Originally published in 1993, this volume describes a complementary
selection of tests to those described in the companion volume Basic
Mutagenicity Tests (Cambridge University Press, 1990). These
supplementary tests were used to assess risks of in vitro
mutagenicity in those instances where the basic tests were
inconclusive. As such, these tests had an important role in the
assessment of the safety of compounds, drugs and chemicals. These
supplementary test and guidelines, originally drawn up by the
United Kingdom Environmental Mutagen Society (UKEMS) were fully
revised in this publication to take full account of different
regulatory guidelines and scientific advances. This volume will be
of value to anyone with aninterest in regulatory affairs,
mutagenicity testing and the registration of chemical products in
the UK and Europe.
General
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