Books > Medicine > Clinical & internal medicine > Diseases & disorders > Oncology
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Signaling Pathways in Cancer Pathogenesis and Therapy (Hardcover, 2012)
Loot Price: R2,779
Discovery Miles 27 790
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Signaling Pathways in Cancer Pathogenesis and Therapy (Hardcover, 2012)
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In recent years, increasing evidence has suggested that abnormal
activation of signaling pathways is a critical event in cancer
pathogenesis. In particular, activation of these pathways can lead
to inappropriate cellular survival, proliferation, pluripotency,
invasion, metastasis, and angiogenesis. Thus, understanding the
mechanisms by which signaling pathways become subverted in a cancer
cell can provide insight into critical events in cancer
pathogenesis. Furthermore, as our ability to target specific
molecular interactions advances, we now have the ability to design
small molecules, protein therapeutics, and other forms of targeted
therapies. By focusing on the specific molecular abnormalities in a
cancer cell, these agents hold the potential to be much more
effective and much less toxic than current cytotoxic therapies.
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