This book acts as a primer for radiographers upon performing computed tomography (CT) examinations. The focus resides in radiation physics, radiobiology, anatomy, imaging protocols and image evaluation. It seeks to provide readers insight into the practical and innovative approaches within CT, backed up with key literature and examples in practice. Recent innovations and the importance of new technology to acquire enhanced quality remain a focal point. These are essential in understanding the importance of dose optimization, patient anatomy and common pathology observed. Patient care will remain central in this book, supported with a dedicated chapter discussing effective communication, patient education, informed consent, coupled with the assessment of laboratory results and vital signs. The editors draw from recent publications and clinical expertise, supported with the growing trend of technological advances utilized within the CT environment. Critically, this volume focuses on the role of CT for an array of audiences but, more specifically, undergraduate and postgraduate radiographers worldwide.

Now divided into four parts, the second edition of Cancer Pain delivers broad coverage of the issues that arise in the management of malignancy-related pain, from basic science, through end of life care and associated ethical issues, to therapies, both medical and complementary. Part One reviews basis considerations in cancer pain management, including epidemiology, pharmacology, history-taking and patient evaluation and teamworking. Part Two brings together the drug therapies for cancer pain, their underlying basis, and potential side-effects. Part Three covers the non-drug therapies, including nerve blocks, stimulation-induced analgesia, radiotherapy, complementary therapies and psychological interventions. The control of symptoms other than pain, so critical to cancer patients, is also considered here. Part Four describes special situations. Cancer pain management in children and older patients, and in the community setting, and pain in the dying patient and the cancer survivor are all covered here.

Advanced skin cancer is one that has already metastasized beyond its primary origin, or one that has invaded underlying tissues such that surgical resection either is technically impossible or would lead to an unacceptable functional or cosmetic outcome. These skin cancers present a complex problem that requires the input of multiple specialties to delineate the best management plan. National guidelines utilize the best available data to guide management decisions. However, there is considerable leeway within the guidelines, enabling the ultimate care decision to be molded to best fit each individual patient. This book aims to provide instructional examples of patient cases where the input of the multidisciplinary team is critical in providing the most suitable care plan for the patient. CONTENTS: Melanoma * Squamous Cell Carcinoma * Basal Cell Carcinoma * Cutaneous Lymphoma * Kaposi's Sarcoma * Dermatofibrosarcoma Protuberans * Merkel Cell Carcinoma * Rare Cancer Presentations

In 2000 the Department of Health issued a number of initiatives, with improving cancer treatment and research, and providing greater resources for cancer care being made a priority. Nurses and their colleague will be at the forefront of these changes.
The book presents specialized biological information on what cancer is, how it damages the body, and how cancer treatments work. Engaging, accessible and illustrated throughout, this unique text:
*explains the basic biology of cancer
*discusses the biology of wide range of common cancers
*identifies and explains the biological causes of cancer
*explains drug action in chemotherapy and analgesia
*explains the link between diet and cancer, and how diet is important in cancer therapy
*discusses the biological basis of a range of nursing skills linked to cancer.
This book will provide nurses with the essential knowledge required for working with cancer patient and their families, and will enable them to work with current and new forms of cancer treatment. It will also be of great use to clinical staff and nurse educators.

A groundbreaking, comprehensive guide for managing, treating and preventing cancer. It's a sad truth of our times that one in three people will experience cancer in their lifetime. By 2040, the probability will rise to one in two. Holistic Cancer Medicine is for cancer patients - from newly diagnosed to the late stage - as well as a comprehensive guide on how to reduce the risk of cancer in the first place. Dr Henning Saupe's programme focusses on how those affected by cancer can carry out treatment to cure or control the disease while maintaining quality of life. As the founder and director of Germany's leading complementary cancer clinic, Dr Saupe offers Holistic Cancer Medicine as the culmination of twenty-five years of experience treating the disease. Dr Saupe complements standard treatment models with less burdensome, less invasive and more natural methods. Dr Saupe identifies The Holistic Model of the Twelve Vital Fields, describing the dynamic interplay between, nutrition, circulation, the microbiome, mitochondrial health, acid-base balance, chronic infections and more. He shares innovative treatments that address specific imbalances in the twelve vital fields, as well as specific tumour-killing methods, such as insulin potentiation therapy (IPT), photodynamic therapy (PDT), local and whole-body hyperthermia and pulsating electromagnetic frequency therapy (PEMF). He also details inner-life training (ILT) and affirmations for both physical and emotional pain, as well as tools for palliative care. Holistic Cancer Medicine is not just for cancer patients, but relatives, friends and colleagues supporting loved ones through the stages of cancer. It is also for people seeking to prevent the disease. An essential read during a critical time of life, this is a groundbreaking book on cancer care with an essential and compassionate message - that a diagnosis of cancer and living a full, vibrant life are not mutually exclusive.

The growth in chemotherapy has led to a great need for all those involved to be familiar with safe procedures based on best evidence-based practice. Practical Chemotherapy: a multidisciplinary guide is a comprehensive and straightforward guide describing over 70 widely used chemotherapy regimens, helping to make their prescription and administration safer and less problematic. Checklists throughout the book are specifically tailored for the needs of each professional group involved in treatment, and are intended to help prevent potentially serious mistakes that can occur. This book is unique in its practical emphasis and will be invaluable for doctors, pharmacists and nurses working in oncology and haematology.

the generative and resistant value of human vulnerability the importance of vulnerability in motivating engagement with social networks and material ecologies for productive thinking, communication, and community how relational ethics emerge as important for social and communicative life

This handbook is a concise, thorough, and portable reference guide to the multitude of complex chemotherapy protocols and other frequently utilized medications in the field of Hematology/Oncology. Its inclusion of commonly used oncology regimens, guidelines for supportive care during administration and sections on pain control, antibiotic use and antiemesis guidelines set it apart from other "chemotherapy handbooks". The authors have prepared this book with the intention of improving the care of those suffering from cancer.

Encyclopedia of Cancer, Third Edition, Three Volume Set provides a comprehensive, up-to-date overview of the multiple facets of the disease, including research, treatment and societal impact. This new edition comprises 180 contributions from renown experts who present the latest in Mechanisms, Hallmarks of Cancer, Causes of Cancer, Prevention and Control, Diagnosis and Therapy, Pathology and the Genetics of specific Cancers. Readers will find a comprehensive overview of the main areas of oncology, including etiology, mechanisms, prevention, and treatments, from basic science to clinical applications and public health, all set alongside the latest advances and hot topics that have emerged since the previous edition. Topics of interest in the field, including genomics and epigenomics, our understanding of the causes of cancer and the approaches to preventing it (e.g., HPV vaccination, role of obesity and nutrition, molecular markers of environmental exposures), new screening techniques (e.g., low-dose CT for lung cancer) and improvements in the treatment of many cancers (e.g., breast cancer, lung adenocarcinoma) are comprehensively and authoritatively presented.

Contains key theory and copious clinical material * Subject poorly covered in the existing literature * Focus on work with cancer patients, but insights also applicable to many other serious conditions

* A highly illustrated guide and reference for haematologists, oncologists and clinical scientists * Guiding investigation, differential diagnosis, prognosis and treatment options Meeting the needs of haematologists, oncologists and clinical scientists for an up-to-date reference, this handbook provides a visual presentation of lymphoproliferative disorders, lymphoid leukaemias and plasma cell neoplasms. Each malignancy is surveyed based on molecular and cellular changes, including histochemistry, cytochemistry and relevant radiographs. Pertinent clinical information relating to clinical presentation, differential diagnosis and prognostic indicators are concisely outlined, using numerous graphics and citing key references in the field.

Offers comprehensive coverage of currently available cancer predictors, the most recent research on carcinogenicity, and the design and interpretation of carcinogenicity experiments. Presents mouse, rat, and human carcinogenicity data for the liver, kidney, breast, cervix, prostate, hematopoietic system, colon, skin, urinary bladder, mouth, stomach, thyroid, and pancreas.

Sphingolipids in Cancer, Volume 140, the latest release in the Advances in Cancer Research series, provides invaluable information on the exciting and fast-moving field of cancer research. Topics discussed in this updated volume include Mechanisms of ceramide-dependent cancer cell death, Sphingolipids as regulators of autophagy and endocytic trafficking, The role and function of sphingomyelin biosynthesis in the development of cancer, Neutral sphingomyelinases in cancer: Friend or foe?, Sphingolipid rendezvous at the crossroad of NAFLD and senescence, Ceramide signaling and p53 pathways, Sphingolipid regulation of RNA Biology in cancer phenotypes, The role of ceramide-1-phosphate in tumor cell survival and dissemination, and more.

Expanding on the highly successful first edition, this second edition of Proton Therapy Physics has been completely restructured and updated throughout, and includes several new chapters. Suitable for both newcomers in medical physics and more seasoned specialists in radiation oncology, this book provides an in-depth overview of the physics of this radiation therapy modality, eliminating the need to dig through information scattered across medical physics literature. After tracing the history of proton therapy, the book explores the atomic and nuclear physics background necessary for understanding proton interactions with tissue. The text then covers dosimetry, including beam delivery, shielding aspects, computer simulations, detector systems and measuring techniques for reference dosimetry. Important for daily operations, acceptance testing, commissioning, quality assurance and monitor unit calibrations are outlined. The book moves on to discussions of treatment planning for single- and multiple-field uniform doses, dose calculation concepts and algorithms, and precision and uncertainties for nonmoving and moving targets. Imaging for treatment guidance as well as treatment monitoring is outlined. Finally, the biological implications of using protons from a physics perspective are discussed. This book is an ideal practical guide for physicians, dosimetrists, radiation therapists, and physicists who already have some experience in radiation oncology. It is also an invaluable reference for graduate students in medical physics programs, physicians in their last year of medical school or residency, and those considering a career in medical physics. Features: Updated with the latest technologies and methods in the field, covering all delivery methods of proton therapy, including beam scanning and passive scattering Discusses clinical aspects, such as treatment planning and quality assurance Offers insight on the past, present, and future of proton therapy from a physics perspective

Using a practical, question-and-answer approach, Evidence-Based Practice of Palliative Medicine, 2nd Edition, helps you provide optimal care for patients and families who are dealing with serious illness. This unique reference focuses on patient and family/caregiver-centered care, highlighting the benefits of palliative care and best practices for delivery. The highly practical, user-friendly format sets it apart from other texts in the field, with concise, readable chapters organized around clinical questions that you're most likely to encounter in everyday care. Uniquely organized using a question-and-answer approach, making it easy to find answers to common questions asked by practitioners and patients.  Up-to-date, reader-friendly chapters explore interventions, assessment techniques, treatment modalities, recommendations and guidelines, communication techniques, and available resources for palliative care.  Expanded discussions on hospice in every chapter, and a new emphasis on pediatrics, with increased material on pediatric malignancies, developmental delays, cystic fibrosis, and perinatal palliative care.  New chapters on wellness of the palliative care practitioner, patients with opioid use disorders, telehealth in palliative care, health disparities, rural palliative care, caring for people with hematologic malignancies, integrative and alternative therapies, LGBTQ+ populations, mobile health technologies, and national palliative care implementation strategies.  High-quality evidence gathered and reviewed by leading experts in palliative medicine, including clinicians, educators, and researchers across a broad range of disciplines.  Numerous algorithms throughout help you make informed decisions, and "take-home” points in every chapter provide a quick summary of key content.  Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text and figures from the book on a variety of devices. 

"Autologous Stem Cell Transplantation" integrates basic research and clinical aspects underlying the most recent results in those malignant diseases where progress is most effective.
Recent evidence shows that higher doses are better in inducing higher cure rates in hematological neoplasias, although myeloblation related to dose intensity can be a limiting factor. The toxicity can now be controlled with autologous marrow and peripheral blood progenitor cell transplantation, used with or without growth factors. The combination of high dose chemoradiotherapy followed by re-infusion of autologous stem cells constitute a dramatic advance in the treatment of refactory and relapse hematological neoplasias.

Nausea and vomiting are two of the most common side-effects of anti-cancer treatment, and the discovery and clinical application of 5-hydroxytryptamine3 receptor antagonists has transformed the management of these side effects, resulting in a much improved quality of life for cancer patients. This text presents a detailed overview of the management of cancer-treatment induced emesis in a number of different treatment settings, and focuses on the mechanisms and use of 5-HT3 receptor antagonists. Contributions are also included from the points of view of the nurse and the patient.

A "brilliant" ("Fortune"), eye-opening history of the war on cancer, "The Truth in Small Doses" asks why we are losing this essential fight and charts a path forward.
Over the past half century, deaths from heart disease, stroke, and so many other killers have fallen dramatically. But cancer continues to kill with abandon. In 2013, despite a four-decade "war" against the disease that has cost hundreds of billions of dollars, more than 1.6 million Americans will be diagnosed with cancer and nearly six hundred thousand will die from it.
A decade ago, Clifton Leaf, a celebrated journalist and a cancer survivor himself, began to investigate why we had made such limited progress fighting this terrifying disease. The result is a gripping narrative that reveals why the public's immense investment in research has been badly misspent, why scientists seldom collaborate and share their data, why new drugs are so expensive yet routinely fail, and why our best hope for progress--brilliant young scientists--are now abandoning the search for a cure. "Through flowing prose Leaf delivers, alongside facts and data, stories on personalities involved in research, the fascinating process of solving an unusual and highly deadly cancer in Africa, and the heartbreaking realities of cancer treatment in children today. Leaf's extensively investigated treatise will resonate with researchers and patients frustrated by the bureaucratic woes he delineates. Public policy makers, grant reviewers, and pharmaceutical researchers alike must consider Leaf's indictment and proposed solutions" ("Publishers Weekly"). "The Truth in Small Doses" is that rare tale that will both outrage readers and inspire conversation and change.

Psychosocial Resource Variables in Cancer Studies reviews the literature on selected psychosocial resource variables in cancer in order to raise and examine conceptual and methodological issues and to offer suggestions for future directions in the field. It provides investigators and clinicians with a systematic treatment of the state of the art in research on specific resource factors and provides a careful consideration of more generic methodological and statistical issues in this research context.Editors Curbow and Somerfield define resources as aspects of a person or environment that are brought to bear on the maintenance or restoration of adaptation under taxing conditions. They hope Psychosocial Resource Variables in Cancer Studies is just the beginning of an ongoing discussion within the field of psychosocial oncology on the nature and use of resource variables. The book's topics are crucial since researchers appear to be committed to using resource variables to explain outcomes. Also, resource variables are increasingly considered as explanatory concepts in quality-of-life research.Psychosocial Resource Variables in Cancer Studies offers critical reviews of the major resource variables investigated in contemporary psychosocial oncology research. It provides timely information on vital issues in this research, emphasizing studies of the influence of personal and social resources on adaptation to cancer. Chapters cover topics such as: the use of resource variables in the explanation of individual differences in adaptation to cancer and cancer treatment theories, measures, and methodological issues in the use of perceived control the use of the transactional model of coping to examine issues surrounding coping and the management of cancer demands religion and spirituality as resources in coping with cancer social support in adaptation to cancer and survival the clinical usefulness of research on psychosocial resources major measures of psychological functioning in psychosocial oncology research statistical and analytical issues in the use of resource variables roles of qualitative and quantitative approaches in exploring resource variablesThe editors begin with an overview of the oncology field and offer comments on issues that can be generalized to all psychosocial resource variables. Next is a presentation of a series of review papers on selected resource variables, including perceived control, coping, religion and spirituality, and social support, followed by a discussion of the clinical utility of research on these resource variables. The book concludes with a discussion of important cross-cutting methodological issues, including the selection of psychological functioning outcome measures, the statistical analysis of resource variables, and quantitative versus qualitative approaches.Psychosocial Reource Variables in Cancer is a valuable reference and guide for health psychologists, clinical health psychologists, clinical social workers in oncology, medical sociologists, medical anthropologists, and oncology nurses. It may also serve as important reading material for courses in health psychology, physiological factors in health and illness, personality and diseases, and stress and coping.

This volume investigates the links between the incidence of diet-related cancers and dietary patterns within Europe. It presents current understanding of the major cancers thought to be caused by diet alongside detailed data on regional variations in dietary composition, and collates these sets of information to illustrate associations between foods and nutrients and the risk of cancer at specific sites. There is particular discussion of the role of fat, meat, fibre, cereals and fresh vegetables. The importance of the "Mediterranean diet", and regional variance in this diet within Europe, is examined. Japanese and US dietary evidence is also considered. This book highlights the debate on cancer and diet, and points the way ahead for important new research.

One in two of us will develop cancer at some point in our lives and yet many of us don't understand how cancers arise. How many different kinds of cancer are there? What treatments are available? What does the future hold in terms of developing new therapies? This book demystifies cancer by explaining the underlying cell and molecular biology in a clear and accessible style. It answers the questions commonly asked about cancer such as what causes cancer and how cancer develops. It explains how DNA makes proteins and how mutations can corrupt those proteins. It also gives an overview of current therapies and how treatments may advance over the next decades, as well as explaining what actions we can take to help prevent cancer developing. Understanding Cancer is an accessible and engaging introduction to cancer biology for any interested reader.

The Physics of Three Dimensional Radiation Therapy presents a broad study of the use of three-dimensional techniques in radiation therapy. These techniques are used to specify the target volume precisely and deliver radiation with precision to minimize damage to surrounding healthy tissue. The book discusses multimodality computed tomography, complex treatment planning software, advanced collimation techniques, proton radiotherapy, megavoltage imaging, and stereotactic radiosurgery. A review of the literature, numerous questions, and many illustrations make this book suitable for teaching a course.
The themes covered in this book are developed and expanded in Webb's The Physics of Conformal Radiotherapy and the two may be used together or in successive semesters for teaching purposes.