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Target Validation in Drug Discovery (Hardcover, New) Loot Price: R2,353
Discovery Miles 23 530
Repayment Terms: R221 pm x 12*
Target Validation in Drug Discovery (Hardcover, New): Brian W. Metcalf, Susan Dillon

Target Validation in Drug Discovery (Hardcover, New)

Brian W. Metcalf, Susan Dillon

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Loot Price R2,353 Discovery Miles 23 530 | Repayment Terms: R221 pm x 12*

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This work presents a comprehensive contemporary framework for approaching target validation in drug discovery. It begins with a detailed description of new enabling technologies, including aptamers, RNA interference, functional genomics, and proteomics. The next section looks at biologic drug development with in-depth discussion of lessons learned from such well-known cases as Erbitux, Herceptin, and Avastin. Additional targets known as "second generation" drugs, which can be identified when disease pathways are validated by biologics, present new possible small molecule therapeutics and serve as the focus of the final section of the book.

General

Imprint: Academic Press Inc
Country of origin: United States
Release date: November 2006
First published: September 2006
Editors: Brian W. Metcalf • Susan Dillon
Dimensions: 260 x 184 x 24mm (L x W x T)
Format: Hardcover
Pages: 296
Edition: New
ISBN-13: 978-0-12-369393-8
Categories: Books > Professional & Technical > Industrial chemistry & manufacturing technologies > Industrial chemistry > Pharmaceutical technology
Books > Academic & Education > Professional & Technical > Pharmacology
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LSN: 0-12-369393-4
Barcode: 9780123693938

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