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Books > Science & Mathematics > Biology, life sciences > Developmental biology

Blueprint - How DNA Makes Us Who We Are (Paperback): Robert Plomin Blueprint - How DNA Makes Us Who We Are (Paperback)
Robert Plomin 1
R257 R158 Discovery Miles 1 580 Save R99 (39%) Shipped within 7 - 12 working days

'Mind-blowing ... It is a hugely important book ... His story is crucial' Matt Ridley, The Times One of the world's top behavioural geneticists argues that we need a radical rethink about what makes us who we are The blueprint for our individuality lies in the 1% of DNA that differs between people. Our intellectual capacity, our introversion or extraversion, our vulnerability to mental illness, even whether we are a morning person - all of these aspects of our personality are profoundly shaped by our inherited DNA differences. In Blueprint, Robert Plomin, a pioneer in the field of behavioural genetics, draws on a lifetime's worth of research to make the case that DNA is the most important factor shaping who we are. Our families, schools and the environment around us are important, but they are not as influential as our genes. This is why, he argues, teachers and parents should accept children for who they are, rather than trying to mould them in certain directions. Even the environments we choose and the signal events that impact our lives, from divorce to addiction, are influenced by our genetic predispositions. Now, thanks to the DNA revolution, it is becoming possible to predict who we will become, at birth, from our DNA alone. As Plomin shows us, these developments have sweeping implications for how we think about parenting, education, and social mobility. A game-changing book by a leader in the field, Blueprint shows how the DNA present in the single cell with which we all begin our lives can impact our behaviour as adults.

The Origin of Higher Taxa - Palaeobiological, developmental, and ecological perspectives (Paperback): T.S. Kemp The Origin of Higher Taxa - Palaeobiological, developmental, and ecological perspectives (Paperback)
T.S. Kemp
R860 Discovery Miles 8 600 Shipped within 7 - 12 working days

How do radically new kinds of organisms evolve? The Origin of Higher Taxa addresses this essential question, specifically whether the emergence of higher taxa such as orders, classes, and phyla are the result of normal Darwinian evolution acting over a sufficiently long period of time, or whether unusual genetic events and particular environmental and ecological circumstances are also involved. Until very recently, the combination of an incomplete fossil record and a limited understanding about how raw mutations lead via modified ontogenic processes to significant phenotypic changes, effectively stymied scientific debate. However, it is now timely to revisit the question in the light of the discovery of considerable new fossil material (and new techniques for studying it), together with significant advances in our understanding of phenotypic development at the molecular level. This novel text incorporates evidence from morphology, palaeobiology, developmental biology, and ecology, to review those parts of the fossil record that illustrate something of the pattern of acquisition of derived characters in lineages leading to actual higher taxa as well as the environmental conditions under which they occurred. The author's original ideas are set within the context of a broad and balanced review of the latest research in the field. The result is a book which provides a concise, authoritative, and accessible overview of this fascinating subject for both students and researchers in evolutionary biology and palaeontology.

Evolution (Hardcover, Second Edition Media Update): Carl T. Bergstrom, Lee Alan Dugatkin Evolution (Hardcover, Second Edition Media Update)
Carl T. Bergstrom, Lee Alan Dugatkin
R2,414 Discovery Miles 24 140 Shipped within 7 - 12 working days

Bergstrom and Dugatkin's highly regarded text now offers an expanded InQuizitive course. InQuizitive provides adaptive learning activities for students. Its unique coaching pedagogy helps them learn important concepts and develop critical thinking skills. In addition, the text focuses on getting students to think like evolutionary biologists, with critical thinking questions throughout every chapter and expanded end-of-chapter problems emphasising data interpretation.

Blueprint - How DNA Makes Us Who We Are (Paperback): Robert Plomin Blueprint - How DNA Makes Us Who We Are (Paperback)
Robert Plomin 1
R320 R252 Discovery Miles 2 520 Save R68 (21%) Shipped within 4 - 8 working days

One of the world's top behavioural geneticists argues that we need a radical rethink about what makes us who we are The blueprint for our individuality lies in the 1% of DNA that differs between people. Our intellectual capacity, our introversion or extraversion, our vulnerability to mental illness, even whether we are a morning person - all of these aspects of our personality are profoundly shaped by our inherited DNA differences. In Blueprint, Robert Plomin, a pioneer in the field of behavioural genetics, draws on a lifetime's worth of research to make the case that DNA is the most important factor shaping who we are. Our families, schools and the environment around us are important, but they are not as influential as our genes. This is why, he argues, teachers and parents should accept children for who they are, rather than trying to mould them in certain directions. Even the environments we choose and the signal events that impact our lives, from divorce to addiction, are influenced by our genetic predispositions. Now, thanks to the DNA revolution, it is becoming possible to predict who we will become, at birth, from our DNA alone. As Plomin shows us, these developments have sweeping implications for how we think about parenting, education, and social mobility. A game-changing book by a leader in the field, Blueprint shows how the DNA present in the single cell with which we all begin our lives can impact our behaviour as adults.

Plant Biology and Biotechnology - Volume I: Plant Diversity, Organization, Function and Improvement (Hardcover, 1st ed. 2015):... Plant Biology and Biotechnology - Volume I: Plant Diversity, Organization, Function and Improvement (Hardcover, 1st ed. 2015)
Bir Bahadur, Manchikatla Venkat Rajam, Leela Sahijram, K.V. Krishnamurthy
R5,604 R4,401 Discovery Miles 44 010 Save R1,203 (21%) Shipped within 7 - 12 working days

This volume offers a much-needed compilation of essential reviews on diverse aspects of plant biology, written by eminent botanists. These reviews effectively cover a wide range of aspects of plant biology that have contemporary relevance. At the same time they integrate classical morphology with molecular biology, physiology with pattern formation, growth with genomics, development with morphogenesis, and classical crop-improvement techniques with modern breeding methodologies. Classical botany has been transformed into cutting-edge plant biology, thus providing the theoretical basis for plant biotechnology. It goes without saying that biotechnology has emerged as a powerful discipline of Biology in the last three decades. Biotechnological tools, techniques and information, used in combination with appropriate planning and execution, have already contributed significantly to economic growth and development. It is estimated that in the next decade or two, products and processes made possible by biotechnology will account for over 60% of worldwide commerce and output. There is, therefore, a need to arrive at a general understanding and common approach to issues related to the nature, possession, conservation and use of biodiversity, as it provides the raw material for biotechnology. More than 90% of the total requirements for the biotechnology industry are contributed by plants and microbes, in terms of goods and services. There are however substantial plant and microbial resources that are waiting for biotechnological exploitation in the near future through effective bioprospection. In order to exploit plants and microbes for their useful products and processes, we need to first understand their basic structure, organization, growth and development, cellular process and overall biology. We also need to identify and develop strategies to improve the productivity of plants. In view of the above, in this two-volume book on plant biology and biotechnology, the first volume is devoted to various aspects of plant biology and crop improvement. It includes 33 chapters contributed by 50 researchers, each of which is an expert in his/her own field of research. The book begins with an introductory chapter that gives a lucid account on the past, present and future of plant biology, thereby providing a perfect historical foundation for the chapters that follow. Four chapters are devoted to details on the structural and developmental aspects of the structures of plants and their principal organs. These chapters provide the molecular biological basis for the regulation of morphogenesis of the form of plants and their organs, involving control at the cellular and tissue levels. Details on biodiversity, the basic raw material for biotechnology, are discussed in a separate chapter, in which emphasis is placed on the genetic, species and ecosystem diversities and their conservation. Since fungi and other microbes form an important component of the overall biodiversity, special attention is paid to the treatment of fungi and other microbes in this volume. Four chapters respectively deal with an overview of fungi, arbuscularmycorrhizae and their relation to the sustenance of plant wealth, diversity and practical applications of mushrooms, and lichens (associated with a photobiont). Microbial endosymbionts associated with plants and phosphate solubilizing microbes in the rhizosphere of plants are exhaustively treated in two separate chapters. The reproductive strategies of bryophytes and an overview on Cycads form the subject matter of another two chapters, thus fulfilling the need to deal with the non-flowering Embryophyte group of plants. Angiosperms, the most important group of plants from a biotechnological perspective, are examined exhaustively in this volume. The chapters on angiosperms provide an overview and cover the genetic basis of flowers development, pre-and post-fertilization reproductive growth and development, seed biology and technology, plant secondary metabolism, photosynthesis, and plant volatile chemicals. A special effort has been made to include important topics on crop improvement in this volume. The importance of pollination services, apomixes, male sterility, induced mutations, polyploidy and climate changes is discussed, each in a separate chapter. Microalgalnutra-pharmaceuticals, vegetable-oil-based nutraceuticals and the importance of alien crop resources and underutilized crops for food and nutritional security form the topics of three other chapters in this volume. There is also a special chapter on the applications of remote sensing in the plant sciences, which also provides information on biodiversity distribution. The editors of this volume believe the wide range of basic topics on plant biology that have great relevance in biotechnology covered will be of great interest to students, researchers and teachers of botany and plant biotechnology alike.

Fertilization - The Beginning of Life (Paperback): Brian Dale Fertilization - The Beginning of Life (Paperback)
Brian Dale
R870 R659 Discovery Miles 6 590 Save R211 (24%) Shipped within 7 - 11 working days

This book introduces readers to the fascinating interaction of specialized gamete cells, forming the early embryo and a blueprint of new life. Readers will gain a thorough understanding of the complex physiological events and mechanical processes - such as ionic regulation, metabolism and intracellular signalling - to decipher cause and effect in fertilization. Wide-ranging in its approach, this book describes fertilization as a highly conserved mechanism throughout the animal kingdom, taking case studies from echinoderms, ascidians, amphibians and mammals through to other phyla. An excellent companion to undergraduate and postgraduate students of medicine, veterinary and biological sciences, this text provides an underpinning of the mechanisms of fertilization that inform assisted reproduction practice and research in medicine and agriculture. It explores the detailed phases before fertilization: the oocyte as a quiescent cell, attracting its partner gamete, followed by a cascade of pre-determined physiological events, to form the dynamic zygote cell; setting the scene for the early embryo, and beyond.

Essential Cell Biology (Book, 5th ed.): Bruce Alberts, Karen Hopkin, Alexander D Johnson, David Morgan, Martin Raff, Keith... Essential Cell Biology (Book, 5th ed.)
Bruce Alberts, Karen Hopkin, Alexander D Johnson, David Morgan, Martin Raff, …
R2,622 Discovery Miles 26 220 Shipped within 7 - 11 working days
The Serengeti Rules - The Quest to Discover How Life Works and Why It Matters - With a new Q&A with the author (Paperback,... The Serengeti Rules - The Quest to Discover How Life Works and Why It Matters - With a new Q&A with the author (Paperback, Revised edition)
Sean B. Carroll
R369 R266 Discovery Miles 2 660 Save R103 (28%) Shipped within 7 - 12 working days

How does life work? How does nature produce the right numbers of zebras and lions on the African savanna, or fish in the ocean? How do our bodies produce the right numbers of cells in our organs and bloodstream? In The Serengeti Rules, award-winning biologist and author Sean Carroll tells the stories of the pioneering scientists who sought the answers to such simple yet profoundly important questions, and shows how their discoveries matter for our health and the health of the planet we depend upon. One of the most important revelations about the natural world is that everything is regulated--there are rules that regulate the amount of every molecule in our bodies and rules that govern the numbers of every animal and plant in the wild. And the most surprising revelation about the rules that regulate life at such different scales is that they are remarkably similar--there is a common underlying logic of life. Carroll recounts how our deep knowledge of the rules and logic of the human body has spurred the advent of revolutionary life-saving medicines, and makes the compelling case that it is now time to use the Serengeti Rules to heal our ailing planet. A bold and inspiring synthesis by one of our most accomplished biologists and gifted storytellers, The Serengeti Rules is the first book to illuminate how life works at vastly different scales. Read it and you will never look at the world the same way again.

Blueprint - How DNA Makes Us Who We Are (Hardcover): Robert Plomin Blueprint - How DNA Makes Us Who We Are (Hardcover)
Robert Plomin 1
R467 R372 Discovery Miles 3 720 Save R95 (20%) Shipped within 7 - 12 working days

'A clear and engaging explanation of one of the hottest fields in science' Steven Pinker 'A hugely important book' Matt Ridley, The Times One of the world's top behavioural geneticists argues that we need a radical rethink about what makes us who we are The blueprint for our individuality lies in the 1% of DNA that differs between people. Our intellectual capacity, our introversion or extraversion, our vulnerability to mental illness, even whether we are a morning person - all of these aspects of our personality are profoundly shaped by our inherited DNA differences. In Blueprint, Robert Plomin, a pioneer in the field of behavioural genetics, draws on a lifetime's worth of research to make the case that DNA is the most important factor shaping who we are. Our families, schools and the environment around us are important, but they are not as influential as our genes. This is why, he argues, teachers and parents should accept children for who they are, rather than trying to mould them in certain directions. Even the environments we choose and the signal events that impact our lives, from divorce to addiction, are influenced by our genetic predispositions. Now, thanks to the DNA revolution, it is becoming possible to predict who we will become, at birth, from our DNA alone. As Plomin shows us, these developments have sweeping implications for how we think about parenting, education, and social mobility. A game-changing book by a leader in the field, Blueprint shows how the DNA present in the single cell with which we all begin our lives can impact our behaviour as adults.

Canto Classics - On Growth and Form (Paperback): D'Arcy Wentworth Thompson Canto Classics - On Growth and Form (Paperback)
D'Arcy Wentworth Thompson; Edited by John Tyler Bonner
R356 R292 Discovery Miles 2 920 Save R64 (18%) Shipped within 7 - 11 working days

Why do living things and physical phenomena take the form they do? D'Arcy Thompson's classic On Growth and Form looks at the way things grow and the shapes they take. Analysing biological processes in their mathematical and physical aspects, this historic work, first published in 1917, has also become renowned for the sheer poetry of its descriptions. A great scientist sensitive to the fascinations and beauty of the natural world tells of jumping fleas and slipper limpets; of buds and seeds; of bees' cells and rain drops; of the potter's thumb and the spider's web; of a film of soap and a bubble of oil; of a splash of a pebble in a pond.

Evolution's Bite - A Story of Teeth, Diet, and Human Origins (Hardcover): Peter Ungar Evolution's Bite - A Story of Teeth, Diet, and Human Origins (Hardcover)
Peter Ungar
R513 R402 Discovery Miles 4 020 Save R111 (22%) Shipped within 7 - 12 working days

What teeth can teach us about the evolution of the human species Whether we realize it or not, we carry in our mouths the legacy of our evolution. Our teeth are like living fossils that can be studied and compared to those of our ancestors to teach us how we became human. In Evolution's Bite, noted paleoanthropologist Peter Ungar brings together for the first time cutting-edge advances in understanding human evolution and climate change with new approaches to uncovering dietary clues from fossil teeth to present a remarkable investigation into the ways that teeth--their shape, chemistry, and wear--reveal how we came to be. Ungar describes how a tooth's "foodprints"--distinctive patterns of microscopic wear and tear--provide telltale details about what an animal actually ate in the past. These clues, combined with groundbreaking research in paleoclimatology, demonstrate how a changing climate altered the food options available to our ancestors, what Ungar calls the biospheric buffet. When diets change, species change, and Ungar traces how diet and an unpredictable climate determined who among our ancestors was winnowed out and who survived, as well as why we transitioned from the role of forager to farmer. By sifting through the evidence--and the scars on our teeth--Ungar makes the important case for what might or might not be the most natural diet for humans. Traveling the four corners of the globe and combining scientific breakthroughs with vivid narrative, Evolution's Bite presents a unique dental perspective on our astonishing human development.

Essential Cell Biology (Book, 5th ed.): Bruce Alberts, Karen Hopkin, Alexander D Johnson, David Morgan, Martin Raff, Keith... Essential Cell Biology (Book, 5th ed.)
Bruce Alberts, Karen Hopkin, Alexander D Johnson, David Morgan, Martin Raff, …
R3,332 Discovery Miles 33 320 Shipped within 7 - 11 working days
Superhuman - Life at the Extremes of Our Capacity (Hardcover): Rowan Hooper Superhuman - Life at the Extremes of Our Capacity (Hardcover)
Rowan Hooper
R494 R391 Discovery Miles 3 910 Save R103 (21%) Shipped within 7 - 11 working days
Fly Cycle 2 (CD-ROM): Mary S. Tyler, Ronald N. Kozlowski Fly Cycle 2 (CD-ROM)
Mary S. Tyler, Ronald N. Kozlowski
R610 Discovery Miles 6 100 Shipped within 7 - 12 working days

Published by Sinauer Associates, an imprint of Oxford University Press. Fly Cycle2 is a DVD adaptation of the film, Fly Cycle: The Lives of a Fly, Drosophila melanogaster (Mary S. Tyler, Jamie W. Schnetzer and David Tartaglia, Sinauer Associates, 1996). The DVD is formatted for Macintosh and Windows systems. It includes forty minutes of QuickTime movies, depicting details on the biology and life cycle of Drosophila-adult courting and mating, embryonic development, larval growth, imaginal discs and salivary glands, metamorphosis, and a gallery of mutants used in research. Fly Cycle2 is designed to be used at a number of educational levels. At high school and introductory undergraduate levels, it can acquaint students with the fruit fly life cycle and a number of the mutants used in introductory courses. For more advanced undergraduates in developmental biology and genetics courses, and for graduate students beginning their research on Drosophila, the DVD introduces the many specifics they will need to know, and techniques for examining the organism in detail. New on this DVD are: The DVD version features improved video and audio quality, and a new scene selection feature. Additional material is available from the Fly Cycle web page, including: a 40-page booklet that includes extensive information on each video segment, a complete set of instructions for laboratory study, and online puzzles and questions.

From Matter to Life - Information and Causality (Hardcover): Sara Imari Walker, Paul C.W. Davies, George F. R. Ellis From Matter to Life - Information and Causality (Hardcover)
Sara Imari Walker, Paul C.W. Davies, George F. R. Ellis
R665 R601 Discovery Miles 6 010 Save R64 (10%) Shipped within 7 - 12 working days

Recent advances suggest that the concept of information might hold the key to unravelling the mystery of life's nature and origin. Fresh insights from a broad and authoritative range of articulate and respected experts focus on the transition from matter to life, and hence reconcile the deep conceptual schism between the way we describe physical and biological systems. A unique cross-disciplinary perspective, drawing on expertise from philosophy, biology, chemistry, physics, and cognitive and social sciences, provides a new way to look at the deepest questions of our existence. This book addresses the role of information in life, and how it can make a difference to what we know about the world. Students, researchers, and all those interested in what life is and how it began will gain insights into the nature of life and its origins that touch on nearly every domain of science.

Principles of Development (Paperback, 6th Revised edition): Lewis Wolpert, Cheryll Tickle, Alfonso Martinez Arias Principles of Development (Paperback, 6th Revised edition)
Lewis Wolpert, Cheryll Tickle, Alfonso Martinez Arias
R1,329 R1,202 Discovery Miles 12 020 Save R127 (10%) Shipped within 7 - 12 working days

How does a single cell develop into myriad different specialised cell types, control the organization of these different cells into tissues and organs, and ultimately form an unimaginably complex living organism such as a human? Furthermore, how is it possible for some adult animals, but not others, to regenerate fully functioning limbs? Principles of Development opens up the fascinating field of developmental biology to those wanting to understand the answers to questions such as these. Cutting edge science is explained clearly and succinctly and is richly illustrated with a variety of custom drawn figures, animations, and links to online movies that show development happening in real time. The emphasis throughout the text is always on the key principles of development - the underlying processes shared by diverse groups of organisms. This focus on principles provides a framework on which a richer understanding of specific topics can be built. Moreover, extensive pedagogical support is provided, both in the book and online, making this text the complete package for those studying developmental biology. Online Resources For students: -Test your understanding with multiple choice questions and answer guidance to long-answer questions from the book -Gain a three dimensional perspective of development by watching the movies of developing model organisms -View the signalling pathway animations to see these complex processes broken down step by step -Expand your knowledge and guide your studies with the suggested web activities - Examine and interpret raw data obtained by Cheryll Tickle and members of her laboratory and presented in silico For registered adopters of the text: -Download the figures from the book to use in lectures and hand-outs -Help your students delve into the research literature with the Journal Club -Download the test bank or import it into your VLE -PowerPoint of In silico practicals to use in class

21st Century Extreme Longevity (Hardcover): Karen Kenney 21st Century Extreme Longevity (Hardcover)
Karen Kenney
R657 R619 Discovery Miles 6 190 Save R38 (6%) Shipped within 7 - 11 working days
Developmental Biology (Paperback, 11th Revised edition): Scott F. Gilbert, Michael J. F. Barresi Developmental Biology (Paperback, 11th Revised edition)
Scott F. Gilbert, Michael J. F. Barresi
R1,334 R1,207 Discovery Miles 12 070 Save R127 (10%) Shipped within 7 - 12 working days

Published by Sinauer Associates, an imprint of Oxford University Press. A classic gets a new coauthor and a new approach: Developmental Biology, Eleventh Edition, keeps the excellent writing, accuracy, and enthusiasm of the Gilbert Developmental Biology book, streamlines it, adds innovative electronic supplements, and creates a new textbook for those teaching Developmental Biology to a new generation. Several new modes of teaching are employed in the new Gilbert and Barresi textbook. The videos explaining development-as well as those from Mary Tyler's Vade Mecum-are referenced throughout the book, and several other valuable new elements have been added.

Darwin College Lectures, Series Number 29 - Development: Mechanisms of Change (Paperback): Torsten Krude, Sara T. Baker Darwin College Lectures, Series Number 29 - Development: Mechanisms of Change (Paperback)
Torsten Krude, Sara T. Baker
R351 Discovery Miles 3 510 Shipped within 7 - 12 working days

This volume collects essays from prominent intellectuals and public figures based on talks given at the 2015 Darwin College Lectures on the theme of 'development'. The writers are world-renowned experts in such diverse fields as architecture, astronomy, biology, climate science, economy, psychology, sports and technology. Development includes contributions from developmental biologist and Nobel laureate John B. Gurdon, Olympic gold medallist Katherine Grainger, astronomer and cosmologist Richard Ellis, developmental psychologist Bruce Hood, former Met Office Chief Scientist Julia Slingo, architect Michael Pawlyn, development economist Ha-Joon Chang and serial entrepreneur Hermann Hauser. While their perspectives and interpretations of development vary widely, their essays are linked by a common desire to describe and understand how things change, usually in the direction of ever-increasing complexity. Written with the lay reader in mind, this interdisciplinary book is a must-read for anybody interested in the mechanisms underlying the changes we see in the world around us.

Field and Laboratory Methods in Animal Cognition - A Comparative Guide (Paperback): Nereida Bueno-Guerra, Federica Amici Field and Laboratory Methods in Animal Cognition - A Comparative Guide (Paperback)
Nereida Bueno-Guerra, Federica Amici
R1,168 R885 Discovery Miles 8 850 Save R283 (24%) Shipped within 7 - 12 working days

Would you ask a honeybee to point at a screen and recognise a facial expression? Or ask an elephant to climb a tree? While humans and non-human species may inhabit the same world, it's likely that our perceptual worlds differ significantly. Emphasising Uexkull's concept of 'umwelt', this volume offers practical advice on how animal cognition can be successfully tested while avoiding anthropomorphic conclusions. The chapters describe the capabilities of a range of animals - from ants, to lizards to chimpanzees - revealing how to successfully investigate animal cognition across a variety of taxa. The book features contributions from leading cognition researchers, each offering a series of examples and practical tips drawn from their own experience. Together, the authors synthesise information on current field and laboratory methods, providing researchers and graduate students with methodological advice on how to formulate research questions, design experiments and adapt studies to different taxa.

Evolution's Bite - A Story of Teeth, Diet, and Human Origins (Paperback): Peter Ungar Evolution's Bite - A Story of Teeth, Diet, and Human Origins (Paperback)
Peter Ungar
R390 R283 Discovery Miles 2 830 Save R107 (27%) Shipped within 7 - 12 working days

Whether we realize it or not, we carry in our mouths the legacy of our evolution. Our teeth are like living fossils that can be studied and compared to those of our ancestors to teach us how we became human. In Evolution's Bite, noted paleoanthropologist Peter Ungar brings together for the first time cutting-edge advances in understanding human evolution with new approaches to uncovering dietary clues from fossil teeth. The result is a remarkable investigation into the ways that teeth--their shape, chemistry, and wear--reveal how we came to be. Traveling the four corners of the globe and combining scientific breakthroughs with vivid narrative, Evolution's Bite presents a unique dental perspective on our astonishing human development.

Deep Homology? - Uncanny Similarities of Humans and Flies Uncovered by Evo-Devo (Hardcover): Lewis I. Held Deep Homology? - Uncanny Similarities of Humans and Flies Uncovered by Evo-Devo (Hardcover)
Lewis I. Held
R1,420 R1,337 Discovery Miles 13 370 Save R83 (6%) Shipped within 7 - 12 working days

Humans and flies look nothing alike, yet their genetic circuits are remarkably similar. Here, Lewis I. Held, Jr compares the genetics and development of the two to review the evidence for deep homology, the biggest discovery from the emerging field of evolutionary developmental biology. Remnants of the operating system of our hypothetical common ancestor 600 million years ago are compared in chapters arranged by region of the body, from the nervous system, limbs and heart, to vision, hearing and smell. Concept maps provide a clear understanding of the complex subjects addressed, while encyclopaedic tables offer comprehensive inventories of genetic information. Written in an engaging style with a reference section listing thousands of relevant publications, this is a vital resource for scientific researchers, and graduate and undergraduate students.

Evolutionary Biology: Genome Evolution, Speciation, Coevolution and Origin of Life (Hardcover, 2014 ed.): Pierre Pontarotti Evolutionary Biology: Genome Evolution, Speciation, Coevolution and Origin of Life (Hardcover, 2014 ed.)
Pierre Pontarotti
R3,929 R3,153 Discovery Miles 31 530 Save R776 (20%) Shipped within 7 - 12 working days

This book includes the most essential contributions presented at the 17th Evolutionary Biology Meeting in Marseille, which took place in September 2013. It consists of 18 chapters organized according to the following categories: * Molecular and Genome Evolution * Phylogeography of Speciation and Coevolution * Exobiology and Origin of Life The aims of the annual meetings in Marseille, which bring together leading evolutionary biologists and other scientists using evolutionary biology concepts, e.g. for medical research, are to promote the exchange of ideas and to encourage interdisciplinary collaborations. Offering an overview of the latest findings in the field of evolutionary biology, this book represents an invaluable source of information for scientists, teachers and advanced students.

Neuronal Tissue-Nonspecific Alkaline Phosphatase (TNAP) (Hardcover, 1st ed. 2015): Caroline Fonta, Laszlo Negyessy Neuronal Tissue-Nonspecific Alkaline Phosphatase (TNAP) (Hardcover, 1st ed. 2015)
Caroline Fonta, Laszlo Negyessy
R4,873 R3,932 Discovery Miles 39 320 Save R941 (19%) Shipped within 7 - 12 working days

Phosphatases, such as TNAP are fundamental in regulating the roles of cellular, and consequently numerous body functions. TNAP is a ubiquitous enzyme with a wide spectrum of substrates and specificity. Regulation at the cellular level and the lack of TNAP activity is a lethal condition. Recent findings of a highly specific regional, laminar and subcellular localization of TNAP in the cerebral cortex indicates that in addition to its metabolic and skeletal functions, TNAP also plays a role in regulating cerebral functions, most probably cognition. In fact, TNAP disturbance could result in complex diseases such as epilepsy, developmental retardation and Alzheimer's disease. Available data suggest that, regarding brain functions, TNAP is a potentially important target of clinical research. This book aims to provide an overview of our current understanding of the functions of TNAP in the brain and on other tissues and organs.

The Origin Of Individuals (Hardcover): Jean-Jacques Kupiec The Origin Of Individuals (Hardcover)
Jean-Jacques Kupiec
R1,999 R1,857 Discovery Miles 18 570 Save R142 (7%) Shipped within 7 - 12 working days

In the 17th century, Descartes put forth the metaphor of the machine to explain the functioning of living beings. In the 18th century, La Mettrie extended the metaphor to man. The clock was then used as the paradigm of the machine. In the 20th century, this metaphor still held but the clock was replaced by a computer.

Nowadays, the organism is viewed as a robot obeying signals emanating from a computer program controlled by genetic information. This book shows that such a conception leads to contradictions not only in the theory of biology but also in its experimental research program, thereby impeding its development.

The analysis of this problem is based on the most recent experimental data obtained in molecular biology as well as the history and philosophy of biology. It shows that the machine theory did not succeed in breaking with Aristotles finalism.

The book presents a new approach to biological systems based on cellular Darwinism. Genes are ruled by probabilistic mechanisms allowing cells to differentiate stochastically. Embryo development is not governed by a determinist genetic program but by natural selection occurring among cell populations inside the organism.

This theory has considerable philosophical consequences. Man may be a machine but he is a random one.

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