative manufacturing processes and creation of new products for the realization of advanced nanotechnological systems Identifies future efforts needed to further expand nanotechnology in space Presents a market analysis encompassing the whole area of strategic space-related applications

This book introduces charnolophagy (CP) as energy-driven, lysosomal-dependent mitochondrial inclusion-specific pleomorphic Charnoly body (CB) autophagy (ATG) involving free radical-induced Ca2+ dyshomeostasis, collapse, and ATP depletion in congenital diseases, pressure ulcers, metabolic diseases, hepatic diseases, diabetes, obesity, inflammatory diseases, musculoskeletal diseases, sarcopenia, cachexia, respiratory diseases, gastrointestinal diseases, hyperlipidemia, skin and hair diseases, pulmonary diseases, cardiovascular diseases, renal diseases, sepsis-induced multi-organ failure, reproductive diseases, inflammatory diseases, ophthalmic diseases, neurodegenerative diseases, drug addiction, aging, microbial (including COVID-19) infections, and belligerent malignancies implicated in early morbidity and mortality and disease-specific spatiotemporal, targeted, safe, and effective evidence-based personalized theranostic charnolopharmacotherapeutics to cure them. Basic DRESS and GELS principles, nanoparticles to cure chronic multidrug-resistant (MDR) diseases, antioxidants as free radical scavengers, CB antagonists, CP regulators, and CS stabilizers to curb CB molecular pathogenesis (CBMP) are described for better quality of life and longevity. Specific guidelines for environmental protection and preservation of zoological and botanical species at the verge of extinction, Triple "I" Hypothesis for mitochondrial quality control, and transcriptional regulation of CSexR and CSendoR to cure chronic diseases are presented. Novel CP index is introduced to evaluate MDR malignancies and other chronic diseases. WHO, CDC, FDA, NIH, policy planners, cosmetologists, trichologists, players, athletes, dancers, wrestlers, equestrians, young women, aging population, toxicologists, environmental protectionists, pharmaceutical industry, biomedical scientists, researchers, medical students, physicians, nurses, paramedical professionals, and global audience will be interested in this interesting book to prevent pandemics and raise healthcare awareness.