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After an extraordinary four-year battle, Gabi Lowe lost her beautiful, talented 20-year-old daughter, Jenna Lowe, on 8 June 2015 to pulmonary arterial hypertension, a rare degenerative lung disease, following a double lung transplant.
Jenna was young, bright and articulate. She was LEAD SA’s Youth Hero of the Year in 2015. Her death was mourned by thousands of people whose lives she had touched. During her short but full life, Jenna and the Lowe family raised much-needed awareness around this rare and devastating disease, highlighting the dire need for access to medication and organ donors locally. Although desperately ill, Jenna became the face for organ donation in South Africa through the hugely successful #GetMeTo21 campaign in which she invited all South Africans to attend her twenty-first birthday celebration by clicking on a link to become an organ donor. Tragically, Jenna died four months before reaching her milestone.
Brilliantly written, riveting in all its terrible truth and pain, in this brutally honest memoir Gabi Lowe shares her family’s desperate fight to save Jenna’s life. Get Me to 21 will inspire us to believe that the ability to face even the darkest, and most unimaginable, lives deep within us all.
Die oorlewingstog van 'n dapper vrou.
“ ŉ Kale vlakte waar my regterbors eens was. Ek maak my oë toe en laat my brein toe om te proe aan hierdie monumentale ding. Kanker schmanker, besluit ek. Ek is nog net soveel vrou soos voor die operasie. My vroulikheid het toe al die tyd nie in my bors gesit nie. Dit sit in my kop, in my hart, in daardie onmeetbare, onaantasbare iets wat die gees genoem word.”
In hierdie aangrypende boek deel die bekende spanningsverhaalskrywer Madelein Rust die intiemste besonderhede van haar reis met borskanker. Dit is ŉ brutaal eerlike vertelling wat haar belewenis van die siekte met patos en humor uitbeeld. Lesers verkry ŉ eiesoortige blik op die fisieke ervarings van borskankerstryders sowel as die ewig veranderende binnewêreld van dié wat teen die siekte veg.
Kanker schmanker! rus borskankerstryders toe met inligting wat nie altyd geredelik beskikbaar is nie en help hul geliefdes om die reis met kanker beter te verstaan. Dit is ŉ boek van hoop en triomf wat die leser hardop laat huil en laat lag. Dis 'n verhaal vir elkeen van ons wat ŉ stryd van enige aard stry.
Matthew Buckland built a business that employed 70+ people and counted Vodacom, Naspers, Mediclinic and J&B as clients. He fulfilled many an entrepreneur’s dream when he sold it to M&C Saatchi for millions, and stayed on as MD. But a few years later, he was out on his own again with a new venture and a new battle to fight: against cancer. So You Want to Build a Startup? is a frank, refreshing account of the difficulties – and the fun – of building a new-media business.
This comprehensive, superbly illustrated reference is designed to provide practical diagnostic assistance for hematopathologists when dealing with common and uncommon lesions in bone marrow trephine biopsies (BMTBs). At the heart of the book is a systematic analysis of neoplastic hematological and non-hematological disease entities, with concise identification of the key features of myeloproliferative neoplasms, myelodysplastic syndromes, acute and chronic leukemias, eosinophilia-associated myeloid/lymphoid neoplasms, lymphoproliferative disorders, and selected non-hematopoietic malignancies. Relevant examples of BMTBs are presented, with microscopic description, high-quality photomicrographs, and clinical data. The book also explains how to assess hematopoietic and stromal components of normal BMTBs, identifies the heterogeneous patterns that may be observed in healthy individuals, and analyzes reactive conditions, with particular attention to diagnostic problems and pitfalls.
TNM Classification of Malignant Tumours eighth edition provides the latest, internationally agreed-upon standards to describe and categorize cancer stage. * Published in affiliation with the Union for International Cancer Control (UICC) * Arranged by anatomical region, this authoritative pocket sized guide contains many important updated organ-specific classifications * There are new classifications for p16 positive oropharyngeal carcinomas, carcinomas of the thymus, neuroendocrine tumours of the pancreas, and sarcomas * To facilitate the collection of stage data for cancer surveillance in low and middle income countries there are new sections on Essential TNM and Paediatric Cancer Stage * New colour presentation
The AJCC Cancer Staging Manual and Handbook, prepared by the American Joint Committee on Cancer, are used by physicians and health care professionals throughout the world to facilitate the uniform description and reporting of neoplastic diseases. Proper classification and staging is essential for the physician to assign proper treatment, evaluate results of management and clinical trials, and to serve as the standard for local, regional and international reporting on cancer incidence and outcome. The seventh edition of the AJCC Cancer Staging Manual brings together all the currently available information on staging of cancer at various anatomic sites and incorporates newly acquired knowledge on the etiology and pathology of cancer. As knowledge of cancer biology expands, cancer staging must incorporate these advances. The current revision provides evidence-based staging based upon the established tenets of TNM classification supplemented by selected molecular markers. Relevant markers supported by evidence and of sufficient impact for treatment decisions have been included to define stage, for example Gleason's Score and PSA in prostate cancer Organized by disease site into 57 comprehensive chapters, the Seventh Edition features much-anticipated, major revisions to many chapters including breast, colon, prostate, kidney, and others. There are new primary site chapters for extrahepatic bile ducts, distal bile duct, cutaneous squamous cell carcinoma, Merkel cell carcinoma, and the adrenal gland plus a vastly expanded section on ophthalmologic malignancies User-friendly enhancements include: a revised and expanded presentation of the principles and rules of TNM staging a concise summary of changes in the TNM classification and "Staging at a Glance" opening each chapter to provide a snapshot of staging and coding details numerous new line drawings illustrating key sites throughout the text. full color text to highlight el
Male Breast Cancer: Taking Control is the third book by Professor John Boyages in his Breast Cancer: Taking Control series with a foreword by breast cancer survivor Nick Greiner. Professor John Boyages has helped thousands of people to not only survive but thrive after the diagnosis of breast cancer.John as he is known to his patients, writes the most comprehensive and easy to read books on breast cancer. Whether newly diagnosed or quite a way along your journey, his books are Australia's No.1 must-have read for patients.In Male Breast Cancer: Taking Control, John provides you with all the information you or your family and friends need to take control, maximize your survival, and find your path to recovery. It is also suitable for health professional staff and students.This book is written in John's approachable style, with more than 50 photographs and figures, patient stories and the use of botanical references and metaphors to explain difficult concepts easily. It is divided into three parts and has 20 control points where patients are guided through the process of making very important decisions regarding their diagnosis and treatment to put them in control. His first, award winning, best-selling book Breast Cancer: Taking Control was written for women with breast cancer and his second book DCIS of the Breast: Taking Control for patients with DCIS (ductal carcinoma in situ) or pre-cancerous cells of the breast. This third book Male Breast Cancer: Taking Control now completes the series. Learn how to: * Know the difference between "man boobs" and male breast cancer * Have the right tests for an earlier diagnosis * Avoid under- or overtreatment * Ask your treatment team the right questions * Choose treatments for your breast and lymph nodes * Deal with stress, anxiety, fatigue, and sexuality during and after treatment * Understand when chemotherapy is really required * Get specific up-to-date information for male breast cancer and avoid pamphlets designed for females * Achieve a more positive state of mind through inspiring and motivating patient stories and key take-home messages Some key features: * "Traffic-light" colors guide you through treatment phases * 20 color-coded "Control Points" * Clear end of chapter "Warning", "Tip" and "Remember" icons and summaries * End of chapter take home messages * 10 real-life patient stories * Plain English style with garden and other analogies to explain your breast cancer and its treatment * Over 50 images and graphically designed diagrams * Over 70 hand-picked web links * Detailed glossary, key references and index (print version) Within this book, there is a wealth of essential information and insight that I really wish had been available to me when I was diagnosed 10 years ago. This book will definitely help many men diagnosed with breast cancer now, and in the future, gain strength, support and a positive state of mind. - Herbert Paul Wagner, Male breast cancer survivor, advocate and CEO of A Man's Pink Although male breast cancer is rare it is important that men feel comfortable to talk about it, to note that this can happen and not to ignore the medical signs, as we men have a tendency to do! Male Breast Cancer: Taking Control fills the information gap for male breast cancer sufferers. -The Hon Nick Greiner AC Former Premier of New South Wales, Australia
This handbook provides a useful guide for the day-to-day management of people with breast cancer. It covers the journey from diagnosis to post-treatment comprehensive care. It explains when and why different treatment modalities are used, what the complications of both the disease and treatments are and how to manage them. Although this book has been written for students and health personnel working in a general hospital, it will be useful for those in specialist breast units as well. Dr Jenny Edge is a surgeon and head of Breast and Endocrine Surgery at the University of Stellenbosch. Dr Ines Buccimazza is head of the Breast Unit, member of the Multidisciplinary Breast Team and a senior specialist in the Department of Surgery at the Nelson R. Mandela School of Medicine at the University of KwaZulu-Natal in Durban.
It started with a simple question: How can we help them? It became an international movement called NEGU: Never Ever Give Up. When Jessica Joy Rees was diagnosed with an inoperable brain tumor at age 11, she chose to focus not on herself but on bringing joy and hope to other children suffering from cancer. During the ten months she battled cancer, she and her family worked in the "Joy Factory" (originally their garage) making JoyJars (R)-packages filled with toys, games, and love for other kids with cancer. Jessie first handed them out personally at the hospital where she was being treated, but the effort blossomed quickly and there were soon thousands of JoyJars (R) being distributed across the United States and to over fifteen countries. Today, more than 100,000 kids have received JoyJars (R), and they continue shipping each week to kids in over 200 children's hospitals and 175 Ronald McDonald Houses. Jessie lost her battle with cancer in January 2012, but her message lives on in the Jessie Rees Foundation, which has become a beacon of hope for families fighting pediatric cancer. Join the movement at www.negu.org.
Highly Commended in the category of Oncology at the British Medical Association Awards 2019 The accessible guide to the principles behind new, more targeted drug treatments for cancer Written for anyone who encounters cancer patients, cancer data or cancer terminology, but have no more than a passing knowledge of cell biology. A Beginner's Guide to Targeted Cancer Treatments provides an understanding of how cancer works and the many new treatments available. Using over 100 original illustrations, this accessible handbook covers the biology and mechanisms behind a huge range of targeted drug treatments, including many new immunotherapies. Dr Vickers translates a complex and often overwhelming topic into something digestible and easily understood. She also explains what cancer is, how it behaves and how our understanding of cancer has changed in recent years. Each chapter takes the reader through how new cancer drugs work and their benefits and limitations. With the help of this book, readers will be able to better understand more complex, in-depth articles in journals and books and develop their knowledge. This vital resource: Offers the latest insights into cancer biology Provides a broad understanding of how targeted cancer treatments work Describes many of the new immunotherapy approaches to cancer treatment, such as checkpoint inhibitors and CAR-modified T cells Helps readers feel confident discussing treatment options with colleagues and patients Provides an overview of which treatments are relevant to each of the most common solid tumours and haematological cancers, and the rationale behind them Demystifies the jargon - terms such as the EMT, cancer stem cells, monoclonal antibodies, kinase inhibitors, angiogenesis inhibitors etc. Explains the resistance mechanisms to many new treatments, including issues such as the way cancer cells diversify and evolve and the complex environment in which they live
Please visit www.cancerstaging.org for information about content updates and staging forms. The AJCC Cancer Staging Manual is used by physicians and health care professionals throughout the world to facilitate the uniform description and reporting of neoplastic diseases. Proper classification and staging of cancer is essential for the physician to assign proper treatment, evaluate results of management and clinical trials, and to serve as the standard for local, regional and international reporting on cancer incidence and outcome. Significantly expanded and developed by international disease site expert panels, the Eighth Edition AJCC Cancer Staging Manual brings together all the currently available knowledge on staging of cancer at various anatomic sites. In this edition, evidence-based TNM staging is supplemented, as appropriate, by selected molecular markers and newly acquired insights into the molecular underpinnings of cancer. This edition features 12 entirely new staging systems, a wide range of changed or new staging definitions, and a refined emphasis on a personalized-medicine approach. To enhance the print and electronic usability of the cancer staging forms, they are now available exclusively for access and downloading at www.cancerstaging.org. The Eighth Edition AJCC Cancer Staging Manual remains the gold standard reference for oncologists, surgeons, pathologists, radiologists, cancer registrars and medical professionals world-wide to ensure that all those caring for cancer patients are fully versed in the language of cancer staging.
Using his now familiar image of a garden and a personal, plain English style, renowned breast cancer specialist Professor John Boyages MD, PhD, walks you slowly through the stress and confusion of diagnosis, treatment, and life after DCIS of the breast. Your whole life stops after a diagnosis of DCIS. The condition is extremely confusing. Treatment advice varies and there is a danger of both undertreatment and overtreatment. One doctor recommends a lumpectomy and radiation and another recommends a mastectomy. One tells you it's a cancer and the other tells you it's not cancer. In"DCIS of the Breast: Taking Control," John Boyages provides you with all the information you, your family, and your friends need to take control, understand what DCIS is, and how to best treat this condition. Learn how to identify the twenty control points, and about the important decisions you must make to navigate the medical maze and take control if DCIS or cancer returns.
SPECT/CT cameras have considerably improved diagnostic accuracy in recent years. Such cameras allow direct correlation of anatomic and functional information, resulting in better localization and definition of scintigraphic findings. In addition to this anatomic referencing, CT coregistration provides superior quantification of radiotracer uptake based on the attenuation correction capabilities of CT. Useful applications of SPECT/CT have been identified not only in oncology but also in other specialties such as orthopedics and cardiology. This book covers the full spectrum of clinical applications of SPECT/CT in diagnosis and therapy planning of benign and malignant diseases. Opening chapters discuss the technology and physics of SPECT/CT and its use for dosimetry. The role of SPECT/CT in the imaging of a range of pathologic conditions is then addressed in detail. Applications covered include, among others, imaging of the thyroid, bone, and lungs, imaging of neuroendocrine tumors, cardiac scintigraphy, and sentinel node scintigraphy. Individual chapters are also devoted to therapy planning in selective internal radiation therapy of liver tumors and bremsstrahlung SPECT/CT. Readers will find this book to be an essential and up-to-date source of information on this invaluable hybrid imaging technique.
Depending on one's vantage point, breast cancer can be a very different experience, and indeed, a very different concern. It is, for some, a personal struggle; for others, it is a disease posing scientific and environmental challenges; and for others it is a highly charged and politicized issue around which policy wars rage. Beyond Slash, Burn, and Poison brings a unique perspective to breast cancer by recognizing the overlapping relationship of all these realities. Drawing on the writings of Rachel Carson, Betty Ford, Rose Kushner, and Audre Lorde, this book explores the various ways in which patient-centered texts continue to leave their mark on the political realm of breast cancer and, ultimately, the disease itself. Ordered chronologically, the selections trace the progression of discussions about breast cancer from a time when the subject was kept private and silent to when it became part of public discourse. The texts included are personal accounts, written by women struggling to play an active role in their healing process and, at the same time, hoping to help others do the same. Knopf-Newman also shows us how these writings eventually changed public opinion and the underlying tendency to blame women for their illness. She argues that changes in medical practice and public policy are linked to textual interventions, and makes a case for the politicization of cultural studies of disease through personal and literary expression. Passionately written and well-researched, Beyond Slash, Burn, and Poison transforms how we think about breast cancer. Rather than facilitating forums for separate discussions, this book brings conversations into dialog with each other. It is essentialreading for anyone concerned with breast cancer and its history, as well as for those interested in the effect of the environment on public health and the role that literature plays in public policy and medicine.
This book provides a comprehensive overview of the biological basis of renal tumors in childhood and the clinical approaches to their treatment. Recent advances in our understanding of the molecular genetics of Wilms and other renal tumors are placed in their clinical context, including the differing treatment approaches of immediate surgery or pre-operative chemotherapy. The challenges in applying this knowledge to improve risk stratification and to incorporate biologically targeted agents into front-line therapy are discussed. All of the authors are experts from Europe and North America and the book has been written specifically as an easy reference for the practising clinician and the research scientist. It lays the basis for understanding the future direction of clinical and translational research to improve outcomes in patients with childhood renal tumors and will prove indispensable for those treating or researching into these diseases.
Written by internationally renowned experts, Clinical Ophthalmic Oncology provides practical guidance and advice on the diagnosis and management of the complete range of ocular cancers. The book supplies all of the state-of-the-art knowledge required in order to identify these cancers early and to treat them as effectively as possible. Using the information provided, readers will be able to provide effective patient care using the latest knowledge on all aspects of ophthalmic oncology, to verify diagnostic conclusions based on comparison with numerous full-color clinical photographs, and to locate required information quickly owing to the clinically focused and user-friendly format. In this volume, the examination techniques, classification, and differential diagnosis of eyelid tumors and conjunctival and corneal tumors are carefully explained, and treatment options are considered in detail. "
On the night of December 2, 1943, the Luftwaffe bombed a critical Allied port in Bari, Italy, sinking seventeen ships and killing over a thousand servicemen and hundreds of civilians. Caught in the surprise air raid was the John Harvey, an American Liberty ship carrying a top-secret cargo of 2,000 mustard bombs to be used in retaliation if the Germans resorted to gas warfare. When one young sailor after another began suddenly dying of mysterious symptoms, Lieutenant Colonel Stewart Alexander, a doctor and chemical weapons expert, was dispatched to investigate. He quickly diagnosed mustard gas exposure, but was overruled by British officials determined to cover up the presence of poison gas in the devastating naval disaster, which the press dubbed "little Pearl Harbor." Prime Minister Winston Churchill and General Dwight D. Eisenhower acted in concert to suppress the truth, insisting the censorship was necessitated by military security. Alexander defied British port officials and heroically persevered in his investigation. His final report on the Bari casualties was immediately classified, but not before his breakthrough observations about the toxic effects of mustard on white blood cells caught the attention of Colonel Cornelius P. Rhoads-a pioneering physician and research scientist as brilliant as he was arrogant and self-destructive-who recognized that the poison was both a killer and a cure, and ushered in a new era of cancer research led by the Sloan Kettering Institute. Meanwhile, the Bari incident remained cloaked in military secrecy, resulting in lost records, misinformation, and considerable confusion about how a deadly chemical weapon came to be tamed for medical use. Deeply researched and beautifully written, The Great Secret is the remarkable story of how horrific tragedy gave birth to medical triumph.
The "Abtropfung" theory that nevi develop through the migration of nevus cells from the epidermis to the dermis prevailed for almost a century until the "Hochsteigerung" theory postulated the reverse pattern of migration. Most recently, however, new insights gained from epidemiology, cross-sectional and longitudinal studies of nevi, dermoscopy and confocal microscopy, and cellular and molecular studies have brought into question both of these theories. This book provides a comprehensive guide to current knowledge about nevogenesis by presenting these latest advances and in addition discusses issues yet to be resolved. It will assist practicing physicians in effectively managing patients with a variety of nevi and will also be of great value to researchers in the field. Importantly, since nevi are associated with an increased risk of melanoma, understanding nevogenesis may help to unravel some of the mysteries of melanomagenesis.
A revolutionary and definitive new approach to preventing breast cancer, from Board-certified world authority on breast health Dr. Kristi Funk, co-founder of the renowned Pink Lotus Breast Centre, and surgeon to Angelina Jolie and Sheryl Crow. Breasts: An Owner's Manual is a straight-talking, myth and misconception-busting, strategy-filled guide to breast health. Sharing the latest on lifestyle choices that impact your risk factor including food, supplements, hormones and exercise, Dr. Funk demonstrates that you are so much more in control of whether or not you get breast cancer than you could ever dare to think. In fact, unless you carry a genetic mutation associated with breast cancer, the choices you make in your-day-to-day life trumps genetics and family history when it comes to breast cancer risk, every time. Including a unique long-term risk reduction plan for every woman based on her needs, as well as the latest on diagnosis and treatment for women living with and surviving breast cancer, and with a heartfelt Foreword from longtime patient Sheryl Crow, this is a book with a life-saving message for the 1 in 8 women, at the time of writing, who are set to be diagnosed in their lifetime.
This book offers an image-based, comprehensive quick reference guide that will assist in the interpretation of contrast-enhanced ultrasound (CEUS) examinations of the liver in daily practice. It describes and depicts typical and atypical behavior of both common and less frequently observed focal liver lesions. For each type of lesion, the findings on pre- and post-contrast images are presented and key characteristics are highlighted. Individual chapters also focus on the assessment of response to locoregional and systemic treatment and the impact of European guidelines on CEUS. The Atlas of Contrast-Enhanced Sonography of Focal Liver Lesions will serve as an invaluable hands-on tool for practitioners who need to diagnose liver lesions using CEUS in the major clinical settings: oncology patients, cirrhotic patients, and patients with incidental focal liver lesions.
Kidney Cancer: Principles and Practice is a comprehensive and interdisciplinary textbook that encompasses all clinically relevant aspects of the disease. This new edition has been extensively updated and includes brand new material covering the most recent developments in kidney cancer diagnosis and therapy. The user-friendly and clinically oriented content of the book guarantees that it will be of great interest to a wide range of medical professionals, and every effort has been made to ensure that contributions are both easy to understand and directly related to patient care. Content presentation departs from the usual dense chapter format featuring a lengthy series of paragraphs. Instead, each chapter contains several boxed sections, including one that summarizes essential "take home points" for the busy clinician and another that presents a patient-oriented case highlighting the clinical application of elements discussed in that chapter. In addition, accessible original images, illustrations, and diagrams (some in full color) are used to simplify particularly complex material. This book will be of value for clinicians, researchers, residents, fellows, students, and knowledgeable lay people. The contributors comprise an international group of authors with expertise in kidney cancer epidemiology, molecular biology, pathology, diagnosis, clinical features, staging, prognostic and predictive factors, surgery, systemic therapy, and emerging investigational approaches, among others.
This book explains clearly the nature of colon polyps and their relationship with colorectal cancer, which is among the three most common cancers in both men and women. Up-to-date information is provided on anatomy, pathology, types of polyp and their treatment, and the performance of colonoscopy. Particular attention is devoted to the risk factors for development of colorectal cancer, with detailed guidance on its prevention and early diagnosis and treatment. While the book is primarily intended for medical specialists and students, a deliberate and consistent effort has been made to use plain language that will enable other interested persons, including patients, to understand all aspects of the subject.
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