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Books > Science & Mathematics > Biology, life sciences > Cellular biology
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Vertebrate Embryogenesis - Embryological, Cellular, and Genetic Methods (Hardcover, 2011)
Loot Price: R4,404
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Vertebrate Embryogenesis - Embryological, Cellular, and Genetic Methods (Hardcover, 2011)
Series: Methods in Molecular Biology, 770
Expected to ship within 10 - 15 working days
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One of the striking findings of modern developmental biology has
been the high degree of conservation of signaling and developmental
mechanisms amongst different animal species. Such conservation
allows information learned from a given organism to be applicable
to other species, including humans, and has validated the use of a
few model systems to deduce general biological principles. In spite
of this underlying conservation, however, each species has unique
characteristics arising from its evolutionary history. Vertebrate
Embryogenesis: Embryological, Cellular and Genetic Methods attempts
to address the increasingly important need of straddling species
boundaries in the context of a single research program by compiling
research protocols used in a wide range of vertebrate species. In
fact, this volume has been designed so that readers can readily
find information on species other than the one with which they may
be most familiar. These protocols include not only embryological
methods, but also cellular and genetic approaches that have
complemented and expanded our understanding of embryonic
development. In addition, a number of chapters highlight a specific
method that is in principle applicable to multiple species, such as
TILLING and ZFN-mediated mutagenesis, the generation of Embryonic
Stem (ES) cell lines, and nuclear/oocyte transfer. Written in the
highly successful Methods in Molecular Biology (TM) series format,
chapters contain introductions to their respective topics, lists of
the necessary materials and reagents, step-by-step, readily
reproducible laboratory protocols, and notes on troubleshooting and
avoiding known pitfalls. Authoritative and accessible, Vertebrate
Embryogenesis: Embryological, Cellular and Genetic Methods serves
as an ideal guide to the molecular, cell, and developmental biology
community and will hopefully contribute to the ongoing collective
effort towards a better understanding of the beauty and logic of
vertebrate development.
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