Novel Therapies in Head and Neck Cancer: Beyond the Horizon, Volume Twelve, provides a high-level synthesis of the latest treatments and outcomes relating to head and neck cancer. Chemotherapy and immunotherapy for those cancer types are rapidly evolving, and an updated source based on the expertise of internationally renowned researchers is necessary. This book discusses the outcome of recent trials using chemotherapy, novel approaches for HPV+ SCCA, cases in which immunotherapy is more likely to be successful, and precision medicine based on target therapies. Additionally, new approaches for rare diseases in head and neck and novel drug delivery platforms are presented. This book will be a very useful source so that students, scientists and clinicians who can be facile with the data, build on what is known, and continue to offer cutting-edge, validated therapies to all patients.

Advances in Cancer Research provides invaluable information on the exciting and fast-moving field of cancer research. Here, once again, outstanding and original reviews are presented on a variety of topics, including tumor dormancy, micro RNA, tumor angiogenesis, cancer in mouse models, liposome based chemo and autoimmunotherapy, signaling in angiogenesis, targeted cancer therapy, and regulatory t-cells.

This issue of PET Clinics focuses on Recent Advances in Imaging with PET, CT, and MR Techniques and is edited by Drs. Habib Zaidi, Abass Alavi and Drew A. Torigian. Articles will include: Total-body PET imaging: Developments in instrumentation; Prospects for total-body PET imaging using plastic scintillators; Total-body imaging: Potential clinical applications; New challenges for PET image reconstruction for total-body imaging; Advances in preclinical PET instrumentation; Applications of hybrid PET/MRI in CNS disorders; Applications of hybrid PET-MRI in MSK disorders; Assessment of total body atherosclerosis burden by PET-CT; Recent advances on CT and MR imaging in radiology; Potential impact of Total Body PET imaging in measuring global disease burden in systemic inflammatory disorders; Applications of PET-MRI in CV disorders; and more!

* A highly illustrated guide and reference for haematologists, oncologists and clinical scientists * Guiding investigation, differential diagnosis, prognosis and treatment options Meeting the needs of haematologists, oncologists and clinical scientists for an up-to-date reference, this handbook provides a visual presentation of lymphoproliferative disorders, lymphoid leukaemias and plasma cell neoplasms. Each malignancy is surveyed based on molecular and cellular changes, including histochemistry, cytochemistry and relevant radiographs. Pertinent clinical information relating to clinical presentation, differential diagnosis and prognostic indicators are concisely outlined, using numerous graphics and citing key references in the field.

A clear, concise, and essential guide providing key information about cancer survivors and their needs-and how those needs can best be met. Excellent Care for Cancer Survivors: A Guide to Fully Meet Their Needs in Medical Offices and in the Community is edited by the director of the Lance Armstrong Cancer Survivorship Program at the Dana Farber Cancer Institute and comprised of articles by experts from that prestigious institution, from the Harvard Medical School, and other leading cancer programs. Its goal is simple: to assure that the millions of cancer survivors in the United States get the help they need to live life to its fullest. This timely work, enriched by conversations with cancer survivors themselves, explains the array of challenges that may affect survivors, from physical needs to psychological, spiritual, sexual, and financial issues. Topics such as nutrition and exercise are also addressed, as are risk assessment, rehabilitation, and possible cognitive dysfunction after chemotherapy. A final section explains the nuts and bolts of starting a professional cancer survivorship program, from staffing to fundraising, exploring what can and is being done to help cancer survivors in different settings achieve optimal health and quality of life. Conversations with cancer survivors explaining the physical and psychological challenges/obstacles they face A listing of current cancer survivorship programs across the United States

Advances in Clinical Radiology was established to review the year's most important questions in clinical radiology. A distinguished editorial board, headed by Dr. Frank Miller, identifies key areas of major progress and controversy, and invites preeminent specialists to contribute original articles devoted to these topics. These insightful overviews in radiology bring concepts to a clinical level and explore their everday impact on patient care.

Hyaluronan biology is being recognized as an important regulator of cancer progression. Paradoxically, both hyaluronan (HA) and hyaluronidases, the enzymes that eliminate HA, have also been correlated with cancer progression. Hyaluronan, a long-chain polymer of the extracellular matrix, opens up tissue spaces through which cancer cells move and metastasize. It also confers motility upon cells through interactions of cell-surface HA with the cytoskeleton. Embryonic cells in the process of movement and proliferation use the same strategy. It is an example of how cancer cells have commandeered normal cellular processes for their own survival and spread. There are also parallels between cancer and wound healing, cancer occasionally being defined as a wound that does not heal.
The growing body of literature regarding this topic has recently progressed from describing the association of hyaluronan and hyaluronidase expression associated with different cancers, to understanding the mechanisms that drive tumor cell activation, proliferation, drug resistance, etc. No one source, however, discusses hyaluronan synthesis and catabolism, as well as the factors that regulate the balance. This book offers a comprehensive summary and cutting-edge insight into Hyaluronan biology, the role of the HA receptors, the hyaluronidase enzymes that degrade HA, as well as HA synthesis enzymes and their relationship to cancer.
* Offers a comprehensive summary and cutting-edge insight into Hyaluronan biology, the role of the HA receptors, the hyaluronidase enzymes that degrade HA, as well as HA synthesis enzymes and their relationship to cancer
* Chapters are written by the leading international authorities on this subject, from laboratories that focus on the investigation of hyaluronan in cancer initiation, progression, and dissemination
* Focuses on understanding the mechanisms that drive tumor cell activation, proliferation, and drug resistance

Waterborne Pathogens: Detection Methods and Applications, Second Edition, gives an overview of advanced and emerging technologies in the detection of a range of waterborne pathogens. In addition, the book presents existing methodologies, highlights where improvements can be made, includes applications, and touches on the ways in which new technologies can be applied in water management. Finally, the book addresses issues of sample preparation (from sampling, to concentration and enrichment), a key stage in any detection protocol.

As the likely first responder in an emergency, you need quick access to essential information on the potential complications of many different cancer types and treatments. The new edition of this trusted resource provides up-to-date information on the pathophysiology, complications, risks, treatment approaches, prognosis, assessment findings, and nursing and medical interventions for a wide range of cancers. It also offers valuable information to help you fulfill your role as care coordinator and patient advocate, including client education guidelines, discharge procedures, and strategies for helping the client and family deal with the impact of the disease's progression. A consistent format throughout helps you quickly find the information you need, no matter what the topic. This indispensable reference is written and reviewed by both oncology and acute care nurses, ensuring accuracy, currency, and clinical relevance. Coverage of each cancer includes pathophysiologic mechanisms, epidemiology and etiology, risk profile, prognosis, professional assessment criteria (PAC), nursing care and treatment, evidence-based practice update, patient teaching, nursing diagnoses or DSM-IV, evaluation and desired outcomes, and discharge planning with follow-up care, where needed. The latest prognosis statistics give you a realistic picture of the survival possibilities for your patients so you can provide the most appropriate nursing care and patient education. Multiple-choice review questions with answers and rationales at the end of each chapter help reinforce your understanding of key concepts and prepare you for certification examinations. Special boxes highlight pediatric-specific care considerations for working with children. Six new chapters - Biliary and Pancreatic Obstruction, Depression and Cognitive Dysfunction, Dyspnea and Airway Obstruction, GI Obstruction, Heart Failure, and Spiritual Distress - keep you up to date with the latest advances in oncology nursing. Evidence-based rationales in the nursing interventions help you apply the latest research findings to actual practice. Each chapter includes a new section on pathophysiology to help you understand the physiologic processes associated with each oncologic complication.

The "Advances in Cancer Research" series provides invaluable information on the exciting and fast-moving field of cancer research. This volume presents outstanding and original reviews on a variety of topics including RUNX Genes in Development and Cancer; The RNA Continent; The c-myc Promoter; Designer Self-Assembling Peptide Nanofiber Scaffolds for Study of 3-D Cell Biology and Beyond; and Dendritic Cells in Cancer Immunotherapy.

Drug Repurposing in Cancer Therapy: Approaches and Applications provides comprehensive and updated information from experts in basic science research and clinical practice on how existing drugs can be repurposed for cancer treatment. The book summarizes successful stories that may assist researchers in the field to better design their studies for new repurposing projects. Sections discuss specific topics such as in silico prediction and high throughput screening of repurposed drugs, drug repurposing for overcoming chemoresistance and eradicating cancer stem cells, and clinical investigation on combination of repurposed drug and anticancer therapy. Cancer researchers, oncologists, pharmacologists and several members of biomedical field who are interested in learning more about the use of existing drugs for different purposes in cancer therapy will find this to be a valuable resource.

This issue of Neuroimaging Clinics of North America focuses on State of the Art Evaluation of the Head and Neck and is edited by Dr. Ashok Srinivasan. Articles will include: Diffusion MR in the head and neck: Principles and applications; Perfusion imaging in the head and neck: Go with the flow; MR spectroscopy of the head and neck: Principles, applications and challenges; Technological improvements in head and neck MR: At the cutting edge; Dual Energy CT in head and neck imaging: Pushing the envelope; Role of Ultrasound in head and neck evaluation; PET imaging in the head and neck: Current state and future directions; Patient centric head and neck cancer radiation therapy: Role of advanced imaging; AI in head and neck imaging: Glimpse into the future; NIRADS: Principles and implementation; Common data elements in head and neck reporting; and more!