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Books > Science & Mathematics > Biology, life sciences > Developmental biology
In 2016 Current Topics in Developmental Biology (CTDB) will celebrate its 50th or "golden" anniversary. To commemorate the founding of CTDB by Aron Moscona (1921-2009) and Alberto Monroy (1913-1986) in 1966, a two-volume set of CTDB (volumes 116 and 117), entitled Essays on Development, will be published by Academic Press/Elsevier in early 2016. The volumes are edited by Paul M. Wassarman, series editor of CTDB, and include contributions from dozens of outstanding developmental biologists from around the world. Overall, the essays provide critical reviews and discussion of developmental processes for a variety of model organisms. Many essays relate the history of a particular area of research, others personal experiences in research, and some are quite philosophical. Essays on Development provides a window onto the rich landscape of contemporary research in developmental biology and should be useful to both students and investigators for years to come.
Endocannabinoids, the latest volume in the International Review of Neurobiology series is a comprehensive overview of the state-of-the-art research into the neurobiology of migraines. It reviews the current knowledge and understanding in the field, and provides a starting point for researchers and practitioners entering the field.
Nicotine Use in Mental Illness and Neurological Disorders, a volume in the International Review of Neurobiology series, is a comprehensive overview of the state-of-the-art research into nicotine use in mental illness and neurological disorders. It reviews current knowledge and understanding, also provides a starting point for researchers and practitioners entering the field.
This book presents the latest developments in medicine and biology. Chapters include research on environmental risk factors for diabetic nephropathy; pre-endoscopic management of patients with hematemesis; the benefits of early diagnosis, halo fixation and/or ventral stabilization of dens-fractures in correspondence to age of the patient and fracture type; a discussion on how and to which extent heart rate variability (HRV) is acutely changed in diabetic ketoacidosis (DKA) or in hyperglycemic hyperosmolar syndrome (HHS); an evaluation of the anatomical, refractive and functional results of an innovative technique of deep anterior lamellar keratoplasty; the physical, emotional and quality of life aspects of patients with Cervical Dystonia; the current issues in medical literature regarding androgen use during menopause; an overall report on the benefits and limitations of human milk oligosaccharides (HMOs) mass spectrometry (MS) analysis; the classification methods of the X-ray cerebral angiograms; and the diagnosis and management of intraoperatively necrotizing fasciitis of the breast.
This volume in the International Review of Neurobiology series is a comprehensive overview of the state-of-the-art research into GIRK Potassium Channels. It reviews current knowledge and understanding and provides a starting point for researchers and practitioners entering the field.
The Maternal-to-Zygotic Transition provides users with an expert accounting of the mechanisms and functions of this transition in a range of animal and plant models. The book provides critical information on how maternal gene products program the initial development of all animal and plant embryos, then undergoing a series of events, termed the maternal-to-zygotic transition, during which maternal products are cleared and zygotic genome activation takes over the developmental control.
Omic Studies of Neurodegenerative Disease: Part B is part of a well-established international series on neuroscience that examines major areas of basic and clinical research, along with emerging and promising subfields. The book informs the reader on the current state of the studies used to evaluate the mechanisms, causes, and treatment of neurodegeneration through a combination of literature reviews and examples of current research.
Omic Studies of Neurodegenerative Disease: Part A is part of a well-established international series on neuroscience that examines major areas of basic and clinical research, along with emerging and promising subfields. The book informs the reader on the current state of the studies used to evaluate the mechanisms, causes, and treatment of neurodegeneration through a combination of literature reviews and examples of current research.
The field of genetics is rapidly evolving, and new medical breakthroughs are occurring as a result of advances in our knowledge of genetics. Advances in Genetics continually publishes important reviews of the broadest interest to geneticists and their colleagues in affiliated disciplines.
This textbook provides students with knowledge of neurogenetics, neurogenesis, neuronal specification and function, neuronal networks, learning and memory formation, brain evolution, and neurodegenerative diseases. Students are introduced to topics of classical developmental genetics as well as modern molecular and neurogenetic methods. Using a wealth of examples from current research, the textbook takes a strong applied approach. Using animal models such as Drosophila melanogaster and Caenorhabditis elegans as well as mammalian systems, the interrelationships between genes, neurons, nervous systems, and behaviour under normal and pathological conditions are illustrated. The textbook aims encourage students to address biological questions in neurogenetics and to think about the design of their own experiments. It targets primarily master and graduate students in neurobiology, but is also a valuable teaching tool for instructors in these fields.
Among the offspring of humans and other animals are occasional individuals that are malformed in whole or in part. The most grossly abnormal of these have been referred to from ancient times as monsters, because their birth was thought to foretell doom; the less severely affected are usually known as anomalies. This volume digs deeply into the cellular and molecular processes of embryonic development that go awry in such exceptional situations. It focuses on the physical mechanisms of how genes instruct cells to build anatomy, as well as the underlying forces of evolution that shaped these mechanisms over eons of geologic time. The narrative is framed in a historical perspective that should help students trying to make sense of these complex subjects. Each chapter is written in the style of a Sherlock Holmes story, starting with the clues and ending with a solution to the mystery.
The book integrates our understanding of the factors and processes underlying the evolution of multicellularity by providing several complementary perspectives (both theoretical and experimental) and using examples from various lineages in which multicellularity evolved. Recent years marked an increased interest in understanding how and why these transitions occurred, and data from various fields are providing new insights into the forces driving the several independent transitions to multicellular life as well as into the genetic and molecular basis for the evolution of this phenotype. The ultimate goal of this book is to facilitate the identification of general and unifying principles and mechanisms.
Extracellular matrix proteins are serious, common human diseases
that are caused by mutations in genes that encode these proteins.
This has spurred a great number of researchers to study the
extracellular matrix, sometimes by choice and sometimes by
necessity. Much progress has been made in the last decade towards
understanding what matrix proteins do and how cells interact with
and respond to them. Volume 15 is a compilation of reviews by
experts in their respective fields. The chapters in this book
address the biology of a broad spectrum of extracellular matrix
molecules and their functions in development and disease.
The first book on zoo/captive animal behavior and how this applies to welfare. Despite growing evidence of the need to implement more suitable, naturalistic practices into zoo animal welfare, it still seems to be somewhat overlooked - this book will address this oversight. Includes specific detail and examples focusing on taxa, a huge factor in managing animals in zoos that has not previously been addressed in this way. Covers invertebrates as well as vertebrate species. Would be a recommended or core text on Zoo Biology courses, BScs in Animal Science, and Animal Welfare MScs, as well as an invaluable practitioner reference. A lot of students interested in animal behaviour are interested in zoos. Each chapter covers species-specific content include the following information: Ecology and natural history as relevant to the zoo, behaviour and welfare measures based on ecological knowledge, feeding ecology and nutritional management, mating systems and reproductive characteristics, enrichment and behavioural diversity. The chapters are consistently formatted for ease of information, with end of chapter summaries, boxes with selected enrichment devices or welfare assessment methods for assessing welfare state, and directed reading of peer reviewed and other reputable sources that help advance care. A final Part explores welfare assessment tools, quality of life, veterinary interventions and evidence-based approaches. It looks at ways to increase the value of zoo and aquarium animals by enhancing visitor interest and visitor behaviour change. Also, research needs for keepers and how to build evidence into a daily routine, as well as management of native species programmes and the future of zoo research.
The terrestrial organisms of the Galapagos Islands live under conditions unlike those anywhere else. At the edge of a uniquely rich mid-ocean upwelling, their world is also free of mammalian predators and competitors, allowing them to live unbothered, exuberant lives. With its giant tortoises, marine iguanas, flightless cormorants, and forests of giant daisies, there's no question that this is a magnificent place. Long before people traversed the Earth, evolution endowed native species with adaptations to these special conditions and to perturbations like El Nino events and periodic droughts. As the islands have grown ever-more connected with humanity, those same adaptations now make its species vulnerable. Today, the islands are best viewed as one big social-ecological system where the ability of each native organism to survive and reproduce is a product of human activity in addition to ecological circumstances. In this book, William H. Durham takes readers on a tour of Galapagos and the organisms that inhabit these isolated volcanic islands. Exuberant Life offers a contemporary synthesis of what we know about the evolution of its curiously wonderful organisms, how they are faring in the tumultuous changing world around them, and how evolution can guide our efforts today for their conservation. The book highlights the ancestry of a dozen specific organisms in these islands, when and how they made it to the Galapagos, as well as how they have changed in the meantime. Durham traces the strengths and weaknesses of each species, arguing that the mismatch between natural challenges of their habitats and the challenges humans have recently added is the main task facing conservation efforts today. Such analysis often provides surprises and suggestions not yet considered, like the potential benefits to joint conservation efforts between tree finches and tree daisies, or ways in which the peculiar evolved behaviors of Nazca and blue-footed boobies can be used to benefit both species today. In each chapter, a social-ecological systems framework is used to highlight links between human impact, including climate change, and species status today, Historically, the Galapagos have played a central role in our understanding of evolution; what these islands now offer to teach us about conservation may well prove indispensable for the future of the planet.
Muscle Biology: The Life History of a Muscle looks at the story of a muscle from its embryonic beginnings, through its growth and ability to adapt to changing functional circumstances during adult life, to its eventual decline in both structure and function as old age progresses. Injury occurs to muscle during normal activity, after trauma, and during the source of certain diseases. Chapters on both muscle regeneration and muscle diseases emphasize the possibilities and limitsations of the healing capacity of muscle fibers. Muscle Biology begins with a brief review about the structure and function of a normal mature muscle and then proceeds to follow the developmental history of a muscle from the embryo to old age in a manner that gives the reader a perspective about not only developmental controls but also how at any stage of development a muscle is able to adapt to its functional environment. The book discusses both normal and abnormal changes in the muscle, the mechanisms behind those changes and how to mitigate deleterious changes from disease, 'normal' aging, and disuse/lack of physical activity. This is a must-have reference for students, researchers and practitioners in need of a comprehensive overview of muscle biology.
Human Growth and Development, Third Edition provides a comprehensive volume covering the biology of human growth and the genetic, endocrine, environmental, nutritional, and socio-economic factors that contribute towards its full expression. Human Growth and Development continues to be a valuable resource for researchers, professors and graduate students across the interdisciplinary area of human development. For the new edition, updates are made to all fourteen of the "core chapters" of the book which form the essential reading for a comprehensive understanding of human growth and development. Additionally, new special topics are covered including the interpretation of recently found sub-adult fossils that expand our understanding of the evolution of human growth and a discussion of the early pattern of growth and development as the developmental origins of risk for non-communicable diseases of adulthood. Human Growth and Development, Third Edition includes contributions from the well-known experts in the field and is the most reputable, comprehensive resource available.
Nematodes are small multicellular organisms that have been used as biological models since the 1960s. For example, Caenorhabditis elegans is a free-living nematode worm, about 1mm in length, that lives in temperate soil environments. It is made up of about 1000 cells, and has a short life cycle of only two weeks. It was the first multicellular organism to have its whole genome sequenced. The book summarizes the importance of nematodes as model organisms in the fields of genetics, developmental biology, neurobiology, pharmacology, nutrition, ecology and parasitology. Of interest to a broad audience across a wide spectrum of disciplines, this book is useful for biologists working on comparative studies to investigate biological processes across organisms; medical scientists and pharmacologists for exploration of drugs and medicine (including the use of genome editing to eliminate diseases); ecologists considering nematodes as indicators for environment changes; and parasitologists for host-parasite interactions. Many other researchers can use this book as a benchmark for the broad implications of nematology research on other aspects of science.
This textbook introduces readers to the scientific basics of cardiovascular medicine and biology. It covers not only developmental but also cellular and molecular aspects of normally functioning vasculature and the heart; importantly, it also addresses the mechanisms leading to and involved in specific cardiovascular diseases. Though the main emphasis is on novel therapies and potential therapeutic targets, specific controversial topics like cardiac remodeling and regenerative capacities are also addressed. All chapters were written by lecturers from the Imperial College London, in collaboration with their students from the College's BSc Programme in Medical Sciences with Cardiovascular Science. Bridging the gap between clinics and basic biology, the book offers a valuable guide for medical students, and for Master and PhD students in Cardiovascular Biomedicine.
There is a major demand for people with scientific training in a wide range of professions based on and maintaining relations with science. However, there is a lack of good first-hand information about alternative career paths to research. From entrepreneurship, industry and the media to government, public relations, activism and teaching, this is a readable guide to science based skills, lifestyles and career paths. The ever-narrowing pyramid of opportunities within an academic career structure, or the prospect of a life in the laboratory losing its attraction, mean that many who trained in science and engineering now look for alternative careers. Thirty role models who began by studying many different disciplines give personal guidance for graduates, postgraduates and early-career scientists in the life sciences, physical sciences and engineering. This book is an entertaining resource for ideas about, and directions into, the many fields which they may not be aware of or may not have considered.
Stem Cells: Scientific Facts and Fiction, Third Edition, provides a state-of-the-art overview on the field of stem cells and their current applications. The book incorporates the history and firsthand commentaries in the field from clinical and research leaders, covering interesting topics of note, including the first clinical trials to treat Parkinson disease, macular degeneration, and corneal replacement, the cloning of monkeys, the organoid field, and CRISPR-edited genomics. In addition, coverage of adult, embryonic stem cells and iPS cells is included. This new edition distinguishes itself from the multiplicity of websites about stem cells with a broad view of the field. |
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