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Handbook of Prenatal Diagnosis - Methods, Issues & Health Impacts (Hardcover)
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Handbook of Prenatal Diagnosis - Methods, Issues & Health Impacts (Hardcover)
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Prenatal diagnosis is a method to detect foetal disease before
delivery. Ideally, prevention of foetal exposure to harmful
influences begins before conception because all major organ systems
develop early in pregnancy, often before a woman realises that she
is pregnant. Prenatal diagnosis is composed of non-invasive and
invasive methods. This book summarises recent developments in the
field of non-invasive prenatal diagnosis (NIPD) through the use of
foetal cells and ffDNA in maternal circulation during pregnancy and
provides an overview of the possibilities for future clinical
applications. The various options for prenatal screening for Down
Syndrome (DS) is also outlined, in addition to current research
efforts made to improve non-invasive prenatal diagnosis based on
foetal cells, cell free foetal DNA and proteins present in maternal
circulation. Additionally, this book gives an overview of essential
aspects of primary prevention efforts and effecting factors
including age and socio-demographical factors, obstetric history,
maternal medical conditions, genetic disorders, psycho-social
issues and infections and vaccination. Other chapters in this book
discuss the close correlation between hypertensive dysfunction in
pregnancy and the development of cardiovascular diseases, the
various techniques and applications of MRI in foetal imaging, a
review of prenatal genetic diagnosis (PGD), the relation between
antithrombin congenital deficiency and high risk miscarriages and
recurrent abortions, and a review of literature on arthrogryposis
multiplex congenita, the occurrence of multiple joint contractures
at birth.
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